Abstract：
INTRODUCTION:Danish healthcare seeks to improve cancer survival through improved diagnostics, rapid treatment and increased focus on cancer prevention and early help-seeking. In neuro-oncology, this has resulted in the Integrated Brain Cancer Pathway (IBCP). The paper explores how the pathway works in the initial phase in a clinical setting with emphasis on pathway criteria. MATERIAL AND METHODS:All patients admitted during the first two-year period to a regional neurology department in Denmark and fulfilling the IBCP inclusion criteria were included. Data regarding onset symptoms, diagnosis and time for diagnostic work-up were obtained and supplemented by a retrospective review of patient records. Sensitivities, specificities and positive predictive values of the inclusion criteria were calculated with magnetic resonance imaging scan of the cerebrum as index of validity. RESULTS:The strength of the pathway inclusion criteria was determined largely by the number of criteria fulfilled and by the type of predominant symptoms. The criteria identified the majority of patients with symptomatic brain malignancy and were also highly predictive of general structural brain lesions. CONCLUSION:The introduction of the pathway is a major step forward in the efforts to optimize brain cancer patients' illness trajectory. FUNDING:This study was funded by a grant from the Danish Ministry of Health and Interior Affairs 2009 and the Helen Rude Foundation and has been approved by the Danish Data Protection Agency. TRIAL REGISTRATION:not relevant.
journal_name
Dan Med Jjournal_title
Danish medical journalauthors
Laursen EL,Rasmussen BKsubject
Has Abstractpub_date
2012-05-01 00:00:00pages
A4437issue
5issn
2245-1919pii
A4437journal_volume
59pub_type
杂志文章abstract：INTRODUCTION:Vitamin D plays an important role in a broad range of organ functions, including the cardiovascular system. Only one study has tested the association between vitamin D deficiency and arrhythmia and it found no association. The aim of the present study was to evaluate the association between vitamin D defic...
journal_title：Danish medical journal
pub_type： 杂志文章
doi：
更新日期：2012-09-01 00:00:00
abstract：INTRODUCTION:The health authorities have recommended that face-to-face consultations be substituted by telephone consultations to reduce the risk of virus transmission in out-patient clinics during the coronavirus disease 2019 (COVID-19) pandemic. The aim of the present study was to assess the frequency of such telepho...
journal_title：Danish medical journal
pub_type： 杂志文章
doi：
更新日期：2020-06-23 00:00:00
abstract：:Kidney cancer (Renal Cell Carcinoma (RCC)) is one of the most deadly malignancies due to frequent late diagnosis and poor treatment options. Histologically, RCC embraces a wide variety of different subtypes with the clear cell variant (ccRCC) being the most common, accounting for 75-90% of all RCCs. At present, the su...
journal_title：Danish medical journal
pub_type： 杂志文章
doi：
更新日期：2017-10-01 00:00:00
abstract：INTRODUCTION:The Danish Adult Diabetes Database (DADD) annually reports a quality indicator for lipid-lowering treatment of type 2 diabetes mellitus (T2DM) patients. This retrospective cohort study aims to A) investigate the reasons for inadequate or lacking lipid-lowering treatment and to B) assess the validity of the...
journal_title：Danish medical journal
pub_type： 杂志文章
doi：
更新日期：2018-09-01 00:00:00
abstract：INTRODUCTION:Our aim was to study the association between pregnant women's referral status for occupational risk assessment, and their risk of preterm delivery (< 37 weeks), low birth weight (LBW) (< 2,500 g) and small for gestational age (SGA). METHODS:In a cohort study, 1,202 deliveries among pregnant women referred...
journal_title：Danish medical journal
pub_type： 杂志文章
doi：
更新日期：2015-08-01 00:00:00
abstract：INTRODUCTION:Severely painful or dysfunctional destroyed wrists can be reconstructed by fusion, interposition of soft-tissue or by arthroplasty using artificial materials. Total and partial wrist arthroplasty (T/PWA) has been used on a regular basis since the 1960's. The objective of this study was to review the litera...
journal_title：Danish medical journal
pub_type： 杂志文章,评审
doi：
更新日期：2014-05-01 00:00:00
abstract：INTRODUCTION:Adjuvant treatment of early-stage breast cancer has been associated with bone loss in randomised trials, but evidence from unselected populations is needed. In a single-center study, we assessed the annual percentage change in bone mineral density (∆BMDt) and risk of osteoporosis from two to five years aft...
journal_title：Danish medical journal
pub_type： 杂志文章
doi：
更新日期：2020-10-20 00:00:00
abstract：:Ischemia-reperfusion injuries occur when the blood supply to an organ or tissue is temporarily cut-off and then restored. Even though the restoration of blood flow is absolutely essential in preventing tissue death, the reperfusion of oxygenated blood to the oxygen-deprived areas may in itself augment the tissue damag...
