Contributions of hypoxia and respiratory disturbance index to sympathetic activation and blood pressure in obstructive sleep apnea syndrome.

abstract：OBJECTIVES:Central blood pressure (BP) can be used to define hypertension. A central BP approach may be more sensitive than a conventional brachial BP approach in detecting hypertension. We aimed to compare the 2 approaches in estimating the prevalence hypertension in a nationally representative population. METHODS:A ...

journal_title：American journal of hypertension

authors： Chuang SY,Chang HY,Cheng HM,Pan WH,Chen CH

更新日期：2018-02-09 00:00:00

abstract：:Components of the kallikrein kinin system have been associated with the pathophysiology of hypertension in animal and human studies. In this study, we examined the distribution of four different polymorphisms of the kinin B1 and B2 receptor genes in a population of 120 normotensive and 77 hypertensive African-American...

journal_title：American journal of hypertension

authors： Gainer JV,Brown NJ,Bachvarova M,Bastien L,Maltais I,Marceau F,Bachvarov DR

更新日期：2000-12-01 00:00:00

abstract：:To study potential ionic factors predisposing to vascular disease in hypertension, particularly among black subjects, we used a recently developed combined magnesium and calcium specific, ion selective electrode apparatus to measure extracellular ionized calcium (Ca-ion), ionized magnesium (Mg-ion), and Ca-ion/Mg-ion ...

journal_title：American journal of hypertension

authors： Resnick LM,Bardicef O,Altura BT,Alderman MH,Altura BM

更新日期：1997-12-01 00:00:00

abstract：:Managing hypertension is a complex undertaking, where even the definition of the disorder is subject to discussion. Recently, there has been controversy concerning the most appropriate measure to determine health risks associated with hypertension. In the past, diastolic blood pressure (DBP) was the prime measure for ...

journal_title：American journal of hypertension

authors： Cushman WC

更新日期：2001-07-01 00:00:00

abstract：BACKGROUND:Higher fibroblast growth factor-23 (FGF23) concentrations have been found to be associated with incident heart failure (HF). Experimental data suggest FGF23 directly stimulates myocardial hypertrophy. FGF23 may also enhance renin-angiotensin-aldosterone system activity. Whether FGF23 is associated with incre...

journal_title：American journal of hypertension

authors： Akhabue E,Vu TT,Vaidya A,Michos ED,de Boer IH,Kestenbaum B,Allison M,Szklo M,Ouyang P,Yancy CW,Wolf M,Isakova T,Carnethon MR

更新日期：2019-01-01 00:00:00

abstract：:Post-transplant hypertension remains an important risk factor for cardiovascular mortality and graft function. There are multiple mechanisms responsible for post-transplant hypertension. The details of these mechanisms are poorly understood. Steroids, acute and chronic rejection, recurrent renal disease, native kidney...

journal_title：American journal of hypertension

authors： Laskow DA,Curtis JJ

更新日期：1990-09-01 00:00:00

abstract：:The effects of angiotensin converting enzyme (ACE) inhibitors on the release of angiotensin II (Ang II) from isolated mesenteric arteries of spontaneously hypertensive rats (SHRs) were examined. Delapril, enalapril, and captopril suppressed Ang II release in a dose-dependent manner. After oral treatment with delapril ...

journal_title：American journal of hypertension

authors： Higashimori K,Nakamaru M,Tabuchi Y,Nagano M,Mikami H,Ogihara T,Inagami T

更新日期：1991-01-01 00:00:00

abstract：:To clarify the function of polymorphonuclear leukocytes (PMN) in spontaneously hypertensive rats (SHR) and the effect of beraprost sodium (BS) on these functions, we examined superoxide anion (O2-) production and adherent activity by PMN, as well as modification of these functions by BS ex vivo and in vitro. In study ...

journal_title：American journal of hypertension

authors： Ohmori M,Kitoh Y,Kawaguchi A,Harada K,Sugimoto K,Fujimura A

更新日期：2001-07-01 00:00:00

abstract：:Cultured vascular smooth muscle cells (VSMCs) of the spontaneously hypertensive rat (SHR) show a higher density (Bmax) of ANP receptors and a blunted cyclic (c) GMP response to the hormone. To explore the idea that a higher cytosolic free Ca2+ (Cai2+) may be responsible for a blunted cGMP response to ANP, we examined ...

journal_title：American journal of hypertension

authors： Nakamura M,Nakamura A,Hatori N,Fine BP,Aviv A

更新日期：1989-02-01 00:00:00

abstract：:Left ventricular hypertrophy (LVH) has been identified as one of the strongest blood pressure-independent risk factors for sudden death, acute myocardial infarction, congestive heart failure, and other cardiovascular morbidity and mortality. Hypertensive patients with LVH have a significantly greater prevalence of pre...

