Circulating antibodies to the 60-kD heat shock protein (hsp) family in patients with Helicobacter pylori infection.

abstract：:Perforin, one of the cytotoxic proteins of the immune system, plays a prominent role in protection against viral and bacterial infections. We investigated its expression in PBL and their CD3+, CD4+, CD8+ and CD16+ and/or CD56+ subpopulations in endurance athletes before and after a triathlon. Lymphocyte subpopulations...

journal_title：Clinical and experimental immunology

authors： Staats R,Balkow S,Sorichter S,Northoff H,Matthys H,Luttmann W,Berg A,Virchow JC

更新日期：2000-06-01 00:00:00

abstract：:Sjögren's syndrome (SS) is a chronic autoimmune disease that mainly damages the salivary and lacrimal glands. Immune complex (IC) formation triggers local inflammation through IC deposition and decreased antigen function. Some ICs can leak from the lesion and into the saliva but no salivary ICs have been reported to d...

journal_title：Clinical and experimental immunology

authors： Yamane K,Nakamura H,Hamasaki M,Minei Y,Aibara N,Shimizu T,Kawakami A,Nakashima M,Kuroda N,Ohyama K

更新日期：2021-01-12 00:00:00

abstract：:The guinea pig model of low-dose pulmonary tuberculosis has been used to study the pathogenesis of infection as well as the mechanisms of bacille Calmette-Guérin (BCG) vaccine-induced resistance. We investigated the function of lung cells from naive and BCG-vaccinated guinea pigs after enzymatic digestion of lung tiss...

journal_title：Clinical and experimental immunology

authors： Jeevan A,Majorov K,Sawant K,Cho H,McMurray DN

更新日期：2007-08-01 00:00:00

abstract：:Amyloid A (AA) amyloidosis is characterized by extracellular pathogenic deposition of insoluble fibril protein in various body organs. Deposited amyloid generally remains in a variety of organs for long periods, but its disappearance has been reported after the precursor protein is diminished. The kinetics of AA depos...

journal_title：Clinical and experimental immunology

authors： Muhammad N,Murakami T,Inoshima Y,Ishiguro N

更新日期：2015-07-01 00:00:00

abstract：:Booster immunization of normal individuals with soluble tetanus toxoid (TT) produced significant levels of plasma anti-tetanus IgG and IgM detectable by an enzyme linked immunosorbent assay (ELISA). Similar changes in circulating anti-TT antibody were found in mice following primary immunization. There was. however, n...

journal_title：Clinical and experimental immunology

authors： Ershler WB,Moore AL,Hacker MP

更新日期：1982-09-01 00:00:00

abstract：:Type I diabetes (T1D) is a T cell-mediated autoimmune disease characterized by loss of tolerance to islet autoantigens, leading to the destruction of insulin-producing beta cells. Peripheral tolerance to self is maintained in health through several regulatory mechanisms, including a population of CD4+CD25hi naturally ...

journal_title：Clinical and experimental immunology

authors： Lawson JM,Tremble J,Dayan C,Beyan H,Leslie RD,Peakman M,Tree TI

更新日期：2008-12-01 00:00:00

abstract：:CD44 is an adhesion molecule involved in a wide range of cell-cell and cell-matrix interactions. The standard form of CD44 (CD44S) is a 85-90-kD glycoprotein, but alternative splicing of RNA encoding 10 variable exons (V1-V10) can give rise to many different CD44 variant protein isoforms of higher molecular weight. CD...

journal_title：Clinical and experimental immunology

authors： Takazoe K,Foti R,Tesch GH,Hurst LA,Lan HY,Atkins RC,Nikolic-Paterson DJ

更新日期：2000-09-01 00:00:00

abstract：:The present study reports a rare case of systemic M. scrofulaceum infection in an AIDS patient and analyses the inflammatory infiltrate in a lymph node by immunohistochemistry. Special emphasis is put on the histiocytes. The diffuse infiltrate consists mainly of large histiocytes that contain numerous bacilli. These c...

journal_title：Clinical and experimental immunology

authors： Delabie J,De Wolf-Peeters C,Bobbaers H,Bilbe G,Desmet VJ

更新日期：1991-08-01 00:00:00

abstract：:Ultrastructural study of mucosal eosinophils in a case of eosinophilic gastroenteritis involving stomach, duodenum and ileum showed an altered structure in ulcerated duodenal areas. The electron core density of eosinophil granules was inverted or disappeared and tubulovesicular structures occurred. Using immunogold st...

journal_title：Clinical and experimental immunology

authors： Torpier G,Colombel JF,Mathieu-Chandelier C,Capron M,Dessaint JP,Cortot A,Paris JC,Capron A

更新日期：1988-12-01 00:00:00

abstract：:Systemic capillary leak syndrome (SCLS) is a rare disease characterized by episodes of collapse due to rapid transfer of considerable volumes of plasma from the intravascular to the extravascular compartment. The pathogenesis of this disease is unknown. The diagnosis is made largely on clinical grounds, and investigat...