journal_title：Danish medical journal
pub_type： 杂志文章,评审
doi：
更新日期：2015-04-01 00:00:00
abstract：INTRODUCTION:A routine follow-up urine sample (FUS) in the form of a midstream urine sample (MSU) is recommended after treatment for urinary tract infection (UTI) according to the Danish Paediatric Society (DPS) and "Lægehåndbogen" published by Danish Regions. We studied the effect of FUS with a focus on patients witho...
journal_title：Danish medical journal
pub_type： 杂志文章
doi：
更新日期：2015-01-01 00:00:00
abstract：INTRODUCTION:Patients with diabetes suffering from hypoglycaemia may be treated by a Mobile Emergency Care Unit (MECU) and are often released at the scene following treatment. Some of these patients experience secondary hypoglycaemia and require renewed treatment or admission to hospital. The present study was initiate...
journal_title：Danish medical journal
pub_type： 杂志文章
doi：
更新日期：2015-04-01 00:00:00
abstract：:Sudden Cardiac Death (SCD) in the young (aged 1-35 years), although presumably rare, is always a tragic and devastating event often occurring in apparently healthy persons. Through the last decades, research have been undertaken to estimate the incidence rate and underlying causes of these deaths. However, because aut...
journal_title：Danish medical journal
pub_type： 杂志文章
doi：
更新日期：2012-02-01 00:00:00
abstract：INTRODUCTION:Spontaneous reporting of adverse drug reactions (ADRs) is used for continuous risk-benefit evaluation of marketed pharmaceutical products and for signal detection. The Adverse Drug Event Manager (ADEM) is a service offered to clinicians employed at hospitals in the Capital Region of Denmark. The ADEM assis...
journal_title：Danish medical journal
pub_type： 杂志文章
doi：
更新日期：2017-01-01 00:00:00
abstract：INTRODUCTION:We investigated the frequency of con-sanguinity among the parents to newborns with inborn errors of metabolism (IEM) diagnosed by neonatal screening. METHODS:Data were obtained from 15 years of national newborn screening for selected IEM with autosomal recessive mode of inheritance. Among the 838,675 newb...
journal_title：Danish medical journal
pub_type： 杂志文章
doi：
更新日期：2018-10-01 00:00:00
abstract：INTRODUCTION:Tuberous sclerosis complex (TSC) is a rare autosomal dominant multi-organ disease. In TSC, epilepsy is frequent and often treatment refractory. Dysfunction of the tumour-suppressing hamartin/tuberin complex leads to an over-activated mammalian target of rapamycin (mTOR) signalling pathway and uncontrolled ...
journal_title：Danish medical journal
pub_type： 杂志文章
doi：
更新日期：2019-12-01 00:00:00
abstract：INTRODUCTION:When patients are transferred from intensive care units (ICUs) to general wards with a tracheostomy in situ, there is a risk of suboptimal care and increased morbidity. The aim of this study was to elucidate the management of patients with a tracheostomy in situ at discharge from the ICU to the ward. MATE...
journal_title：Danish medical journal
pub_type： 杂志文章
doi：
更新日期：2012-08-01 00:00:00
abstract：INTRODUCTION:Patient blood management strategies for total hip and knee arthroplasty are controversial. They range from pre-operative haemoglobin optimisation to intra- and post-operative interventions. The aim of this study was to assess the various treatment modalities with respect to blood loss, haemoglobin levels a...
journal_title：Danish medical journal
pub_type： 杂志文章,评审
doi：
更新日期：2015-12-01 00:00:00
abstract：INTRODUCTION:(99m)Tc-pertechnetate scintigraphy is much used in the evaluation of patients with nodular goitre. We investigated the ability of experienced observers to estimate the thyroid 24-h (131)I uptake (RAIU) and the thyroid volume by visual evaluation of the scintigram. MATERIAL AND METHODS:Two endocrinologists...
journal_title：Danish medical journal
pub_type： 杂志文章
doi：
更新日期：2014-02-01 00:00:00
abstract：INTRODUCTION:Tonsillectomy may be performed by several methods. It is continuously being discussed which method is preferable with regard to postoperative haemorrhage, pain, activity and nutrition. MATERIAL AND METHODS:The present study is a prospective non-randomized study of tonsillectomy. It included 198 patients a...
journal_title：Danish medical journal
pub_type： 临床试验,杂志文章
doi：
更新日期：2012-01-01 00:00:00
abstract：INTRODUCTION:Recently, we established that a group of obese children and adolescents had a higher blood pressure (BP) than a healthy control group. In the present study, we investigate whether the higher BP in the obese group was influenced by BP cuff sizes. METHODS:A total of 104 obese patients aged 10-18 years were ...
