Social stability attenuates the stress in the modified multiple platform method for paradoxical sleep deprivation in the rat.

Abstract:

:The instrumental methods to induce paradoxical sleep (PS) deprivation are stressful. The modified multiple platform method (MMPM), in which animals are placed with new cohorts inside the water tanks, results in augmented ACTH and corticosterone (CORT) responses. We hypothesised that this increased response could be attributed to social instability. In addition, we tested a new environmental control, a grid (GR) placed on the tank floor. Animals were submitted to the MMPM for 4 days as socially unstable (UG--coming from several cages) or stable groups (SG--coming from one cage), placed either on narrow platforms or on the grid. All UG animals presented higher ACTH levels than their SG counterparts, including home-cage controls. CORT levels of manipulated animals were higher than controls only in the stable group. UG animals presented heavier adrenals than their SG counterparts. Only adrenals from SG animals placed on the grid were similar to cage controls. SG rats lost less weight than UG animals. While UG animals ate the same amount of chow as home-cage controls, SG animals ate more than control and UG animals. These results suggest that the stress of the MMPM can be attenuated in stable groups. The introduction of a grid on the tank floor may serve an adequate environmental control as far as stress-related variables are considered.

journal_name

Physiol Behav

journal_title

Physiology & behavior

authors

Suchecki D,Tufik S

doi

10.1016/s0031-9384(99)00181-x

subject

Has Abstract

pub_date

2000-01-01 00:00:00

pages

309-16

issue

3

eissn

0031-9384

issn

1873-507X

pii

S0031-9384(99)00181-X

journal_volume

68

pub_type

杂志文章
  • Change in the hedonic value of an aversive stimulus in the presence of a pre-exposed odor.

    abstract::Rats exhibit a sensitive period from the time of birth until postnatal day 10 during which they develop preferences for odors even if those odors are paired with a moderately aversive stimulus. It is still unknown whether pre-exposure to an odor produces alterations on intake responses of basic tastants, and on other ...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/j.physbeh.2014.12.041

    authors: Kamenetzky GV,Suárez AB,Pautassi RM,Mustaca AE,Nizhnikov ME

    更新日期:2015-09-01 00:00:00

  • Rats that binge eat fat-rich food do not show somatic signs or anxiety associated with opiate-like withdrawal: implications for nutrient-specific food addiction behaviors.

    abstract::Previous studies suggest that binge eating sugar leads to behavioral and neurochemical changes similar to those seen with drug addiction, including signs of opiate-like withdrawal. Studies are emerging that show multiple neurochemical and behavioral indices of addiction when animals overeat a fat-rich diet. The goal o...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/j.physbeh.2011.05.018

    authors: Bocarsly ME,Berner LA,Hoebel BG,Avena NM

    更新日期:2011-10-24 00:00:00

  • Refeeding after acute food restriction: differential reduction in preference for ethanol and ethanol-paired flavors in selectively bred rats.

    abstract::Rats' voluntary ethanol intake varies with dispositional factors and energy status. The joint influences of these were of interest here. We previously reported that rats selectively bred for high voluntary saccharin intake (HiS) consume more ethanol and express more robust conditioning of preference for flavors paired...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/j.physbeh.2012.12.001

    authors: Dess NK,Chapman CD,Cousins LA,Monroe DC,Nguyen P

    更新日期:2013-01-17 00:00:00

  • Vaginal bacterial flora partially determines sexual attractivity of female rats.

    abstract::This study shows that the bacterial flora of the rat's vagina plays a role in the determination of female sexual attractivity. In the experiment described, the change in attractivity of a female rat was monitored during the estrous cycle by using a residential plus-maze. The time that male rats spent in the vicinity o...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/0031-9384(88)90359-9

    authors: Merkx J,Slob AK,van der Werff ten Bosch JJ

    更新日期:1988-01-01 00:00:00

  • Individual housing from rearing modifies the performance of young rats on the elevated plus-maze apparatus.

    abstract::Previous studies from our laboratory have demonstrated that male and female rats exhibit a differential pattern of behavior in the elevated plus-maze as a function of age. In the present study, the influence of individual housing conditions on young animals treated with one of two classical anxioselective drugs, diaze...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/s0031-9384(96)00254-5

    authors: Da Silva NL,Ferreira VM,Carobrez Ade P,Morato GS

    更新日期:1996-12-01 00:00:00

  • Effects of ability- and chance-determined competition outcome on testosterone.

