Abstract:
:The publication of guidelines calling for less aggressive treatment of jaundice in newborns has been followed by a reappearance of case reports of kernicterus. These case reports illustrate important issues for writers and consumers of practice guidelines. One issue is the particular salience of identified patients with bad outcomes, and their potentially disproportionate influence on decision-makers. A second issue is whether, when good evidence of treatment benefit is lacking, policymakers should recommend what has traditionally been done, recommend less treatment, or not make recommendations at all. Finally, the cases raise the question of whether treatment guidelines should be more conservative than their authors actually believe is necessary, to take into account the likelihood that they will not be closely followed. We believe that case reports can serve as an important early warning system, but policymakers should be aware of their potentially disproportionate influence. In the long run, patients and clinicians will be best served by guidelines that summarize and acknowledge the limitations of existing evidence, that allow a wide range of treatment options when evidence is weak, and that recommend what the guideline authors actually believe should be done. In the short run a period of readjustment may be required, however, as clinicians become accustomed to guidelines written to be followed, rather than bent.
journal_name
Pediatricsjournal_title
Pediatricsauthors
Newman TB,Maisels MJsubject
Has Abstractpub_date
2000-01-01 00:00:00pages
242-5issue
1 Pt 3eissn
0031-4005issn
1098-4275journal_volume
105pub_type
杂志文章相关文献
PEDIATRICS文献大全abstract:OBJECTIVES:Inadequate sleep during infancy is associated with adverse outcomes for infants and families. We sought to improve sleep behaviors and duration through a responsive parenting (RP) intervention designed for obesity prevention. METHODS:The Intervention Nurses Start Infants Growing on Healthy Trajectories (INS...
journal_title:Pediatrics
pub_type: 杂志文章,随机对照试验
doi:10.1542/peds.2016-0762
更新日期:2016-07-01 00:00:00
abstract::Coma, tetany, dehydration, hypotension, tachycardia, and hyperpyrexia developed in a 2 1/2-year-old girl following two hypertonic phosphate pediatric enemas. She had marked hyperphosphatemia, hypocalcemia, hypernatremia, and acidosis. Hypocalcemia due to hyperphosphatemia can explain all of these findings. Calculation...
journal_title:Pediatrics
pub_type: 杂志文章
doi:
更新日期:1977-09-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to determine whether learning and school problems in extremely low birth weight (ELBW) and reference children differ between cohorts in different countries. METHODS:Participants were 4 international population-based cohorts of ELBW survivors who were 500 to 1000 g birth weight from ...
journal_title:Pediatrics
pub_type: 杂志文章,多中心研究
doi:10.1542/peds.112.4.943
更新日期:2003-10-01 00:00:00
abstract:BACKGROUND:Gender-incongruent (GI) youth have high rates of mental health problems. Although gender-affirming medical care (GAMC) provides psychological benefit, some GI youth present to care at older ages. Whether a relationship exists between age of presentation to GAMC and mental health difficulties warrants study. ...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2019-3600
更新日期:2020-10-01 00:00:00
abstract::One hundred children with the hyperkinetic syndrome or minimal brain dysfunction syndrome were treated with medication: 60 with methylphenidate (Ritalin), 24 with dextroamphetamine (Dexedrine), and 16 with either imipramine or desipramine. The duration of treatment was for a minimum of two years, and averaged five yea...
journal_title:Pediatrics
pub_type: 杂志文章
doi:
更新日期:1976-09-01 00:00:00
abstract::Whether a component of a disease process, the result of acute injury, or a product of a diagnostic or therapeutic procedure, pain should be relieved and stress should be decreased for pediatric patients. Control of pain and stress for children who enter into the emergency medical system, from the prehospital arena to ...
journal_title:Pediatrics
pub_type: 指南,杂志文章,实务指引
doi:10.1542/peds.2004-1752
更新日期:2004-11-01 00:00:00
abstract::A sample of 90 children with Down's syndrome were measured for recumbent length and weight from birth to age 36 months at the Children's Hospital Medical Center in Boston. At birth, means for both length and weight were reduced by about 0.5 SDs from the control group means. By 36 months, mean recumbent length was grea...
