Ketamine attenuates neutrophil activation after cardiopulmonary bypass.

abstract：UNLABELLED:Local anesthetics inhibit binding of ligands to beta2-adrenergic receptors (beta2ARs), and, as a consequence, inhibit intracellular cAMP production. We hypothesized that among homologous local anesthetics, their avidity at inhibiting binding of tritiated dihydroalprenolol (3H-DHA) to beta2ARs would increase ...

journal_title：Anesthesia and analgesia

authors： Butterworth J,James RL,Grimes J

更新日期：1997-08-01 00:00:00

abstract：:In this prospective randomized, double-blind study, we investigated the effect of ondansetron on the lidocaine subarachnoid block. Fifty-four male patients scheduled for transurethral surgery under subarachnoid anesthesia received oral ondansetron 4 mg the evening before surgery and 4 mg IV 15 min before subarachnoid ...

journal_title：Anesthesia and analgesia

authors： Fassoulaki A,Melemeni A,Zotou M,Sarantopoulos C

更新日期：2005-06-01 00:00:00

abstract：:The fragility of erythrocytes from 21 patients undergoing in vitro skeletal muscle contracture testing for malignant hyperthermia (MH) susceptibility was examined. Osmotic fragility was determined by the degree of hemolysis in buffered saline solutions of decreasing osmotic strength. Halothane-induced fragility was de...

journal_title：Anesthesia and analgesia

authors： Kistler P,Fletcher JE,Rosenberg H

更新日期：1987-10-01 00:00:00

abstract：:Tracheal temperature--the temperature of the tracheal wall--is believed to reflect the core temperature. The trachea reacts quickly to temperature changes because it is surrounded by various large arteries and veins. Using the blood temperature from the cardiopulmonary bypass (CPB) and the jugular vein temperature as ...

journal_title：Anesthesia and analgesia

authors： Yamakage M,Kawana S,Watanabe H,Namiki A

更新日期：1993-04-01 00:00:00

abstract：:We designed a randomized, double-blind study to assess the analgesic efficacy and safety of perioperative ketorolac infusion in 95 patients undergoing cholecystectomy. The ketorolac group (n = 48) received premedication, combined with ketorolac 30 mg intramuscularly (IM), followed by a ketorolac continuous infusion (2...

journal_title：Anesthesia and analgesia

authors： Varrassi G,Panella L,Piroli A,Marinangeli F,Varrassi S,Wolman I,Niv D

更新日期：1994-03-01 00:00:00

abstract：IMPLICATIONS:Esophageal insufflation can occur simultaneously with venting from the drain tube during positive pressure ventilation with the ProSeal laryngeal mask airway. ...

journal_title：Anesthesia and analgesia

authors： Stix MS,Borromeo CJ,O'Connor CJ Jr

更新日期：2002-04-01 00:00:00

abstract：:The alpha 2-adrenergic receptor agonist dexmedetomidine produces an anesthetic state in a variety of species. Although its effects on cerebral blood flow and the electroencephalogram have been investigated, the effect of this drug on intracranial pressure (ICP) has not been reported previously. Dexmedetomidine therefo...

journal_title：Anesthesia and analgesia

authors： Zornow MH,Scheller MS,Sheehan PB,Strnat MA,Matsumoto M

更新日期：1992-08-01 00:00:00

abstract：:To further investigate possible prolongation of the frequency-corrected QT interval (QTc interval) after administration of droperidol (DRO), we studied 40 surgical patients who were randomly assigned to one of three groups, receiving an intravenous (IV) injection of either 0.1 mg/kg (Group 1, n = 10), 0.175 mg/kg (Gro...

journal_title：Anesthesia and analgesia

authors： Lischke V,Behne M,Doelken P,Schledt U,Probst S,Vettermann J

更新日期：1994-11-01 00:00:00

abstract：:In this study we attempted to define the minimal dosage of alfentanil (AF) needed in combination with nitrous oxide to provide satisfactory anesthetic conditions for lower abdominal gynecologic surgery. General anesthesia was induced in 12 women with AF (150 micrograms X kg-1) and 66% N2O in O2. An infusion of AF was ...

journal_title：Anesthesia and analgesia

authors： Ausems ME,Hug CC Jr,de Lange S

更新日期：1983-11-01 00:00:00

abstract：BACKGROUND:A new benzodiazepine, remimazolam, which is rapidly metabolized by tissue esterases to an inactive metabolite, has been developed to permit a fast onset, a short, predictable duration of sedative action, and a more rapid recovery profile than currently available drugs. We report on modeling of the data and s...

journal_title：Anesthesia and analgesia

authors： Wiltshire HR,Kilpatrick GJ,Tilbrook GS,Borkett KM

更新日期：2012-08-01 00:00:00

abstract：:In this prospective, randomized, placebo-controlled, double-blind trial we studied the effects of IV N-acetylcysteine for prevention of renal injury in patients undergoing abdominal aortic surgery. Seventy patients without previously documented renal dysfunction were randomly allocated to receive either N-acetylcystei...