    abstract::Winning competitions has been shown to lead to higher testosterone (T) relative to losing in men and males of other species. In Experiment 1, 38 women and 37 men provided a saliva sample, completed a novel computer-based vocabulary competition task at which they won or lost based on their own ability, provided feedbac...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/j.physbeh.2006.11.017

    authors: van Anders SM,Watson NV

    更新日期:2007-03-16 00:00:00

  • Chronic immobilization stress reduces sodium intake and renal excretion in rats.

    abstract::The influence of chronic exposure to immobilization (IMO) on sodium appetite as well as sodium and potassium renal excretion in adult male Wistar rats was studied. The animals were individually housed and all variables under observation were measured in metabolic cages the first, seventh, and thirteenth days once the ...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/s0031-9384(97)00197-2

    authors: Bensi N,Bertuzzi M,Armario A,Gauna HF

    更新日期:1997-12-01 00:00:00

  • Antidepressant effect of ingested nicotine in female rats of Flinders resistant and sensitive lines.

    abstract::Both major depression and depressive symptoms are associated with a high rate of nicotine dependence, and a history of major depression has an adverse impact on smoking cessation. The main objective of this study was to investigate whether continuous ingestion of nicotine affects indices of depressive behavior in the ...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/s0031-9384(99)00091-8

    authors: Djurić VJ,Dunn E,Overstreet DH,Dragomir A,Steiner M

    更新日期:1999-10-01 00:00:00

  • Copulatory behavior of sexually naive and sexually experienced male rats following removal of the vomeronasal organ.

    abstract::The question addressed was whether removal of the vomeronasal organ (VNO) of the male rat would produce observable deficits in sexual behavior. Both sexually naive and sexually experienced males were used and each animal was given more than 12 hours to mate with a receptive female. Although sexual arousal was depresse...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/0031-9384(86)90215-5

    authors: Saito TR,Moltz H

    更新日期:1986-01-01 00:00:00

  • Physiological mechanisms mediating patterns of reproductive suppression and alloparental care in cooperatively breeding carnivores.

    abstract::Although cooperation represents a long-standing evolutionary puzzle, field studies on social carnivores have contributed greatly to our understanding of the selective forces favoring cooperative breeding. Despite these insights, our grasp of the proximate mechanisms facilitating cooperation in carnivores remains surpr...

    journal_title:Physiology & behavior

    pub_type: 杂志文章,评审

    doi:10.1016/j.physbeh.2017.11.006

    authors: Montgomery TM,Pendleton EL,Smith JE

    更新日期:2018-09-01 00:00:00

  • Sexual experience with a known male modulates c-Fos expression in response to mating and male pheromone exposure in female mice.

    abstract::Sexually naïve female mice are not sexually receptive in their first mating opportunity. Four to five sexual encounters are needed to display high sexual receptivity as assessed by the lordosis reflex. The neuronal changes induced by sexual experience are not well understood. In this study, we evaluated if repeated se...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/j.physbeh.2020.112906

    authors: Marco-Manclus P,Paredes RG,Portillo W

    更新日期:2020-08-01 00:00:00

  • Medial and lateral amygdalectomy differentially influences consummatory negative contrast.

    abstract::Rats shifted from a 32% to 4% sucrose solution consume substantially less 4% sucrose than unshifted animals that experience only the 4% solution. This negative contrast effect was found to be attenuated by lesions of the lateral aspects of the amygdala (basolateral, lateral, and basomedial nuclei) and eliminated by le...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/0031-9384(84)90035-0

    authors: Becker HC,Jarvis MF,Wagner GC,Flaherty CF

    更新日期:1984-11-01 00:00:00

  • State-dependent learning following electrical stimulation of the hippocampus: intact and split-brain rats.

    abstract::In experiment 1, electrical stimulation of the posterior hippocampus was shown to produce state-dependent learning (SDL) for a step-out inhibitory avoidance task in rats. Stimulation sites in either the right or left hippocampus were equally effective in producing this effect. Similarly, the presence or absence of aft...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/0031-9384(85)90091-5

    authors: McIntyre DC,Stenstrom RJ,Taylor D,Stokes KA,Edson N

    更新日期:1985-01-01 00:00:00

  • Adrenalectomy enhances the anorectic effect of dexfenfluramine: relation to mineralocorticoids and salt appetite.

