Abstract:
BACKGROUND:Changes in plasma lipid and lipoprotein distributions that occur after menopause increase the risk of cardiovascular disease in women, especially in those who are overweight. OBJECTIVE:The purpose of this study was to evaluate the impact of a nine-month weight reduction program on plasma lipids, dietary intake and abdominal fat obesity. DESIGN:A partial crossover design was used to study a weight loss treatment consisting of Phentermine hydrochloride (Fastin, SmithKline Beecham Pharmaceuticals, Philadelphia, PA) therapy plus a low energy diet (5040 kJ/d). Forty-seven obese, postmenopausal Caucasian women (BMI of 30-38 kg/m2) were randomized into two groups, both of which received drug and diet treatment over six months. However, Group I started the intervention program three months later than Group II. Plasma total, HDL and LDL cholesterol and triacylglycerol were measured, body composition was assessed by anthropometry and dual energy x-ray absorptiometry, and food frequency records were collected at four timepoints. RESULTS:Over nine months, women in Group II reduced body weight (14.4%), lowered plasma concentrations of LDL cholesterol (14% to 26%) and triacylglycerol (15%) and raised plasma HDL cholesterol concentration (15%). These plasma lipid changes decreased the total cholesterol/HDL cholesterol ratio from 4.3 to 3.2. All subjects decreased abdominal fat measurements and energy and cholesterol intakes, as well as percentage of energy derived from total and saturated fat during the study. Most subjects also increased dietary fiber consumption. CONCLUSION:Both weight loss and diet modifications are associated with an improved plasma lipid profile in obese postmenopausal women.
journal_name
J Am Coll Nutrjournal_title
Journal of the American College of Nutritionauthors
Cordero-MacIntyre ZR,Lohman TG,Rosen J,Peters W,España RC,Dickinson B,Reid PM,Howell WH,Fernandez MLdoi
10.1080/07315724.2000.10718927subject
Has Abstractpub_date
2000-04-01 00:00:00pages
275-84issue
2eissn
0731-5724issn
1541-1087journal_volume
19pub_type
临床试验,杂志文章,随机对照试验abstract:BACKGROUND:Premature infants require high intakes of Ca and P to mimic fetal accretion rates. With the current phosphate salt used, adequate amounts cannot be provided due to the precipitation of Ca and P in TPN solutions. OBJECTIVE:To compare monobasic potassium phosphate (monobasic regimen) and monobasic plus dibasi...
journal_title:Journal of the American College of Nutrition
pub_type: 杂志文章
doi:10.1080/07315724.2006.10719517
更新日期:2006-02-01 00:00:00
abstract:OBJECTIVE:To identify if particular foods or food groups may be associated with obesity in children and adolescents and to determine if consuming food away from home (FAFH) has an effect on the nutritional quality of their diets. DESIGN:One-year cross-sectional study. SETTING/SUBJECTS:The obese subjects (n = 91) were...
journal_title:Journal of the American College of Nutrition
pub_type: 杂志文章
doi:10.1080/07315724.2003.10719333
更新日期:2003-12-01 00:00:00
abstract::Agricultural biotechnology has been widely adopted in agriculture but is also the focus of controversy. Questions have arisen regarding food and environmental safety. In the US, responsibility for ensuring agricultural and environmental safety is delegated to the USDA and EPA, respectively. The FDA has primary respons...
journal_title:Journal of the American College of Nutrition
pub_type: 杂志文章,评审
doi:10.1080/07315724.2002.10719261
更新日期:2002-06-01 00:00:00
abstract:OBJECTIVE:To examine the efficacy of l-alanyl-l-glutamine ingestion with a commercially available sports drink compared to the sports drink only on time to exhaustion and physiological measures during prolonged endurance exercise. METHODS:Twelve endurance-trained men (23.5 ± 3.7 years; 175.5 ± 5.4 cm; 70.7 ± 7.6 kg) p...
