Pathophysiology of Nonalcoholic Steatohepatitis.

abstract：:Zoonotic visceral leishmaniasis is common in western Mediterranean countries. A strong link between visceral leishmaniasis and human immunodeficiency virus (coinfection) has been proved, especially in Spain, which is an endemic area. This suggests that Leishmania may behave opportunistically. We report a case of colon...

journal_title：Journal of clinical gastroenterology

authors： Sebastián JJ,García S,Soria MT,Pac J,Vicente J,Uribarrena R

更新日期：1997-12-01 00:00:00

abstract：:Cardiac and circulatory failure are the main causes of hypoxic hepatitis. In a prospective study of 142 cases of hypoxic hepatitis collected during a 10-year period, we encountered two cases resulting from extreme arterial hypoxemia without congestive heart failure, cor pulmonale, or circulatory failure. Both patients...

journal_title：Journal of clinical gastroenterology

authors： Henrion J,Colin L,Schapira M,Heller FR

更新日期：1997-06-01 00:00:00

abstract：:The clinical recognition of Helicobacter pylori gastritis in children with recurrent abdominal pain is difficult. We assessed the value of a simplified 13C urea breath test (13C-UBT) in a selected group of children with nocturnal waking and disruptive recurrent abdominal pain who fulfilled criteria for endoscopy. Gast...

journal_title：Journal of clinical gastroenterology

authors： Eltumi M,Brueton MJ,Francis N

更新日期：1999-04-01 00:00:00

abstract：GOALS:To evaluate the diagnostic yield of push enteroscopy in relation to indication and compare the yield in patients who had capsule endoscopy followed by push enteroscopy against capsule endoscopy naive patients. BACKGROUND:With the advent of capsule endoscopy the role of push enteroscopy needs to be reevaluated. ...

journal_title：Journal of clinical gastroenterology

authors： Sidhu R,McAlindon ME,Kapur K,Hurlstone DP,Wheeldon MC,Sanders DS

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:Split-dose regimens (SpDs) were recommended as a first choice for bowel preparation, whereas same-day regimens (SaDs) were recommended as an alternative; however, randomized trials compared them with mixed results. The meta-analysis was aimed at clarifying efficacy level between the 2 regimens. MATERIALS AN...

journal_title：Journal of clinical gastroenterology

authors： Cheng YL,Huang KW,Liao WC,Luo JC,Lan KH,Su CW,Wang YJ,Hou MC

更新日期：2018-05-01 00:00:00

abstract：GOALS:The aim of this study was to compare celecoxib with loxoprofen for protection of small intestine. BACKGROUND:RCT studies report that COX-2 selective inhibitor celecoxib induces fewer small intestinal injuries than nonselective nonsteroidal anti-inflammatory drugs (NSAIDs). Loxoprofen is a prodrug nonselective NS...

journal_title：Journal of clinical gastroenterology

authors： Fujimori S,Hanada R,Hayashida M,Sakurai T,Ikushima I,Sakamoto C

更新日期：2016-03-01 00:00:00

abstract：GOALS:To describe the epidemiology and microbiologic characteristics of bloodstream infections (BSIs) in patients receiving long-term total parenteral nutrition (TPN). BACKGROUND:Home TPN therapy has been reported as a risk factor for BSI. However, little knowledge exists regarding the epidemiology of BSIs in this pat...

journal_title：Journal of clinical gastroenterology

authors： Marra AR,Opilla M,Edmond MB,Kirby DF

更新日期：2007-01-01 00:00:00

abstract：GOALS:To describe current hepatitis C virus (HCV) treatment practices in the United States and identify physician characteristics associated with the use of first generation direct-acting antivirals (DAAs). BACKGROUND:HCV treatment practice patterns have not been assessed after the introduction of DAA, which are now c...

journal_title：Journal of clinical gastroenterology

authors： Chen EY,Lee WM,Hynan LS,Singal AG

更新日期：2013-10-01 00:00:00

abstract：:Meal period exclusion from 24-h pH testing allows better separation between controls and patients with gastroesophageal reflux disease. We reviewed the results of 24-h pH studies of 350 patients with reflux symptoms. They were divided into two groups based on the 95th percentile of the total percentage of time when pH...

journal_title：Journal of clinical gastroenterology

authors： Ter RB,Johnston BT,Castell DO

更新日期：1997-07-01 00:00:00

abstract：:During the past three decades, important advances in our understanding of the pathophysiology of chronic pancreatitis (CP), improved results of major pancreatic resections (including pancreatoduodenectomy), and integration of sophisticated diagnostic methods in clinical practice resulted in significant changes in our ...