    abstract::A previous observation that adrenalectomized (ADX) rats were more anorectic and lost more weight than intact controls when treated with the serotonergic agent, d,l-fenfluramine, was confirmed using a high dose of the more selective d-enantiomer, dexfenfluramine (DFEN). However, ADX rats were not more anorectic than in...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/0031-9384(93)90099-2

    authors: Rowland NE,Dotson LM

    更新日期:1993-08-01 00:00:00

  • Effect of sucrose in breakfast items on pleasantness and food intake in the elderly.

    abstract::This study was designed to determine the differences between young and elderly people on the perceived intensity and pleasantness of sucrose in foods, in relation to their food intake. First, a group of 35 young subjects (mean age: 22 +/- 2 years) and 29 elderly subjects (mean age: 79 +/- 6 years) judged the intensity...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/s0031-9384(96)00306-x

    authors: De Jong N,De Graaf C,Van Staveren WA

    更新日期:1996-12-01 00:00:00

  • Effects of cholecystokinin-octapeptide (CCK-8) on food intake and gastric emptying in man.

    abstract::Food intake and gastric emptying were measured simultaneously after cholecystokinin-octapeptide (CCK-8) and saline infusions in order to test the hypothesis that reduction in gastric emptying mediates the effect of CCK-8 on food intake. Each of twelve nonobese healthy men received intravenous infusions of CCK-8 and sa...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/0031-9384(88)90330-7

    authors: Muurahainen N,Kissileff HR,Derogatis AJ,Pi-Sunyer FX

    更新日期:1988-01-01 00:00:00

  • Enhanced voluntary wheel running in GPRC6A receptor knockout mice.

    abstract::GPRC6A is an amino acid-sensing receptor highly expressed in the brain and in skeletal muscle. Although recent evidence suggests that genetically engineered GPRC6A receptor knockout (KO) mice are susceptible to develop subtle endocrine and metabolic disturbances, the underlying disruptions in energy metabolism are lar...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/j.physbeh.2013.05.015

    authors: Clemmensen C,Pehmøller C,Klein AB,Ratner C,Wojtaszewski JF,Bräuner-Osborne H

    更新日期:2013-06-13 00:00:00

  • Impaired drinking to angiotensin II after subdiaphragmatic vagotomy in rats.

    abstract::Rats received total bilateral subdiaphragmatic vagotomy and, one month later, were fitted with chronic intravenous or intracerebroventricular cannulas. The vagotomized rats showed much reduced drinking compared with controls during intravenous infusion of angiotensin II. Their drinking to intracerebroventricularly adm...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/0031-9384(80)90068-2

    authors: Rowland N

    更新日期:1980-06-01 00:00:00

  • Feed pecking in young chickens: new techniques of evaluation.

    abstract::Three techniques were compared: automated recording (A) of 2 h of feeding activities conveyed to a computer by constantly connected electronic balances, videotaping (V) of a closeup of the head of a chick during a feed-pecking session analyzed by focal sampling at reduced speed (16 times slower), strength of pecking (...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/s0031-9384(96)00535-5

    authors: Yo T,Vilariño M,Faure JM,Picard M

    更新日期:1997-06-01 00:00:00

  • Androgen receptors in Purkinje neurons are modulated by systemic testosterone and sexual training in a region-specific manner in the male rat.

    abstract::The androgen receptor (AR) is a widely distributed molecule indicating the spread actions of its ligand steroid, and plays an important role underlying male sexual behavior. Nevertheless, the influence of steroid hormones and their receptors on cerebellar neurons, as foundation of sexual behavior, is largely unknown. ...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/j.physbeh.2016.01.027

    authors: Perez-Pouchoulen M,Toledo R,Garcia LI,Perez-Estudillo CA,Coria-Avila GA,Hernandez ME,Carrillo P,Manzo J

    更新日期:2016-03-15 00:00:00

  • Estradiol decreases the orexigenic effect of melanin-concentrating hormone in ovariectomized rats.

    abstract::Estradiol exerts an inhibitory effect on food intake via interactions with anorexigenic peptides, like cholecystokinin, that function to decrease meal size. It is currently unknown whether estradiol also interacts with orexigenic compounds implicated in the physiological control of food intake. Thus, the primary goal ...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/j.physbeh.2006.05.002

    authors: Messina MM,Boersma G,Overton JM,Eckel LA

    更新日期:2006-07-30 00:00:00

  • Dieting and pain sensitivity: a validation of clinical findings.

