Activity of omnipause neurons during "staircase saccades" elicited by persistent microstimulation of the superior colliculus.

Abstract:

:We have recorded the activity of omnipause neurons (OPNs) in the raphe interpositus during so-called staircase saccades produced by prolonged activation of the superior colliculus (SC) by microstimulation. By showing that OPNs cyclically pause during the periodic movements produced by the steady activation function, we reveal the functional relationship of the OPNs within the recurrent brainstem network that produces dynamic, closed-loop, and feedback control of saccades. Despite persistent, steady activation of the SC, the OPNs followed the periodic activity of the brainstem burst generator. This reveals a dominant influence of the oscillating brainstem circuit over descending control from the SC.

journal_name

Vision Res

journal_title

Vision research

authors

Paul K,Gnadt JW

doi

10.1016/j.visres.2006.05.014

subject

Has Abstract

pub_date

2006-10-01 00:00:00

pages

3430-42

issue

20

eissn

0042-6989

issn

1878-5646

pii

S0042-6989(06)00245-8

journal_volume

46

pub_type

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