journal_title：American journal of hypertension

authors： Messerli FH

更新日期：1999-12-01 00:00:00

abstract：:The goal of this study was to investigate the activity of the Na+/H+ exchanger in erythrocytes of patients with essential hypertension and its relation with urinary Na+ excretion. The study was performed in cells from 27 untreated hypertensive patients and 30 normotensive controls with similar age and sex distribution...

journal_title：American journal of hypertension

authors： Díez J,Alonso A,Garciandía A,López R,Gómez-Alamillo C,Arrázola A,Fortuño A

更新日期：1995-02-01 00:00:00

abstract：BACKGROUND:The present study examined the inhibitory action of temporary treatment with an angiotensin type 1 (AT(1)) receptor blocker (ARB) on vascular remodeling using hypertensive mice with overexpression of the human renin (hRN) and angiotensinogen (hANG) genes. METHODS:hRN/hANG transgenic mice (hRN/hANG-Tg) were ...

journal_title：American journal of hypertension

authors： Inaba S,Iwai M,Furuno M,Kanno H,Senba I,Okayama H,Mogi M,Higaki J,Horiuchi M

更新日期：2011-05-01 00:00:00

abstract：:Renin secretion by the kidney is inhibited by an increase in free intracellular calcium concentration. This increase in free intracellular calcium content may be augmented by serum 1,25-dihydroxyvitamin D. In 10 subjects with high renin hypertension, an increase in dietary sodium intake resulted in an increase in urin...

journal_title：American journal of hypertension

authors： Burgess ED,Hawkins RG,Watanabe M

更新日期：1990-12-01 00:00:00

abstract：:Despite intense investigation and clinical attention, many challenges remain in the management of the hypertensive patient. It is clear that hypertension remains inadequately controlled worldwide, with the control rate in the United States approximating 27%. Furthermore, several recent studies have underscored that it...

journal_title：American journal of hypertension

authors： Epstein M

更新日期：2002-07-01 00:00:00

abstract：:Alterations in Na, K ATPase pump activity as well as erythrocyte (RBC) intracellular sodium concentration (Nai) have been demonstrated in humans and rats with established hypertension. The contribution of hypertension itself to these changes is unclear. Accordingly, we investigated RBC ion transport and plasma ouabain...

journal_title：American journal of hypertension

authors： McCormick CP,Hennessy JF,Rauch AL,Buckalew VM Jr

更新日期：1989-08-01 00:00:00

abstract：BACKGROUND:Our aim was to assess whether home blood pressure (HBP) and ambulatory BP monitoring measurement (ABPM), in addition to office BP (OBP) predict changes of cardiovascular biomarkers during antihypertensive treatment. METHODS:Two hundred and fifty-two hypertensive patients (mean age, 68 years; men: 41%) under...

journal_title：American journal of hypertension

authors： Yano Y,Hoshide S,Shimizu M,Eguchi K,Ishikawa J,Ishikawa S,Shimada K,Kario K

更新日期：2012-03-01 00:00:00

abstract：BACKGROUND:Carvedilol is known to be an adrenoreceptor blocker and free radical scavenger, used in hypertension and cardiac failure. However, its therapeutic actions cannot be fully explained by these mechanisms. In these studies, we tested the hypothesis that carvedilol action is associated with the synthesis/release ...

journal_title：American journal of hypertension

authors： Afonso RA,Patarrao RS,Macedo MP,Carmo MM

更新日期：2006-04-01 00:00:00

abstract：:In order to further characterize previously described racial differences in intracellular Ca2+ homeostasis, the activity of sarcoplasmic-endoplasmic reticulum Ca2+-ATPase was measured in cultured skin fibroblasts from normotensive African-Americans and whites. Cells originated from apparently healthy, normotensive Afr...

journal_title：American journal of hypertension

authors： Yang XY,Aviv A,Hopp L

更新日期：1997-04-01 00:00:00

abstract：BACKGROUND:Blood pressure (BP) measured in the office setting increases from early through later adulthood. However, it is unknown to what extent out-of-office BP derived via ambulatory BP monitoring (ABPM) increases over time, and which participant characteristics and risk factors might contribute to these increases. ...

journal_title：American journal of hypertension

authors： Bundy JD,Jaeger BC,Huffman MD,Knox SS,Thomas SJ,Shimbo D,Booth Iii JN,Lewis CE,Edwards LJ,Schwartz JE,Muntner P

更新日期：2020-11-17 00:00:00

abstract：:The sensitivity and specificity of screening and diagnostic studies for renovascular hypertension has been the focus of debate and disappointment for many years. The use of these studies has been further restricted by the insistence of clinicians that studies provide visual identification of the anatomy of the renal v...

