Abstract:
:This randomized, double-blind, placebo-controlled study examined the influence of 6% carbohydrate ingestion on hormonal and lymphocyte proliferative responses (5 total samples over 9 hours) to 2.5 h of high-intensity running by 30 experienced marathon runners. The T-cell response differed between groups, with the placebo group exhibiting a greater increase immediately post-run and greater decrease at 3 h of recovery. No group differences were observed for Con A-, PHA-, or PWM-induced lymphocyte proliferation. However, when PHA was adjusted per T-cell, group differences were observed, highlighted by a decrease in the placebo group immediately post-run. Glucose and cortisol responses differed between groups, with glucose lower and cortisol higher in the placebo group immediately post-run. Post-run glucose correlated negatively with postrun cortisol (r=-0.670, P< 0.001) and epinephrine (r=-0.540, P=0.002). Post-run cortisol also correlated negatively with total lymphocytes and T-cells at 1.5 hours (r=-0.429, P=0.018 and r=-0.424, P=0.019, respectively) and 3 hours (r=-0.566, P=0.001 and r=-0.523, P=0.003, respectively) of recovery. The pre- to post-run change in glucose correlated to the same changes in PHA/T-cell (r=0.456, P=0.011). The data support an interactive effect of carbohydrate ingestion on plasma glucose and cortisol. The data support an interactive effect of carbohydrate ingestion on plasma glucose and cortisol, T-cell trafficking, and cell-adjusted PHA-induced lymphocyte proliferation following long endurance running.
journal_name
Int J Sports Medjournal_title
International journal of sports medicineauthors
Henson DA,Nieman DC,Parker JC,Rainwater MK,Butterworth DE,Warren BJ,Utter A,Davis JM,Fagoaga OR,Nehlsen-Cannarella SLdoi
10.1055/s-2007-971962subject
Has Abstractpub_date
1998-11-01 00:00:00pages
574-80issue
8eissn
0172-4622issn
1439-3964journal_volume
19pub_type
临床试验,杂志文章,随机对照试验abstract::Creatine supplementation has become a common practice among competition athletes participating in different sports over the last few years. The mechanism by which supplementary creatine could have potential ergogenic effects would be an increased muscle creatine and phosphocreatine concentration, leading to a higher r...
journal_title:International journal of sports medicine
pub_type: 杂志文章,meta分析
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journal_title:International journal of sports medicine
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journal_title:International journal of sports medicine
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journal_title:International journal of sports medicine
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journal_title:International journal of sports medicine
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journal_title:International journal of sports medicine
pub_type: 临床试验,杂志文章,随机对照试验
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