Abstract:
:With the decline of the former main causes of death in early childhood--infections and starvation--sudden infant death syndrome (SIDS) has emerged as the most important single cause of postneonatal infant mortality. It has adopted the role of a major indicator for the standard of public health care. Despite extensive input into research, its pathophysiology has remained rather obscure. The resulting helplessness of scientists and health care professionals have lead to adherence to unconfirmed pathophysiological hypotheses and to pursuit of preventive strategies of doubtful efficacy. In this overview, the medical and technical background of five major hypotheses is being presented. A lot can be learnt from the history of their development, efforts to refute them, and the reasons for unreflected adherence to them. (1) Due to its illustrative nature, the so-called 'status thymico-lymphaticus', the theory of asphixation by an enlarged thymus, could not be eradicated although well-reknowned physicians--including the Austrian pathologist Paltauf--have repeatedly attempted to do so. (2) Assumed familiarity, an aspect which attracted the attention of pediatricians to SIDS initially has been excluded, but an increased risk of SIDS for the siblings of affected babies is still common belief. (3) The sleep-apnea-hypothesis has turned out a complete error with serious consequences, but home apnea monitors are still being widely recommended. (4) The rise of SIDS in the 80ies and its subsequent decline in the 90ies has been interpreted as the advent and successful control of an epidemic although significant numbers of cot death have been reported long before the turn of the century, and the apparent increase which paralleled the introduction of the 9th edition of the ICD code is most likely due to improved registration. (5) Finally, SIDS is still being considered a random event--ignoring all evidence of an obvious role of socioeconomical factors.
journal_name
Wien Klin Wochenschrjournal_title
Wiener klinische Wochenschriftauthors
Paky F,Kytir Jsubject
Has Abstractpub_date
2000-03-10 00:00:00pages
193-7issue
5eissn
0043-5325issn
1613-7671journal_volume
112pub_type
杂志文章,评审abstract::A statistic evaluation of the daily blood pressure values at rest during a 4-week period of active training combined with physiotherapy and medical baths indicated a decrease of 20 mm Bg in systolic pressure and of 9 mm Hg in diastolic pressure in patients with hypertension of various grades. The resting blood pressur...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:
更新日期:1976-03-19 00:00:00
abstract::Two major features of atherosclerosis may be distinguished: (a) atherosis caused by lipid infiltration in cells and extracellularly and (b) sclerosis caused by connective tissue deposition and by functional disturbance of the endothelium, leading to impairment of endothelium-derived relaxing factor (EDRF)-release and ...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章,评审
doi:
更新日期:1992-01-01 00:00:00
abstract::Concomitant hydrocortisone and arginine vasopressin therapy increases arginine vasopressin plasma levels and may improve survival in septic shock. The objective of this post hoc analysis of a prospective study was to determine whether hydrocortisone therapy increases arginine vasopressin plasma levels in patients with...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:10.1007/s00508-011-1568-5
更新日期:2011-04-01 00:00:00
abstract:BACKGROUND:Endoscopic sphincterotomy has a higher risk of bleeding in patients with cirrhosis. Advanced Child stage and coagulopathy are well-known risk factors. We aimed to determine the role of electrosurgical currents in the development of endoscopic sphincterotomy bleeding in cirrhotic patients. METHODS:The study ...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:10.1007/s00508-014-0677-3
更新日期:2016-08-01 00:00:00
abstract::The importance of hypercholesterolemia for the development of atherosclerotic lesions is undebatable. It is less evident, however, whether the progression of established lesions can be influenced by modifying lipid levels. The review of seven controlled angiographic intervention trials shows that different criteria ar...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章,评审
doi:
更新日期:1992-01-01 00:00:00
abstract::Urological conditions of infancy and childhood account for the largest single disease group requiring either surgical or medical intervention. This makes early detection and classification of abnormalities mandatory. This study presents an analysis of the results of ultrasonic screening in 1000 patients. Ultrasonic ex...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:
更新日期:1985-01-04 00:00:00
abstract::In nine patients with meconium peritonitis prenatal ultrasonographic findings were correlated with the clinical course and outcome. Ultrasound findings included polyhydramnion (n = 4), ascites (n = 4), disseminated (n = 3) and solitary echogenic areas (n = 1), echopoor cystic areas (n = 3) and echogenic-echopoor solit...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:
更新日期:1995-01-01 00:00:00
abstract::Morphological examination of the fundus has improved considerably over the past decade. By means of identation biomicroscopy, hitherto inaccessible, extremely-peripheral areas of the fundus can be examined by the slit lamp now; this of importance in the study of intraocular inflammation and the judgement of retinal te...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:
更新日期:1978-06-23 00:00:00
abstract:INTRODUCTION:The purpose of this retrospective population based study was to investigate the effect of the extent of surgery on overall survival in young versus adult glioblastoma patients in Vorarlberg/Austria during the last 4 years. METHODS:Forty-eight patients (median age 62.5 years, ranging from 25-82 years, 19 f...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:10.1007/s00508-011-1577-4
更新日期:2011-06-01 00:00:00
abstract::Although glucocorticoids have been universally implemented to stimulate fetal lung maturity, their effectiveness and side effects are still widely contested. In search of alternative drugs a double-blind study was conducted between June 1981 and June 1984 comparing betamethasone, a conventional corticoid, and ambroxol...
