Pharmacologic treatment of essential tremor.

abstract：OBJECTIVE:To investigate whether arginine methylation is altered in patients with amyotrophic lateral sclerosis (ALS) and how it affects disease severity, progression, and prognosis. METHODS:We compared the immunoreactivity of protein arginine methyltransferase 1 (PRMT1) and its products, asymmetric dimethylated prote...

journal_title：Neurology

authors： Ikenaka K,Atsuta N,Maeda Y,Hotta Y,Nakamura R,Kawai K,Yokoi D,Hirakawa A,Taniguchi A,Morita M,Mizoguchi K,Mochizuki H,Kimura K,Katsuno M,Sobue G

更新日期：2019-04-16 00:00:00

abstract：OBJECTIVE:To conduct a systematic review on the association between tetanus vaccination and the risk of multiple sclerosis (MS). METHODS:The authors searched the databases Medline, LILACS, EMBASE, and Science Citation Index including the period 1966 to September 1, 2005. Eligible studies had to meet the following incl...

journal_title：Neurology

authors： Hernán MA,Alonso A,Hernández-Díaz S

更新日期：2006-07-25 00:00:00

abstract：:The authors report a patient with chorea and multifocal neurologic abnormalities associated with a small-cell lung carcinoma. A previously unreported antibody directed at a 76-kD neuronal protein antigen was identified in both serum and CSF. Antitumor treatment resulted in dramatic and sustained clinical neurologic an...

journal_title：Neurology

authors： Croteau D,Owainati A,Dalmau J,Rogers LR

更新日期：2001-08-28 00:00:00

abstract：OBJECTIVE:We prospectively investigated the role of depressive symptoms (DS) on all-cause dementia in a population with small vessel disease (SVD), considering onset age of DS and cognitive performance. METHODS:The RUN DMC study (Radboud University Nijmegen Diffusion Tensor and Magnetic Resonance Cohort) is a prospect...

journal_title：Neurology

authors： van Uden IW,van der Holst HM,van Leijsen EM,Tuladhar AM,van Norden AG,de Laat KF,Claassen JA,van Dijk EJ,Kessels RP,Richard E,Tendolkar I,de Leeuw FE

更新日期：2016-09-13 00:00:00

abstract：:Six patients with Parkinson's disease, six patients with essential or intention tremor, and nine controls were tested on a step-tracking task using a joystick control and oscilloscope display. Tremor subjects resembled controls in making an initial ballistic movement followed by (defective) corrections, and took longe...

journal_title：Neurology

authors： Flowers K

更新日期：1975-05-01 00:00:00

abstract：:To explore the clinical heterogeneity associated with the Friedreich's ataxia (FRDA) expanded repeat and provide preliminary guidance for future gene testing in patients suspected of having FRDA, we tested patients with typical FRDA (group I), late-onset FRDA or FRDA with retained reflexes (group II), as well as those...

journal_title：Neurology

authors： Geschwind DH,Perlman S,Grody WW,Telatar M,Montermini L,Pandolfo M,Gatti RA

更新日期：1997-10-01 00:00:00

abstract：OBJECTIVE:To assess if multifocal motor neuropathy (MMN) with and MMN without conduction block (CB) are similar or distinct diseases. METHODS:The authors reviewed the clinical features and responses to IV immunoglobulin (IVIg) treatment of patients with MMN with and without CB at diagnosis, after 4 years of follow-up ...

journal_title：Neurology

authors： Delmont E,Azulay JP,Giorgi R,Attarian S,Verschueren A,Uzenot D,Pouget J

更新日期：2006-08-22 00:00:00

abstract：OBJECTIVE:To examine whether prior statin use affects outcome and intracranial hemorrhage (ICH) rates in stroke patients receiving IV thrombolysis (IVT). METHODS:In a pooled observational study of 11 IVT databases, we compared outcomes between statin users and nonusers. Outcome measures were excellent 3-month outcome ...

journal_title：Neurology

authors： Engelter ST,Soinne L,Ringleb P,Sarikaya H,Bordet R,Berrouschot J,Odier C,Arnold M,Ford GA,Pezzini A,Zini A,Rantanen K,Rocco A,Bonati LH,Kellert L,Strbian D,Stoll A,Meier N,Michel P,Baumgartner RW,Leys D,Tatlisum

