Developmental lead exposure selectively alters the scotopic ERG component of dark and light adaptation and increases rod calcium content.

Abstract:

:Electrophysiological studies have established that lead exposure produces selective rod deficits. The present electroretinographic (ERG) and correlated calcium experiments examined whether low-level or moderate-level developmental lead exposure (peak blood lead of 19 and 59 micrograms/dl, respectively) altered dark adaptation and/or light adaptation. Developmental lead exposure produced long-term dose-response (1) decreases in the slope of the increment threshold function only at scotopic adapting backgrounds, (2) decreases only in the sensitivity of the rod phase of dark adaptation and (3) increases in the calcium content of rod outer segments which may partially mediate the ERG results. The relevance and applicability of these data to lead-exposed children have yet to be established.

journal_name

Vision Res

journal_title

Vision research

authors

Fox DA,Katz LM

doi

10.1016/0042-6989(92)90134-5

subject

Has Abstract

pub_date

1992-02-01 00:00:00

pages

249-55

issue

2

eissn

0042-6989

issn

1878-5646

pii

0042-6989(92)90134-5

journal_volume

32

pub_type

杂志文章
  • Integration of stereopsis and motion shape cues.

    abstract::A global shape judgement task was used to investigate the combination of stereopsis and kinetic depth. With both cues present, there were no distortions of shape perception, even under conditions where either cue alone did show such distortions. We suggest that the addition of motion information overcomes the stereo d...

    journal_title:Vision research

    pub_type: 杂志文章

    doi:10.1016/0042-6989(94)90106-6

    authors: Johnston EB,Cumming BG,Landy MS

    更新日期:1994-09-01 00:00:00

  • What a difference a parameter makes: a psychophysical comparison of random dot motion algorithms.

    abstract::Random dot motion (RDM) displays have emerged as one of the standard stimulus types employed in psychophysical and physiological studies of motion processing. RDMs are convenient because it is straightforward to manipulate the relative motion energy for a given motion direction in addition to stimulus parameters such ...

    journal_title:Vision research

    pub_type: 杂志文章

    doi:10.1016/j.visres.2009.03.019

    authors: Pilly PK,Seitz AR

    更新日期:2009-06-01 00:00:00

  • Working memory can guide pop-out search.

    abstract::Top-down feedback from working memory (WM) can exert an early and involuntary influence on visual selection for targets that are relatively difficult to discriminate [Soto, D., Heinke, D., Humphreys, G. W., & Blanco, M. J. (2005) Journal of Experimental Psychology: Human Perception and Performance, 31, 248]. Here, we ...

    journal_title:Vision research

    pub_type: 杂志文章

    doi:10.1016/j.visres.2005.09.008

    authors: Soto D,Humphreys GW,Heinke D

    更新日期:2006-03-01 00:00:00

  • An adaptation-induced pop-out in visual search.

    abstract::The present study demonstrates that an object embedded in an array of identical objects can pop-out. Dependent on the stimuli preceding the search display, local (chromatic) adaptation causes an identical object to pop-out because it appears to have a colour (Expt 1) or brightness (Expt 2) that is slightly different f...

    journal_title:Vision research

    pub_type: 杂志文章

    doi:10.1016/0042-6989(93)90113-b

    authors: Theeuwes J,Lucassen MP

    更新日期:1993-11-01 00:00:00

  • Specific effects of spatial-frequency uncertainty and different cue types on contrast detection: data and models.

    abstract::If the spatial-frequency of sinusoidal signals in a contrast-detection experiment varies randomly from trial to trial, then performance is decreased compared with that in a situation where it remains constant. This spatial-frequency uncertainty effect can more or less be compensated by presenting informative cues shor...

    journal_title:Vision research

    pub_type: 杂志文章

    doi:10.1016/0042-6989(96)00088-0

    authors: Hübner R

    更新日期:1996-11-01 00:00:00

  • Ultra-rapid categorisation of natural scenes does not rely on colour cues: a study in monkeys and humans.

    abstract::In a rapid categorisation task, monkeys and humans had to detect a target (animal or food) in briefly flashed (32 ms) and previously unseen natural images. Removing colour cues had very little effect on average performance. Impairments were restricted to a mild accuracy drop (in some human subjects) and a small reacti...

    journal_title:Vision research

    pub_type: 杂志文章

    doi:10.1016/s0042-6989(00)00083-3

    authors: Delorme A,Richard G,Fabre-Thorpe M

    更新日期:2000-01-01 00:00:00

  • A multiscale spatial filtering account of the White effect, simultaneous brightness contrast and grating induction.

