Abstract：
:Blood pressure (BP) during siesta declines to levels similar to those of night time sleep. The objective of the study was to assess the effect of siesta on 24-h ambulatory BP (ABP) data. Two different approaches were employed for the definition of day and night periods: (1) actual patient reported day and night intervals (ACT) with siesta period analysed as a third time period; and (2) arbitrary day and night time intervals (ARB) with the presence of siesta being ignored. A total of 203 24-h ABP recordings were analysed, with a siesta during ABP monitoring reported in 154 of them. Mean siesta BP was very close to ACT night time BP. Among recordings with a siesta, ACT daytime BP was higher and night time BP lower than the corresponding ARB BPs (P < 0.001). The magnitude of night time BP drop was greater with ACT intervals, resulting in a lower percentage of non-dippers (P < 0.001). Among 49 recordings without a siesta, differences between ACT and ARB BPs were less pronounced for daytime but not for night time. Differences in the magnitude of nocturnal BP drop between ACT and ARB periods, although statistically significant, did not affect the prevalence of non-dippers. In conclusion, analysis of 24-h BP profiles by using ARB instead of ACT day and night intervals results in underestimation of the nocturnal BP drop and overestimation of the proportion of non-dippers. This bias is more pronounced in patients who take a siesta during ABP monitoring.
journal_name
J Hum Hypertensjournal_title
Journal of human hypertensionauthors
Stergiou GS,Malakos JS,Zourbaki AS,Achimastos AD,Mountokalakis TDdoi
10.1038/sj.jhh.1000383subject
Has Abstractpub_date
1997-02-01 00:00:00pages
125-31issue
2eissn
0950-9240issn
1476-5527journal_volume
11pub_type
杂志文章abstract：:The level of blood pressure, the type of antihypertensive treatment and the prevalence of resistant hypertension at the first examination were evaluated in 6254 patients referred to a hospital Hypertension Unit from 1989 to 2003. From 1989-1993 to 1999-2003, we observed a reduced prevalence of grade 2 and grade 3 hype...
journal_title：Journal of human hypertension
pub_type： 信件
doi：10.1038/sj.jhh.1002285
更新日期：2008-02-01 00:00:00
abstract：:Sympathetic activation has been associated with the development and complications of hypertension. While the prevalence of hypertension and its cardiovascular risks in women are found to be less than in men and tend to become similar to men after the menopause, there have been no data on the level of sympathetic activ...
journal_title：Journal of human hypertension
pub_type： 杂志文章
doi：10.1038/jhh.2008.31
更新日期：2008-08-01 00:00:00
abstract：:Hypertension is strongly influenced by genetic factors. Although hypertension prevalence in some Hispanic sub-populations is greater than in non-Hispanic whites, genetic studies on hypertension have focused primarily on samples of European descent. A recent meta-analysis of 200 000 individuals of European descent iden...
journal_title：Journal of human hypertension
pub_type： 杂志文章,meta分析,多中心研究
doi：10.1038/jhh.2016.29
更新日期：2016-12-01 00:00:00
abstract：:Hypertension is regarded as a major contributor to vascular disease. Vascular disease is a fairly common denominator in a large percentage of cases of dementia. Despite this strong connecting link, dementia is often not considered as a mainstream problem consequent to hypertension, though there is an alarming increase...
journal_title：Journal of human hypertension
pub_type： 杂志文章,评审
doi：10.1038/s41371-019-0205-z
更新日期：2019-08-01 00:00:00
abstract：:Chronic dynamic (aerobic) exercise decreases central arterial stiffness, whereas chronic resistance exercise evokes the opposite effect. Nevertheless, there is little information available on the effects of acute bouts of exercise. Also, there is limited data showing an increase of central arterial stiffness during ac...
journal_title：Journal of human hypertension
pub_type： 杂志文章
doi：10.1038/jhh.2008.4
更新日期：2008-05-01 00:00:00
abstract：:Large-artery stiffness is a risk factor for stroke, including cerebral small-vessel disease. Retinal microvascular changes are thought to mirror those in cerebral microvessels. We investigated the relationship between aortic stiffness and retinal microvascular changes in Asian ischemic stroke patients. We studied 145 ...
journal_title：Journal of human hypertension
pub_type： 杂志文章
doi：10.1038/jhh.2011.88
更新日期：2012-12-01 00:00:00
abstract：:Stroke is a very common cause of death and disability. Several lines of evidence point to stroke as a polygenic multifactoral phenotype and there are also a number of well studied single gene Mendelian stroke conditions. Rat models have identified several chromosomal sites linked to stroke, and this together with othe...
journal_title：Journal of human hypertension
pub_type： 杂志文章,评审
doi：10.1038/sj.jhh.1000486
更新日期：1997-09-01 00:00:00
abstract：:The aims of this study were to determine: (1) the proportion of elderly hypertensive subjects currently attending a hospital hypertension clinic suitable for a trial of antihypertensive drug withdrawal, (2) the proportion of suitable patients who can be successfully withdrawn from drug therapy while receiving nonpharm...
