"Non-Q wave," alias "nontransmural," myocardial infarction: a specific entity.

Abstract:

:Although Q wave and non-Q wave MI are often referred to as "transmural" and "nontransmural," there is no anatomic evidence to justify this distinction. Nevertheless, a distinction is important, because the two entities have a different prognosis. At the present time, between 25% and 35% of MIs are non-Q wave. They are frequently observed in patients with previous coronary events. They occur in a relatively older population and involve a slightly higher proportion of women than do Q wave MIs. The degree of cardiac damage is less, reflected by a smaller rise in enzyme level and less impairment of left ventricular ejection fraction; early reperfusion may occur, after spontaneous thrombolysis or resolution of coronary spasm. The immediate mortality rate is half that of Q wave MI but identical in the long term. Reinfarction and angina are more frequent because of a peri-infarction zone of ischemia maintained by a high-grade coronary stenosis and inadequate collateral circulation. Early characterization of those MIs likely to progress is important. Diltiazem seems effective in this context if given between 24 and 72 hours of the onset of the event. Other therapeutic approaches need further assessment.

journal_name

Am Heart J

journal_title

American heart journal

authors

André-Fouet X,Pillot M,Leizorovicz A,Finet G,Gayet C,Milon H

doi

10.1016/0002-8703(89)90629-7

subject

Has Abstract

pub_date

1989-04-01 00:00:00

pages

892-902

issue

4

eissn

0002-8703

issn

1097-6744

pii

0002-8703(89)90629-7

journal_volume

117

pub_type

杂志文章,评审
  • Racial differences in endothelial function in postmenopausal women.

    abstract:OBJECTIVE:Racial differences in cardiovascular mortality among women remain largely unexplained. Preliminary data suggest that African American and Caucasian differences in endothelial function may parallel differential cardiovascular disease (CVD) risk in women. To further study differences in endothelial function bet...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/j.ahj.2004.04.032

    authors: Loehr LR,Espeland MA,Sutton-Tyrrell K,Burke GL,Crouse JR 3rd,Herrington DM

    更新日期:2004-10-01 00:00:00

  • Spironolactone-induced renal insufficiency and hyperkalemia in patients with heart failure.

    abstract:BACKGROUND:A previous randomized controlled trial evaluating the use of spironolactone in heart failure patients reported a low risk of hyperkalemia (2%) and renal insufficiency (0%). Because treatments for heart failure have changed since the benefits of spironolactone were reported, the prevalence of these complicati...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/j.ahj.2004.10.005

    authors: Tamirisa KP,Aaronson KD,Koelling TM

    更新日期:2004-12-01 00:00:00

  • R-wave amplitude responses to rapid atrial pacing: a marker for myocardial ischemia.

    abstract::Atrial pacing-induced changes in the sum of R-wave amplitude were measured in leads V5, X, Y, and Z at rates of 100 bpm (phase I), 150 bpm (phase II), and immediately after pacing (phase III) in 33 patients undergoing cardiac catheterization for evaluation of chest pain. Seventeen (51%) patients showed evidence of isc...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/0002-8703(84)90133-9

    authors: David D,Kitchen JG 3rd,Michelson EL,Naito M,Sawin HS,Chen CC

    更新日期:1984-01-01 00:00:00

  • Effects of statin therapy on progression of mild noncalcified coronary plaque assessed by serial coronary computed tomography angiography: A multicenter prospective study.

    abstract:BACKGROUND:There are limited data assessing statin therapy in patients with nonobstructive coronary plaque on coronary computed tomography angiography (CCTA). METHODS:Two hundred six consecutive patients with mild noncalcified plaque on CCTA were enrolled in this multicenter prospective observational study. Subjects w...

    journal_title:American heart journal

    pub_type: 杂志文章,多中心研究

    doi:10.1016/j.ahj.2016.06.023

    authors: Li Z,Hou Z,Yin W,Liu K,Gao Y,Xu H,Yu F,Ma Z,Yu W,Yang L,Lu B

    更新日期:2016-10-01 00:00:00

  • Transdermal clonidine as an adjunct to nifedipine-GITS therapy in patients with mild-to-moderate hypertension.