    abstract::Blakeslee and McCourt ((1997) Vision Research, 37, 2849-2869) demonstrated that a multiscale array of two-dimensional difference-of-Gaussian (DOG) filters provided a simple but powerful model for explaining a number of seemingly complex features of grating induction (GI), while simultaneously encompassing salient feat...

    journal_title:Vision research

    pub_type: 杂志文章

    doi:10.1016/s0042-6989(99)00119-4

    authors: Blakeslee B,McCourt ME

    更新日期:1999-10-01 00:00:00

  • Pooling elementary motion signals into perception of global motion direction.

    abstract::Six observers were asked to indicate in which of two opposite directions, to the right or to the left, an entire display appeared to move, based on the proportion of right vs leftward motion elements, each of which was distinctly visible. The performance of each observer was described by Thurstone's discriminative pro...

    journal_title:Vision research

    pub_type: 杂志文章

    doi:10.1016/j.visres.2011.07.004

    authors: Raidvee A,Averin K,Kreegipuu K,Allik J

    更新日期:2011-09-01 00:00:00

  • The role of the superior colliculus in saccade initiation: a study of express saccades and the gap effect.

    abstract::Neural mechanisms underlying the initiation of saccadic eye movements were studied by recording the activity of neurons in the superior colliculus of rhesus monkeys that had extensive experience on the gap task using targets restricted to one visual field. The superposition of visual activation upon the increased exci...

    journal_title:Vision research

    pub_type: 杂志文章

    doi:10.1016/s0042-6989(00)00133-4

    authors: Sparks D,Rohrer WH,Zhang Y

    更新日期:2000-01-01 00:00:00

  • Rod light and dark adaptation influence cone-mediated spatial acuity.

    abstract::The influence of rod light and dark adaptation upon cone mediated spatial acuity was studied in the near parafoveal retina of normal human observers. The luminance just necessary to detect squarewave test gratings of variable frequency provided an index of spatial acuity. Such thresholds were determined in the presenc...

    journal_title:Vision research

    pub_type: 杂志文章

    doi:

    authors: Naarendorp F,Denny N,Frumkes TE

    更新日期:1988-01-01 00:00:00

  • Simultaneous recognition of two spatial-frequency components.

    abstract::A two-frequency two-response paradigm was employed. The stimulus on any trial was a compound grating containing two sinusoidal components of different spatial frequencies where the contrast in one or both components could be zero. The observer gave two responses each indicating confidence that one of the two component...

    journal_title:Vision research

    pub_type: 杂志文章

    doi:10.1016/0042-6989(82)90152-3

    authors: Hirsch J,Hylton R,Graham N

    更新日期:1982-01-01 00:00:00

  • Perceived surface shape not features determines correspondence strength in apparent motion.

    abstract::Previous psychophysical studies have revealed that shape similarity can affect apparent motion correspondence. Such results however, do not specify the level of representation, at which shape similarity is defined. We sought to understand this question by using a 2 x 2 competitive apparent motion paradigm. We manipula...

    journal_title:Vision research

    pub_type: 杂志文章

    doi:10.1016/0042-6989(94)90322-0

    authors: He ZJ,Nakayama K

    更新日期:1994-08-01 00:00:00

  • An unsupervised learning model of neural plasticity: Orientation selectivity in goggle-reared kittens.

    abstract::The selectivities of neurons in primary visual cortex are often considered to be adapted to the statistics of natural images. Accordingly, simple cell-like tuning emerges when unsupervised learning models that seek sparse representations of input probabilities are trained on natural scenes. However, orientation tuning...

    journal_title:Vision research

    pub_type: 杂志文章

    doi:10.1016/j.visres.2007.07.023

    authors: Hsu AS,Dayan P

    更新日期:2007-10-01 00:00:00

  • "Lens mitochondria" in the retinal cones of the tree-shrew Tupaia belangeri.

    abstract::In all mammals, the mitochondria of the cones of the retina are concentrated in the inner segment. Uniquely in tree-shrews (Tupaia, Scandentia, Mammalia), a "megamitochondrion" exhibiting highly specialized systems of densely packed cristae and a very electron dense matrix, is located apically in the inner segment. Th...

    journal_title:Vision research

    pub_type: 杂志文章

    doi:10.1016/s0042-6989(96)00199-x

    authors: Knabe W,Skatchkov S,Kuhn HJ

    更新日期:1997-02-01 00:00:00

  • Recognition of band-pass filtered hand-written numerals in foveal and peripheral vision.

