Abstract:
PURPOSE:To describe a case of infantile neuroaxonal dystrophy with optic nerve atrophy and to discuss the diagnostic role of conjunctival biopsy. METHODS:We performed a complete ophthalmologic examination and a diagnostic conjunctival biopsy on a girl with a neurodegenerative disease. RESULTS:On the basis of "spheroid" inclusions in the unmyelinated axons, we diagnosed infantile neuoroaxonal dystrophy. CONCLUSIONS:Optic atrophy is an important finding in infantile neuroaxonal dystrophy, and conjunctival biopsy is a reliable and very convenient diagnostic test.
journal_name
Am J Ophthalmoljournal_title
American journal of ophthalmologyauthors
Ferreira RC,Mierau GW,Bateman JBdoi
10.1016/s0002-9394(14)71051-7subject
Has Abstractpub_date
1997-02-01 00:00:00pages
264-6issue
2eissn
0002-9394issn
1879-1891pii
S0002-9394(14)71051-7journal_volume
123pub_type
杂志文章abstract::We reviewed the records of 74 patients with exfoliation syndrome. Patients with exfoliation syndrome represented 12% of the current Glaucoma Clinic population. There were 40 unilateral and 34 bilateral cases. Thirteen percent of the patients who originally had unilateral exfoliation later developed exfoliation in the ...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/0002-9394(80)90054-9
更新日期:1980-04-01 00:00:00
abstract:PURPOSE:To compare tear protein markers between normal subjects and patients with dry eye (DE) and high and low lymphotoxin-alpha (LT-α) levels. DESIGN:Prospective cross-sectional study. METHODS:Patients with DE were divided into low (≤700 pg/mL) and high (>700 pg/mL) LT-α groups. Twelve protein markers were measured...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2020.03.013
更新日期:2020-09-01 00:00:00
abstract:PURPOSE:We report a case of a submacular surgery complicated by a choroidal neovascular membrane at the retinotomy site. METHOD:The patient underwent submacular surgery for the removal of an idiopathic choroidal neovascular membrane. RESULT:Three weeks after surgery, the patient developed a choroidal neovascular memb...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(14)70499-4
更新日期:1996-11-01 00:00:00
abstract:PURPOSE:We investigated whether opsin mislocalization occurs in photoreceptors in a female carrier of X-linked retinitis pigmentosa with a Gly436Asp mutation in the retinitis pigmentosa GTPase regulator gene (RPGR). DESIGN:Histologic findings in autopsy eyes from a carrier were compared with those from a normal female...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2006.03.061
更新日期:2006-09-01 00:00:00
abstract:PURPOSE:To determine the type of herpes simplex virus in acute retinal necrosis syndrome associated with herpes simplex virus. METHODS:Herpes simplex virus type 1, herpes simplex virus type 2, varicella-zoster virus, Epstein-Barr virus, and cytomegalovirus were examined by polymerase chain reaction in intraocular spec...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(99)00391-8
更新日期:2000-03-01 00:00:00
abstract:PURPOSE:To investigate the relationship of circulating levels of soluble form of LR11 (sLR11; also called SorLA or SORL1), with the progression of proliferative diabetic retinopathy (PDR) in patients with type 2 diabetes mellitus. DESIGN:Cross-sectional study. METHODS:Fifty-four patients with type 2 diabetes mellitus...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2012.01.035
更新日期:2012-07-01 00:00:00
abstract:PURPOSE:To determine whether a machine learning technique called Kalman filtering (KF) can accurately forecast future values of mean deviation (MD), pattern standard deviation, and intraocular pressure for patients with normal tension glaucoma (NTG). DESIGN:Development and testing of a forecasting model for glaucoma p...
journal_title:American journal of ophthalmology
pub_type: 杂志文章,多中心研究
doi:10.1016/j.ajo.2018.10.012
更新日期:2019-03-01 00:00:00
abstract::We managed three cases of congenital iris stromal cysts and compared them with 22 cases in the published reports to delineate the clinical features of this condition and determine the best treatment. Our first patient, a 5-month-old girl, had injection of a cyst with trichloroacetic acid, but developed a cataract and ...