    abstract::Calcium channel blockers and central alpha-agonists are among the classes of antihypertensive drugs that yield the most favorable overall effects on risk factors for hypertension-related end-organ damage. An open-label prospective trial in 42 patients with a mean baseline blood pressure of 144/102 mm Hg sought to asse...

    journal_title:American heart journal

    pub_type: 临床试验,杂志文章

    doi:10.1016/0002-8703(93)90707-g

    authors: Houston MC,Hays L

    更新日期:1993-10-01 00:00:00

  • Hemodynamic evaluation of the Ionescu-Shiley pericardial xenograft in the mitral position.

    abstract::Hemodynamic studies were performed in 27 patients at a mean interval of 40.3 (range 24 to 59) months following mitral valve replacement with pericardial xenografts. Six patients had sequential studies, one before operation and two separate investigations at mean intervals of 11.2 and 42.8 months following valve replac...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/0002-8703(78)90301-0

    authors: Tandon AP,Smith DR,Ionescu MI

    更新日期:1978-05-01 00:00:00

  • Diabetic angiopathy--its lessons in vascular physiology.

    abstract::Progress in our understanding diabetic angiopathy has been slow, but we are now learning a number of lessons of interest to the cardiologist. Diabetic angiopathy is a collective term for conditions specific to the diabetic state and related to its duration more than to patient age. The angiopathy produces calcificatio...

    journal_title:American heart journal

    pub_type: 杂志文章,评审

    doi:10.1016/0002-8703(78)90053-4

    authors: McMillan DE

    更新日期:1978-09-01 00:00:00

  • Antithrombotic therapy in left ventricular thrombosis and systemic embolism.

    abstract::Left ventricular (LV) thrombi are responsible for significant morbidity and mortality in our society. Twenty-five percent of cardiogenic emboli are associated with acute and chronic myocardial infarction. With the development of noninvasive imaging techniques LV thrombi have been increasingly recognized as an importan...

    journal_title:American heart journal

    pub_type: 杂志文章,评审

    doi:10.1016/0002-8703(92)91069-d

    authors: Cregler LL

    更新日期:1992-04-01 00:00:00

  • The electrophysiologic characteristics of the transplanted human heart.

    abstract::The electrophysiologic characteristics of the denervated human heart were assessed in 14 cardiac transplant recipients. Conduction intervals and refractory periods were measured at pacing cycle lengths of 500 msec and 400 msec. The faster pacing rate caused lengthening of the AH interval (83 +/- 23 msec to 116 +/- 41 ...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/0002-8703(84)90124-8

    authors: Bexton RS,Nathan AW,Hellestrand KJ,Cory-Pearce R,Spurrell RA,English TA,Camm AJ

    更新日期:1984-01-01 00:00:00

  • Rational and design of a randomized, double-blind, multicenter trial to evaluate the safety and tolerability of furosemide withdrawal in stable chronic outpatients with heart failure: The ReBIC-1 trial.

    abstract:AIMS:Furosemide is commonly prescribed for symptom relief in heart failure (HF) patients. Although few data support the continuous use of loop diuretics in apparently euvolemic HF patients with mild symptoms, there is concern about safety of diuretic withdrawal in these patients. The ReBIC-1 trial was designed to evalu...

    journal_title:American heart journal

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1016/j.ahj.2017.08.012

    authors: da Rosa PR,Rohde LE,Doebber M,Ribeiro ALP,Prado DP,Bertoldi EG,Figueiredo Neto JA,Kohler I,Beck-da-Silva L,Danzmann LC,Moura LZ,Rover M,Simões MV,Sant'Anna RT,Biolo A

    更新日期:2017-12-01 00:00:00

  • Blood pressure control and hormone replacement therapy in postmenopausal women at risk for coronary heart disease.

    abstract:BACKGROUND:Coronary heart disease (CHD) in women is strongly associated with estrogen deprivation. For example, risk for CHD increases dramatically after menopause. However, the role of hormone replacement therapy (HRT) in CHD prevention currently is unresolved. To better understand CHD in women, the precise mechanisms...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1067/mhj.2002.121262

    authors: McCubbin JA,Helfer SG,Switzer FS 3rd,Price TM

    更新日期:2002-04-01 00:00:00

  • Sinus node recovery times following the spontaneous termination of supraventricular tachycardia and following atrial overdrive pacing: a comparison.