    abstract::The purpose of the present study was to find out what differences between foveal and peripheral pattern recognition remain unexplained by the inhomogeneities of retinal sampling and the optics of the eye. We measured contrast thresholds for pattern recognition at different eccentricities. The effects of retinal sampli...

    journal_title:Vision research

    pub_type: 杂志文章

    doi:10.1016/s0042-6989(98)00062-5

    authors: Näsänen R,O'Leary C

    更新日期:1998-12-01 00:00:00

  • Effects of pictorially-defined surfaces on visual search.

    abstract::Three experiments of visual search for a cube (for a square pillar in Experiment 3) with an odd conjunction of orientation of faces and color (a cube with a red top face and a green right face among cubes with a green top face and a red right face, for example) showed that the search is made more efficient by arrangin...

    journal_title:Vision research

    pub_type: 杂志文章

    doi:10.1016/s0042-6989(03)00300-6

    authors: Morita H,Kumada T

    更新日期:2003-08-01 00:00:00

  • Nonlocal interactions in color perception: nonlinear processing of chromatic signals from remote inducers.

    abstract::The perceived color of an object depends on the chromaticity of its immediate background. But color appearance is also influenced by remote chromaticities. To quantify these influences, the effects of remote color fields on the appearance of a fixated 2 degrees test field were measured using a forced-choice method. Ch...

    journal_title:Vision research

    pub_type: 杂志文章

    doi:10.1016/s0042-6989(01)00017-7

    authors: Wachtler T,Albright TD,Sejnowski TJ

    更新日期:2001-05-01 00:00:00

  • Focal cone ERGs of rhodopsin Pro347Leu transgenic rabbits.

    abstract::A rhodopsin P347L transgenic (Tg) rabbit, a model of retinitis pigmentosa, has been generated in our laboratory. The purpose of this study was to determine the properties of focal areas of the retina in this rabbit model during the course of retinal degeneration. To accomplish this, we recorded focal ERGs from wild-ty...

    journal_title:Vision research

    pub_type: 杂志文章

    doi:10.1016/j.visres.2013.08.006

    authors: Ueno S,Koyasu T,Kominami T,Sakai T,Kondo M,Yasuda S,Terasaki H

    更新日期:2013-10-18 00:00:00

  • Stiles-Crawford effect of the first kind: assessment of photoreceptor alignments following dark patching.

    abstract::Properties of presumed mechanisms controlling photoreceptor alignments are partially defined. A phototropic mechanism normally dominates alignment, but do modest changes in orientations occur with dark patching? Here, new photopic Stiles-Crawford (SCE-I) determinations were made before patching (pre-patch), just after...

    journal_title:Vision research

    pub_type: 杂志文章

    doi:10.1016/s0042-6989(00)00228-5

    authors: Kono M,Enoch JM,Strada E,Shih P,Srinivasan R,Lakshminarayanan V,Susilasate W,Graham A

    更新日期:2001-01-01 00:00:00

  • Asymmetry of perceived motion smear during head and eye movements: evidence for a dichotomous neural categorization of retinal image motion.

    abstract::We measured perceived motion smear when retinal image motion was created either by a physically moving object or by movement of the eyes or head. Consistent with previous reports, the extent of perceived motion smear during an eye or head movement is less than that produced by physical object motion when the eyes are ...

    journal_title:Vision research

    pub_type: 杂志文章

    doi:10.1016/j.visres.2004.12.004

    authors: Tong J,Patel SS,Bedell HE

    更新日期:2005-06-01 00:00:00

  • Parahippocampal cortex is involved in material processing via echoes in blind echolocation experts.

    abstract::Some blind humans use sound to navigate by emitting mouth-clicks and listening to the echoes that reflect from silent objects and surfaces in their surroundings. These echoes contain information about the size, shape, location, and material properties of objects. Here we present results from an fMRI experiment that in...

    journal_title:Vision research

    pub_type: 杂志文章

    doi:10.1016/j.visres.2014.07.004

    authors: Milne JL,Arnott SR,Kish D,Goodale MA,Thaler L

    更新日期:2015-04-01 00:00:00

  • The recognition of everyday objects changes grasp scaling.

    abstract::Current concepts of action and perception emphasise a dissociation between conscious visual recognition and visual action control. These models do not expect an effect of the recognisable identity of an object on the kinematic parameterisation of grasping movements under binocular viewing conditions without pre-test l...

    journal_title:Vision research

    pub_type: 杂志文章

    doi:10.1016/j.visres.2012.06.019

    authors: Borchers S,Himmelbach M

    更新日期:2012-08-15 00:00:00

  • Influence of reading skill and word length on fixation-related brain activity in school-aged children during natural reading.