journal_title：Journal of human hypertension
pub_type： 杂志文章
doi：
更新日期：1994-11-01 00:00:00
abstract：:A study was undertaken in 298 normotensive, normolipidaemic and normoglycaemic subjects to define the range of erythrocyte sodium-lithium countertransport activity in this cohort and to determine the associations between countertransport activity and markers of vascular risk. Countertransport activity showed a positiv...
journal_title：Journal of human hypertension
pub_type： 杂志文章
doi：
更新日期：1995-07-01 00:00:00
abstract：:Hypertension is a major risk factor for cardiovascular disease, which is the leading cause of mortality in women in developed countries. This pooled analysis assessed the antihypertensive efficacy, safety and tolerability of monotherapy with the direct renin inhibitor aliskiren (150 mg and 300 mg) over 8-12 weeks in w...
journal_title：Journal of human hypertension
pub_type： 杂志文章,meta分析
doi：10.1038/jhh.2010.11
更新日期：2010-11-01 00:00:00
abstract：:Established essential hypertension is characterised haemodynamically by a normal cardiac output and elevated total peripheral resistance. As hypertensive cardiovascular disease progresses, and the patient grows older, cardiac output falls and total peripheral resistance is further elevated. The activity of the renin-a...
journal_title：Journal of human hypertension
pub_type： 杂志文章,评审
doi：
更新日期：1989-06-01 00:00:00
abstract：:Until now, no information is available about the effect of the presence of a doctor-in-training on a patient's blood pressure. We tested the hypothesis that the presence of a last year medical student might increase the blood pressure of the patient, in addition to the possible pressor response to the doctor-trainer. ...
journal_title：Journal of human hypertension
pub_type： 临床试验,杂志文章,多中心研究,随机对照试验
doi：10.1038/sj.jhh.1001744
更新日期：2004-11-01 00:00:00
abstract：:Hypertension in women has received less attention than hypertension in men, and the major controlled trials of antihypertensive therapy have been carried out in populations made up predominantly of and have emphasised outcomes in men. Recently it has been recognised that women develop high blood pressure, particularly...
journal_title：Journal of human hypertension
pub_type： 杂志文章,评审
doi：10.1038/sj.jhh.1001095
更新日期：2000-10-01 00:00:00
abstract：:We tested the utility of qualitative microalbuminuria (MAU) screening in an office practice setting, in assessing the response of MAU to drug treatment. We enrolled general practitioners throughout Germany, who obtained histories, physical examinations, and routine laboratory values as clinically indicated on > 6000 n...
journal_title：Journal of human hypertension
pub_type： 杂志文章
doi：
更新日期：1996-08-01 00:00:00
abstract：:The objective of the study is to compare fatal and nonfatal cardiovascular endpoints in hypertensive patients randomised to the calcium-channel blocker, nifedipine GITS or a thiazide diuretic, co-amilozide. A total of 6592 patients from nine countries (UK, France, Israel, Spain, Italy, The Netherlands, Sweden, Denmark...
journal_title：Journal of human hypertension
pub_type： 临床试验,杂志文章,随机对照试验
doi：
更新日期：1996-09-01 00:00:00
abstract：:Losartan, enalapril and amlodipine reduced the number of premature ventricular contractions (PVCs) in patients with essential hypertension as well as blood pressure. The effect of losartan was the most prominent among the three drugs. ...
journal_title：Journal of human hypertension
pub_type： 临床试验,信件
doi：10.1038/jhh.2008.122
更新日期：2009-04-01 00:00:00
abstract：:In view of the concern regarding the potential risks and benefits of sodium restriction, the effect on biochemical and orthostatic responses from a moderate reduction in sodium intake in elderly persons that is sufficient to lower systolic blood pressure (SBP) was examined. Seventeen hypertensive subjects aged 65-79 y...
journal_title：Journal of human hypertension
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1038/sj.jhh.1000436
更新日期：1997-06-01 00:00:00
abstract：:Large-scale trials with angiotensin converting enzyme (ACE) inhibitors and angiotensin II type 1 (AT(1))-receptor blockers have clearly shown that blockade of the renin-angiotensin system reduces the deterioration in renal function associated with diabetes. AT(1)-receptor blockers represent a more rational approach to...
journal_title：Journal of human hypertension
pub_type： 杂志文章,评审
doi：10.1038/sj.jhh.1001441
更新日期：2002-08-01 00:00:00
abstract：:For the epidemiologist, the development of any new therapy or strategy must respond to the following three questions: does a need exist? Is there a new way of meeting that need? Can a valid assessment be made of the efficacy of the new therapy? New antihypertensive treatments or strategies are needed, even in 1994: in...