journal_title：Journal of clinical gastroenterology

authors： Sakorafas GH,Tsiotou AG

更新日期：2002-01-01 00:00:00

abstract：GOAL:The goal of this study was to evaluate the safety of propofol when used by gastroenterologists in patients who have an inadequate response to standard sedation (narcotics and benzodiazepines). BACKGROUND:Many patients fail to achieve adequate sedation from narcotics and benzodiazepines during colonoscopy. The adm...

journal_title：Journal of clinical gastroenterology

authors： Okeke FC,Shaw S,Hunt KK,Korsten MA,Rosman AS

更新日期：2016-09-01 00:00:00

abstract：GOAL:The goal of this study was to investigate the relationship between Helicobacter pylori (H. pylori) infection and short-segment and long-segment Barrett's esophagus (SSBE and LSBE). BACKGROUND:H. pylori infection is reported to be inversely associated with Barrett's esophagus (BE) in western countries. However, th...

journal_title：Journal of clinical gastroenterology

authors： Usui G,Sato H,Shinozaki T,Jinno T,Fujibayashi K,Ishii K,Horiuchi H,Morikawa T,Gunji T,Matsuhashi N

更新日期：2020-05-01 00:00:00

abstract：:The present study was designed to assess histologic and ultrastructural features of gastric mucosa in the areas of grossly healed ulcers (acetic acid-induced gastric ulcers) in rats. The specific question we studied was whether the structure and cellular composition of the gastric mucosa in an area of grossly healed u...

journal_title：Journal of clinical gastroenterology

authors： Tarnawski A,Hollander D,Krause WJ,Dabros W,Stachura J,Gergely H

更新日期：1990-01-01 00:00:00

abstract：:Diverticular disease of the colon is quite common in developed countries, and its prevalence increases with age. Although present in perhaps two thirds of the elderly population, the large majority of patients will remain entirely asymptomatic. Nonetheless, an estimated 20% of those affected may manifest clinical illn...

journal_title：Journal of clinical gastroenterology

authors： Stollman NH,Raskin JB

更新日期：1999-10-01 00:00:00

abstract：:Crohn's disease is believed to have an immunologic basis. The importance of the CD4 cell in particular has been supported by several reports of patients whose symptoms of Crohn's disease resolved after a decline in CD4 count associated with human immunodeficiency virus (HIV) infection. A patient with known Crohn's dis...

journal_title：Journal of clinical gastroenterology

authors： Lautenbach E,Lichtenstein GR

更新日期：1997-09-01 00:00:00

abstract：:The synthesis of prostaglandin E2 (PGE2) and leukotriene B4 (LTB4) in colonic mucosal cells was investigated in 7 patients and 10 controls. Biopsies obtained from the descending colon were isolated biochemically by a special technique and the suspension of isolated colonic cells was incubated during 45 min. Compared w...

journal_title：Journal of clinical gastroenterology

authors： Baumeister B,Schmidt C,Helisch A,Kipnowski J

更新日期：1996-03-01 00:00:00

abstract：:Gastroesophageal varices are a direct consequence of portal hypertension. Nonselective beta-adrenergic blockers decrease portal pressure and are effective in preventing variceal hemorrhage. However, a large multicenter placebo-controlled trial demonstrates that nonselective beta-adrenergic blockers are not effective i...

journal_title：Journal of clinical gastroenterology

authors： Garcia-Tsao G

更新日期：2007-11-01 00:00:00

abstract：:We analyzed retrospectively the characteristics of 87 patients with ulcerative colitis seen in a tertiary care center in north India. Ulcerative colitis was diagnosed on the basis of clinical features, sigmoidoscopy, rectal biopsy, and exclusion of microbiological causes of colitis. Severe clinical disease was seen in...

journal_title：Journal of clinical gastroenterology

authors： Duphare H,Misra SC,Patnaik PK,Mathur M,Tandon RK

更新日期：1994-01-01 00:00:00

abstract：OBJECTIVE:JC virus (JCV) is thought to infect approximately 80% of the human population. Antibodies against JCV can be found in the sera of many people with and without colorectal carcinoma (CRC). We hypothesized that JCV antibody titer will be higher in CRC patients than in healthy controls. AIM:To evaluate this hypo...

journal_title：Journal of clinical gastroenterology

authors： Niv Y,Vilkin A,Levi Z

更新日期：2010-08-01 00:00:00

abstract：:Gastrin stimulates the growth of some human colon adenocarcinomas grown in vitro or as xenografts in nude mice. To evaluate the possibility of elevated plasma gastrin levels in patients with adenomatous polyps or colorectal cancer, we carried out a radioimmunoassay in subjects fasting overnight and undergoing colonosc...