journal_title:American journal of ophthalmology
pub_type: 杂志文章,评审
doi:10.1016/s0002-9394(14)71291-7
更新日期:1993-08-15 00:00:00
abstract:PURPOSE:To investigate the effect of yellow-tinted intraocular lenses (IOLs) on short-wavelength automated perimetry (SWAP). DESIGN:Cross-sectional observation study. METHODS:Twenty-two patients who had implantation of yellow-tinted IOLs (AcrySof SN60AT or SN60WF; Alcon Laboratories) in 1 eye and nontinted IOLs (Acry...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2010.02.023
更新日期:2010-08-01 00:00:00
abstract:PURPOSE:To study the appearance of margins of geographic atrophy in high-resolution optical coherence tomography (OCT) images and to correlate those changes with fundus autofluorescence (FAF) imaging. DESIGN:Retrospective, observational case study. METHODS:Patients with geographic atrophy secondary to dry age-related...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2009.04.022
更新日期:2009-09-01 00:00:00
abstract::A 29-year-old white man developed a corneal ulcer following trauma to his left cornea by a piece of wire. Tritirachium roseum, a saprophytic fungus, was cultured from corneal scrapings and demonstrated in the corneal button by histopathologic examination. ...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/0002-9394(75)90275-5
更新日期:1975-11-01 00:00:00
abstract:PURPOSE:To measure lead and cadmium in retinal tissues of human donor eyes with and without age-related macular degeneration (AMD). DESIGN:Laboratory investigation. METHODS:Lead and cadmium concentrations in retinal tissues (neural retina and retinal pigment epithelium [RPE]-choroid complex) in 25 subjects with AMD (...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2009.07.001
更新日期:2009-12-01 00:00:00
abstract:PURPOSE:To investigate the prevalence and associations of visual impairment and spectacle use in university students in central China. DESIGN:Cross-sectional study. METHODS:This study included students aged 16-26 years in China. Study subjects from 2 universities underwent distance visual acuity (VA) assessment in bo...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2019.04.026
更新日期:2019-10-01 00:00:00
abstract:PURPOSE:To describe clinical outcomes of complications afflicting the autologous oral mucous membrane graft after modified osteo-odonto keratoprosthesis surgery in chronic Stevens-Johnson syndrome (SJS). DESIGN:Prospective case series. METHODS:This study included 30 eyes of 30 patients with SJS-induced dry keratinize...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2013.06.012
更新日期:2013-11-01 00:00:00
abstract:PURPOSE:To investigate the prevalence of and risk factors associated with dry eye syndrome (DES) in South Korea. DESIGN:Cross-sectional study. METHODS:In 2010 and 2011, 11,666 subjects, ranging in age from 19 to 95, were randomly selected as nationally representative participants in the Korea National Health and Nutr...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2014.08.021
更新日期:2014-12-01 00:00:00
abstract:PURPOSE:To report the use of an Apligraf (Organogenesis, Inc., Canton, Massachusetts, USA) human skin equivalent for repair of cicatricial ectropion in a patient with harlequin ichthyosis. DESIGN:Interventional case report. METHODS:A 6-week-old male child with harlequin ichthyosis and severe bilateral upper eyelid ci...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(02)01567-2
更新日期:2002-09-01 00:00:00
abstract:PURPOSE:To compare the intraocular pressure)-lowering effect and side effects of latanoprost 0.005% once daily with unoprostone 0.12% twice daily. METHODS:Sixty patients with primary open-angle glaucoma or ocular hypertension were randomized to receive either latanoprost once daily in the evening and placebo once dail...
