The epidemiology of pancreatic diseases in Japan.

abstract：INTRODUCTION:Although cell kinetics of the gastrointestinal mucosa has been extensively examined, that of the pancreas has not been fully analyzed. AIM:To determine the renewal rate of pancreatic cells directly. METHODOLOGY:Postnatal proliferative activity and cellular renewal of the parenchymal cells in ICR mouse pa...

journal_title：Pancreas

authors： Magami Y,Azuma T,Inokuchi H,Moriyasu F,Kawai K,Hattori T

更新日期：2002-03-01 00:00:00

abstract：OBJECTIVES:The aim of this prospective study was to evaluate the diagnostic value of the rapid urinary trypsinogen-2 test strip in post-endoscopic retrograde cholangiopancreatography (ERCP) pancreatitis. METHODS:A total of 150 patients were tested with the urinary trypsinogen-2 test strip and serum levels of amylase a...

journal_title：Pancreas

authors： Tseng CW,Chen CC,Lin SZ,Chang FY,Lin HC,Lee SD

更新日期：2011-11-01 00:00:00

abstract：:This review discusses the current imaging modalities for the diagnosis and staging of solid and cystic pancreatic lesions and for the assessment of acute and chronic pancreatitis, and the future role of emerging technologies in the management of pancreatic diseases. Multidetector row spiral computed tomography is supe...

journal_title：Pancreas

authors： Nichols MT,Russ PD,Chen YK

更新日期：2006-10-01 00:00:00

abstract：:To examine previous work carried out at a single center, i.e., France, on the pathologic features of chronic pancreatitis and to examine geographic differences, 359 cases of chronic pancreatitis from five centers were studied pathologically and the results analyzed according to appropriate statistical methods. It was ...

journal_title：Pancreas

authors： Sahel J,Cros RC,Durbec JP,Sarles H,Bank S,Marks IN,Bettarello A,Duarte I,Guarita D,Machado M

更新日期：1986-01-01 00:00:00

abstract：OBJECTIVES:This study aimed to compare severity of acute pancreatitis (AP) and mortality rates between transferred and nontransferred patients and to determine the factors that influence the decision to transfer. METHODS:A retrospective analysis coding a statewide administrative database in Maryland was conducted. Sev...

journal_title：Pancreas

authors： Anand G,Hutfless SM,Akshintala VS,Khashab MA,Lennon AM,Makary MA,Hirose K,Andersen DK,Kalloo AN,Singh VK

更新日期：2014-10-01 00:00:00

abstract：INTRODUCTION:Hypercytokinemia is known to occur in severe acute pancreatitis, suggesting that the production, deposition, and degradation of the extracellular matrix (ECM) occur actively as a result of the actions of the complicated cytokine network. AIMS AND METHODOLOGY:To examine the influence of cytokines and growt...

journal_title：Pancreas

authors： Nakae H,Endo S,Inoue Y,Fujino Y,Wakabayashi G,Inada K,Sato S

更新日期：2003-03-01 00:00:00

abstract：:Solid pseudopapillary tumor of the pancreas is a rare neoplasm with low malignant potential, which affects predominantly young females. Only approximately 10% to 15% cases of solid pseudopapillary tumors (SPTs) are malignant. We present the case of a 57-year-old woman who developed malignant SPT of the pancreas. Meanw...

journal_title：Pancreas

authors： Ji S,Xu J,Zhang B,Xu Y,Liu C,Long J,Ni Q,Yu X

更新日期：2012-11-01 00:00:00

abstract：OBJECTIVES:Acute pancreatitis is associated with compromised pancreatic microcirculation. Galanin is a vasoactive neuropeptide, but its role in the regulation of pancreatic vascular perfusion (PVP) is unclear. METHODS:Localization of galanin immunoreactivity was investigated by immunohistochemistry, and the effects of...

journal_title：Pancreas

authors： Brooke-Smith ME,Carati CJ,Bhandari M,Toouli J,Saccone GT

更新日期：2008-04-01 00:00:00

abstract：OBJECTIVES:Porcine islets are the most suitable for xeno-islet transplantation. However, it is necessary to establish an effective preservation method against its fragility. Recently, we developed a new cooling and preservation (Keep and Fresh [KFC]; FUJIYA Co, Tokushima, Japan) system, which can maintain viability of ...

journal_title：Pancreas

authors： Ikemoto T,Noguchi H,Fujita Y,Takita M,Shimoda M,Sugimoto K,Jackson A,Naziruddin B,Shimada M,Levy MF,Matsumoto S

更新日期：2010-10-01 00:00:00

abstract：OBJECTIVES:The authors investigated if timing of medical treatment is associated with the analgesic effect of pregabalin or placebo in patients with chronic pancreatitis (CP). METHODS:Sixty-four patients received pregabalin (150-300 mg twice a day) or matching placebo for 3 consecutive weeks. Responders to treatment w...

