Losartan decreased premature ventricular contractions in patients with hypertension.

abstract：:Candesartan cilexetil is rapidly and completely hydrolysed to the active compound candesartan during absorption from the gastrointestinal tract. Candesartan is a potent, long-acting, selective angiotensin II AT1 receptor blocker. The pharmacokinetics of candesartan were investigated after single and repeated once-dail...

journal_title：Journal of human hypertension

authors： Hübner R,Högemann AM,Sunzel M,Riddell JG

更新日期：1997-09-01 00:00:00

abstract：:Nineteen patients with essential hypertension on regular treatment with nifedipine tablets 20 mg twice daily and whose DBP was < 95 mmHg on at least two occasions two weeks apart were entered in a double-blind randomised crossover study of three weeks treatment with nifedipine coat core (new formulation) either as 30 ...

journal_title：Journal of human hypertension

authors： Missouris CG,Cappuccio FP,Markandu ND,Singer DR,MacGregor GA

更新日期：1994-04-01 00:00:00

abstract：:Prevalence, awareness, treatment and control of hypertension were assessed in 1032 (90%) of 1147 elderly (> or = 65 years) inhabitants of three Italian villages. Blood pressure (BP) was measured at home on two separate occasions following a standardised protocol. Persons taking antihypertensive drugs or with BP values...

journal_title：Journal of human hypertension

authors： Prencipe M,Casini AR,Santini M,Ferretti C,Scaldaferri N,Culasso F

更新日期：2000-12-01 00:00:00

abstract：:The African population is considered a high-risk group for the development of hypertension, and identifying risk factors are therefore essential in preventive actions against cardiovascular disease (CVD). Elevated levels of uric acid (UA) are often associated with CVD. Our first aim was to establish possible ethnic di...

journal_title：Journal of human hypertension

authors： Palmer IM,Schutte AE,Huisman HW

更新日期：2010-10-01 00:00:00

abstract：:A 16 year old boy presented with accelerated hypertension and urinary tract obstruction caused by phimosis. Relief of the obstruction by circumcision reversed the hypertension. We believe that accelerated hypertension secondary to phimosis has not previously been described. ...

journal_title：Journal of human hypertension

authors： Robinson FO,Johnston SR,Atkinson AB

更新日期：1992-04-01 00:00:00

abstract：:To investigate a possible association between miR-101 and apoptosis of human trophoblast cells mediated by endoplasmic reticulum protein 44 (ERp44) in preeclampsia (PE), we explored the expression of miR-101 in PE placentas (n=30) compared with normotensive pregnant placentas (n=30) and the correlation between miR-101...

journal_title：Journal of human hypertension

authors： Zou Y,Jiang Z,Yu X,Zhang Y,Sun M,Wang W,Ge Z,De W,Sun L

更新日期：2014-10-01 00:00:00

abstract：:Large-artery stiffness is a risk factor for stroke, including cerebral small-vessel disease. Retinal microvascular changes are thought to mirror those in cerebral microvessels. We investigated the relationship between aortic stiffness and retinal microvascular changes in Asian ischemic stroke patients. We studied 145 ...

journal_title：Journal of human hypertension

authors： De Silva DA,Woon FP,Manzano JJ,Liu EY,Chang HM,Chen C,Wang JJ,Mitchell P,Kingwell BA,Cameron JD,Lindley RI,Wong TY,Wong MC,behalf of the Multi-Centre Retinal Stroke Study Collaborative Group.

更新日期：2012-12-01 00:00:00

abstract：:To investigate blood pressure (BP) as well as other risk factors before the onset of myocardial infarction in hypertensive patients, we analysed the BP and metabolic variables in 94 hypertensive patients who had been followed up in our out-patient clinic before the first onset (M1 group; n = 42, 69 +/- 1 years, mean +...

journal_title：Journal of human hypertension

authors： Minami J,Kawano Y,Nonogi H,Ishimitsu T,Matsuoka H,Takishita S

更新日期：1998-10-01 00:00:00

abstract：:Electrocardiograph (ECG) criteria for left ventricular hypertrophy (LVH) are a widely used clinical tool. We recalibrated six ECG criteria for LVH against gold-standard cardiac magnetic resonance (CMR) and assessed the impact of obesity. One hundred and fifty consecutive tertiary hypertension clinic referrals for CMR ...

journal_title：Journal of human hypertension

authors： Rodrigues JC,McIntyre B,Dastidar AG,Lyen SM,Ratcliffe LE,Burchell AE,Hart EC,Bucciarelli-Ducci C,Hamilton MC,Paton JF,Nightingale AK,Manghat NE

更新日期：2016-03-01 00:00:00

abstract：:The level of blood pressure, the type of antihypertensive treatment and the prevalence of resistant hypertension at the first examination were evaluated in 6254 patients referred to a hospital Hypertension Unit from 1989 to 2003. From 1989-1993 to 1999-2003, we observed a reduced prevalence of grade 2 and grade 3 hype...

