Protamine reversal of heparin affects platelet aggregation and activated clotting time after cardiopulmonary bypass.

abstract：BACKGROUND:Basic science studies suggest that perioperative immune impairment may augment the risk of cancer recurrence after otherwise potentially curative surgery. Despite its immunosuppressant properties, dexamethasone is commonly given to oncologic patients in an effort to reduce postoperative nausea and vomiting. ...

journal_title：Anesthesia and analgesia

authors： De Oliveira GS Jr,McCarthy R,Turan A,Schink JC,Fitzgerald PC,Sessler DI

更新日期：2014-06-01 00:00:00

abstract：UNLABELLED:Postoperative pain is a common reason for the delayed discharge and unanticipated hospital admission of out-patients. In this study, we examined the pattern of pain in ambulatory surgical patients and determined those factors that predict postoperative pain. Ten thousand eight consecutive ambulatory surgical...

journal_title：Anesthesia and analgesia

authors： Chung F,Ritchie E,Su J

更新日期：1997-10-01 00:00:00

abstract：UNLABELLED:To evaluate the influence of needle type on the lateral distribution of 0.5% hyperbaric bupivacaine, 30 patients undergoing lower limb surgery were placed in the lateral position with the side to be operated on dependent and underwent dural puncture by either a 25-gauge Whitacre (n = 15) or a 25-gauge Quinck...

journal_title：Anesthesia and analgesia

authors： Casati A,Fanelli G,Cappelleri G,Aldegheri G,Leoni A,Casaletti E,Torri G

更新日期：1998-08-01 00:00:00

abstract：UNLABELLED:With pressure support ventilation (PSV), each PSV breath is flow-cycled, and the breath termination criterion (TC) is usually nonadjustable. When TC does not match the interaction between the patient's inspiratory-expiratory efforts to the opening and closing of the inspiratory and expiratory valves, patient...

journal_title：Anesthesia and analgesia

authors： Tokioka H,Tanaka T,Ishizu T,Fukushima T,Iwaki T,Nakamura Y,Kosogabe Y

更新日期：2001-01-01 00:00:00

abstract：UNLABELLED:Surgery is associated with activation of neutrophils and their influx into affected tissue. The pathogenic role of superoxide production generated by activated neutrophils has been documented repeatedly. Ketamine suppresses neutrophil oxygen radical production in vitro. In the present study, we compared the ...

journal_title：Anesthesia and analgesia

authors： Zilberstein G,Levy R,Rachinsky M,Fisher A,Greemberg L,Shapira Y,Appelbaum A,Roytblat L

更新日期：2002-09-01 00:00:00

abstract：:A study was undertaken in 15 patients to compare measured and assumed arteriovenous oxygen (A-V O2) content differences and their effects on resultant shunt calculations. All patients were on volume ventilators and demonstrated a stable cardiovascular state. Simultaneous measurements of the O2 content of a pulmonary a...

journal_title：Anesthesia and analgesia

authors： Harrison RA,Davison R,Shapiro BA,Meyers SN

更新日期：1975-03-01 00:00:00

abstract：UNLABELLED:One-lung ventilation (OLV) induces an increase in pulmonary shunt sometimes associated with a decrease in PaO2 despite ventilation with 100% oxygen. PaO2 improvement has been reported in one-lung ventilated animals receiving IV almitrine, a pulmonary vasoconstrictor. We evaluated the ability of almitrine to ...

journal_title：Anesthesia and analgesia

authors： Moutafis M,Dalibon N,Liu N,Kuhlman G,Fischler M

更新日期：2002-04-01 00:00:00

abstract：BACKGROUND:Neonatal exposure to sevoflurane induces neurobehavioral and neuroendocrine abnormalities in exposed male rats (generation F0) and neurobehavioral, but not neuroendocrine, abnormalities in their male, but not female, offspring (generation F1). These effects of sevoflurane are accompanied by a hypermethylated...

journal_title：Anesthesia and analgesia

authors： Xu N,Lei L,Lin Y,Ju LS,Morey TE,Gravenstein N,Yang J,Martynyuk AE

更新日期：2020-10-01 00:00:00

abstract：:Perioperative thermal manipulations are usually directed at the skin surface because methods of directly warming the core are invasive or ineffective. However, inadequate heat flow between peripheral and core compartments will decrease the rate at which core temperature changes. We therefore determined whether core hy...

journal_title：Anesthesia and analgesia

authors： Plattner O,Xiong J,Sessler DI,Schmied H,Christensen R,Turakhia M,Dechert M,Clough D

更新日期：1996-05-01 00:00:00

abstract：:We present a case of extreme hemodilution in which appropriately crossmatched blood was not available. A 53-year-old man was admitted to our hospital because of hemorrhagic shock due to multiple stab wounds. His blood type was B, Rh negative, and his intravascular fluid volume was maintained with balanced salt solutio...