journal_title:Journal of the American College of Nutrition
pub_type: 杂志文章
doi:10.1080/07315724.2015.1009193
更新日期:2015-01-01 00:00:00
abstract:OBJECTIVE:The following review of the literature on the importance of Selenium (Se) in myocardial homeostasis and of the pharmacology of this trace metal, represents an attempt to search, without prejudice to other possible explanations, for a rationale of a beneficial effect of Se substitution as an adjuvant to antiar...
journal_title:Journal of the American College of Nutrition
pub_type: 杂志文章,评审
doi:10.1080/07315724.1994.10718441
更新日期:1994-10-01 00:00:00
abstract:OBJECTIVE:This study was designed to determine the composition of postprandial triglyceride-rich lipoproteins (TRL) after the intake of pomace olive oil (POO), which is a subproduct of the extraction of virgin olive oil (VOO) and presents a high concentration of minor components with biological activity. METHODS:Meals...
journal_title:Journal of the American College of Nutrition
pub_type: 杂志文章,随机对照试验
doi:10.1080/07315724.2007.10719582
更新日期:2007-02-01 00:00:00
abstract:OBJECTIVE:To compare oxidative stress and LDL oxidizability in postmenopausal women with and without HRT. METHODS:In a cross sectional study, two groups of women, with or without combined per os HRT (1.5-2 mg estrogen associated with 10 mg dydrogesteron), were age and duration of menopause matched. Women were recruite...
journal_title:Journal of the American College of Nutrition
pub_type: 杂志文章
doi:10.1080/07315724.2002.10719231
更新日期:2002-08-01 00:00:00
abstract:BACKGROUND:Boron is an essential micronutrient for higher plants. The results of studies in animals and humans have suggested a potential role for boron as a modulator of the steroid hormone pathway. METHODS:As part of a study to obtain baseline information on boron in humans, the boron content of selected foods (66 i...
journal_title:Journal of the American College of Nutrition
pub_type: 杂志文章
doi:10.1080/07315724.1996.10718638
更新日期:1996-12-01 00:00:00
abstract::The potential relationship between red meat consumption and colorectal cancer (CRC) has been the subject of scientific debate. Given the high degree of resulting uncertainty, our objective was to update the state of the science by conducting a systematic quantitative assessment of the epidemiologic literature. Specifi...
journal_title:Journal of the American College of Nutrition
pub_type: 杂志文章,meta分析,评审
doi:10.1080/07315724.2014.992553
更新日期:2015-01-01 00:00:00
abstract::Respiratory function in mechanically ventilated patients (VP) is adversely affected by starvation and hypermetabolic stress. These patients are more successfully managed and extubated if proper nutritional support is provided. The features of metabolism and respiratory function in VP require moderation in glucose, fat...
journal_title:Journal of the American College of Nutrition
pub_type: 杂志文章
doi:10.1080/07315724.1983.10719906
更新日期:1983-01-01 00:00:00
abstract::Since trivalent chromium (Cr+3) transport into certain tissues is rapid, the placental transport of injected high specific activity 51Cr+3 was studied in pregnant rats at days 17-20 of gestation. Three days after the intravenous injection of 51Cr+3, body retention of 51Cr was similar in pregnant and nonpregnant rats, ...
journal_title:Journal of the American College of Nutrition
pub_type: 杂志文章
doi:10.1080/07315724.1984.10720038
更新日期:1984-01-01 00:00:00
abstract:OBJECTIVE:Baseline characteristics of subjects might be related to the effect of plant stanols on the serum lipoprotein profile. The aim of the study was to examine effects of subjects' baseline characteristics (baseline serum concentrations of lipids and lipoproteins at the start of the study, lathosterol, campesterol...
journal_title:Journal of the American College of Nutrition
pub_type: 杂志文章
doi:10.1080/07315724.2008.10719683
更新日期:2008-02-01 00:00:00
abstract:OBJECTIVE:To investigate the effect of diet alone (D), exercise alone (E), and a combination of diet and exercise (DE) on body weight, body composition, energy intake, blood pressure, serum lipid and leptin levels, and fitness levels in mildly obese sedentary women and men. DESIGN:The three interventions were compared...
