Abstract:
:In January 1997, experts from the United States, Europe, and Japan gathered at Stanford University to review their collective experience with intracoronary and noncoronary stenting and to identify and prioritize issues requiring further clinical investigation. This report summarizes the discussions that took place during this stent summit. Knowledge of stent-tissue interaction from animal and human pathologic specimens was reviewed in the context of evolving stent designs. The relative merits of coil and slotted tubular stent designs were discussed. Stent deployment routines, including self-expansion, balloon expansion, and high-pressure delivery were debated. The potential for covered stents and coated stents was explored. Problems surrounding the routine deployment of stents were identified: small vessel disease, long lesions, bifurcation stenoses, vein graft disease, ostial disease, left main stenoses, and intrastent restenosis. The value of intravascular ultrasound, as an adjunct to stenting, was explored and debated. An algorithm for "provisional stenting" based on ultrasound criteria was developed. Noncoronary stenting of the aorta, iliacs, and carotids were discussed. Clinical applications that may lead to randomized clinical trials were identified.
journal_name
Am Heart Jjournal_title
American heart journalauthors
Oesterle SN,Whitbourn R,Fitzgerald PJ,Yeung AC,Stertzer SH,Dake MD,Yock PG,Virmani Rdoi
10.1016/s0002-8703(98)70004-3subject
Has Abstractpub_date
1998-10-01 00:00:00pages
578-99issue
4 Pt 1eissn
0002-8703issn
1097-6744pii
S0002870398000623journal_volume
136pub_type
杂志文章,评审abstract::Patients with syndrome X have been found to have an abnormal coronary blood flow reserve. The physical performance during exercise, however, has been incompletely investigated. Cardiopulmonary exercise testing (CPX) is a reliable noninvasive method to provide indexes of lung, heart, circulation, and muscle functions. ...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/0002-8703(93)90162-3
更新日期:1993-03-01 00:00:00
abstract:BACKGROUND:The aim of this study was to test the hypothesis that patients with atherosclerotic cardiovascular (CV) disease optimally treated on a statin but with residual atherogenic dyslipidemia (low high-density lipoprotein cholesterol [HDL-C] and high triglycerides) will benefit from addition of niacin with fewer CV...
journal_title:American heart journal
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1016/j.ahj.2010.11.017
更新日期:2011-03-01 00:00:00
abstract:BACKGROUND:Procoagulant stress responses may contribute to atherosclerosis development and acute coronary thrombosis. In the present study, we examined the role of beta2-adrenergic receptor function and plasma catecholamines in the stress-induced increase in the 2 hypercoagulability markers thrombin-antithrombin III (T...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1067/mhj.2002.123146
更新日期:2002-07-01 00:00:00
abstract:BACKGROUND:Few telemedicine programs have undergone cost analyses, impeding their implementation into practice. We report on the economic analysis of a nurse-administered intervention designed to improve blood pressure control among hypertensive veterans. METHODS:We randomized hypertensive patients at the Durham Veter...
journal_title:American heart journal
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.ahj.2010.05.024
更新日期:2010-08-01 00:00:00
abstract::Twenty-six patients with Ebstein's anomaly were classified into three types according to their clinical features, heart catheterization data, angiocardiographic and anatomical findings which were obtained on surgery or autopsy. The hemodynamics in each type were discussed. 1. Tricuspid Stenosis Dominant Type. Eight pa...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/0002-8703(78)90458-1
更新日期:1978-02-01 00:00:00
abstract:BACKGROUND:Many chronic heart failure (CHF) patients have low vitamin D (VitD) and high plasma renin activity (PRA), which are both associated with poor prognosis. Vitamin D may inhibit renin transcription and lower PRA. We investigated whether vitamin D3 (VitD3) supplementation lowers PRA in CHF patients. METHODS AND...
journal_title:American heart journal
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.ahj.2013.05.009
更新日期:2013-08-01 00:00:00
abstract::To evaluate the risk factors for coronary disease, 345 women, aged 35 to 59 years, who had undergone coronary arteriography for suspected coronary disease completed a mail questionnaire, telephone interview, or both. Two hundred eight women with angiographically normal coronary arteries constituted the control group, ...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/0002-8703(89)90398-0
更新日期:1989-06-01 00:00:00
abstract::The effects of two regimens for the initiation of amiodarone therapy were compared in 92 patients with inducible sustained ventricular tachycardia (VT) at baseline electrophysiologic testing. Two groups of 46 patients each received a total of 16.8 gm of oral amiodarone before follow-up electrophysiologic testing. Grou...