journal_title：American journal of hypertension

authors： Vidt DG

更新日期：1991-12-01 00:00:00

abstract：:Seventeen patients with a diastolic blood pressure over 90 mm Hg were recruited from a running health screening program to participate in a double blind cross-over study of magnesium supplementation (15 mmol Mg2+/day (Emgesan, Kabi Pharmacia) for 3 weeks, followed by 30 mmol Mg2+/day for another 3 weeks, finishing wit...

journal_title：American journal of hypertension

authors： Widman L,Wester PO,Stegmayr BK,Wirell M

更新日期：1993-01-01 00:00:00

abstract：:Stroke-prone spontaneously hypertensive rats (SHRSP), subjected to high NaCl, show severe hypertension, organ damage, and early death. Preventive treatment with angiotensin II type 1 (AT1) receptor antagonists is known to be effective. Previously, we found that angiotensin converting enzyme (ACE) inhibition could redu...

journal_title：American journal of hypertension

authors： Blezer EL,Nicolay K,Koomans HA,Joles JA

更新日期：2001-01-01 00:00:00

abstract：BACKGROUND:Uncontrolled treatment-resistant hypertension (TRH), i.e., blood pressure (BP, mm Hg) ≥140/≥90mm Hg in and out of office on ≥3 different BP medications at optimal doses, is common and has a poor prognosis. Aldosterone antagonist (AA) and renin-guided therapy (RGT) are effective strategies for improving BP co...

journal_title：American journal of hypertension

authors： Egan BM,Laken MA,Sutherland SE,Qanungo S,Fleming DO,Cook AG,Hester WH,Jones KW,Jebaily GC,Valainis GT,Way CF,Wright MB,Davis RA

更新日期：2016-08-01 00:00:00

abstract：BACKGROUND:Beetroot has attracted much attention because of its blood pressure-lowering properties. Although beetroot contains various nutritional compounds, including inorganic nitrate, some of their physiological properties are not fully understood. In this study, we examined whether betanin, a beetroot component, ha...

journal_title：American journal of hypertension

authors： Tawa M,Masuoka T,Yamashita Y,Nakano K,Ishibashi T

更新日期：2020-04-01 00:00:00

abstract：:This article examines the results of the Joint National Committee's Fifth Report on the treatment of hypertension (JNC-V), especially regarding the economic arguments put forth therein. Economics are a poor basis for treatment decisions, as the cheapest therapies may not be the best for any given patient. Broad treatm...

journal_title：American journal of hypertension

authors： Ménard J

更新日期：1994-10-01 00:00:00

abstract：BACKGROUND:The aim was to determine the proportions and correlates of essential hypertension among children in a tertiary pediatric hypertension clinic. METHODS:We evaluated 423 consecutive children and collected demographic and clinical history by retrospective chart review. RESULTS:We identified 275 (65%) hypertens...

journal_title：American journal of hypertension

authors： Gupta-Malhotra M,Banker A,Shete S,Hashmi SS,Tyson JE,Barratt MS,Hecht JT,Milewicz DM,Boerwinkle E

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:This birth cohort study was conducted to investigate the contribution of prenatal and antenatal environmental exposures to later-life hypertensive status. METHODS:Two thousand five hundred and three individuals born in 1921-1954 at the Peking Union Medical College Hospital (PUMCH) were targeted; 2,081 (83.1...

journal_title：American journal of hypertension

authors： Chen X,Zhang ZX,George LK,Wang ZS,Fan ZJ,Xu T,Zhou XL,Han SM,Wen HB,Zeng Y

更新日期：2012-04-01 00:00:00

abstract：:Cocaine causes acute hypertension by blocking catecholamine reuptake. There is evidence that it also impairs the peripheral endothelial nitric oxide system, which is normally vasodilatory. We further explored the role of nitric oxide in cocaine-induced vasoconstriction in anesthetized rats, and in vitro by using isola...

journal_title：American journal of hypertension

authors： Mo W,Singh AK,Arruda JA,Dunea G

更新日期：1998-06-01 00:00:00

abstract：BACKGROUND:Although insulin resistance (IR) is thought to be related to vascular dysfunction, the difference in the relationship of IR to microvasculature and macrovasculature reactivity has not yet been clarified. The present study was conducted to clarify whether the IR is more closely related to the macrovasculature...

journal_title：American journal of hypertension

authors： Yoshida M,Tomiyama H,Yamada J,Matsumoto C,Odaira M,Shiina K,Yamashina A

更新日期：2010-05-01 00:00:00

abstract：:The relation between 24-h ambulatory blood pressure monitoring and echocardiographic left ventricular (LV) anatomy and function was examined in 30 young, normotensive offspring (16 men, 14 women) of hypertensive, parents and in 20 offspring (12 men, 8 women) of normotensive parents, comparable for age, clinical blood ...

journal_title：American journal of hypertension

authors： Galderisi M,Celentano A,Tammaro P,Mureddu GF,Garofalo M,de Simone G,de Divitiis O

更新日期：1993-02-01 00:00:00