Endothelial nitric oxide synthase (eNOS) is localized to Müller cells in all vertebrate retinas.

Abstract:

:The distribution of endothelial nitric oxide synthase immunoreactivity (eNOS-IR) was investigated in the retinas of all phylogenetic vertebrate classes by using a monoclonal eNOS antibody. Confocal light microscopy showed immunoreactive labeling in Müller cells of fish, frog, salamander, turtle, chicken, rat, ground squirrel, and monkey retina. In vascularized retinas (rat, monkey), astrocytes and some blood vessels were also stained. Furthermore, eNOS-IR was localized to axon terminals of turtle and fish horizontal cells. These observations are the first to show the presence of eNOS-IR in Muller glia and horizontal cell structures of the vertebrate retina.

journal_name

Vision Res

journal_title

Vision research

authors

Haverkamp S,Kolb H,Cuenca N

doi

10.1016/s0042-6989(99)00007-3

subject

Has Abstract

pub_date

1999-07-01 00:00:00

pages

2299-303

issue

14

eissn

0042-6989

issn

1878-5646

pii

S0042-6989(99)00007-3

journal_volume

39

pub_type

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