journal_title:American heart journal
pub_type: 临床试验,杂志文章
doi:10.1016/0002-8703(92)90599-q
更新日期:1992-08-01 00:00:00
abstract::Twenty-seven patients with asymptomatic, nonsustained ventricular tachycardia whose evaluation suggested they were at high risk for sustained ventricular arrhythmias were treated with implantable cardioverter defibrillators. The option of conventional therapy (including the option of no therapy) was presented to each ...
journal_title:American heart journal
pub_type: 杂志文章,多中心研究
doi:10.1016/s0002-8703(96)90051-4
更新日期:1996-01-01 00:00:00
abstract::Two double-blind multicenter studies compared acebutolol with placebo (acebutolol, N = 121; placebo, N = 116) and with propranolol (acebutolol, N = 186; propranolol, N = 190) in essential hypertension. Acebutolol significantly reduced mean sitting diastolic blood pressure from 99.2 +/- 0.3 mm Hg at baseline to 89.1 +/...
journal_title:American heart journal
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/0002-8703(85)90702-1
更新日期:1985-05-01 00:00:00
abstract::The duration of intravenous heparin therapy required to maintain patency of the infarct-related artery after intravenous streptokinase is uncertain. Twenty-eight patients were prospectively treated with 1.5 million units of intravenous streptokinase within 4 hours of onset of chest pain. Intravenous heparin was begun ...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/0002-8703(88)90870-8
更新日期:1988-04-01 00:00:00
abstract:BACKGROUND:Angiotensin-converting enzyme (ACE) inhibitors are established as first-line therapy in chronic heart failure (CHF). However, conflicting results exist regarding the dose-effect relation of ACE inhibitors. METHODS:We investigated 45 patients (age 55 +/- 10 years) with stable CHF who presented with a mainten...
journal_title:American heart journal
pub_type: 临床试验,杂志文章
doi:10.1016/s0002-8703(99)70179-1
更新日期:1999-10-01 00:00:00
abstract::We investigated the incidence and mechanism of pulmonary artery hypertension (PAH) in a consecutive series of patients with aortic stenosis who were undergoing diagnostic cardiac catheterization. Forty-five patients with severe aortic stenosis were divided into two groups: group 1 comprised 13 patients (29%) with PAH ...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/0002-8703(93)90067-j
更新日期:1993-01-01 00:00:00
abstract::Reperfusion therapy has lowered the mortality in patients suffering acute myocardial infarction. Failure to reperfuse is associated with significantly higher risk of short- and long-term mortality. Detection of reperfusion is thus important. In a prospective pilot study, we used continuous on-line computerized vectorc...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/0002-8703(91)90455-q
更新日期:1991-10-01 00:00:00
abstract::Previous studies have suggested that the contractility of isolated heart muscle removed from rabbits made hypercholesterolemic is decreased. As part of a study evaluating the effects of high-lipid diets on aortic atherosclerosis, we evaluated the contractility of perfused rabbit hearts. Six rabbits were placed on a hi...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/0002-8703(83)90049-2
更新日期:1983-12-01 00:00:00
abstract:BACKGROUND:The CAPTIM trial suggested a survival benefit of prehospital fibrinolysis (FL) compared to primary percutaneous coronary intervention (PCI) in patients with ST-elevation myocardial infarction (STEMI) with a presentation delay of <2 hours. We examined the relationship between reperfusion strategy and time fro...
journal_title:American heart journal
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.ahj.2010.10.033
更新日期:2011-02-01 00:00:00
abstract:BACKGROUND:ISAR-REACT was a trial designed to evaluate whether the glycoprotein IIb/IIIa inhibitor abciximab is beneficial in patients undergoing elective percutaneous coronary intervention (PCI) with stent placement after pretreatment with a 600 mg loading dose of clopidogrel. Objective for the angiographic substudy w...
journal_title:American heart journal
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.ahj.2005.08.002
更新日期:2006-06-01 00:00:00
abstract::The hemodynamic hallmark of hypertension is increased systemic vascular resistance, although this variable is usually not determined in hypertensive patients because it has generally required invasive procedures to measure cardiac output. Reliable, totally noninvasive methods are now available that measure cardiac out...