journal_title：Pancreas

authors： Olesen SS,Graversen C,Bouwense SA,Wilder-Smith OH,van Goor H,Drewes AM

更新日期：2016-03-01 00:00:00

abstract：:A 50-year-old female was referred to our hospital because of postprandial epigastric pain and pancreatic head mass. On admission, an elastic hard mass with tenderness was palpable in the epigastric region. Laboratory findings showed no abnormalities, except for a slightly elevated C-reactive protein value and iron def...

journal_title：Pancreas

authors： Taguchi M,Nishikawa S,Matsuoka H,Narita R,Abe S,Fukuda K,Miyamoto H,Taniguchi H,Otsuki M

更新日期：2006-11-01 00:00:00

abstract：OBJECTIVE:Image-guided radiation therapy allows precise tumor targeting using real-time tracking of radiopaque fiducial markers. To enable appropriate tracking, it is recommended to place fiducials with "ideal fiducial geometry" (IFG). Our objectives were to determine the proportion of patients in whom IFG can be achie...

journal_title：Pancreas

authors： Majumder S,Berzin TM,Mahadevan A,Pawa R,Ellsmere J,Sepe PS,Larosa SA,Pleskow DK,Chuttani R,Sawhney MS

更新日期：2013-05-01 00:00:00

abstract：OBJECTIVES:Pancreatic carcinoma etiology and molecular pathogenesis is weakly understood. According to the assumption that genetic variation in carcinogen metabolism further modifies the risk of exposure-related cancers, an association of functional polymorphisms in oxidative stress-modifying genes superoxide dismutase...

journal_title：Pancreas

authors： Mohelnikova-Duchonova B,Marsakova L,Vrana D,Holcatova I,Ryska M,Smerhovsky Z,Slamova A,Schejbalova M,Soucek P

更新日期：2011-01-01 00:00:00

abstract：OBJECTIVE:Epithelial-mesenchymal transition may interfere with the differentiation of cultured pancreatic acinar cells toward endocrine cells. Therefore, it will be important to investigate into detail the reprogramming of human pancreatic acinar cells toward a mesenchymal phenotype: the association with acinoductal tr...

journal_title：Pancreas

authors： De Waele E,Wauters E,Ling Z,Bouwens L

更新日期：2014-10-01 00:00:00

abstract：:The effect on endogenous beta-endorphins of a new synthetic protease inhibitor was studied in acute pancreatitis. Pancreatitis was induced by the injection of autologous bile mixed with trypsin into the main pancreatic duct after ligation of the accessory duct. Plasma beta-endorphin concentrations and cardiovascular f...

journal_title：Pancreas

authors： Satake K,Hiura A,Ha SS,Nishiwaki H,Umeyama K

更新日期：1991-07-01 00:00:00

abstract：:To assess the role of stapling devices and routine gastroenterostomy in palliative bypass surgery, the hospital records of 150 consecutive patients with unresectable, histologically proven pancreatic adenocarcinoma requiring palliative bypass procedure were reviewed. During recent years staplers have gained increasing...

journal_title：Pancreas

authors： Kairaluoma MI,Kiviniemi H,Laitinen S,Ståhlberg M

更新日期：1987-01-01 00:00:00

abstract：:The aim of the study was to establish whether correlations were discernible between calcification, smoking, and other variables--including alcohol intake--in chronic pancreatitis. A total of 637 patients with chronic pancreatitis diagnosed over the period of 1973-1989 were reviewed. Only patients who had had one or mo...

journal_title：Pancreas

authors： Cavallini G,Talamini G,Vaona B,Bovo P,Filippini M,Rigo L,Angelini G,Vantini I,Riela A,Frulloni L

更新日期：1994-01-01 00:00:00

abstract：OBJECTIVES:Ecological studies support the hypothesis that there is an association between vitamin D and pancreatic cancer (PaCa) mortality, but observational studies are somewhat conflicting. We sought to contribute further data to this issue by analyzing the differences in PaCa mortality across the eastern states of A...

journal_title：Pancreas

authors： Neale RE,Youlden DR,Krnjacki L,Kimlin MG,van der Pols JC

更新日期：2009-05-01 00:00:00

abstract：OBJECTIVES:The aim of this study was to identify differentially expressed proteins in the pancreatic tissue of hepatic alcohol dehydrogenase-deficient deer mice fed ethanol to understand metabolic basis and mechanism of alcoholic chronic pancreatitis. METHODS:Mice were fed liquid diet containing 3.5 g% ethanol daily f...

journal_title：Pancreas

authors： Bhopale KK,Amer SM,Kaphalia L,Soman KV,Wiktorowicz JE,Shakeel Ansari GA,Kaphalia BS

更新日期：2017-07-01 00:00:00

abstract：OBJECTIVES:Literature addressing the significance of lymph node positivity in the management of nonfunctional pancreatic neuroendocrine tumors (PNETs) is conflicting. METHODS:The National Cancer Data Base was queried for patients who underwent surgical resection of nonfunctional PNETs between 1998 and 2011. Clinical d...

journal_title：Pancreas

authors： Jutric Z,Grendar J,Hoen HM,Cho SW,Cassera MA,Newell PH,Hammill CW,Hansen PD,Wolf RF

更新日期：2017-08-01 00:00:00

abstract：OBJECTIVES:A simple urinary trypsinogen-2 test was evaluated for the diagnosis of acute pancreatitis. METHODS:This prospective multicenter study enrolled consecutive patients with acute abdominal pain who presented to the emergency department or who were hospitalized at 1 of 21 medical institutions in Japan. Patients ...

journal_title：Pancreas

authors： Mayumi T,Inui K,Maetani I,Yokoe M,Sakamoto T,Yoshida M,Ko S,Hirata K,Takada T,Urinary Trypsinogen-2 Dipstick for Acute Pancreatitis Study Group of Japanese Society of Abdominal Emergency Medicine (UtrAP Study Group).