journal_title：Journal of human hypertension

authors： Leotta G,Rabbia F,Canadè A,Testa E,Papotti G,Mulatero P,Veglio F

更新日期：2008-02-01 00:00:00

abstract：:Primary aldosteronism (PA), the most common cause of secondary hypertension, is a well-recognized condition that can lead to cardiovascular and renal complications. PA is frequently left undiagnosed and untreated, leading to aldosterone-specific morbidity and mortality. In this review we highlight the evidence linking...

journal_title：Journal of human hypertension

authors： Loh HH,Sukor N

更新日期：2020-01-01 00:00:00

abstract：:This report analysed data from the Health Survey for England 1994 to evaluate blood pressure (BP) management in relation to cigarette smoking. Data were analysed for 12 013 adults aged > or = 16 years living in England in 1994. Among 2280 subjects with BP > or = 160/95 mm Hg or treated with BP-lowering medication, rat...

journal_title：Journal of human hypertension

authors： Gulliford MC

更新日期：2001-11-01 00:00:00

abstract：:The pathological myocardial hypertrophy associated with hypertension contains the seed for further maladaptive development. Increased myocardial oxygen consumption, impaired epicardial coronary perfusion, ventricular fibrosis and remodelling, abnormalities in long-axis function and torsion, cause, to a varying degree,...

journal_title：Journal of human hypertension

authors： Yip GW,Fung JW,Tan YT,Sanderson JE

更新日期：2009-05-01 00:00:00

abstract：:The aim of this study was to assess the effect of alcohol on blood pressure and arterial compliance over 24 h in a group of volunteers, comparing the same group of subjects on two consecutive but separate days, one with alcohol intake (alcohol day) and one free of alcohol (control day). We studied 18 healthy subjects ...

journal_title：Journal of human hypertension

authors： Fantin F,Bulpitt CJ,Zamboni M,Cheek E,Rajkumar C

更新日期：2016-01-01 00:00:00

abstract：:Epidemiological studies demonstrated that Helicobacter pylori (H. pylori) infection was associated with cardiovascular disease and its risk factors. However, the association between H. pylori infection and hypertension remained unclear. The aim of this study was to investigate the association between H. pylori infecti...

journal_title：Journal of human hypertension

authors： Wan Z,Hu L,Hu M,Lei X,Huang Y,Lv Y

更新日期：2018-02-01 00:00:00

abstract：:It is rare for a study to address immediate metabolic change in pre-eclamptic pregnancy. Our aim is to study the ante-partum and post-partum metabolic markers in pre-eclampsia. A total of 33 pre-eclamptic and 200 uncomplicated women with singleton pregnancies were recruited for the prospective research. Immediately an...

journal_title：Journal of human hypertension

authors： Lei Q,Lv LJ,Zhang BY,Wen JY,Liu GC,Lin XH,Niu JM

更新日期：2011-01-01 00:00:00

abstract：:We evaluated the relationship between renal resistive index (RRI) of the intrarenal vasculature and cardiovascular (CV) organ damage such as left ventricular hypertrophy (LVH), diastolic dysfunction and carotid atherosclerosis in a large sample of hypertensive patients. 566 hypertensive patients underwent echocardiogr...

journal_title：Journal of human hypertension

authors： Tedesco MA,Natale F,Mocerino R,Tassinario G,Calabrò R

更新日期：2007-04-01 00:00:00

abstract：:The aim of this study was to ascertain the relationship between social network and the appearance of mortality (cardiovascular events (CVEs)) in patients with arterial hypertension (AHT). This is a cohort study of 236 patients with a 9-year follow-up. Measurements included age, sex, blood pressure (BP), diabetes, hype...

journal_title：Journal of human hypertension

authors： Menéndez-Villalva C,Gamarra-Mondelo MT,Alonso-Fachado A,Naveira-Castelo A,Montes-Martínez A

更新日期：2015-07-01 00:00:00

abstract：:The C(-344)T promoter polymorphism of the human aldosterone synthase (CYP11B2) gene has been associated with hypertension and cardiac hypertrophy, but there were contrasting data. We analysed the genotype/phenotype associations between this polymorphism and cardiovascular variables in a young adult population, where i...

journal_title：Journal of human hypertension

authors： Sarzani R,Salvi F,Dessì-Fulgheri P,Catalini R,Mazzara D,Cola G,Siragusa N,Spagnolo D,Ercolani P,Gesuita R,Carle F,Rappelli A

更新日期：2003-12-01 00:00:00

abstract：:An increasing of arterial stiffness is the path physiological characteristic of hypertension. Cardio-ankle vascular index (CAVI) is a new index of arterial stiffness. In the present study, we investigated the relationship between CAVI and plasma lipids in hypertension subjects. A total of 542 subjects (male/female 336...

