Persistent oral candidosis by non-albicans Candida strains including Candida glabrata in a human immunodeficiency virus-infected patient observed over a period of 6 years.

Abstract:

:A 38-year-old woman infected with human immunodeficiency virus (HIV) presented with persistent oral candidosis in which non-albicans Candida strains were the predominant yeasts in most of the examinations performed over a period of 6 years. Oral treatment with fluconazole had no effect on clinical signs of oral candidosis. In 8 of a total of 11 specimens, Candida glabrata, Candida parapsilosis and Candida tropicalis were at least suspected as the causative pathogens of oral candidosis. The non-response to fluconazole in our patient could be explained by in vitro resistance to fluconazole of detected Candida glabrata and Candida tropicalis isolates.

journal_name

Mycoses

journal_title

Mycoses

authors

Hoegl L,Thoma-Greber E,Röcken M,Korting HC

doi

10.1111/j.1439-0507.1998.tb00347.x

subject

Has Abstract

pub_date

1998-09-01 00:00:00

pages

335-8

issue

7-8

eissn

0933-7407

issn

1439-0507

journal_volume

41

pub_type

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