更新日期：2012-08-01 00:00:00

abstract：:beta-1,4-Galactosyltransferase (GalTase) is the glycosyltransferase in the Golgi apparatus that transfers galactose from UDP-galactose to terminal N-acetylglucosamine residues in glycoconjugates with formation of a beta-1,4 linkage. Neoplasms undergo various changes in the carbohydrate moieties of their glycoconjugate...

journal_title：Pancreas

authors： Yamamoto K,Kawakami H,Sugiyama M,Atomi Y,Hirano H

更新日期：1999-08-01 00:00:00

abstract：OBJECTIVE:This study developed a novel protocol for creating an acute necrotizing pancreatitis model in rats using L-arginine. METHODS:Anesthetic laparotomy was performed on the upper abdomen, and the pancreatic parenchyma of Sprague-Dawley rats was injected with 1 mL of sterilized L-arginine solution at 5 different l...

journal_title：Pancreas

authors： Guo F,Zheng S,Gao X,Zhang Q,Liu J

更新日期：2015-03-01 00:00:00

abstract：OBJECTIVES:Human telomerase reverse transcriptase (hTERT), one of the subunits of telomerase, is a promising diagnostic marker for pancreatic cancer. In the present study, we did a large-scale analysis of 115 preoperative pancreatic juice specimens to evaluate the feasibility of detection of hTERT expression by immunoh...

journal_title：Pancreas

authors： Nakashima A,Murakami Y,Uemura K,Hayashidani Y,Sudo T,Hashimoto Y,Ohge H,Oda M,Sueda T,Hiyama E

更新日期：2009-07-01 00:00:00

abstract：OBJECTIVES:The objective of this study was to evaluate racial differences in cancer treatment and survival in gastroenteropancreatic neuroendocrine tumor (GEP-NET) patients. METHODS:Using the Surveillance, Epidemiology, and End Results Registry, we identified patients with GEP-NETs of the stomach, small intestine (SI)...

journal_title：Pancreas

authors： Kessel E,Naparst M,Alpert N,Diaz K,Ahn E,Wolin E,Taioli E,Kim MK

更新日期：2021-01-01 00:00:00

abstract：:In this study, we performed a detailed analysis of the immunoreactive (IR) patterns and tissue distribution of vasoactive intestinal polypeptide (VIP), neuropeptide Y (NPY), and gastrin-releasing peptide (GRP) in the feline pancreas by means of immunohistochemical and radioimmunological techniques. Immunoreactivity fo...

journal_title：Pancreas

authors： De Giorgio R,Sternini C,Brecha NC,Widdison AL,Karanjia ND,Reber HA,Go VL

更新日期：1992-01-01 00:00:00

abstract：OBJECTIVES:To study the association of binge drinking and the outcomes of severe acute pancreatitis (SAP). METHODS:This retrospective study included 347 patients with first-attack SAP from January 2001 to February 2004. On the basis of the history of binge drinking or not, the patients were divided into the alcohol (n...

journal_title：Pancreas

authors： Deng L,Xue P,Huang L,Yang X,Wan M,Xia Q

更新日期：2010-03-01 00:00:00

abstract：OBJECTIVE:This study aimed to investigate whether the previously described differentiating islet-like aggregates of human pancreatic adenocarcinoma cells (PANC-1) develop glucose response and exhibit intercellular communication. METHODS:Fura 2-loaded PANC-1 cells in serum-free medium were assayed for changes in cytoso...

journal_title：Pancreas

authors： Hiram-Bab S,Shapira Y,Gershengorn MC,Oron Y

更新日期：2012-03-01 00:00:00

abstract：:Changes in pancreatic growth and in mRNA concentrations in rat pancreas were monitored by dot-blot hybridization with cloned cDNAs of rat amylase, chymotrypsinogen B, proinsulin I, and actin during the pre- and postnatal period in the rat. Wistar rats were killed at the 18th day of gestation and at the 1st, 10th, 20th...

journal_title：Pancreas

authors： Iovanna JL,Dusetti N,Cadenas B,Calvo EL

更新日期：1990-07-01 00:00:00

abstract：OBJECTIVES:Pancreatic cancer (PC), a common cause of cancer death, is rarely diagnosed at an early stage. Early detection of PC may improve outcomes in affected patients. This study evaluated the utility of screening of high-risk individuals (HRIs) using an endoscopic ultrasound (EUS)-only approach to detect early mali...

journal_title：Pancreas

authors： Gangi A,Malafa M,Klapman J

更新日期：2018-05-01 00:00:00