    abstract::We compared the pauses that followed the spontaneous termination of supraventricular tachyarrhythmias with the pauses that followed the cessation of atrial overdrive pacing in 21 patients. In 10 patients with abnormal sinus node function and in 11 patients with normal sinus node function we recorded the spontaneous te...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/0002-8703(83)90515-x

    authors: Gang ES,Reiffel JA,Livelli FD Jr,Bigger JT Jr

    更新日期:1983-02-01 00:00:00

  • Underlying risk factors incrementally add to the standard risk estimate in detecting subclinical atherosclerosis in low- and intermediate-risk middle-aged asymptomatic individuals.

    abstract:BACKGROUND:Traditional risk factors predict the 10-year risk of developing coronary heart disease (CHD). Underlying risk factors like physical inactivity, obesity (BMI >30 kg/m2), and family history of premature CHD are independently associated with CHD. High burden of coronary artery calcification (CAC) on electron be...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/j.ahj.2004.05.033

    authors: Desai MY,Nasir K,Braunstein JB,Rumberger JA,Post WS,Budoff MJ,Blumenthal RS

    更新日期:2004-11-01 00:00:00

  • Role of intracellular calcium in the antiarrhythmic effect of procainamide during ventricular fibrillation in rat hearts.

    abstract::Increased intracellular calcium (calcium overload) is considered one of the factors that can initiate ventricular fibrillation. In addition, ventricular fibrillation itself can cause and possibly maintain calcium overload. The goal of this study was to determine whether the class IA antiarrhythmic agent procainamide c...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/0002-8703(95)90453-0

    authors: Zaugg CE,Wu ST,Kojima S,Wikman-Coffelt J,Parmley WW,Buser PT

    更新日期:1995-08-01 00:00:00

  • Relation between cardiac troponin I and mortality in acute decompensated heart failure.

    abstract:BACKGROUND:Troponin level elevations are common in patients with acute decompensated heart failure (ADHF), yet their prognostic value above and beyond traditional predictors of outcomes in heart failure is uncertain. METHODS:In the EFFECT study, we determined the association between cardiac troponin I and all-cause mo...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/j.ahj.2007.01.027

    authors: You JJ,Austin PC,Alter DA,Ko DT,Tu JV

    更新日期:2007-04-01 00:00:00

  • Angina symptoms in men and women with stable coronary artery disease and evidence of exercise-induced myocardial perfusion defects.

    abstract:BACKGROUND:To examine sex differences in pain and associated symptoms in patients with exercise-related ischemia, as well as the independence of these findings from other clinical factors. METHODS:Prospective study of 482 women and 425 men (mean age 58 years) undergoing exercise stress testing with myocardial perfusio...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/j.ahj.2005.06.028

    authors: D'Antono B,Dupuis G,Fortin C,Arsenault A,Burelle D

    更新日期:2006-04-01 00:00:00

  • Beneficial effects of the alpha-adrenergic antagonist nicergoline during acute myocardial ischemia and reperfusion in the dog.

    abstract::Recent experimental and clinical data have stimulated interest in the use of alpha-adrenergic antagonists in acute myocardial infarction. We evaluated nicergoline, a new relatively selective alpha 1-antagonist which uniquely lowers heart rate. Open-chest dogs, randomized to control (n = 25) or intravenously treated gr...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/0002-8703(83)90646-4

    authors: Bolli R,Brandon TA,Fisher DJ,Fernandez GC,Miller RR

    更新日期:1983-11-01 00:00:00

  • Effect of delay on racial differences in thrombolysis for acute myocardial infarction.

    abstract:OBJECTIVE:To analyze the effect of delay times on racial differences in thrombolysis for acute myocardial infarction. BACKGROUND:Lower rates of thrombolytic therapy in blacks with acute myocardial infarction have recently been reported, but the reasons for this disparity are unknown. We hypothesized that lower rates o...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1067/mhj.2000.109644

    authors: Syed M,Khaja F,Rybicki BA,Wulbrecht N,Alam M,Sabbah HN,Goldstein S,Borzak S

