Less aggressive treatment of neonatal jaundice and reports of kernicterus: lessons about practice guidelines.

Abstract:

:The publication of guidelines calling for less aggressive treatment of jaundice in newborns has been followed by a reappearance of case reports of kernicterus. These case reports illustrate important issues for writers and consumers of practice guidelines. One issue is the particular salience of identified patients with bad outcomes, and their potentially disproportionate influence on decision-makers. A second issue is whether, when good evidence of treatment benefit is lacking, policymakers should recommend what has traditionally been done, recommend less treatment, or not make recommendations at all. Finally, the cases raise the question of whether treatment guidelines should be more conservative than their authors actually believe is necessary, to take into account the likelihood that they will not be closely followed. We believe that case reports can serve as an important early warning system, but policymakers should be aware of their potentially disproportionate influence. In the long run, patients and clinicians will be best served by guidelines that summarize and acknowledge the limitations of existing evidence, that allow a wide range of treatment options when evidence is weak, and that recommend what the guideline authors actually believe should be done. In the short run a period of readjustment may be required, however, as clinicians become accustomed to guidelines written to be followed, rather than bent.

journal_name

Pediatrics

journal_title

Pediatrics

authors

Newman TB,Maisels MJ

subject

Has Abstract

pub_date

2000-01-01 00:00:00

pages

242-5

issue

1 Pt 3

eissn

0031-4005

issn

1098-4275

journal_volume

105

pub_type

杂志文章
  • INSIGHT Responsive Parenting Intervention and Infant Sleep.

    abstract:OBJECTIVES:Inadequate sleep during infancy is associated with adverse outcomes for infants and families. We sought to improve sleep behaviors and duration through a responsive parenting (RP) intervention designed for obesity prevention. METHODS:The Intervention Nurses Start Infants Growing on Healthy Trajectories (INS...

    journal_title:Pediatrics

    pub_type: 杂志文章,随机对照试验

    doi:10.1542/peds.2016-0762

    authors: Paul IM,Savage JS,Anzman-Frasca S,Marini ME,Mindell JA,Birch LL

    更新日期:2016-07-01 00:00:00

  • Hypocalcemic coma following two pediatric phosphate enemas.

    abstract::Coma, tetany, dehydration, hypotension, tachycardia, and hyperpyrexia developed in a 2 1/2-year-old girl following two hypertonic phosphate pediatric enemas. She had marked hyperphosphatemia, hypocalcemia, hypernatremia, and acidosis. Hypocalcemia due to hyperphosphatemia can explain all of these findings. Calculation...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:

    authors: Sotos JF,Cutler EA,Finkel MA,Doody D

    更新日期:1977-09-01 00:00:00

  • School-age outcomes in children who were extremely low birth weight from four international population-based cohorts.

    abstract:OBJECTIVE:The aim of this study was to determine whether learning and school problems in extremely low birth weight (ELBW) and reference children differ between cohorts in different countries. METHODS:Participants were 4 international population-based cohorts of ELBW survivors who were 500 to 1000 g birth weight from ...

    journal_title:Pediatrics

    pub_type: 杂志文章,多中心研究

    doi:10.1542/peds.112.4.943

    authors: Saigal S,den Ouden L,Wolke D,Hoult L,Paneth N,Streiner DL,Whitaker A,Pinto-Martin J

    更新日期:2003-10-01 00:00:00

  • Mental Health and Timing of Gender-Affirming Care.

    abstract:BACKGROUND:Gender-incongruent (GI) youth have high rates of mental health problems. Although gender-affirming medical care (GAMC) provides psychological benefit, some GI youth present to care at older ages. Whether a relationship exists between age of presentation to GAMC and mental health difficulties warrants study. ...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2019-3600

    authors: Sorbara JC,Chiniara LN,Thompson S,Palmert MR

    更新日期:2020-10-01 00:00:00

  • Growth of hyperkinetic children taking methylphenidate, dextroamphetamine, or imipramine/desipramine.

    abstract::One hundred children with the hyperkinetic syndrome or minimal brain dysfunction syndrome were treated with medication: 60 with methylphenidate (Ritalin), 24 with dextroamphetamine (Dexedrine), and 16 with either imipramine or desipramine. The duration of treatment was for a minimum of two years, and averaged five yea...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:

    authors: Gross MD

    更新日期:1976-09-01 00:00:00

  • Relief of pain and anxiety in pediatric patients in emergency medical systems.

    abstract::Whether a component of a disease process, the result of acute injury, or a product of a diagnostic or therapeutic procedure, pain should be relieved and stress should be decreased for pediatric patients. Control of pain and stress for children who enter into the emergency medical system, from the prehospital arena to ...

    journal_title:Pediatrics

    pub_type: 指南,杂志文章,实务指引

    doi:10.1542/peds.2004-1752

    authors: Zempsky WT,Cravero JP,American Academy of Pediatrics Committee on Pediatric Emergency Medicine and Section on Anesthesiology and Pain Medicine.