journal_title：Journal of human hypertension

authors： Wang H,Liu J,Zhao H,Zhao X,Li L,Shi H,Zhan S,Liu J

更新日期：2015-02-01 00:00:00

abstract：:Angiotensin-converting enzyme (ACE) levels and ACE gene polymorphisms have been related with hypertension but with contradictory results between populations. We have investigated the association among the allelic distribution of the insertion-deletion (I/D) polymorphism of the ACE gene, identified by polymerase chain ...

journal_title：Journal of human hypertension

authors： Martínez E,Puras A,Escribano J,Sanchis C,Carrión L,Artigao M,Divisón JA,Massó J,Vidal A,Fernández JA

更新日期：2000-02-01 00:00:00

abstract：:This study recruited 85 healthy children and adolescents, aged 6-18 years, from a school-based blood pressure (BP) screening study and performed office BP measurements, 24-h ambulatory blood pressure monitoring (24-h ABPM) and 24-h pulse wave analysis. Prevalence of BP phenotypes was assessed, factors that may predict...

journal_title：Journal of human hypertension

authors： Kollios K,Nika T,Kotsis V,Chrysaidou K,Antza C,Stabouli S

更新日期：2021-01-01 00:00:00

abstract：:Since endothelin production is stimulated in vitro by insulin, we performed this study to evaluate in vivo the relationships between endothelin and insulin plasma levels during a glucose load. We studied 28 subjects; 17 with normal glucose tolerance (NGT) and 11 with impaired glucose tolerance (IGT). Ten of the subjec...

journal_title：Journal of human hypertension

authors： Andronico G,Mangano M,Ferrara L,Lamanna D,Mulé G,Cerasola G

更新日期：1997-01-01 00:00:00

abstract：:Clinical studies have shown that aldosterone and salt are independently related to hypertension, cardiovascular morbidity and mortality. More recently, studies in humans have demonstrated that, similarly to animals, endogenous aldosterone and dietary salt intake have not only separate, but also combined effects to acc...

journal_title：Journal of human hypertension

authors： Pimenta E,Gordon RD,Stowasser M

更新日期：2013-01-01 00:00:00

abstract：:The objective of this study was to determine the electrocardiographic left ventricular hypertrophy (LVH) criterion that best correlated with vascular structure and function parameters in hypertensive patients. A cross-sectional study involving 347 hypertensive patients was performed. The mean age of the subjects was 5...

journal_title：Journal of human hypertension

authors： Gómez-Marcos MA,Recio-Rodríguez JI,Patino-Alonso MC,Agudo-Conde C,Rodríguez-Sánchez E,Gómez-Sánchez L,Gómez-Sánchez M,García-Ortiz L,Vaso risk group.

更新日期：2014-03-01 00:00:00

abstract：:When captopril was first introduced for the management of hypertension, its short plasma half-life led to its use as a thrice daily regimen. However, further experience suggests that the biological action is more prolonged than the plasma half-life might suggest. This study examined the effect of varying the frequency...

journal_title：Journal of human hypertension

authors： Conway J,Way B,Boon N,Somers V

更新日期：1988-08-01 00:00:00

abstract：BACKGROUND:Hypertension is associated with increased urinary calcium excretion (UCa). A high sodium intake increases both UCa and blood pressure (BP). However, it is not clear whether these effects are modified by gender or ethnic origin. OBJECTIVES:To examine the relationships between BP, urinary sodium (UNa), gender...

journal_title：Journal of human hypertension

authors： Blackwood AM,Sagnella GA,Cook DG,Cappuccio FP

更新日期：2001-04-01 00:00:00

abstract：:Both trandolapril and verapamil are effective and widely used antihypertensive agents. The aim of this study was to estimate the efficacy and tolerability of trandolapril/verapamil (Tr/Ve) combination for blood pressure control and renoprotection. PubMed, EMBASE and Cochrane Library were searched for relevant studies....

journal_title：Journal of human hypertension

authors： Zou Z,Xu FY,Wang L,An MM,Zhang H,Shi XY

更新日期：2011-03-01 00:00:00

abstract：:Cardiovascular risk is subject to circadian variation, with peak morning incidence of myocardial infarction and stroke correlating with the early morning blood pressure (BP) surge (EMBPS). Ideally, antihypertensive therapy should maintain control of BP throughout the 24-h dosing cycle. In two sister studies, Prospecti...

journal_title：Journal of human hypertension

authors： Williams B,Lacourcière Y,Schumacher H,Gosse P,Neutel JM

更新日期：2009-09-01 00:00:00

abstract：:An exaggerated blood pressure (BP) response to exercise predicts future cardiovascular risk. The mechanisms underlying exercise-induced hypertension remain unclear, although endothelial dysfunction and elevated arterial stiffness may contribute. Given the association between reductions in nitric oxide (NO) and vascula...

journal_title：Journal of human hypertension

authors： Campbell R,Fisher JP,Sharman JE,McDonnell BJ,Frenneaux MP

更新日期：2011-04-01 00:00:00