journal_title:Pediatrics
pub_type: 杂志文章
doi:
更新日期:1978-04-01 00:00:00
abstract::To test the efficacy and safety of vitamin E in preventing retinopathy of prematurity, 287 infants with birth weights of less than 1.5 kg or gestational ages of less than 33 weeks were enrolled within 24 hours of birth in a randomized, double-masked trial of IV, followed by oral, placebo v tocopherol (adjusted to plas...
journal_title:Pediatrics
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1987-04-01 00:00:00
abstract::Acute febrile neutrophilic dermatosis (Sweet syndrome) is rare in children and is regularly associated with underlying malignancies or inflammtory diseases. A 5-year-old girl with glycogen storage disease type Ib, neutropenia, and recurrent infections developed characteristic skin eruption of Sweet syndrome after 2 ye...
journal_title:Pediatrics
pub_type: 杂志文章
doi:
更新日期:1996-03-01 00:00:00
abstract::The adjustment of children with cystic fibrosis as rated by parents and teachers was compared to that of physically healthy siblings, normal children, and other chronically ill children. The findings indicated that children with cystic fibrosis achieved an age-adequate level of adjustment at home and school. Adjustmen...
journal_title:Pediatrics
pub_type: 杂志文章
doi:
更新日期:1981-03-01 00:00:00
abstract::Hereditary angioedema due to C1 inhibitor deficiency (C1-INH-HAE) is a rare genetic disease that causes recurrent swelling attacks that may affect various body tissues. Angioedematous attacks can be fatal in the case of upper airway edema and are often preceded by prodromal symptoms like erythema marginatum. Initial s...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2015-2411
更新日期:2016-02-01 00:00:00
abstract:OBJECTIVE:We have used the combination of midazolam, a short-acting benzodiazepine, and ketamine, a "dissociative anesthetic," to provide conscious sedation for invasive or lengthy procedures. METHODS:A total of 350 procedures (74 lumbar punctures, 97 bone marrow aspirations or biopsies, 84 radiotherapy sessions, and ...
journal_title:Pediatrics
pub_type: 临床试验,评论,杂志文章
doi:10.1542/peds.99.3.427
更新日期:1997-03-01 00:00:00
abstract:BACKGROUND:Continuous noninvasive monitoring of arterial carbon dioxide (CO2) in neonatal intensive care unit (NICU) patients would help clinicians avoid complications of hypocarbia and hypercarbia. End-tidal CO2 monitoring has not been used in this population to date, but recent technical advances and the introduction...
journal_title:Pediatrics
pub_type: 临床试验,杂志文章
doi:10.1542/peds.101.4.648
更新日期:1998-04-01 00:00:00
abstract:OBJECTIVES:Incomplete subspecialty referrals, whether unscheduled or unattended, represent unmet patient needs and an opportunity to improve patient safety and experiences. Our objectives were to describe the rates of appointment scheduling and visit attendance after pediatric subspecialty referral and to examine patie...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2019-0545
更新日期:2019-12-01 00:00:00
abstract::Psychogenic seizures in 21 nonepileptic children and adolescents, aged 8 to 18 (mean 14.5) years, were recorded by means of video recording and electroencephalography. The episodes included thrashing movements, limb jerking, or staring, with unresponsiveness. Ictal and interictal electroencephalograms showed no abnorm...
journal_title:Pediatrics
pub_type: 杂志文章
doi:
更新日期:1990-04-01 00:00:00
abstract:BACKGROUND:On July 1, 2009, in Ontario the maximum period of continuous duty that residents were permitted to work was reduced from 28 to 24 hours. We evaluated the effect of regulation on residents in 3 eras: 2 before (2005 and early 2009) and 1 after (late 2009) the duty-hour reduction. METHODS:On-call pediatric res...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2010-1955
更新日期:2011-06-01 00:00:00
abstract:OBJECTIVE:Although vision screening for preschool children is recommended for detecting amblyopia, many pediatric and family medicine practices do not screen preschool-aged children. The aim of this study was to determine the effect of a training program for primary care clinical staff on vision screening behavior and ...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.112.1.e17
更新日期:2003-07-01 00:00:00
abstract:OBJECTIVE:To examine factors associated with the maternal perception of the weight status in related and unrelated children and to examine whether associated health risks for children's physical and mental health are recognized. PATIENTS AND METHODS:Two hundred nineteen mothers with children between 3 and 6 years of a...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2008-1845
更新日期:2009-07-01 00:00:00
abstract:OBJECTIVE:Drug trafficking among adolescents is a newly recognized high-risk behavior that seems to be involving large numbers of youths. Strategies to prevent and/or alter this behavior must be developed and evaluated. In view of the high exposure of adolescents to the mass media, interventionists seeking to reduce ad...