journal_title:Wiener klinische Wochenschrift
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1990-08-03 00:00:00
abstract::A case of the first ocular thelaziosis in a human male patient in Croatia is presented. Thelaziosis is a zoonosis caused by the nematodes of the genus Thelazia. In all, two types of the genus have been described as causes of infection in humans, Thelazia callipaeda and Thelazia californiensis. This zoonosis, called "o...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:10.1007/s00508-015-0889-1
更新日期:2016-03-01 00:00:00
abstract:INTRODUCTION:Air insufflation during colonoscopy is considered the standard method in most endoscopic centers. Notably, several studies have reported reduced abdominal pain after colonoscopy with CO2 insufflation in unsedated and in lightly sedated patients. The present study was designed to assess the efficacy of CO2 ...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00508-009-1202-y
更新日期:2009-01-01 00:00:00
abstract::The efficacy of gentamicin given intravenously once daily in a single, individually-adapted dose in form of a short infusion was confirmed in 30 patients with febrile urogenitary infections, taking nephrotoxicity into consideration. Antibiotic therapy was given for 7 days in each case, the individual dose of gentamici...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:
更新日期:1990-05-25 00:00:00
abstract:OBJECTIVE AND METHODS:The aim of the study was to investigate the prevalence of excessive computer game playing behaviour among adolescents with psychopathological tendencies that resemble the classic symptoms of addiction. To address this question, criteria for excessive computer game playing behaviour were developed ...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:10.1007/s00508-009-1198-3
更新日期:2009-01-01 00:00:00
abstract:INTRODUCTION:The assessment of HER2/neu overexpression in tissue provides information about one of the most relevant prognostic and predictive markers in breast cancer: overexpression of HER2/neu is associated with worse prognosis in primary breast cancer. Since core needle biopsy is increasingly used for the diagnosis...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:10.1007/BF03040420
更新日期:2004-01-31 00:00:00
abstract::Sentinel node biopsy (SNB) has proved to be a useful and accurate procedure for lymph node staging in breast cancer and melanoma and should be standard of care in the treatment of these tumors. In other malignancies (colon, rectum, stomach, esophagus, head and neck and thyroid, cervix uteri) it is still under investig...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章,评审
doi:10.1007/s00508-005-0320-4
更新日期:2005-02-01 00:00:00
abstract::Serial determinations of serum HPL and HCG levels were carried out in 68 diabetic women during the whole course of pregnancy. In diabetic pregnancies of the type B--D according to White's classification, HPL levels were significantly lower than control values from the 10th to the 22nd week. In diabetic pregnancies of ...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:
更新日期:1977-08-12 00:00:00
abstract:BACKGROUND:Despite evidence for a bidirectional relationship between obesity and stress-related mental disorders, the general relationship between psychological stress and metabolism is still controversial. Only few studies have addressed this relationship in morbidly obese individuals. METHODS:The present study inves...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:10.1007/s00508-019-01583-y
更新日期:2020-03-01 00:00:00
abstract::Body temperature follows a circadian rhythm with a low around 6 a.m. and a peak about 12 hours later. The effect of fever on this endogenous oscillation is unknown. We obtained hourly measurements of the rectal temperature of 66 children with Plasmodium falciparum malaria. Even at febrile temperatures, the temperature...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:
更新日期:2000-12-07 00:00:00
abstract::The first successful smallpox vaccination with cowpox lymph outside of England was carried out in Vienna--only ten months after the publication of Edward Jenner's book "An Inquiry into the Causes and Effects of the Variolae Vaccinae, a Disease ... known by the Name of the Cow Pox", and only a little more than three mo...