    更新日期:2004-11-01 00:00:00

  • Growth of children with Down's syndrome: birth to age 3 years.

    abstract::A sample of 90 children with Down's syndrome were measured for recumbent length and weight from birth to age 36 months at the Children's Hospital Medical Center in Boston. At birth, means for both length and weight were reduced by about 0.5 SDs from the control group means. By 36 months, mean recumbent length was grea...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:

    authors: Cronk CE

    更新日期:1978-04-01 00:00:00

  • Tocopherol efficacy and safety for preventing retinopathy of prematurity: a randomized, controlled, double-masked trial.

    abstract::To test the efficacy and safety of vitamin E in preventing retinopathy of prematurity, 287 infants with birth weights of less than 1.5 kg or gestational ages of less than 33 weeks were enrolled within 24 hours of birth in a randomized, double-masked trial of IV, followed by oral, placebo v tocopherol (adjusted to plas...

    journal_title:Pediatrics

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:

    authors: Phelps DL,Rosenbaum AL,Isenberg SJ,Leake RD,Dorey FJ

    更新日期:1987-04-01 00:00:00

  • Sweet syndrome associated with G-CSF treatment in a child with glycogen storage disease type Ib.

    abstract::Acute febrile neutrophilic dermatosis (Sweet syndrome) is rare in children and is regularly associated with underlying malignancies or inflammtory diseases. A 5-year-old girl with glycogen storage disease type Ib, neutropenia, and recurrent infections developed characteristic skin eruption of Sweet syndrome after 2 ye...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:

    authors: Garty BZ,Levy I,Nitzan M,Barak Y

    更新日期:1996-03-01 00:00:00

  • Psychosocial functioning of children with cystic fibrosis.

    abstract::The adjustment of children with cystic fibrosis as rated by parents and teachers was compared to that of physically healthy siblings, normal children, and other chronically ill children. The findings indicated that children with cystic fibrosis achieved an age-adequate level of adjustment at home and school. Adjustmen...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:

    authors: Drotar D,Doershuk CF,Stern RC,Boat TF,Boyer W,Matthews L

    更新日期:1981-03-01 00:00:00

  • Erythema Marginatum as an Early Symptom of Hereditary Angioedema: Case Report of 2 Newborns.

    abstract::Hereditary angioedema due to C1 inhibitor deficiency (C1-INH-HAE) is a rare genetic disease that causes recurrent swelling attacks that may affect various body tissues. Angioedematous attacks can be fatal in the case of upper airway edema and are often preceded by prodromal symptoms like erythema marginatum. Initial s...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2015-2411

    authors: Martinez-Saguer I,Farkas H

    更新日期:2016-02-01 00:00:00

  • Efficacy and safety of intravenous midazolam and ketamine as sedation for therapeutic and diagnostic procedures in children.

    abstract:OBJECTIVE:We have used the combination of midazolam, a short-acting benzodiazepine, and ketamine, a "dissociative anesthetic," to provide conscious sedation for invasive or lengthy procedures. METHODS:A total of 350 procedures (74 lumbar punctures, 97 bone marrow aspirations or biopsies, 84 radiotherapy sessions, and ...

    journal_title:Pediatrics

    pub_type: 临床试验,评论,杂志文章

    doi:10.1542/peds.99.3.427

    authors: Parker RI,Mahan RA,Giugliano D,Parker MM

    更新日期:1997-03-01 00:00:00

  • Mainstream end-tidal carbon dioxide monitoring in the neonatal intensive care unit.

    abstract:BACKGROUND:Continuous noninvasive monitoring of arterial carbon dioxide (CO2) in neonatal intensive care unit (NICU) patients would help clinicians avoid complications of hypocarbia and hypercarbia. End-tidal CO2 monitoring has not been used in this population to date, but recent technical advances and the introduction...

    journal_title:Pediatrics

    pub_type: 临床试验,杂志文章

    doi:10.1542/peds.101.4.648

    authors: Rozycki HJ,Sysyn GD,Marshall MK,Malloy R,Wiswell TE

    更新日期:1998-04-01 00:00:00

  • Unscheduled Referrals and Unattended Appointments After Pediatric Subspecialty Referral.