journal_title：Clinical and experimental immunology

authors： Zhang W,Ewan PW,Lachmann PJ

更新日期：1993-09-01 00:00:00

abstract：:Rheumatoid arthritis (RA), seronegative spondyloarthropathy (SA) and osteoarthritis (OA) patients receiving no steroid or disease-modifying therapy have been monitored, along with healthy controls, for their prevailing level of Epstein-Barr virus (EBV) infection using four independent indices of the EBV-host balance, ...

journal_title：Clinical and experimental immunology

authors： Yao QY,Rickinson AB,Gaston JS,Epstein MA

更新日期：1986-05-01 00:00:00

abstract：:Recent evidence has shown that microRNA-126 (miR-126) has been involved in the development and function of immune cells, which contributed to the pathogenesis of related clinical diseases. However, the potential role of miR-126 in the development and function of CD4+ T cells remains largely unknown. Here we first foun...

journal_title：Clinical and experimental immunology

authors： Chu F,Hu Y,Zhou Y,Guo M,Lu J,Zheng W,Xu H,Zhao J,Xu L

更新日期：2018-02-01 00:00:00

abstract：:Data from a previous study suggested that peripheral blood monocytes in patients with rheumatoid arthritis (RA) may be activated. Therefore, in this study we sought further evidence of 'presynovial' activation of monocytes. Our results show that phenotypic changes are demonstrable in peripheral blood monocytes in pati...

journal_title：Clinical and experimental immunology

authors： Highton J,Carlisle B,Palmer DG

更新日期：1995-12-01 00:00:00

abstract：:T helper type 17 (Th17) cells play a pathogenic role in autoimmune disease, while interleukin (IL)-10-producing Th10 cells serve a protective role. The balance between the two subsets is regulated by the local cytokine milieu and by the relative expression of intact forkhead box protein 3 (FoxP3) compared to FoxP3Δ2, ...

journal_title：Clinical and experimental immunology

authors： Kristensen B,Hegedüs L,Madsen HO,Smith TJ,Nielsen CH

更新日期：2015-04-01 00:00:00

abstract：:In this paper we report studies undertaken to determine the contribution of seminal prostaglandins to some of the known immunosuppressive properties of human seminal plasma. Initial studies revealed that fractions of seminal plasma enriched in E series prostaglandins, obtained by reverse phase chromatography, had a pr...

journal_title：Clinical and experimental immunology

authors： Quayle AJ,Kelly RW,Hargreave TB,James K

更新日期：1989-03-01 00:00:00

abstract：:The respective roles of thymus-derived and bone marrow-derived lymphocytes in the immune response to DNA was investigated in mice reconstituted with various cell populations using cell transfers. A helper effect of thymus-derived cells in the immune response to DNA was suggested by experiments performed in athymic nud...

journal_title：Clinical and experimental immunology

authors： Fournié GJ,Lambert PH,Bankhurst AD,Miescher PA

更新日期：1976-10-01 00:00:00

abstract：:Asthma is a chronic inflammatory disease affecting the airways. Increased levels of T cells are found in the lungs after the induction of an allergic-like inflammation in rats, and flow cytometry studies have shown that these levels are reduced in CD26-deficient rats. However, the precise anatomical sites where these ...

journal_title：Clinical and experimental immunology

authors： Schade J,Schmiedl A,Kehlen A,Veres TZ,Stephan M,Pabst R,von Hörsten S

更新日期：2009-10-01 00:00:00

abstract：:The relation of clinical and laboratory findings at the time clinical presentation to subsequent survival was investigated in 204 patients with macroglobulinaemia. It was found that the ten following clinical and laboratory parameters were of prognostic significance and a further twelve were not. The best prognoses we...

journal_title：Clinical and experimental immunology

authors： Carter P,Koval JJ,Hobbs JR

更新日期：1977-05-01 00:00:00

abstract：:The X-linked lymphoproliferative syndrome (XLPS) is an immunodeficiency characterized by severe primary infection with the Epstein Barr (EB) virus, which is often fatal. This has been attributed to failure to generate T lymphocytes which are specifically cytotoxic for EB virus-infected B lymphocytes, and which develop...

journal_title：Clinical and experimental immunology

authors： Ando I,Morgan G,Levinsky RJ,Crawford DH

更新日期：1986-02-01 00:00:00

abstract：:Depletion of monocytes from peripheral blood mononuclear cells of patients with systemic lupus erythematosus (SLE) resulted in a decreased anti-DNA antibody synthesis in vitro. The addition of monocytes restored the response by lymphocytes and the maximum response in the presence of 2.5-8% of monocytes, whereas greate...

