Malignancy in Peutz-Jeghers syndrome? The pitfall of pseudo-invasion.

Abstract:

:Peutz-Jeghers syndrome is a malignancy-associated polyposis syndrome. We describe a histopathologic phenomenon easily encountered when examining the nature of Peutz-Jeghers polyps but that is underreported in the literature. This phenomenon of "pseudo-invasion" may mimic invasive carcinoma due to epithelial displacement and erroneously give the impression, both macroscopically and microscopically, that a malignancy is involved. This potential pitfall is illustrated by the case of a patient with Peutz-Jeghers syndrome who was thought to harbor a metastasizing adenocarcinoma in his small bowel with peritoneal metastasis as a perioperative finding. Histologic examination, however, revealed pseudo-invasion.

journal_name

J Clin Gastroenterol

authors

Westerman AM,van Velthuysen ML,Bac DJ,Schouten WR,Wilson JH

doi

10.1097/00004836-199707000-00023

subject

Has Abstract

pub_date

1997-07-01 00:00:00

pages

387-90

issue

1

eissn

0192-0790

issn

1539-2031

journal_volume

25

pub_type

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