    abstract:OBJECTIVES:Incomplete subspecialty referrals, whether unscheduled or unattended, represent unmet patient needs and an opportunity to improve patient safety and experiences. Our objectives were to describe the rates of appointment scheduling and visit attendance after pediatric subspecialty referral and to examine patie...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2019-0545

    authors: Bohnhoff JC,Taormina JM,Ferrante L,Wolfson D,Ray KN

    更新日期:2019-12-01 00:00:00

  • Psychogenic seizures in children and adolescents: outcome after diagnosis by ictal video and electroencephalographic recording.

    abstract::Psychogenic seizures in 21 nonepileptic children and adolescents, aged 8 to 18 (mean 14.5) years, were recorded by means of video recording and electroencephalography. The episodes included thrashing movements, limb jerking, or staring, with unresponsiveness. Ictal and interictal electroencephalograms showed no abnorm...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:

    authors: Wyllie E,Friedman D,Rothner AD,Luders H,Dinner D,Morris H 3rd,Cruse R,Erenberg G,Kotagal P

    更新日期:1990-04-01 00:00:00

  • Prospective evaluation of residents on call: before and after duty-hour reduction.

    abstract:BACKGROUND:On July 1, 2009, in Ontario the maximum period of continuous duty that residents were permitted to work was reduced from 28 to 24 hours. We evaluated the effect of regulation on residents in 3 eras: 2 before (2005 and early 2009) and 1 after (late 2009) the duty-hour reduction. METHODS:On-call pediatric res...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2010-1955

    authors: Bismilla Z,Breakey VR,Swales J,Kulik DM,Pai N,Singh N,Parshuram CS

    更新日期:2011-06-01 00:00:00

  • Preschool vision screening frequency after an office-based training session for primary care staff.

    abstract:OBJECTIVE:Although vision screening for preschool children is recommended for detecting amblyopia, many pediatric and family medicine practices do not screen preschool-aged children. The aim of this study was to determine the effect of a training program for primary care clinical staff on vision screening behavior and ...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.112.1.e17

    authors: Hered RW,Rothstein M

    更新日期:2003-07-01 00:00:00

  • Maternal perception of weight status and health risks associated with obesity in children.

    abstract:OBJECTIVE:To examine factors associated with the maternal perception of the weight status in related and unrelated children and to examine whether associated health risks for children's physical and mental health are recognized. PATIENTS AND METHODS:Two hundred nineteen mothers with children between 3 and 6 years of a...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2008-1845

    authors: Warschburger P,Kröller K

    更新日期:2009-07-01 00:00:00

  • Using mass media to reduce adolescent involvement in drug trafficking.

    abstract:OBJECTIVE:Drug trafficking among adolescents is a newly recognized high-risk behavior that seems to be involving large numbers of youths. Strategies to prevent and/or alter this behavior must be developed and evaluated. In view of the high exposure of adolescents to the mass media, interventionists seeking to reduce ad...

    journal_title:Pediatrics

    pub_type: 杂志文章,评审

    doi:

    authors: Romer D

    更新日期:1994-06-01 00:00:00

  • Controversies in the management of acute idiopathic thrombocytopenic purpura: a survey of specialists.

    abstract::A total of 322 physicians, Board-certified in pediatric hematology, responded to a survey designed to determine several aspects of their management of children with acute idiopathic thrombocytopenic purpura. The survey demonstrates that, in practice among specialists, a controversy exists as to whether or not bone mar...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:

    authors: Dubansky AS,Oski FA

    更新日期:1986-01-01 00:00:00

  • Teleintervention for infants and young children who are deaf or hard-of-hearing.

    abstract::Advancements in videoconferencing equipment and Internet-based tools for sharing information have resulted in widespread use of telemedicine for providing health care to people who live in remote areas. Given the limited supply of people trained to provide early-intervention services to infants and young children who ...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2010-0354J

    authors: McCarthy M,Muñoz K,White KR

    更新日期:2010-08-01 00:00:00

  • Clinical characteristics of children with complicated pneumonia caused by Streptococcus pneumoniae.

    abstract:OBJECTIVE:The frequency of children who are hospitalized with pneumococcal pneumonia complicated by necrosis, empyema/complicated parapneumonic effusion, and lung abscess seems to be increasing. The factors that contribute to this increase are unclear; therefore, the objective of this study was to describe and compare ...

    journal_title:Pediatrics

    pub_type: 杂志文章,多中心研究

    doi:10.1542/peds.110.1.1

    authors: Tan TQ,Mason EO Jr,Wald ER,Barson WJ,Schutze GE,Bradley JS,Givner LB,Yogev R,Kim KS,Kaplan SL