journal_title：Anesthesia and analgesia

authors： Dai J,Tu W,Yang Z,Lin R

更新日期：2010-11-01 00:00:00

abstract：UNLABELLED:The purpose of this study was to determine whether subhypnotic doses of propofol effectively relieve pruritus in women who received intrathecal morphine for postoperative analgesia after cesarean delivery. Twenty-nine women who developed pruritus after undergoing an elective cesarean section and receiving in...

journal_title：Anesthesia and analgesia

authors： Beilin Y,Bernstein HH,Zucker-Pinchoff B,Zahn J,Zenzen WJ

更新日期：1998-02-01 00:00:00

abstract：:One approach to elucidating the general anesthetic target has used genetic selection procedures, wherein animals are bred for sensitivity or resistance to general anesthetics and correlations are sought with a specific neuronal structural or functional defect. For example, murine strains have been developed that are e...

journal_title：Anesthesia and analgesia

authors： McCrae AF,Gallaher EJ,Winter PM,Firestone LL

更新日期：1993-06-01 00:00:00

abstract：BACKGROUND:Visualization with ultrasound during regional anesthesia may reduce the risk of intraneural injection and subsequent neurological symptoms but has not been formally assessed. Thus, we performed this randomized clinical trial comparing ultrasound versus nerve stimulator-guided interscalene blocks for shoulder...

journal_title：Anesthesia and analgesia

authors： Liu SS,Zayas VM,Gordon MA,Beathe JC,Maalouf DB,Paroli L,Liguori GA,Ortiz J,Buschiazzo V,Ngeow J,Shetty T,Ya Deau JT

更新日期：2009-07-01 00:00:00

abstract：:Previous perfluorocarbon (PFC) emulsions have been associated with transient adverse events (i.e., platelet activation, decreased platelet count, febrile responses, changes in hemodynamic function). The Phase I studies described in this report were parallel, randomized, double-blinded, placebo-controlled studies condu...

journal_title：Anesthesia and analgesia

authors： Leese PT,Noveck RJ,Shorr JS,Woods CM,Flaim KE,Keipert PE

更新日期：2000-10-01 00:00:00

abstract：:The analgesic effects of butorphanol tartrate and morphine sulfate were compared in 127 patients judged to have moderate to severe pain following major operations. The study was double-blind, and the drugs were given IM at several dosage levels. Scores for pain intensity and relief, as well as pain-intensity differenc...

journal_title：Anesthesia and analgesia

authors： Tavakoli M,Corssen G,Caruso FS

更新日期：1976-05-01 00:00:00

abstract：BACKGROUND:We evaluated the interaction of dopamine-proxymetacaine and dopamine- oxybuprocaine antinociception using isobolograms. METHODS:This experiment uses subcutaneous drug (proxymetacaine, oxybuprocaine, and dopamine) injections under the skin of the rat's back, thus simulating infiltration blocks. The dose-rela...

journal_title：Anesthesia and analgesia

authors： Chen YW,Chiu CC,Lin HT,Wang JJ,Hung CH

更新日期：2018-05-01 00:00:00

abstract：BACKGROUND:In this study, we compared the effectiveness of direct laryngoscopy (DL) and the GlideScope videolaryngoscope (GVL) for nasotracheal intubation, as judged by the time to intubation (TTI-the primary outcome) and the ease of intubation. METHODS:Seventy patients requiring nasotracheal intubation for elective s...

journal_title：Anesthesia and analgesia

authors： Jones PM,Armstrong KP,Armstrong PM,Cherry RA,Harle CC,Hoogstra J,Turkstra TP

更新日期：2008-07-01 00:00:00

abstract：BACKGROUND:Given the controversy regarding the use of droperidol and the high cost of the 5-HT3 antagonists, a cost-effective alternative for routine use as a prophylactic antiemetic would be desirable. We designed two parallel, randomized, double-blind sham and placebo-controlled studies to compare the early and late ...

journal_title：Anesthesia and analgesia

authors： White PF,Tang J,Song D,Coleman JE,Wender RH,Ogunnaike B,Sloninsky A,Kapu R,Shah M,Webb T

更新日期：2007-01-01 00:00:00

abstract：:A 2-mo-old infant with biliary atresia was scheduled for laparoscopic Kasai with robot assistance. Before surgery, a practice trial maneuvering the cumbersome robotic equipment was performed to ensure rapid access to the patient in case of emergency. IV access, tracheal intubation, and arterial line placement followed...

journal_title：Anesthesia and analgesia

authors： Mariano ER,Furukawa L,Woo RK,Albanese CT,Brock-Utne JG

更新日期：2004-12-01 00:00:00

abstract：OBJECTIVE:In this study we sought to identify differences in risk factors and outcome of critically ill patients with Candida albicans and non-albicans candidemia. METHODS:Nonimmunosuppressed, nonneutropenic patients with candidemia diagnosed after intensive care unit (ICU) admission were included in a prospective obs...