    更新日期:2000-10-01 00:00:00

  • Relationship between initial white blood cell counts, stage of acute myocardial infarction evolution at presentation, and incidence of Thrombolysis In Myocardial Infarction-3 flow after streptokinase.

    abstract:BACKGROUND:The initial white cell counts in patients with acute myocardial infarction (AMI) may reflect the stage of AMI evolution, and may also be related to the efficacy of thrombolytic agents in recanalizing occluded epicardial arteries. METHODS:In 312 patients with a first AMI, we divided the initial white cell co...

    journal_title:American heart journal

    pub_type: 临床试验,杂志文章

    doi:10.1067/mhj.2003.64

    authors: Wong CK,French JK,Gao W,White HD

    更新日期:2003-01-01 00:00:00

  • Adaptation to myocardial ischemia during coronary angioplasty demonstrated by clinical, electrocardiographic, echocardiographic, and metabolic parameters.

    abstract::It has been shown that brief episodes of myocardial ischemia can render the heart more resistant to a prolonged subsequent ischemic episode. This phenomenon, called "preconditioning," has been described in human beings during coronary angioplasty with the use of clinical, electrocardiographic (ECG), or metabolic param...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/s0002-8703(97)70200-x

    authors: Eltchaninoff H,Cribier A,Tron C,Derumeaux G,Koning R,Hecketsweiller B,Letac B

    更新日期:1997-04-01 00:00:00

  • Interactions of wine drinking with omega-3 fatty acids in patients with coronary heart disease: a fish-like effect of moderate wine drinking.

    abstract:BACKGROUND:Moderate alcohol drinking and marine omega-3 fatty acids (omega3) have both been associated with low mortality from coronary heart disease (CHD). However, there is little data evaluating the interactions of wine ethanol drinking with omega3 in CHD patients. METHODS:The relationships between wine drinking an...

    journal_title:American heart journal

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.ahj.2007.08.009

    authors: de Lorgeril M,Salen P,Martin JL,Boucher F,de Leiris J

    更新日期:2008-01-01 00:00:00

  • Randomized coronary patency trial of double-bolus recombinant staphylokinase versus front-loaded alteplase in acute myocardial infarction.

    abstract::One hundred two patients with evolving myocardial infarction of 6 hours' duration were given aspirin and intravenous heparin and randomly allocated to intravenous front-loaded, weight-adjusted rTPA administration over a 90-minute period (52 patients) or to two 15 mg doses of recombinant staphylokinase, 30 minutes apar...

    journal_title:American heart journal

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验

    doi:10.1016/s0002-8703(97)70127-3

    authors: Vanderschueren S,Dens J,Kerdsinchai P,Desmet W,Vrolix M,De Man F,Van den Heuvel P,Hermans L,Collen D,Van de Werf F

    更新日期:1997-08-01 00:00:00

  • Low-molecular-weight heparin versus unfractionated heparin in acute ST-segment elevation myocardial infarction patients undergoing primary percutaneous coronary intervention with drug-eluting stents.

    abstract:BACKGROUND:Whether low-molecular-weight heparin (LMWH) is superior to unfractionated heparin (UFH) in acute ST-segment elevation myocardial infarction (STEMI) patients undergoing primary percutaneous coronary intervention (PCI) with drug-eluting stents (DESs) remains unclear. METHODS:A total of 3,372 STEMI patients wh...

    journal_title:American heart journal

    pub_type: 临床试验,杂志文章,多中心研究

    doi:10.1016/j.ahj.2009.12.041

    authors: Li YJ,Rha SW,Chen KY,Poddar KL,Jin Z,Minami Y,Wang L,Dang Q,Li GP,Ramasamy S,Park JY,Choi CU,Kim JW,Kim EJ,Park CG,Seo HS,Oh DJ,Jeong MH,Ahn YK,Hong TJ,Park JS,Kim YJ,Hur SH,Seong IW,Chae JK,Cho MC,Bae

