Renal response to volume expansion in streptozotocin-induced diabetic rats: influence of calcium channel blockade.

abstract：AIMS:Thiol/disulphide homeostasis plays a critical role in antioxidant defense, and detoxification in body. Although alteration of thiol/disulfide homeostasis had been shown in patients with diabetes, the thiol/disulfide balance in patients with type 2 diabetes and nephropathy is not yet known. METHODS:Twenty-six heal...

journal_title：Diabetes research and clinical practice

authors： Eren MA,Koyuncu İ,İncebıyık H,Karakaş H,Erel Ö,Sabuncu T

更新日期：2019-02-01 00:00:00

abstract：:In the present study, we recruited 124 patients with type 2 diabetes, among which 22 had a history of cardiovascular disease (CVD). The study demonstrated that compared with type 2 diabetes without CVD, those with CVD had remarkably higher levels of angiopoietin-like protein 8 (ANGPTL8). Moreover, the close relationsh...

journal_title：Diabetes research and clinical practice

authors： Huang Y,Fang C,Guo H,Hu J

更新日期：2016-10-01 00:00:00

abstract：BACKGROUND:The aim of this study was to examine the impact of insulin sensitivity and muscle fibre composition to exercise capacity in individuals with type 2 diabetes (T2D), impaired glucose tolerance (IGT) and normal glucose tolerance (NGT). METHODS:Thirty-nine male patients with T2D, 44 male subjects with IGT and 5...

journal_title：Diabetes research and clinical practice

authors： Segerström ÅB,Elgzyri T,Eriksson KF,Groop L,Thorsson O,Wollmer P

更新日期：2011-10-01 00:00:00

abstract：AIMS:Gestational diabetes mellitus (GDM) is associated with adverse obstetrical outcomes and postpartum pre-diabetes/diabetes. As the American Diabetes Association (ADA) criteria for GDM may capture obstetrical risk better than the National Diabetes Data Group (NDDG) criteria, we compared these criteria in their detect...

journal_title：Diabetes research and clinical practice

authors： Retnakaran R,Qi Y,Sermer M,Connelly PW,Zinman B,Hanley AJ

更新日期：2009-07-01 00:00:00

abstract：AIM:Whether exposure to relatively high levels of air pollution is associated with diabetes occurrence remains unclear. We sought to assess and quantify the association between exposure to major air pollutants and risk of type 2 diabetes. METHODS:PubMed and EMBASE databases (through September 2013) were searched using...

journal_title：Diabetes research and clinical practice

authors： Balti EV,Echouffo-Tcheugui JB,Yako YY,Kengne AP

更新日期：2014-11-01 00:00:00

abstract：AIM:To identify characteristics of suboptimally controlled patients with type 2 diabetes (T2DM) on basal insulin treatment who may benefit from intensive titration or further intensification of treatment. METHODS:A post hoc analysis of SOLVE: a 24-week, international, observational study conducted in 17,374 patients w...

journal_title：Diabetes research and clinical practice

authors： Khunti K,Damci T,Husemoen LL,Babu V,Liebl A

更新日期：2017-01-01 00:00:00

abstract：:Considering the nervous system as a unit, it might be expected that diabetic patients with autonomic neuropathy could have a central abnormality expressed as cognitive dysfunction. To determine whether autonomic neuropathy is independently associated with cognitive dysfunction, we studied a cross-section of 20 non-ins...

journal_title：Diabetes research and clinical practice

authors： Zaslavsky LM,Gross JL,Chaves ML,Machado R

更新日期：1995-11-01 00:00:00

abstract：:There is a higher incidence of stroke in both the type 2 diabetic and the non-diabetic insulin resistant patient which is accompanied by higher morbidity and mortality. Stroke primary prevention can be achieved by controlling atrial fibrillation and hypertension, and the utilization of statins and anticoagulant therap...

journal_title：Diabetes research and clinical practice

authors： Bell DSH,Goncalves E

更新日期：2020-06-01 00:00:00

abstract：:A large-scale isolation of islets is required for islet transplantation. We improved our conventional method, and could obtain about three times more islets than by the conventional methods. Pancreata of adult Wistar rats were inflated by injection of buffer with (A) or without 1.3 mg/ml collagenase (B). The rats were...

journal_title：Diabetes research and clinical practice

authors： Hara Y,Taniguchi H,Ishihara K,Ejiri K,Tsutou A,Narutaki K,Baba S

更新日期：1989-02-15 00:00:00

abstract：:Our aim was to see the levels of lipoprotein (a) (Lp (a)) in patients with gangrenous or non-gangrenous diabetic foot lesions. Twenty-two patients with gangrenous foot lesions, 11 with non-gangrenous foot lesions and 10 healthy subjects were included in the study. All the patients had similar glycemic control and dura...

journal_title：Diabetes research and clinical practice

authors： Unlühizarci K,Muhtaroğlu S,Kabak S,Bayram F,Keleştimur F

更新日期：2006-02-01 00:00:00

abstract：OBJECTIVE:The prevalence of treatment resistant hypertension (RH) depends on methods used for blood pressure (BP) measurements, goals of BP, and therapeutic efforts in terms of medication and adherence. We focused on diabetic subjects and explored the prevalence of RH in primary care practice. METHODS:In 1737 subjects...