journal_title：Anesthesia and analgesia

authors： Hynninen MS,Niemi TT,Pöyhiä R,Raininko EI,Salmenperä MT,Lepäntalo MJ,Railo MJ,Tallgren MK

更新日期：2006-06-01 00:00:00

abstract：BACKGROUND:Pulmonary complications related to residual neuromuscular blockade lead to morbidity and mortality. Using an interrupted time series design, we tested whether proportions of reintubation for respiratory failure or new noninvasive ventilation were changed after a system-wide transition of the standard reversa...

journal_title：Anesthesia and analgesia

authors： Krause M,McWilliams SK,Bullard KJ,Mayes LM,Jameson LC,Mikulich-Gilbertson SK,Fernandez-Bustamante A,Bartels K

更新日期：2020-07-01 00:00:00

abstract：:A method involving sodium fusion and analysis by fluoride electrode, which has been used for the determination of total fluorinated metabolites of fluorine-containing drugs in physiologic fluids, is shown to be inapplicable to volatile fluorinated metabolites of volatile fluorinated anesthetic agents. The yields of in...

journal_title：Anesthesia and analgesia

authors： Ivanetich KM,Bradshaw JJ,Brittain T

更新日期：1982-09-01 00:00:00

abstract：:Persistent postoperative opioid use is thought to contribute to the ongoing opioid epidemic in the United States. However, efforts to study and address the issue have been stymied by the lack of a standard definition, which has also hampered efforts to measure the incidence of and risk factors for persistent postopera...

journal_title：Anesthesia and analgesia

authors： Kent ML,Hurley RW,Oderda GM,Gordon DB,Sun E,Mythen M,Miller TE,Shaw AD,Gan TJ,Thacker JKM,McEvoy MD,POQI-4 Working Group.

更新日期：2019-08-01 00:00:00

abstract：:Rifampin is commonly used for the treatment of tuberculosis and staphylococcal infections, as well as for prevention of infection in cardiac valve and bone surgeries. We report a case of profound hypotension after anesthesia induction with propofol in a patient who was treated with two 600 mg doses of rifampin for pro...

journal_title：Anesthesia and analgesia

authors： Mirzakhani H,Nozari A,Ehrenfeld JM,Peterfreund R,Szabo M,Walsh JL,Jiang Y,Sandberg W,Rosow C,Wang J

更新日期：2013-07-01 00:00:00

abstract：:Both epidural and general anesthetics alter autonomic balance. However, the relative differences between epidural (EA) and general anesthetics (GA) with regard to cardiac and peripheral sympathovagal balance have not been described. Twenty consecutive patients scheduled for radical retropubic prostatectomy were random...

journal_title：Anesthesia and analgesia

authors： Fleisher LA,Frank SM,Shir Y,Estafanous M,Kelly S,Raja SN

更新日期：1994-07-01 00:00:00

abstract：:The fatal/anesthetic ratio (FAR) in 44 swine weighing 32.6 +/- 0.7 kg (SEM) was determined. Fatal anesthetic concentration (the numerator for FAR) was defined as the end-tidal concentration at which the pig lived at least 10 min, during experiments that involved step increments in anesthetic concentrations. Previously...

journal_title：Anesthesia and analgesia

authors： Roberts SL,Gilbert M,Tinker JH

更新日期：1987-06-01 00:00:00

abstract：UNLABELLED:Subarachnoid lidocaine has been the anesthetic of choice for outpatient spinal anesthesia. However, its use is associated with transient neurologic symptoms (TNS). Preservative-free formulations of 2-chloroprocaine are now available and may compare favorably with lidocaine for spinal anesthesia. In this doub...

journal_title：Anesthesia and analgesia

authors： Kouri ME,Kopacz DJ

更新日期：2004-01-01 00:00:00

abstract：INTRODUCTION:The preoperative encounter may offer a cost-effective opportunity for diabetes screening. METHODS:Three hundred forty-seven fasting patients had a preoperative glucose measurement determined from blood residue left on the IV needle, measured with an Accu-Chek glucometer (Roche Diagnostics, Indianapolis, I...

journal_title：Anesthesia and analgesia

authors： Grek S,Gravenstein N,Morey TE,Rice MJ

更新日期：2009-11-01 00:00:00

abstract：:We investigated the characteristics of hypoxemic fetoplacental vasoconstriction (HFPV) in the dual perfused, single isolated human placental cotyledon. Fetal arterial blood pressures (FAP) were measured in four cotyledons (Group 1) equilibrated with 21% oxygen (O2), 5% carbon dioxide (CO2), and nitrogen (N2) [control]...