    更新日期:2010-04-01 00:00:00

  • Beta-adrenergic blockade by nadolol in control of ventricular tachyarrhythmias.

    abstract::The antiarrhythmic effect of nadolol, a long-acting, nonselective beta antagonist without intrinsic sympathomimetic or membrane-stabilizing properties, was evaluated in 36 patients with ventricular dysrhythmias as determined by three baseline 24-hour Holter recordings at a time when subjects were receiving placebo. Na...

    journal_title:American heart journal

    pub_type: 临床试验,杂志文章

    doi:10.1016/0002-8703(84)90590-8

    authors: Nademanee K,Schleman MM,Singh BN,Morganroth J,Reid PR,Stritar JA

    更新日期:1984-10-01 00:00:00

  • Comparison of 3- versus 6-minute infusions of adenosine in thallium-201 myocardial perfusion imaging.

    abstract::Adenosine thallium stress testing has a demonstrated utility in the detection of coronary artery disease. The optimal dose for diagnostic efficacy with minimal side effects has not been critically evaluated. A randomized 3- and 6-minute infusion of adenosine (140 micrograms/kg/min) was performed in 11 subjects. Subjec...

    journal_title:American heart journal

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1016/s0002-8703(07)80015-9

    authors: Villegas BJ,Hendel RC,Dahlberg ST,McSherry BA,Leppo JA

    更新日期:1993-07-01 00:00:00

  • Sudden cardiac death: the role of risk stratification.

    abstract::Sudden cardiac death syndrome remains a major health problem responsible for approximately 400,000 deaths annually in the US. Effective therapies exist but are costly and are associated with potential complications. Currently used strategies for selection of the best candidates for implantable cardioverter defibrillat...

    journal_title:American heart journal

    pub_type: 杂志文章,评审

    doi:10.1016/j.ahj.2007.01.024

    authors: Kusmirek SL,Gold MR

    更新日期:2007-04-01 00:00:00

  • Giant cell (cranial) arteritis: a clinical review.

    abstract::Giant cell arteritis is a disease of the elderly which is more common than previously recognized. It is important to be aware of this condition because treatment effectively relieves symptoms and prevents serious complications. The disease is suggested when an elderly patient complains of constitutional symptoms, head...

    journal_title:American heart journal

    pub_type: 杂志文章,评审

    doi:10.1016/0002-8703(80)90285-9

    authors: Huston KA,Hunder GG

    更新日期:1980-07-01 00:00:00

  • Sustained-release local hirulog therapy decreases early thrombosis but not neointimal thickening after arterial stenting.

    abstract::Adventitial heparin delivery has been shown to inhibit thrombosis and neointimal thickening in a rat carotid injury model. To determine whether sustained, local delivery of hirulog, a potent antithrombin agent, inhibits thrombus formation and neointimal thickening after arterial stenting, silicone polymers containing ...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/s0002-8703(96)90343-9

    authors: Muller DW,Gordon D,Topol EJ,Levy RJ,Golomb G

    更新日期:1996-02-01 00:00:00

  • Trends in the pharmacologic management of atrial fibrillation: Data from the Veterans Affairs health system.

    abstract:BACKGROUND:Prescribing rate control medications with or without antiarrhythmic drugs is often the first course treatment for atrial fibrillation (AF). Clinical trial data suggest that antiarrhythmic drugs are only marginally effective and have multiple drawbacks, whereas rate control alone is sufficient for most patien...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/j.ahj.2014.03.024

    authors: Vaughan-Sarrazin MS,Mazur A,Chrischilles E,Cram P

    更新日期:2014-07-01 00:00:00

  • Repeat coronary angioplasty during the same angiographic diagnosis of coronary restenosis.

    abstract::To determine whether any differences exist in results of treatment of restenosis with repeat angioplasty when the procedure is performed during diagnosis or, as an alternative, when it is performed as a separate elective procedure, we prospectively compared the outcome of 48 consecutive procedures (including 51 lesion...

    journal_title:American heart journal

    pub_type: 杂志文章

    doi:10.1016/s0002-8703(05)80010-9

    authors: Alfonso F,Macaya C,Iñiguez A,Zarco P

    更新日期:1990-02-01 00:00:00