journal_title:American heart journal
pub_type: 杂志文章,评审
doi:10.1016/0002-8703(88)90565-0
更新日期:1988-08-01 00:00:00
abstract::Endocarditis is a rare manifestation of disseminated Histoplasma capsulatum infection. A 22-year-old man presented with a seven month history of fever, weight loss, and progressive aortic insufficiency. The diagnosis of H. capsulatum was suggested by a diagnostic rise in complement fixation titers and positive echocar...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/0002-8703(80)90630-4
更新日期:1980-06-01 00:00:00
abstract:BACKGROUND:Prior studies regarding the effect of racial status on post-myocardial infarction (MI) in subjects with diabetes have yielded conflicting results. We evaluated the effect of diabetes status on racial differences in post-MI mortality and morbidity for a 7-year period, from 1990 through 1997. METHODS:All pati...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/j.ahj.2005.02.042
更新日期:2005-11-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:Embolization of atherothrombotic material is common during percutaneous coronary intervention (PCI) in acute myocardial infarction (MI). This may lead to distal vessel occlusion resulting in impaired myocardial perfusion, which is associated with larger infarct size and increased mortality. Adj...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/j.ahj.2005.11.010
更新日期:2006-03-01 00:00:00
abstract::In order to properly advise cardiac patients in the regulation of their sexual activity, more basic physiologic information is needed concerning the cardiovascular effects of sexual intercourse. This study examined the effects of the male's position during sexual intercourse on heart rate and blood pressure responses....
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/s0002-8703(76)80106-8
更新日期:1976-09-01 00:00:00
abstract::There are selective blocking agents (antagonists) for alpha receptors and beta receptors. These blocking agents prevent the response to injected agonists and neurogenically released norepinephrine. The principal cardiovascular response to alpha blockade is postural hypotension with reflexly induced cardiac stimulation...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/s0002-8703(76)80020-8
更新日期:1976-12-01 00:00:00
abstract:BACKGROUND:Ibutilide is indicated for the acute termination of atrial fibrillation and atrial flutter. Recent work concludes that ibutilide activates a late inward sodium current that is blocked by nifedipine. Because calcium channel blockers are commonly used in patients with atrial fibrillation, it is important to ex...
journal_title:American heart journal
pub_type: 杂志文章,meta分析
doi:10.1067/mhj.2002.120156
更新日期:2002-01-01 00:00:00
abstract::Ventricular late potentials at the end of the surface QRS, detected on the signal-averaged electrocardiogram (SAECG) have been shown to be markers for spontaneous and/or inducible ventricular tachycardia (VT) in patients with coronary artery disease (CAD). We examined the correlations between electrophysiologic study ...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/0002-8703(88)90884-8
更新日期:1988-04-01 00:00:00
abstract::The clinical spectrum and outcome of 119 patients with acute non-Q wave myocardial infarction (NQMI) were studied, in comparison with those of 354 patients with acute Q wave myocardial infarction (QMI). The patients with NQMI had a significantly higher incidence of preinfarction angina (73% vs 63%), previous myocardia...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/0002-8703(86)90056-6
更新日期:1986-03-01 00:00:00
abstract::Although Q wave and non-Q wave MI are often referred to as "transmural" and "nontransmural," there is no anatomic evidence to justify this distinction. Nevertheless, a distinction is important, because the two entities have a different prognosis. At the present time, between 25% and 35% of MIs are non-Q wave. They are...
journal_title:American heart journal
pub_type: 杂志文章,评审
doi:10.1016/0002-8703(89)90629-7
更新日期:1989-04-01 00:00:00
abstract::The appearance of perivalvular cavities (PCs) in patients with infectious endocarditis (IE) was studied by transesophageal echocardiography (TEE) color Doppler examinations to determine whether the color Doppler TEE presentation was in keeping with the current concept of PCs representing abscesses. Two heart centers p...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/0002-8703(95)90241-4
更新日期:1995-07-01 00:00:00
abstract::Continuous-mode Doppler ultrasound and cardiac catheterization were performed within 1.4 +/- 2.0 days in 70 patients, aged 26 to 84 (mean 67 +/- 11) years, with suspected aortic stenosis. Optimal Doppler spectral display signal was recorded from the apical window in 43% of the patients, the second or third right paras...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/0002-8703(86)90694-0
更新日期:1986-07-01 00:00:00
abstract::Recently, the theory that hyperinflammation is the body's primary response to potent stimulus has been challenged. Indeed, a deregulation of the immune system could be the cause of multiple organ failure. So far, clinicians have focused on the last steps of the inflammatory cascade. However, little attention has been ...
journal_title:American heart journal
pub_type: 杂志文章,评审
doi:10.1016/j.ahj.2008.07.008
更新日期:2008-12-01 00:00:00