journal_title：Clinical and experimental immunology

authors： Sasaki T,Shibata S,Hirabayashi Y,Sekiguchi Y,Yoshinaga K

更新日期：1989-07-01 00:00:00

abstract：:Elevation of intracellular cAMP levels has been shown previously to inhibit cytokine secretion by various cell types in vitro. Since salmeterol is a beta 2-agonist which activates adenylate cyclase, its ability to inhibit cytokine production was evaluated. Though salmeterol, and the related drug albuterol, did not inh...

journal_title：Clinical and experimental immunology

authors： Sekut L,Champion BR,Page K,Menius JA Jr,Connolly KM

更新日期：1995-03-01 00:00:00

abstract：:Nine patients with active systemic lupus erythematosus entered a double-blind randomized trial to study the therapeutic effect of vigorous versus sham reinfusion plasmapheresis. Four of them received real plasmapheresis while five received sham reinfusion plasmapheresis. In the present communication we report the effe...

journal_title：Clinical and experimental immunology

authors： Tsokos GC,Balow JE,Huston DP,Wei N,Decker JL

更新日期：1982-05-01 00:00:00

abstract：:Kawasaki disease (KD) is an immune-mediated vasculitis with symptoms that mimic febrile illness; the immune origin has been suggested but never proved. First, cell chip technology was used to screen immune targets cells. With the indirect immunofluorescence assay we found that the HeLa cell chip could be recognized by...

journal_title：Clinical and experimental immunology

authors： Cui J,Zhou Y,Hu H,Zhao L,Du Z,Du H

更新日期：2018-12-01 00:00:00

abstract：:Although Mycobacterium leprae shares many protein antigens with other mycobacterial species, there is a degree of specificity in the T cell response to the organism. This is evident in the failure of cross-protection between mycobacterial species and the specific unresponsiveness to M. leprae in lepromatous leprosy pa...

journal_title：Clinical and experimental immunology

authors： Adams E,Basten A,Prestidge R,Britton WJ

更新日期：1995-10-01 00:00:00

abstract：:The effects of various cytokines on synthesis and microheterogeneity of carbohydrate structure of alpha 1-proteinase inhibitor (PI) and alpha-fetoprotein (AFP) in the human hepatoma cell lines Hep 3B and Hep G2 were studied. In both lines, crude cytokine preparations from LPS-activated human monocytes (CM) and several...

journal_title：Clinical and experimental immunology

authors： Mackiewicz A,Schultz D,Mathison J,Ganapathi M,Kushner I

更新日期：1989-01-01 00:00:00

abstract：:Rheumatoid arthritis (RA) is a chronic inflammatory disease characterized by synovial fibroblast hyperplasia and bone erosion. Fibroblast-like synoviocytes (FLS) play a pivotal role in RA pathogenesis through aggressive migration and matrix invasion, and certain proinflammatory cytokines may affect synoviocyte invasio...

journal_title：Clinical and experimental immunology

authors： Xing R,Jin Y,Sun L,Yang L,Li C,Li Z,Liu X,Zhao J

更新日期：2016-05-01 00:00:00

abstract：:Clustering activity for neutrophil granulocytes was generated in pooled normal human serum (NHS) by incubation of the serum with preformed IgG aggregates, but not in heat-treated NHS (56 degrees C, 30 min), indicating that the function was complement-dependent. Judging from results of experiments with complement-defic...

journal_title：Clinical and experimental immunology

authors： Sturfelt G,Jonsson H,Hellmer G,Sjöholm AG

更新日期：1993-08-01 00:00:00

abstract：:Diagnosis of perinatal infection in the newborn is difficult; there may be few clinical signs and current tests are slow or non-specific. Detection of organisms, antigen or specific antibody to common pathogens often requires repeat samples and does not give immediate results. Haematological parameters, although relie...

journal_title：Clinical and experimental immunology

authors： Hodge S,Hodge G,Flower R,Han P

更新日期：1998-07-01 00:00:00

abstract：:Enterohaemorrhagic Escherichia coli (EHEC) O157:H7 infections are considered a public health problem in both developed and developing countries because of their increasing incidence and the severity of clinical presentation. Approximately 10% of infected patients develop complications such as haemolytic uraemic syndro...

journal_title：Clinical and experimental immunology

authors： Brando RJ,Miliwebsky E,Bentancor L,Deza N,Baschkier A,Ramos MV,Fernández GC,Meiss R,Rivas M,Palermo MS

更新日期：2008-08-01 00:00:00

abstract：:Parechymal cells (PC) were prepared by digestion of perfused, lavaged rat lung in a mixture of collagenase and DNase, and harvested on a discontinuous percoll gradient. The process yielded on average 1.0 X 10(8) viable cells/gram tissue. PC were pulsed with soluble antigen, and tested for their capacity to trigger ant...

journal_title：Clinical and experimental immunology

authors： Holt PG,Degebrodt A,O'Leary C,Krska K,Plozza T

更新日期：1985-12-01 00:00:00