    abstract::Word length is one of the main determinants of eye movements during reading and has been shown to influence slow readers more strongly than typical readers. The influence of word length on reading in individuals with different reading skill levels has been shown in separate eye-tracking and electroencephalography stud...

    journal_title:Vision research

    pub_type: 杂志文章

    doi:10.1016/j.visres.2019.07.008

    authors: Loberg O,Hautala J,Hämäläinen JA,Leppänen PHT

    更新日期:2019-12-01 00:00:00

  • Visual attention modifies spectral sensitivity of nystagmic eye movements.

    abstract::If we look out of the window of a travelling train our eyes move rapidly back and forth (saccadic movement). With no attention to individual objects, gaze velocity is low but nystagmic frequency is high (stare nystagmus). If we are interested in individual objects, the angular velocity of gaze is high and the nystagmi...

    journal_title:Vision research

    pub_type: 杂志文章

    doi:10.1016/s0042-6989(98)00212-0

    authors: von Campenhausen M,Kirschfeld K

    更新日期:1999-04-01 00:00:00

  • Colored neon flanks and line gap enhancement.

    abstract::When a colored line connects two black (or differently colored) lines across a gap, colored neon flanks are seen on either side of it. These flanks extend over gap sizes of 50 min arc foveally and are not explained by Bezold-type assimilation. They may be elicited by black lines as short as 6 min arc adjoining the col...

    journal_title:Vision research

    pub_type: 杂志文章

    doi:10.1016/0042-6989(84)90185-8

    authors: Redies C,Spillmann L,Kunz K

    更新日期:1984-01-01 00:00:00

  • Motion interference: perturbing perceived direction.

    abstract::The minimum stimulus necessary to define motion is a change in position from one location to another in time, but past studies have provided evidence that the human motion system integrates motion over more than two positions. In this study we demonstrate strong sequential interactions affecting perceived direction in...

    journal_title:Vision research

    pub_type: 杂志文章

    doi:10.1016/s0042-6989(97)00084-9

    authors: Welch L,Macleod DI,Mckee SP

    更新日期:1997-10-01 00:00:00

  • Differential DNA binding activities of the transcription factors AP-1 and Oct-1 during light-induced apoptosis of photoreceptors.

    abstract::The activity of transcription factors like AP-1 and Oct-1 is critical for the regulation of gene expression. Whereas Oct-1 mainly regulates the expression of housekeeping genes, AP-1 is often involved in cellular responses to external stimuli and plays an essential role in the regulation of light-induced apoptosis of ...

    journal_title:Vision research

    pub_type: 杂志文章

    doi:10.1016/s0042-6989(98)00313-7

    authors: Hafezi F,Marti A,Grimm C,Wenzel A,Remé CE

    更新日期:1999-07-01 00:00:00

  • Contrast discrimination with and without spatial uncertainty.

    abstract::The main purpose of these experiments was to examine in detail how successfully the uncertainty reduction explanation accounts for the effects of spatial cues in a temporal forced-choice contrast discrimination task in which any one of four well-separated Gabor patches is incremented. In preliminary experiments, it wa...

    journal_title:Vision research

    pub_type: 杂志文章

    doi:10.1016/s0042-6989(01)00254-1

    authors: Nachmias J

    更新日期:2002-01-01 00:00:00

  • Habituation-like effects cause a significant decrease in response in MRI neuroactivation during visual stimulation.

    abstract::A wide range of rest/stimulus cycle durations (40-360 sec) is reported to have been used by various groups for MRI neuroactivation studies of the visual cortex. In this paper we demonstrate a clear habituation-like response for longer cycle durations which results in a halving of apparent activation between cycle dura...

    journal_title:Vision research

    pub_type: 杂志文章

    doi:10.1016/s0042-6989(97)85231-5

    authors: Condon B,McFadzean R,Hadley DM,Bradnam MS,Shahani U

    更新日期:1997-05-01 00:00:00

  • Taurine depletion leads to loss of rat optic nerve axons.

    abstract::The number of axons in the optic nerve have been examined in rat pups raised by control or taurine-depleted mothers, at 21, 28 and 40 days after birth. Optic nerves from the mother rats were also studied. Taurine depletion of dams and some litters after weaning was achieved by in vivo treatment with guanidinoethyl sul...

    journal_title:Vision research

    pub_type: 杂志文章

    doi:10.1016/0042-6989(88)90133-2

    authors: Lake N,Malik N,De Marte L

    更新日期:1988-01-01 00:00:00