journal_title：Journal of clinical gastroenterology

authors： Seitz JF,Giovannini M,Gouvernet J,Gauthier AP

更新日期：1991-10-01 00:00:00

abstract：:We undertook a 12-year review of the elective and emergency surgery for duodenal ulcer in Queen Mary Hospital, Hong Kong, to ascertain whether the introduction of cimetidine as treatment for duodenal ulcer had led to a reduction in the number of elective and emergency operations being performed for duodenal ulcer. The...

journal_title：Journal of clinical gastroenterology

authors： Alagaratnam TT,Wong J

更新日期：1988-02-01 00:00:00

abstract：:Forty-two patients underwent flexible sigmoidoscopy in the radiology department. After maximal insertion of the sigmoidoscope, a supine abdominal film documented the position of the tip of the instrument. Correlation with barium enema in all patients determined the extent of visualization of the colon relative to the ...

journal_title：Journal of clinical gastroenterology

authors： Ott DJ,Wu WC,Gelfand DW

更新日期：1982-08-01 00:00:00

abstract：:A 35-year-old man developed leg edema, marked hypoalbuminemia, and proteinuria. Subsequent renal biopsy revealed a diffuse membranoproliferative glomerulonephritis and, on electron microscopy, typical electron-dense deposits characteristic of an immune complex pathogenesis. Although protein wasting might have readily ...

journal_title：Journal of clinical gastroenterology

authors： Scholey J,Freeman HJ

更新日期：1986-04-01 00:00:00

abstract：:We describe a 33-year-old man with giant hypertrophic gastropathy (Menetrier's disease), which, on operative biopsy of the stomach, showed a significant inflammatory component. The patient was treated with prednisone and quickly responded. Although a review of the literature revealed only two cases similarly treated, ...

journal_title：Journal of clinical gastroenterology

authors： Davis GE,O'Rourke MC,Metz JR,Kindig WV,Sweeney JG,Kane KN

更新日期：1991-08-01 00:00:00

abstract：GOALS:To review the published experience with acute pancreatitis in childhood. STUDY:Computerized search of the English medical literature since 1965 using MEDLINE. RESULTS:Details of 589 patients were reviewed. Mean age was 9.2 +/- 2.4 years (range: 1 week to 21 years). Male to female ratio was 1.2. Etiologies inclu...

journal_title：Journal of clinical gastroenterology

authors： Benifla M,Weizman Z

更新日期：2003-08-01 00:00:00

abstract：GOALS:Our objective was to determine whether high serologic IgA tissue transglutaminase antibodies (TTGA) are exclusively associated with celiac disease (CD). BACKGROUND:IgA TTGA are found in the serum of most individuals with CD. This serologic marker is used to screen individuals with suspected CD for duodenal biops...

journal_title：Journal of clinical gastroenterology

authors： Donaldson MR,Book LS,Leiferman KM,Zone JJ,Neuhausen SL

更新日期：2008-03-01 00:00:00

abstract：BACKGROUND:Hypoxic hepatitis (HH) occurring after gastrointestinal bleeding in cirrhotic patients has been scarcely studied and is reported as a rare occurrence carrying a severe prognosis. The management of bleeding from esophageal varices (BEV) and similarly the prognosis has improved in the last decades. GOALS:To e...

journal_title：Journal of clinical gastroenterology

authors： Amitrano L,Guardascione MA,Martino R,Manguso F,Menchise A,Balzano A

更新日期：2012-08-01 00:00:00

abstract：:Barrett's esophagus is a common premalignant condition that predisposes to the development of adenocarcinoma of the esophagus through a process of transformation from metaplasia to dysplasia and then carcinoma. Periodic endoscopic surveillance with multiple biopsies is adopted by most physicians to detect dysplasia or...

journal_title：Journal of clinical gastroenterology

authors： Hsu CW,Krevsky B,Sigman LM,Thomas RM

更新日期：1998-10-01 00:00:00

abstract：:Despite the successful FDA approval of sorafenib as the standard of care therapy in patients with advanced hepatocellular carcinoma (HCC), its clinical benefits have been modest. The mortality rate remains high and prognosis poor for patients with advanced-stage HCC. The exact mechanism of sorafenib in the treatment o...

journal_title：Journal of clinical gastroenterology

authors： Lee JK,Abou-Alfa GK

更新日期：2013-07-01 00:00:00

abstract：:A patient with Crohn's disease developed acute pancreatitis 4 h after retaking one 50 mg dose of orally administered 6-mercaptopurine (6-MP). All seven previously reported patients who were rechallenged with 50 mg or more of 6-MP developed pancreatitis within 48 h. These findings suggest that 6-MP can produce pancreat...

journal_title：Journal of clinical gastroenterology

authors： Cappell MS,Das KM

更新日期：1989-12-01 00:00:00