journal_title:Journal of the American College of Nutrition
pub_type: 杂志文章,随机对照试验
doi:10.1080/07315724.2008.10719691
更新日期:2008-04-01 00:00:00
abstract:OBJECTIVE:The goal of this work is to assess the effect of L-carnitine on glucose disposal, particularly on insulin sensitivity, in healthy volunteers. METHODS:Fourteen healthy human volunteers were subjected to the intravenous glucose tolerance test (analyzed by means of the minimal model technique), together with in...
journal_title:Journal of the American College of Nutrition
pub_type: 杂志文章
doi:10.1080/07315724.1999.10718866
更新日期:1999-08-01 00:00:00
abstract:OBJECTIVE:To investigate whether a drink enriched with essential vitamins and minerals can improve biochemical status of enzymatic and non-enzymatic antioxidants in frail elderly people. METHODS:A six-month randomized, double blind, placebo controlled intervention study. Frail elderly people 65 years of age or older, ...
journal_title:Journal of the American College of Nutrition
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1080/07315724.2003.10719298
更新日期:2003-06-01 00:00:00
abstract:OBJECTIVES:In view of the prevalence of osteoporosis in Japan, which surveys have shown has almost doubled over the last ten years, contributory factors, additional to the mineral status, that affect bone stiffness have been explored in spontaneously obese (Minko) rats. METHODS:Bone stiffness and strength as well as c...
journal_title:Journal of the American College of Nutrition
pub_type: 杂志文章
doi:10.1080/07315724.2004.10719414
更新日期:2004-12-01 00:00:00
abstract:OBJECTIVE:We tested whether an extreme running competition ("Marathon of Sands") might alter the blood's enzymatic and non-enzymatic antioxidant status in 6 well-trained athletes. METHODS:The Marathon of Sands is a competition consisting of six long duration races in the desert in which the athletes carry their own fo...
journal_title:Journal of the American College of Nutrition
pub_type: 杂志文章
doi:10.1080/07315724.2004.10719379
更新日期:2004-08-01 00:00:00
abstract::Objective: We assessed the acute effect of beetroot extract intake on cardiovascular and autonomic recovery subsequent to strength exercise.Methods: This is a crossover, randomized, double-blind and placebo-controlled trial. We assessed 16 subjects but only 12 healthy male adults completed the two protocols in two ran...
journal_title:Journal of the American College of Nutrition
pub_type: 杂志文章
doi:10.1080/07315724.2020.1774441
更新日期:2020-05-29 00:00:00
abstract:OBJECTIVE:Adequate dietary potassium intake is associated with a reduced risk of cardiovascular and other chronic diseases. The Dietary Guidelines for Americans 2005 identifies milk and milk products as a major contributor of dietary potassium and lists dairy products, along with fruits and vegetables, as food groups t...
journal_title:Journal of the American College of Nutrition
pub_type: 杂志文章
doi:10.1080/07315724.2008.10719673
更新日期:2008-02-01 00:00:00
abstract::There is an increased requirement for nutrients in normal pregnancy, not only due to increased demand, but also increased loss. There is also an increased insulin-resistant state during pregnancy mediated by the placental anti-insulin hormones estrogen, progesterone, human somatomammotropin; the pituitary hormone prol...
journal_title:Journal of the American College of Nutrition
pub_type: 杂志文章,评审
doi:10.1080/07315724.1996.10718560
更新日期:1996-02-01 00:00:00
abstract::The purported health benefits of low-carbohydrate diets have been advocated intermittently over the last century and have enjoyed increasing popularity over the last decade. Although most revolve around the emphatic theme that carbohydrates are to blame for many chronic diseases, their specific ideologies are more var...
journal_title:Journal of the American College of Nutrition
pub_type: 杂志文章,评审
doi:10.1080/07315724.2003.10719271
更新日期:2003-02-01 00:00:00
abstract::To study the role of diet as a risk factor for coronary heart disease (CHD), 463 adults (25-65 years, 419 males) at risk of or with CHD were assigned to group A (n = 231) receiving a cardiovasoprotective diet or group B (n = 232) receiving a normal diet in a randomized, single-blind fashion. Age, sex, risk factors and...