journal_title:Wiener klinische Wochenschrift
pub_type: 历史文章,杂志文章
doi:
更新日期:1999-04-23 00:00:00
abstract::We compared obstetric data from the archives in Graz for 1887 with those of 1987. In 1887, 85% of all deliveries took place in the home or with a midwife--compared with only 0.46% in 1987. Maternal mortality in 1887 was 0.75%; two-thirds of the deaths occurred in the puerperium. Perinatal mortality was 11.0% in 1887 a...
journal_title:Wiener klinische Wochenschrift
pub_type: 历史文章,杂志文章
doi:
更新日期:1989-12-22 00:00:00
abstract::The case is reported of a 26 year-old man with a colloid cyst of the third ventricle (paraphyseal cyst; neuroepithelial cyst), which gave rise to a fatal increase in intracranial pressure. Despite repeated hospitalisation the diagnosis was not established prior to death. This report serves as a reminder that this rare...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:
更新日期:1987-03-20 00:00:00
abstract::Serum levels of LH, FSH, HPRL, oestradiol, progesterone and testosterone were determined by radioimmunoassay in 45 postmenopausal patients in the morning before they were operated on for primary breast cancer. Cytosol oestradiol - (E2R) and progesterone receptor (PgR) levels were estimated by Scatchard plot analysis o...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:
更新日期:1981-05-29 00:00:00
abstract::Intussusception is a rare clinical finding in adults. Most cases occur in the distal small bowel or large intestine. We report the case of a 65-year-old woman with known non-small-cell lung cancer (NSCLC) who presented with acute abdomen and ileus-like symptoms. Abdominal computed tomography suggested ileocecal intuss...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:10.1007/s00508-009-1146-2
更新日期:2009-01-01 00:00:00
abstract::Satellite associations and cell-cycle kinetics were investigated in short-term blood cultures from selected pairs of chromosomally normal persons and patients with trisomy 21. The cell-cycle duration was found to be longer in patients with trisomy than in normal persons. The frequency of satellite associations and the...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:
更新日期:1981-01-09 00:00:00
abstract::Forensic complications involving criminal or civil law are generally rare in depressive disorders, but are of varied nature and of great consequence to the person concerned. Suicide, which is the problem of greatest practical importance may have far-reaching consequences with regard to legal insurance, apart from the ...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:
更新日期:1985-02-15 00:00:00
abstract::It is well recognized that organized management of heart failure patients, including care by heart failure specialists, improves outcomes of these patients. In response to this, the Heart Failure Association of the European Society of Cardiology proposed a basic framework of a heart failure curriculum, which became a ...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:10.1007/s00508-019-1480-y
更新日期:2019-07-01 00:00:00
abstract::In a 29 year-old female occlusions of both femoral arteries were caused by the administration of ergotamine in the form of Cafergot-suppositories. Angiographically long smooth-walled stenoses and occlusions over a segment of approximately 5 cm length in each superficial femoral artery as well as occlusions of both tib...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:
更新日期:1978-03-03 00:00:00
abstract::Leiomyomatosis peritonealis disseminata is a rare disease. Approximately 50 cases have been reported in the world literature so far. Origination from the Müllerian epithelium, which is distributed throughout the subperitoneal mesenchyme seems possible in histogenesis. By specific hormonal stimulation and individual pr...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:
更新日期:1996-01-01 00:00:00
abstract::Transmission of Cryptosporidium sp. within the general public was studied. We were looking for a possible risk of infection associated with animal contacts. Investigation of the animal contacts of affected individuals led to the formulation of the hypothesis that animals are a source of cryptosporidiosis. The research...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:10.1007/BF03040292
更新日期:2003-02-28 00:00:00