journal_title:American journal of ophthalmology
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:10.1016/s0002-9394(00)00943-0
更新日期:2001-05-01 00:00:00
abstract::We treated seven patients (all male, ranging in age from 11 to 31 years) with Schwartz syndrome, a combination of uveitis, high intraocular pressure, and retinal detachment with peripheral tears. The condition was resistant to corticosteroids but responded well to surgery. Puncture of the anterior chamber disclosed ma...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/0002-9394(86)90767-1
更新日期:1986-06-15 00:00:00
abstract::A 13-year-old boy developed an osteogenic sarcoma of the right humerus ten years after treatment for bilateral retinoblastoma. The bilateral retinoblastoma has been managed with enucleation of one eye and successful treatment of the solitary tumor in the other eye with a single application of a local 10-mm round cobal...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(14)74919-0
更新日期:1980-09-01 00:00:00
abstract::We investigated the influence of a racial match or mismatch between the corneal donor and recipient on the risk of endothelial rejection and subsequent graft failure in 998 corneal transplant recipients. Actuarial survival analysis showed no significant difference in the cumulative risk of endothelial rejection betwee...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/0002-9394(88)90058-x
更新日期:1988-06-15 00:00:00
abstract:PURPOSE:To characterize outcomes for patients who develop full-thickness macular holes after pars plana vitrectomy. METHODS:We retrospectively analyzed data for 47 consecutive patients (47 eyes) who developed full-thickness macular holes after initial pars plana vitrectomy for a variety of indications. All patients un...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2008.01.030
更新日期:2008-06-01 00:00:00
abstract::Corneas for penetrating keratoplasty that have been excised from the globe for storage ordinarily require punching of the donor tissue from the posterior surface. They may be trephined from the anterior surface when they are mounted on an instrument that forms a seal around the scleral rim of the excised cornea, allow...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/0002-9394(76)90021-0
更新日期:1976-11-01 00:00:00
abstract:PURPOSE:To evaluate the long-term risk of endothelial rejection, graft survival, and associated factors following penetrating keratoplasty (PK) for keratoconus, with and without prior resolved corneal hydrops. DESIGN:Retrospective cohort study. METHODS:Primary outcome measures were endothelial rejection-free survival...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2016.07.001
更新日期:2016-09-01 00:00:00
abstract:PURPOSE:To determine the frequency of ocular adverse effects associated with vemurafenib (PLX4032) treatment for metastatic cutaneous melanoma. DESIGN:Retrospective review of the clinical study reports from the clinical pharmacology, phase 1, phase 2, and phase 3 trials of vemurafenib. METHODS:The vemurafenib clinica...
journal_title:American journal of ophthalmology
pub_type: 杂志文章,多中心研究
doi:10.1016/j.ajo.2014.07.003
更新日期:2014-10-01 00:00:00
abstract:PURPOSE:To perform a cross-sectional study on the distribution of central corneal thickness and its association with intraocular pressure in an elderly population. METHODS:We measured central corneal thickness and intraocular pressure in 395 subjects (352 control subjects, 13 patients with ocular hypertension, and 30 ...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(14)71125-0
更新日期:1997-06-01 00:00:00
abstract::We compared the intraocular pressure in 150 urban household contacts of patients with Hansen's disease and 132 endemic control subjects from an urban population in Karachi, Pakistan, who were matched in regard to race, age, gender, and socioeconomic status. The mean intraocular pressure in the upright position was 12....
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(14)71861-6
更新日期:1992-10-15 00:00:00
abstract:PURPOSE:To report the use of intravitreal injection of triamcinolone acetonide during the acute phase of Vogt-Koyanagi-Harada disease. DESIGN:Prospective interventional case series. METHODS:Three eyes from two patients at the acute phase of Vogt-Koyanagi-Harada disease with serous retinal detachments were treated wit...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2003.08.035
更新日期:2004-03-01 00:00:00
abstract::We conducted a prospective randomized clinical trial on the use of 2% hydroxypropyl methylcellulose and 1% sodium hyaluronate in the anterior chamber during anterior capsulotomy and nuclear expression in extracapsular cataract extraction with posterior chamber lens implantation in 70 patients. Both viscoelastic substa...
journal_title:American journal of ophthalmology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/0002-9394(86)90399-5
更新日期:1986-12-15 00:00:00
abstract:PURPOSE:To evaluate the relationship between visual function and retinal nerve fiber layer (RNFL) measurements obtained with scanning laser polarimetry with variable corneal compensation (SLP-VCC) and optical coherence tomography (OCT). DESIGN:Cross-sectional analysis of normal and glaucomatous eyes in a tertiary care...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(02)02077-9
更新日期:2003-04-01 00:00:00
abstract::We used a technique for surgical management of fibrovascular membranes to relieve epiretinal tangential traction when present in proliferative diabetic retinopathy. Sharp dissection with intraocular scissors was used to segment fibrovascular and cortical vitreous membranes together with cauterization of large vessels ...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/0002-9394(80)90012-4
更新日期:1980-03-01 00:00:00