journal_title：Danish medical journal
pub_type： 临床试验,杂志文章
doi：
更新日期：2016-01-01 00:00:00
abstract：INTRODUCTION:Recent studies have reported an asso-ciation between the day of week of surgery and post-operative mortality, meaning that patients undergoing surgery at the end of the week or during weekends may be at higher risk. The aim of this study was to investigate the influence of the day of week of surgery on mor...
journal_title：Danish medical journal
pub_type： 杂志文章
doi：
更新日期：2019-07-01 00:00:00
abstract：INTRODUCTION:The prevalence of children and adolescents with overweight and obesity has tripled over the past 30 years. One in five children in Denmark is overweight, a condition which is accompanied by serious medical and psychosocial complications. So far, an overview of the Danish treatment of childhood overweight a...
journal_title：Danish medical journal
pub_type： 杂志文章,多中心研究
doi：
更新日期：2016-09-01 00:00:00
abstract：INTRODUCTION:Mechanical restraint and other forms of coercion may be used under certain circumstances at psych-iatric wards. The use of coercion receives considerable focus, yet little is known about its diurnal distribution. We examined the initiation of mechanical restraint, sedative drug administration, physical ret...
journal_title：Danish medical journal
pub_type： 杂志文章
doi：
更新日期：2017-08-01 00:00:00
abstract：INTRODUCTION:Due to disagreement on optimal timing of inguinal hernia repair in children, we explored how Danish surgeons plan repair in children at different ages and with different symptoms. METHODS:A validated questionnaire on timing of inguinal hernia repair in children was sent to all surgeons performing paediatr...
journal_title：Danish medical journal
pub_type： 杂志文章
doi：
更新日期：2020-12-22 00:00:00
abstract：INTRODUCTION:This study reports our experience with microscopic phonosurgery (PS) of benign lesions of the vocal folds. MATERIAL AND METHODS:During the five-year period from 2003 to 2007, a total of 97 patients had PS for vocal fold polyps (n = 63), vocal fold cysts (n = 17), vocal fold nodules (n = 12) or vocal fold ...
journal_title：Danish medical journal
pub_type： 杂志文章
doi：
更新日期：2013-02-01 00:00:00
abstract：:Asthma and allergies are today the most common chronic diseases in children and the leading causes of school absences, chronic medication usage, emergency department visits and hospitalizations, which affect all members of the family and represent a significant societal and scientific challenge. These highly prevalent...
journal_title：Danish medical journal
pub_type： 杂志文章,评审
doi：
更新日期：2016-08-01 00:00:00
abstract：INTRODUCTION:The use of positron emission tomography with 2-deoxy-2-18F-fluoro-D-glucose integrated with CT (18F-FDG-PET/CT) in oncology is common. Unexpected incidental findings are occasionally recognised and can represent clinically relevant lesions or conditions. This study aims to assess the occurrence, clinical s...
journal_title：Danish medical journal
pub_type： 杂志文章
doi：
更新日期：2020-09-07 00:00:00
abstract：:Today, sentinel lymph node dissection (SLND) has replaced axillary lymph node dissection (ALND) as standard procedure for staging of the axilla in the treatment of breast cancer. SLND can accurately stage the axilla by removing on average only two lymph nodes. Only in case of metastatic spread to sentinel nodes an ALN...
journal_title：Danish medical journal
pub_type： 杂志文章,评审
doi：
更新日期：2012-07-01 00:00:00
abstract：INTRODUCTION:Marfan syndrome is an autosomal, dominantly inherited disorder of the connective tissue. We report the clinical data and results of a genetic analysis of a large Danish Marfan family. METHODS:Sanger sequencing of FBN1 was initially performed on genomic DNA from the index patient. Subsequently, four affect...
journal_title：Danish medical journal
pub_type： 杂志文章
doi：
更新日期：2014-11-01 00:00:00
abstract：INTRODUCTION:Cell-free DNA testing (cfDNA testing) in maternal plasma has recently been implemented in Danish healthcare. Prior to that we wanted to evaluate the preferences among pregnant women, partners and health professionals regarding cfDNA testing compared with invasive prenatal diagnostics. METHODS:Responders w...
journal_title：Danish medical journal
pub_type： 杂志文章
doi：
更新日期：2018-05-01 00:00:00
abstract：INTRODUCTION:There is no consensus among hip surgeons in Denmark on how to follow up patients after total hip arthroplasty (THA). Agreement on the need for radiographic examinations is also lacking. The purpose of this study was to evaluate if routine outpatient post-operative radiographs, obtained three and 12 months ...
journal_title：Danish medical journal
pub_type： 杂志文章
doi：
更新日期：2013-04-01 00:00:00