journal_title：Anesthesia and analgesia

authors： Ramasubramanian R,Johnson RF,Downing JW,Minzter BH,Paschall RL

更新日期：2006-08-01 00:00:00

abstract：:Pneumothorax can develop during laparoscopy, particularly during laparoscopic fundoplication, since the left parietal pleura is exposed and can be torn during dissection in the diaphragmatic hiatus. Such an event will result in specific pathophysiologic changes, since CO2, under pressure in the abdominal cavity, will ...

journal_title：Anesthesia and analgesia

authors： Joris JL,Chiche JD,Lamy ML

更新日期：1995-11-01 00:00:00

abstract：BACKGROUND:We evaluated the interaction of dopamine-proxymetacaine and dopamine- oxybuprocaine antinociception using isobolograms. METHODS:This experiment uses subcutaneous drug (proxymetacaine, oxybuprocaine, and dopamine) injections under the skin of the rat's back, thus simulating infiltration blocks. The dose-rela...

journal_title：Anesthesia and analgesia

authors： Chen YW,Chiu CC,Lin HT,Wang JJ,Hung CH

更新日期：2018-05-01 00:00:00

abstract：BACKGROUND:Recent research suggests that 6% hydroxyethyl starch (HES) 130/0.4 is one of the most frequently used resuscitation fluids worldwide. The retraction of studies evaluating its use necessitates a reevaluation of available evidence regarding its safety and efficacy. METHODS:We performed a systematic review and...

journal_title：Anesthesia and analgesia

authors： Gattas DJ,Dan A,Myburgh J,Billot L,Lo S,Finfer S,CHEST Management Committee.

更新日期：2012-01-01 00:00:00

abstract：UNLABELLED:Clinical pathways are being introduced by hospitals to reduce costs and control unnecessary variation in care. We studied 766 inpatients to measure the impact of a perioperative clinical pathway for patients undergoing knee replacement surgery on hospital costs. One hundred twenty patients underwent knee rep...

journal_title：Anesthesia and analgesia

authors： Macario A,Horne M,Goodman S,Vitez T,Dexter F,Heinen R,Brown B

更新日期：1998-05-01 00:00:00

abstract：:We performed a systematic review of 28 studies that examined preoperative risk factors for postoperative renal failure. Included in the studies were 10,865 patients who underwent either vascular, cardiac, general, or biliary surgery. No two studies used the same criteria for acute renal failure. Variability in definit...

journal_title：Anesthesia and analgesia

authors： Novis BK,Roizen MF,Aronson S,Thisted RA

更新日期：1994-01-01 00:00:00

abstract：UNLABELLED:Atrial fibrillation is a common complication of coronary artery bypass graft (CABG) surgery that is associated with adverse patient outcomes. We evaluated whether preexisting abnormalities of cardiac structure or function detected with transesophageal echocardiography (TEE) are prevalent in patients later de...

journal_title：Anesthesia and analgesia

authors： Skubas NJ,Barzilai B,Hogue CW Jr

更新日期：2001-07-01 00:00:00

abstract：BACKGROUND:Propofol can be measured in exhaled gas. Exhaled and plasma propofol concentrations correlate well, but the relationship with tissue concentrations remains unknown. We thus evaluated the relationship between exhaled, plasma, and various tissue propofol concentrations. Because the drug acts in the brain, we f...

journal_title：Anesthesia and analgesia

authors： Müller-Wirtz LM,Maurer F,Brausch T,Kiefer D,Floss M,Doneit J,Volk T,Sessler DI,Fink T,Lehr T,Kreuer S

更新日期：2021-01-01 00:00:00

abstract：BACKGROUND:Individualizing arterial blood pressure (ABP) targets during cardiopulmonary bypass (CPB) based on cerebral blood flow (CBF) autoregulation monitoring may provide a more effective means for preventing cerebral hypoperfusion than the current standard of care. Autoregulation can be monitored in real time with ...

journal_title：Anesthesia and analgesia

authors： Ono M,Zheng Y,Joshi B,Sigl JC,Hogue CW

更新日期：2013-01-01 00:00:00

abstract：:Despite the wide use of droperidol to reduce nausea and vomiting in children, its pharmacokinetics have not been described in pediatric patients. Twelve ASA Class I-II children, undergoing tonsillectomy and adenoidectomy, received standardized anesthesia; none of the children received premedication. After induction of...

journal_title：Anesthesia and analgesia

authors： Grunwald Z,Torjman M,Schieren H,Bartkowski RR

更新日期：1993-06-01 00:00:00

abstract：:In this study, we assessed the relationship between brain estimated specific gravity (eSG) and clinical symptoms, therapeutic intensity level, and outcome in human traumatic brain injury (TBI). Brain weight, volume, and eSG of the noncontused hemispheric areas were measured from computed tomography (CT) DICOM images o...

journal_title：Anesthesia and analgesia

authors： Degos V,Lescot T,Zouaoui A,Hermann H,Préteux F,Coriat P,Puybasset L

更新日期：2006-11-01 00:00:00