journal_title：Journal of human hypertension
pub_type： 杂志文章,评审
doi：
更新日期：1995-08-01 00:00:00
abstract：:It has been suggested that the deletion polymorphism of the angiotensin-converting enzyme (ACE) genotype may be important in the development of left ventricular hypertrophy (LVH). In order to test this hypothesis we investigated the interaction between blood pressure (BP), LVH and ACE genotype in 86 previously untreat...
journal_title：Journal of human hypertension
pub_type： 杂志文章
doi：10.1038/sj.jhh.1000491
更新日期：1997-09-01 00:00:00
abstract：:The aim of the study was to investigate the impact of various blood pressure (BP) measurement methods on the assessment of differences in BP levels between patients with normoalbuminuric type 1 diabetes and healthy controls. We measured intra-arterial BP (i.a.), sphygmomanometric BP (sphygmo), 24-h ambulatory blood pr...
journal_title：Journal of human hypertension
pub_type： 临床试验,杂志文章
doi：10.1038/sj.jhh.1000776
更新日期：1999-02-01 00:00:00
abstract：:Studies of populations or communities with no rise in blood pressure (BP) with advancing age and low prevalence of hypertension, may provide aetiological clues on the cause of hypertension. Within westernised societies, low blood pressures have been reported amongst chronic psychiatric in-patients and closed order sec...
journal_title：Journal of human hypertension
pub_type： 杂志文章
doi：10.1038/sj.jhh.1000853
更新日期：1999-07-01 00:00:00
abstract：:The systemic oxidative status in hypertensives disorders of pregnancy (HDP) and its association with endothelial dysfunction is controversial. In the present study, we evaluated systemic plasma levels of oxidative stress markers (TBARS (thiobarbituric acid-reactive substances) and carbonyl) and total antioxidant statu...
journal_title：Journal of human hypertension
pub_type： 杂志文章
doi：10.1038/jhh.2012.58
更新日期：2013-06-01 00:00:00
abstract：:Both brachial blood pressure (BP) level and its variability (BPV) significantly associate with left ventricular (LV) structure and function. Recent studies indicate that aortic BP is superior to brachial BP in the association with LV abnormalities. However, it remains unknown whether aortic BPV better associate with L...
journal_title：Journal of human hypertension
pub_type： 杂志文章
doi：10.1038/jhh.2017.37
更新日期：2017-10-01 00:00:00
abstract：:Little is known about how aortic waveform parameters vary with ethnicity and lifestyle factors. We investigated these issues in a large, population-based sample. We carried out a cross-sectional analysis of 4798 men and women, aged 50-84 years from Auckland, New Zealand. Participants were 3961 European, 321 Pacific, 2...
journal_title：Journal of human hypertension
pub_type： 杂志文章
doi：10.1038/jhh.2016.78
更新日期：2017-05-01 00:00:00
abstract：:This article reviews the current literature regarding the role of home measurement of blood pressure (BP) in the management of hypertension. Subjects with hypertension can use simple automated devices to measure their own BP at home. The results can be accurate and reliable, and because multiple readings allow a mean ...
journal_title：Journal of human hypertension
pub_type： 杂志文章,评审
doi：10.1038/sj.jhh.1001423
更新日期：2002-07-01 00:00:00
abstract：:The renin-angiotensin system is central to the pathophysiology of a number of cardiovascular disorders. Most obviously this is so with renin secreting tumours, but the system is of central importance in other disorders such as scleroderma renal crisis and most cases of malignant hypertension. Activation of the renin-a...
journal_title：Journal of human hypertension
pub_type： 杂志文章,评审
doi：10.1038/sj.jhh.1000638
更新日期：1998-05-01 00:00:00
abstract：:Haemorrhagic diathesis develops in chronic renal failure, in which calcium antagonists are used widely as antihypertensive agents. Although calcium antagonists are reported to impair platelet function, it has not been examined whether calcium antagonists alter bleeding time. The present study was conducted to clarify ...
journal_title：Journal of human hypertension
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1038/sj.jhh.1001327
更新日期：2002-03-01 00:00:00
abstract：:Elevated visit-to-visit blood pressure variability (BPV), independent of mean BP, has been associated with cardiovascular events. However, its impact after ST-elevation myocardial infarction (STEMI) has not been established. This study aimed to investigate the prognostic impact of BPV on patients after STEMI. We analy...
journal_title：Journal of human hypertension
pub_type： 杂志文章
doi：10.1038/s41371-019-0176-0
更新日期：2019-04-01 00:00:00
abstract：:The E/A ratio (of peak mitral blood flow velocity during early diastole to that during atrial contraction) has limitations in the assessment of diastolic function. Previous studies have suggested that peak blood flow velocity is normally maintained or increased towards the cardiac apex but that it decreases in diastol...
journal_title：Journal of human hypertension
pub_type： 临床试验,杂志文章
doi：10.1038/sj.jhh.1000905
更新日期：1999-12-01 00:00:00