journal_title：Diabetes research and clinical practice

authors： Yokoyama H,Araki S,Watanabe S,Honjo J,Okizaki S,Yamada D,Shudo R,Shimizu H,Sone H,Haneda M

更新日期：2015-10-01 00:00:00

abstract：:Administration of insulin with premeal boluses of short-acting insulin using a new injection device (Novopen) was compared with a conventional three times daily injection regimen regarding aspects of quality of life and metabolic control in insulin-dependent diabetes mellitus (IDDM). Eighteen C-peptide-negative patien...

journal_title：Diabetes research and clinical practice

authors： Tallroth G,Karlson B,Nilsson A,Agardh CD

更新日期：1989-01-03 00:00:00

abstract：AIMS:To compare the feasibility of high intensity interval exercise (HI-IE) versus moderate intensity continuous exercise (MI-CE) in patients with type 2 diabetes (T2D), and to investigate the preliminary efficacy of HI-IE and MI-CE for improving glycated hemoglobin A1c (HbA1c) and body composition. METHODS:Individual...

journal_title：Diabetes research and clinical practice

authors： Terada T,Friesen A,Chahal BS,Bell GJ,McCargar LJ,Boulé NG

更新日期：2013-02-01 00:00:00

abstract：:The study analyzed the clinical background and eating habits of Japanese youth-onset type 2 diabetes. Thirty-six patients with type 2 diabetes (22 males, 14 females) with onset in less than 20-year-old were studied. All patients were negative for anti-glutamic acid decarboxylase (GAD) antibody and islet cell antibody....

journal_title：Diabetes research and clinical practice

authors： Matsui J,Tamasawa N,Tanabe J,Kasai N,Murakami H,Matsuki K,Suda T

更新日期：2005-12-01 00:00:00

abstract：:We report a case of chronic hepatitis C presenting insulin-dependent diabetes mellitus (IDDM) associated with various autoantibodies including possible anti-insulin receptor antibody (AIRA) during interferon (IFN) therapy. A 57-year-old man having chronic hepatitis C virus (HCV) infection with chronic thyroiditis rece...

journal_title：Diabetes research and clinical practice

authors： Uto H,Matsuoka H,Murata M,Okamoto T,Miyata Y,Hori T,Ido A,Hirono S,Hayashi K,Tsubouchi H

更新日期：2000-08-01 00:00:00

abstract：:We observed that in isolated perfused rat kidneys, sphingosine-1-phosphate produces S1P(2) receptor-mediated vasoconstriction, and this response increased in kidneys of diabetic rats. These results suggest that the antagonists of S1P(2) receptor may have potential as drugs to control diabetes-induced vascular complica...

journal_title：Diabetes research and clinical practice

authors： Bautista-Pérez R,Arellano A,Franco M,Osorio H,Coronel I

更新日期：2011-10-01 00:00:00

abstract：:We report a case of nephrotic syndrome complicating pregnancy in a woman with CSII-treated type 1 diabetes. This was associated with deteriorating glycaemic control which was successfully managed with continuous intravenous insulin for the two weeks before delivery. ...

journal_title：Diabetes research and clinical practice

authors： Dudding S,Whitelaw D

更新日期：2011-07-01 00:00:00

abstract：:To explore the functional effects of hormone-sensitive lipase (HSL) in diacylglycerol (DAG) metabolism, Chinese hamster ovary cells were stably transfected with rat HSL cDNA (wt-HSL), inactive mutant S423A-HSL cDNA (S423A) and pcDNA3 vector alone (Ct). [(14)C]Glucose-incorporation into triglyceride (TG) was 75% lower ...

journal_title：Diabetes research and clinical practice

authors： Kanehara H,Suzuki J,Zenimaru Y,Takahashi S,Oida K,Shen WJ,Kraemer FB,Miyamori I

更新日期：2004-09-01 00:00:00

abstract：AIMS:Insulin resistance (IR) detection is challenging and no test is currently used in clinical practice. We developed salivary biomarkers that could be used for IR detection. METHODS:We collected saliva from 186 healthy and 276 pre-diabetic participants, divided them into high and low IR groups based on a HOMA cutoff...

journal_title：Diabetes research and clinical practice

authors： Zhang Y,Sun J,Li F,Grogan TR,Vergara JL,Luan Q,Park MS,Chia D,Elashoff D,Joshipura KJ,Wong DTW

更新日期：2017-10-01 00:00:00

abstract：:Serum insulin 1 h post-glucose load is examined in this prospective study of 2971 Caucasoid subjects aged > 20 years in 1966 and followed to 1989. The serum insulin levels as a continuous variable show no significant linear association with coronary heart disease (CHD) deaths in either sex after accounting for age by ...