journal_title:Pediatrics
pub_type: 杂志文章,评审
doi:
更新日期:1994-06-01 00:00:00
abstract::A total of 322 physicians, Board-certified in pediatric hematology, responded to a survey designed to determine several aspects of their management of children with acute idiopathic thrombocytopenic purpura. The survey demonstrates that, in practice among specialists, a controversy exists as to whether or not bone mar...
journal_title:Pediatrics
pub_type: 杂志文章
doi:
更新日期:1986-01-01 00:00:00
abstract::Advancements in videoconferencing equipment and Internet-based tools for sharing information have resulted in widespread use of telemedicine for providing health care to people who live in remote areas. Given the limited supply of people trained to provide early-intervention services to infants and young children who ...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2010-0354J
更新日期:2010-08-01 00:00:00
abstract:OBJECTIVE:The frequency of children who are hospitalized with pneumococcal pneumonia complicated by necrosis, empyema/complicated parapneumonic effusion, and lung abscess seems to be increasing. The factors that contribute to this increase are unclear; therefore, the objective of this study was to describe and compare ...
journal_title:Pediatrics
pub_type: 杂志文章,多中心研究
doi:10.1542/peds.110.1.1
更新日期:2002-07-01 00:00:00
abstract:OBJECTIVES:Hutchinson-Gilford progeria syndrome is a rare and uniformly fatal segmental "premature aging" disease that affects a variety of organ systems. We sought to more clearly define the bone and weight abnormalities in patients with progeria as potential outcome parameters for prospective clinical trials. PATIEN...
journal_title:Pediatrics
pub_type: 杂志文章,多中心研究
doi:10.1542/peds.2007-1357
更新日期:2007-10-01 00:00:00
abstract:OBJECTIVE:To assess measures of puberty-presence of pubic hair, breast development, and menarche-for 3 racial/ethnic groups of girls in the United States. METHODS:Using data from the Third National Health and Nutrition Examination Survey, this study sample was restricted to 1623 girls aged 8 to 16 years (466 non-Hispa...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.110.4.752
更新日期:2002-10-01 00:00:00
abstract::The sequence of events leading to the development of acute obstruction in two infants with coarctation has been defined by clinical, hemodynamic, and angiographic studies. One infant had normally related great arteries and an isolated coarctation, while the other infant had transposition with a hypoplastic right ventr...
journal_title:Pediatrics
pub_type: 杂志文章
doi:
更新日期:1975-10-01 00:00:00
abstract:BACKGROUND:Respiratory syncytial virus (RSV) is a common reason for hospitalization of infants. In clinical trials, palivizumab reduced RSV hospitalization rates for premature infants. The 2014 American Academy of Pediatrics clinical practice guideline advised against use of palivizumab for otherwise healthy infants ≥2...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2016-0627
更新日期:2016-08-01 00:00:00
abstract:OBJECTIVE:High rates of use of child safety seats have been achieved. A remaining challenge in child passenger safety is to reach the Healthy People 2010 objective of child safety seat use to 100%. Several factors have been reported to influence child safety seat use. A child safety seat Hassles Scale was developed to ...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2005-2211
更新日期:2006-07-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:The increase in neonatal abstinence syndrome (NAS) has underscored the need for NAS surveillance programs, but many rely on passive surveillance using unverified diagnosis codes. Few studies have evaluated the validity of these codes, and no study has assessed the recently proposed Council of ...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2020-0567
更新日期:2020-09-01 00:00:00
abstract:OBJECTIVE:The goal was to examine the association between violence in the media and the expression of seriously violent behavior among older children and teenagers in a national sample. METHODS:The Growing up with Media survey was a national, online survey of 1588 youths that was conducted in August and September 2006...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2007-3377
更新日期:2008-11-01 00:00:00
abstract::This clinical report defines common terms of use and provides information on current practice, research, and limitations of assistive technology that can be used in systems for communication. The assessment process to determine the best devices for use with a particular child (ie, the best fit of a device) is also rev...
journal_title:Pediatrics
pub_type: 杂志文章,实务指引
doi:10.1542/peds.2008-0695
更新日期:2008-06-01 00:00:00