journal_title：Anesthesia and analgesia

authors： Dimopoulos G,Ntziora F,Rachiotis G,Armaganidis A,Falagas ME

更新日期：2008-02-01 00:00:00

abstract：UNLABELLED:Clinical pathways are being introduced by hospitals to reduce costs and control unnecessary variation in care. We studied 766 inpatients to measure the impact of a perioperative clinical pathway for patients undergoing knee replacement surgery on hospital costs. One hundred twenty patients underwent knee rep...

journal_title：Anesthesia and analgesia

authors： Macario A,Horne M,Goodman S,Vitez T,Dexter F,Heinen R,Brown B

更新日期：1998-05-01 00:00:00

abstract：BACKGROUND:Perioperative respiratory adverse events (PRAEs) account for the major cause of morbidity and mortality in children undergoing general anesthesia. In our institutional clinical practice, we suspected that African American children experienced untoward respiratory events more frequently than other racial grou...

journal_title：Anesthesia and analgesia

authors： Tariq S,Syed M,Martin T,Zhang X,Schmitz M

更新日期：2018-07-01 00:00:00

abstract：:Spine surgery has been growing rapidly as a neurosurgical operation, with an increase of 220% over a 15-year period. Intraoperative blood transfusion is a major outcome determinant of spine procedures. Various approaches, including pharmacologic and nonpharmacologic therapies, have been tested to decrease both intraop...

journal_title：Anesthesia and analgesia

authors： Willner D,Spennati V,Stohl S,Tosti G,Aloisio S,Bilotta F

更新日期：2016-11-01 00:00:00

abstract：BACKGROUND:This study investigated the clinical performance of a model-based, patient-individualized closed-loop (CL) control system for propofol administration using the bispectral index (BIS) as a controlled variable during the induction and maintenance of anesthesia with propofol and remifentanil and studied the inf...

journal_title：Anesthesia and analgesia

authors： Neckebroek M,Boldingh JHL,De Smet T,Struys MMRF

更新日期：2020-06-01 00:00:00

abstract：UNLABELLED:Linking physiological pharmacokinetic models to models of the cardiovascular system requires knowledge of the sites in the body that mediate a drug's cardiovascular effects. We examined the role of the coronary concentrations of propofol. Nine sheep anesthetized with isoflurane (2%) were instrumented acutely...

journal_title：Anesthesia and analgesia

authors： Zheng D,Upton RN,Martinez AM

更新日期：2003-06-01 00:00:00

abstract：BACKGROUND:Dexmedetomidine, a selective α2-adrenergic agonist currently approved for continuous intensive care unit sedation, is being widely evaluated for its role as a potential anesthetic. The closed-loop anesthesia delivery system (CLADS) is a method to automatically administer propofol total intravenous anesthesia...

journal_title：Anesthesia and analgesia

authors： Dutta A,Sethi N,Sood J,Panday BC,Gupta M,Choudhary P,Puri GD

更新日期：2019-07-01 00:00:00

abstract：UNLABELLED:Evidence suggests that early postischemic hyperemia is mediated by both neurological and vascular mechanisms. We hypothesized that if neuronal activity were primarily responsible for reperfusion hyperemia, then electrocerebral silence induced by intracarotid anesthetics (propofol and pentothal) would attenua...

journal_title：Anesthesia and analgesia

authors： Joshi S,Wang M,Nishanian EV,Emerson RG

更新日期：2004-05-01 00:00:00

abstract：:The sensitivity, specificity, and accuracy of the cobalt blue and ninhydrin sweat tests were compared with the sympathogalvanic response (SGR) in assessment of complete sympathetic blockade. Patients were randomly assigned to receive epidural administration of either preservative-free physiologic saline solution and 8...

journal_title：Anesthesia and analgesia

authors： Benzon HT,Cheng SC,Avram MJ,Molloy RE

更新日期：1985-04-01 00:00:00

abstract：:The purpose of this study was to examine the effects of dexmedetomidine, an alpha 2-adrenergic agonist, on cerebral blood flow and metabolic rate in dogs anesthetized with 0.64% isoflurane. After intubation and institution of mechanical ventilation, arterial, venous, pulmonary artery, and sagittal sinus catheters were...

journal_title：Anesthesia and analgesia

authors： Zornow MH,Fleischer JE,Scheller MS,Nakakimura K,Drummond JC

更新日期：1990-06-01 00:00:00

abstract：:Quantitative Sensory Testing (QST) is a psycho-physiological test used to identify dysfunction of individual nerve fiber types. In the present study, we investigated whether selective nerve fiber dysfunction, as assessed by QST, correlates with the effectiveness of epidural steroid injections (ESI) in patients with lu...

journal_title：Anesthesia and analgesia

authors： Schiff E,Eisenberg E

更新日期：2003-09-01 00:00:00