    abstract::To validate findings of a reduced pain sensitivity in anorexia and bulimia nervosa, the effects of dieting on somatosensation (especially pain sensitivity) were investigated in healthy young women. One group of subjects (n = 11) received a calorically reduced balanced diet for 21 days, while the other group (n = 14) c...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/0031-9384(91)90557-5

    authors: Lautenbacher S,Barth K,Friess E,Strian F,Pirke KM,Krieg JC

    更新日期:1991-09-01 00:00:00

  • Lever-press conditioning in the crab.

    abstract::An operant chamber has been developed for studying lever-press conditioning in the green crab Carcinus maenas. In one series of experiments, animals were presented with a single bar and were reinforced with food for every bar press. Performance increased over time and high rates of responding were observed after 2 day...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/0031-9384(90)90311-q

    authors: Abramson CI,Feinman RD

    更新日期:1990-08-01 00:00:00

  • Early weaning predisposes rats to exacerbated activity-stress ulcer formation.

    abstract::Rats were weaned early (Day 15), normally (Day 21) or late (Day 27). When they reached 200 g (+/- 10) they were placed into the activity-stress paradigm. Half the rats in each weaning group were housed in activity-wheel cages and fed only 1 hr each day. The remaining rats served as food-yoked home cage controls and we...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/0031-9384(85)90012-5

    authors: Glavin GB,Pare WP

    更新日期:1985-06-01 00:00:00

  • Wrist motion rhythm phase shifts in travelers may differ from changes in time zones.

    abstract::Wrist motions (223-471)/5 min were measured during 17-32 days of continuous recordings made from human passengers as they traveled across zero to five time zones for business and pleasure. The travelers all exhibited daily cycles of activity and rest. The duration of daily activity, alpha, was 1.1 h less at the destin...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/0031-9384(94)90088-4

    authors: Binkley S

    更新日期:1994-05-01 00:00:00

  • Exploring determinants of behavioral chronotype in a diurnal-rodent model of human physiology.

    abstract::Numerous studies conducted with human participants have shown that differences in chronotype, defined as individual patterns of early or late beginning of daily activity, have implications for many biobehavioral processes, such as cognitive performance, mood, impulsivity, academic achievement of college students, and ...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/j.physbeh.2018.11.019

    authors: Refinetti R,Earle G,Kenagy GJ

    更新日期:2019-02-01 00:00:00

  • Cholinergic and GABAergic modulation of self-stimulation of lateral hypothalamus and ventral tegmentum: effects of carbachol, atropine, bicuculline, and picrotoxin.

    abstract::This study aimed at investigating the effects of modulators of acetylcholine-muscarinic (ACh-M) and GABAA.B-receptors in the lateral hypothalamus and ventral tegmentum on the electrical self-stimulation evoked from these regions. In each Wistar rat, a bipolar electrode and an ipsilateral insulated cannula-cum-electrod...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/s0031-9384(96)00452-0

    authors: Singh J,Desiraju T,Raju TR

    更新日期:1997-03-01 00:00:00

  • Stripes disrupt odour attractiveness to biting horseflies: battle between ammonia, CO₂, and colour pattern for dominance in the sensory systems of host-seeking tabanids.

    abstract::As with mosquitoes, female tabanid flies search for mammalian hosts by visual and olfactory cues, because they require a blood meal before being able to produce and lay eggs. Polarotactic tabanid flies find striped or spotted patterns with intensity and/or polarisation modulation visually less attractive than homogene...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/j.physbeh.2013.06.013

    authors: Blahó M,Egri A,Száz D,Kriska G,Akesson S,Horváth G

    更新日期:2013-07-02 00:00:00

  • An activity indicator of acute withdrawal depends on amphetamine dose in rats.

    abstract::A moderate dose of amphetamine (AMPH) produces hypoactivity around 20 h post-administration. This hypoactivity may be an indicator of an acute withdrawal state. The purpose was to see how AMPH doses affected the expression of this hypoactivity and, by inference, AMPH-induced acute withdrawal. Rats were housed in indiv...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/j.physbeh.2005.10.009

    authors: White W,White IM

    更新日期:2006-02-28 00:00:00

  • Circumventricular organs: targets for integration of circulating fluid and energy balance signals?

    abstract::The subfornical organ (SFO), as one of the sensory circumventricular organs (CVOs), is among the only central nervous system structures which interfaces directly with circulating substances that do not cross the blood brain barrier. Here we describe a growing literature showing that circulating indicators of cardiovas...

    journal_title:Physiology & behavior

    pub_type: 杂志文章,评审

    doi:10.1016/j.physbeh.2013.02.012

    authors: Mimee A,Smith PM,Ferguson AV

    更新日期:2013-09-10 00:00:00