Fine-needle aspiration cytology of the breast in a case with abundant acellular calcific material indicative of soft-tissue calcinosis.

Abstract:

:Since calcific deposits in soft tissue may clinically resemble a tumor, it is feasible to investigate them by fine-needle aspiration (FNA) cytology. In this presentation we describe a case in the breast with extensive accumulation of acellular liquid calcific material which was sampled by the noninvasive technique of FNA, and which was indicative of nonfamilial soft-tissue calcinosis. A 48-yr-old, perimenopausal woman on a routine mammogram showed a well-defined, 1-cm partially cystic opacity in the left upper quadrant of the breast. All other investigations were normal, and no significant family or medical history was present. Under ultrasound guidance FNA was done, and about 1 ml of thick whitish fluid was obtained. Cytopreparations only showed abundant acellular calcium. The patient refused any further treatment and elected to be under the care of her family physician, according to whom she was clinically well with no changes in mammograms for the last 2 yr. The case is interesting, since the cytohistologic findings in aspirate sample appeared to be strongly indicative of soft-tissue calcinosis, which to our knowledge has not been previously reported.

journal_name

Diagn Cytopathol

journal_title

Diagnostic cytopathology

authors

Gupta RK,Naran S,Lallu S,Fauck R,Gaskell D

doi

10.1002/(sici)1097-0339(200001)22:1<30::aid-dc9>3.

subject

Has Abstract

pub_date

2000-01-01 00:00:00

pages

30-2

issue

1

eissn

8755-1039

issn

1097-0339

pii

10.1002/(SICI)1097-0339(200001)22:1<30::AID-DC9>3.

journal_volume

22

pub_type

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