    更新日期:2002-07-01 00:00:00

  • Disease progression in Hutchinson-Gilford progeria syndrome: impact on growth and development.

    abstract:OBJECTIVES:Hutchinson-Gilford progeria syndrome is a rare and uniformly fatal segmental "premature aging" disease that affects a variety of organ systems. We sought to more clearly define the bone and weight abnormalities in patients with progeria as potential outcome parameters for prospective clinical trials. PATIEN...

    journal_title:Pediatrics

    pub_type: 杂志文章,多中心研究

    doi:10.1542/peds.2007-1357

    authors: Gordon LB,McCarten KM,Giobbie-Hurder A,Machan JT,Campbell SE,Berns SD,Kieran MW

    更新日期:2007-10-01 00:00:00

  • Ethnic differences in the presence of secondary sex characteristics and menarche among US girls: the Third National Health and Nutrition Examination Survey, 1988-1994.

    abstract:OBJECTIVE:To assess measures of puberty-presence of pubic hair, breast development, and menarche-for 3 racial/ethnic groups of girls in the United States. METHODS:Using data from the Third National Health and Nutrition Examination Survey, this study sample was restricted to 1623 girls aged 8 to 16 years (466 non-Hispa...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.110.4.752

    authors: Wu T,Mendola P,Buck GM

    更新日期:2002-10-01 00:00:00

  • Postnatal development of obstruction in coarctation of the aorta: role of the ductus arteriosus.

    abstract::The sequence of events leading to the development of acute obstruction in two infants with coarctation has been defined by clinical, hemodynamic, and angiographic studies. One infant had normally related great arteries and an isolated coarctation, while the other infant had transposition with a hypoplastic right ventr...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:

    authors: Talner NS,Berman MA

    更新日期:1975-10-01 00:00:00

  • Observed Effectiveness of Palivizumab for 29-36-Week Gestation Infants.

    abstract:BACKGROUND:Respiratory syncytial virus (RSV) is a common reason for hospitalization of infants. In clinical trials, palivizumab reduced RSV hospitalization rates for premature infants. The 2014 American Academy of Pediatrics clinical practice guideline advised against use of palivizumab for otherwise healthy infants ≥2...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2016-0627

    authors: Farber HJ,Buckwold FJ,Lachman B,Simpson JS,Buck E,Arun M,Valadez AM,Ruiz T,Alonzo J,Henry A,Cos-Okpalla N,Nguyen K,Brendel W,Small J,Glomb WB

    更新日期:2016-08-01 00:00:00

  • Development of a child safety seat Hassles Scale in a largely low-income Latino population.

    abstract:OBJECTIVE:High rates of use of child safety seats have been achieved. A remaining challenge in child passenger safety is to reach the Healthy People 2010 objective of child safety seat use to 100%. Several factors have been reported to influence child safety seat use. A child safety seat Hassles Scale was developed to ...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2005-2211

    authors: Agran PF,Anderson C,Winn DG

    更新日期:2006-07-01 00:00:00

  • Diagnosis Codes and Case Definitions for Neonatal Abstinence Syndrome.

    abstract:BACKGROUND AND OBJECTIVES:The increase in neonatal abstinence syndrome (NAS) has underscored the need for NAS surveillance programs, but many rely on passive surveillance using unverified diagnosis codes. Few studies have evaluated the validity of these codes, and no study has assessed the recently proposed Council of ...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2020-0567

    authors: Elmore AL,Tanner JP,Lowry J,Lake-Burger H,Kirby RS,Hudak ML,Sappenfield WM,Salemi JL

    更新日期:2020-09-01 00:00:00

  • Linkages between internet and other media violence with seriously violent behavior by youth.

    abstract:OBJECTIVE:The goal was to examine the association between violence in the media and the expression of seriously violent behavior among older children and teenagers in a national sample. METHODS:The Growing up with Media survey was a national, online survey of 1588 youths that was conducted in August and September 2006...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2007-3377

    authors: Ybarra ML,Diener-West M,Markow D,Leaf PJ,Hamburger M,Boxer P

    更新日期:2008-11-01 00:00:00

  • Prescribing assistive-technology systems: focus on children with impaired communication.

    abstract::This clinical report defines common terms of use and provides information on current practice, research, and limitations of assistive technology that can be used in systems for communication. The assessment process to determine the best devices for use with a particular child (ie, the best fit of a device) is also rev...

    journal_title:Pediatrics

    pub_type: 杂志文章,实务指引

    doi:10.1542/peds.2008-0695

    authors: Desch LW,Gaebler-Spira D,Council on Children With Disabilities.

    更新日期:2008-06-01 00:00:00