journal_title：Diabetes research and clinical practice

authors： Welborn TA,Knuiman MW,Ward N,Whittall DE

更新日期：1994-11-01 00:00:00

abstract：:We evaluated the effects of thromboxane synthetase inhibitor, OKY-046, on urinary albumin and prostaglandin (PG) excretion in 14 patients with non-insulin-dependent diabetes mellitus (NIDDM). Urinary excretion of 6-keto-PGF1 alpha (a stable metabolite of PGI2), TXB2 (a stable metabolite of TXA2) and PGE2 in NIDDM pati...

journal_title：Diabetes research and clinical practice

authors： Tajiri Y,Inoguchi T,Umeda F,Nawata H

更新日期：1990-11-01 00:00:00

abstract：BACKGROUND:The study aims were to estimate the incidence and risk factors for T2D in four settings with different degree of urbanization and altitude in Peru. METHODS:Prospective cohort study conducted in urban, semi-urban, and rural areas in Peru. An age- and sex-stratified random sample of participants was taken fro...

journal_title：Diabetes research and clinical practice

authors： Bernabé-Ortiz A,Carrillo-Larco RM,Gilman RH,Miele CH,Checkley W,Wells JC,Smeeth L,Miranda JJ,CRONICAS Cohort Study Group.

更新日期：2016-11-01 00:00:00

abstract：:Apoptosis and its associated regulatory mechanisms are physiological events crucial to the maintenance of placental homeostasis; imbalance of these processes, however, such as occurs under various pathological conditions, may compromise placenta function and, consequently, pregnancy success. Increased apoptosis occurs...

journal_title：Diabetes research and clinical practice

authors： Sgarbosa F,Barbisan LF,Brasil MA,Costa E,Calderon IM,Gonçalves CR,Bevilacqua E,Rudge MV

更新日期：2006-08-01 00:00:00

abstract：OBJECTIVE:This study was conducted to assess the adverse effects of diabetic nephropathy on cardiovascular autonomic neuropathy (CAN) in South Indian Type 2 diabetic patients. METHODS:Comparison was made between Type 2 diabetic patients with nephropathy (group 1, n=25), Type 2 diabetic patients without nephropathy (gr...

journal_title：Diabetes research and clinical practice

authors： Viswanathan V,Prasad D,Chamukuttan S,Ramachandran A

更新日期：2000-06-01 00:00:00

abstract：:The Africa Region (AFR), where diabetes was once rare, has witnessed a surge in the condition. Estimates for type 1 diabetes suggest that about 39,000 people suffer from the disease in 2013 with 6.4 new cases occurring per year per 100,000 people in children <14 years old. Type 2 diabetes prevalence among 20-79-year-o...

journal_title：Diabetes research and clinical practice

authors： Peer N,Kengne AP,Motala AA,Mbanya JC

更新日期：2014-02-01 00:00:00

abstract：:A low-carbohydrate/high-fat evening meal impaired the glucose tolerance of healthy subjects to almost the same extent as the impairment caused by overnight fasting. This suggests that the decreased component (carbohydrate) is more relevant than the increased component (fat) to the impairment of glucose tolerance by a ...

journal_title：Diabetes research and clinical practice

authors： Wang Y,Kaneko T,Wang PY,Sato A

更新日期：2002-01-01 00:00:00

abstract：AIMS:Although serum complement factor 3 (C3) is an acute phase reactant mainly synthesized in the liver, several recent studies have shown high C3 gene expression in adipose tissue (AT). However, the relationship between C3 and AT levels has not been fully clarified in type 2 diabetes mellitus (T2DM) patients. METHODS...

journal_title：Diabetes research and clinical practice

authors： Nishimura T,Itoh Y,Yamashita S,Koide K,Harada N,Yano Y,Ikeda N,Azuma K,Atsumi Y

更新日期：2017-05-01 00:00:00

abstract：:Experimental data support a role for insulin and insulin-like growth factor-I (IGF-I) in the pathophysiology of vascular complications in diabetes. Clinical data for both hormones are less convincing, mainly because the various studies vary in methodologies, sample sizes, and populations. So far, by epidemiological me...

journal_title：Diabetes research and clinical practice

authors： Göke B,Fehmann HC

更新日期：1996-02-01 00:00:00

abstract：:We ascertained frequencies of autoantibodies to a suite of islet cell antigens including ICA512/IA2 and SOX13 in Asian Indians with Type 1 diabetes and in other forms of diabetes. Autoantibodies to ICA512/IA2 and SOX13 were tested by radioimmunoprecipitation assay, and results were amalgamated with previous data on an...

journal_title：Diabetes research and clinical practice

authors： Fida S,Myers M,Mackay IR,Zimmet PZ,Mohan V,Deepa R,Rowley MJ

更新日期：2001-06-01 00:00:00

abstract：OBJECTIVE:To investigate the changes of serum anti-aging protein Klotho and neutrophil gelatinase-associated lipocalin (NGAL) levels and their correlation in type 2 diabetes mellitus (T2DM) patients at different stages of diabetic kidney disease (DKD) determined by urinary albuminuria. METHODS:462 cases with T2DM were...

journal_title：Diabetes research and clinical practice

authors： Wu C,Wang Q,Lv C,Qin N,Lei S,Yuan Q,Wang G

更新日期：2014-11-01 00:00:00