journal_title:Journal of the American College of Nutrition
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1080/07315724.1992.10718242
更新日期:1992-08-01 00:00:00
abstract:OBJECTIVE:Nutritional status-related biological indexes were measured in fit, health-conscious elderly subjects in order to establish reference values for people over 70 years. SUBJECTS:103 men and 90 women aged 70-89 years living freely in the Paris area volunteered to participate. METHODS:Nutritional status was ass...
journal_title:Journal of the American College of Nutrition
pub_type: 杂志文章
doi:10.1080/07315724.1994.10718461
更新日期:1994-12-01 00:00:00
abstract:OBJECTIVE:Magnesium deficiency and oxidative stress have both been identified as pathogenic factors in aging and in several age-related diseases. The link between these two factors is unclear in humans although, in experimental animals, severe Mg deficiency has been shown to lead to increased oxidative stress. METHODS...
journal_title:Journal of the American College of Nutrition
pub_type: 杂志文章
doi:10.1080/07315724.2000.10718934
更新日期:2000-06-01 00:00:00
abstract::Exogenous, microbial beta-D-galactosidases are capable of effecting hydrolysis of lactose in situ in the gastrointestinal tract of lactase-deficient subjects when given as replacement therapy at mealtime. As its digestion products-glucose and galactose-are known to inhibit lactose hydrolysis in vitro, the effect of ad...
journal_title:Journal of the American College of Nutrition
pub_type: 杂志文章
doi:10.1080/07315724.1986.10720131
更新日期:1986-01-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Micronutrients may influence the development and differentiation of sperm cells. The aim of this study was to assess the possible association of deficiencies in several vitamins and trace elements with sperm abnormalities in men with obesity. PARTICIPANTS AND METHODS:Thirty male patients with...
journal_title:Journal of the American College of Nutrition
pub_type: 杂志文章
doi:10.1080/07315724.2017.1387877
更新日期:2018-03-01 00:00:00
abstract:OBJECTIVE:Food frequency questionnaires (FFQs) estimate habitual dietary intake and require evaluation in populations of interest in order to determine accuracy. Thus, the purpose of this study was to determine agreement between circulating biomarkers and FFQ estimated dietary intake in a military population consuming ...
journal_title:Journal of the American College of Nutrition
pub_type: 杂志文章
doi:10.1080/07315724.2018.1490215
更新日期:2019-02-01 00:00:00
abstract:OBJECTIVES:To measure bone mineral density (BMD) and to screen for early biochemical abnormalities in bone mineral metabolism in the first five years of natural menopause when estrogen and calcium supplement are not used and in the absence of major confounding variables. SETTING:Two homogeneous and comparable groups (...
journal_title:Journal of the American College of Nutrition
pub_type: 杂志文章
doi:10.1080/07315724.2005.10719485
更新日期:2005-10-01 00:00:00
abstract::Osteoporosis is a multifactorial disease with dimensions of genetics, endocrine function, exercise and nutritional considerations. Of particular considerations are calcium (Ca) status, Vitamin D, fluoride, magnesium and other trace elements. Several trace elements, particularly copper (Cu), manganese (Mn) and zinc (Zn...
journal_title:Journal of the American College of Nutrition
pub_type: 杂志文章
doi:10.1080/07315724.1993.10718327
更新日期:1993-08-01 00:00:00
abstract:BACKGROUND:Diets containing beans have been associated with a lower risk of obesity and overweight in several dietary surveys. These results suggest a benefit might be derived from beans and other pulses, possibly due to improved satiety or satiation and therefore lowering energy intake. Such a hypothesis has not been ...
journal_title:Journal of the American College of Nutrition
pub_type: 杂志文章,随机对照试验
doi:10.1080/07315724.2009.10719786
更新日期:2009-10-01 00:00:00