更新日期：2011-08-30 00:00:00

abstract：:Factors affecting osmotic fragility were studied in red blood cells of patients with Duchenne muscular dystrophy. The mean osmotic fragility (MOF), operationally defined as the NaCl concentration for 50% hemolysis, was found to be higher by 3.63 +/- 0.51 mM in Duchenne cells than in normal cells having an MOF of 60.1 ...

journal_title：Neurology

authors： Kim HD,Luthra MG,Watts RP,Stern LZ

更新日期：1980-07-01 00:00:00

abstract：:Electrophysiologic studies were carried out on 11 patients with Holmes-Adie syndrome, 8 of whom had reduced or absent ankle jerks. Conduction velocities and evoked nerve and muscle compound action potentials in the peroneal, posterior tibial, and sural nerves were normal. The H reflex was absent (or virtually absent) ...

journal_title：Neurology

authors： Miyasaki JM,Ashby P,Sharpe JA,Fletcher WA

更新日期：1988-02-01 00:00:00

abstract：OBJECTIVE:Using interictal alpha-[11C]methyl-l-tryptophan ([11C]AMT) PET scan, the authors have undertaken a quantitative analysis of all tubers visible on MRI or 2-deoxy-2-[18F]fluoro-d-glucose ([18F]FDG) PET, to determine the relationship between [11C]AMT uptake and epileptic activity on EEG. BACKGROUND:Tuberous scl...

journal_title：Neurology

authors： Asano E,Chugani DC,Muzik O,Shen C,Juhász C,Janisse J,Ager J,Canady A,Shah JR,Shah AK,Watson C,Chugani HT

更新日期：2000-05-23 00:00:00

abstract：OBJECTIVE:To determine the frequency of Lewy bodies (LB) in progressive supranuclear palsy (PSP). BACKGROUND:LB are characteristic of PD, but are also found in normal controls and in other neurodegenerative diseases, especially AD. METHOD:The authors evaluated the brains of 72 consecutive cases of pathologically conf...

journal_title：Neurology

authors： Tsuboi Y,Ahlskog JE,Apaydin H,Parisi JE,Dickson DW

更新日期：2001-11-13 00:00:00

abstract：BACKGROUND:To date, there is no accepted clinical diagnostic test for Parkinson disease (PD) that is based on biochemical analysis of blood or CSF. The discovery of mutations in the SNCA gene encoding α-synuclein in familial parkinsonism and the accumulation of α-synuclein in the PD brain suggested a critical role for ...

journal_title：Neurology

authors： Tokuda T,Qureshi MM,Ardah MT,Varghese S,Shehab SA,Kasai T,Ishigami N,Tamaoka A,Nakagawa M,El-Agnaf OM

更新日期：2010-11-16 00:00:00

abstract：:Educators of the next generation of neurologists will face several challenges, including changes in academic medical centers and hospitals, changes in the scope and practice of neurology itself, and changes in trainees, related to both access to information technology and professional goals. This article, which origin...

journal_title：Neurology

authors： Elkind MS

更新日期：2009-02-17 00:00:00

abstract：OBJECTIVE:To evaluate the integrity of the dorsal striatal dopaminergic innervation in rigid and choreic Huntington disease (HD). BACKGROUND:Some patients with HD have an akinetic-rigid phenotype. It has been suggested that nigrostriatal in addition to striatal pathology is present in this subgroup. The authors sought...

journal_title：Neurology

authors： Bohnen NI,Koeppe RA,Meyer P,Ficaro E,Wernette K,Kilbourn MR,Kuhl DE,Frey KA,Albin RL

更新日期：2000-05-09 00:00:00

abstract：BACKGROUND:The clinical characteristics of Tourette syndrome (TS) present challenges for the systematic determination of whether individuals are affected and severity. Vocal and motor tics wax and wane, decrease over time, and may be voluntarily suppressible, and therefore may be absent at interview. Current instrument...

journal_title：Neurology

authors： Robertson MM,Banerjee S,Kurlan R,Cohen DJ,Leckman JF,McMahon W,Pauls DL,Sandor P,van de Wetering BJ

更新日期：1999-12-10 00:00:00

abstract：:The authors report two cases of patients with word deafness. The word deafness occurred after a head injury for the first patient and after an arterio venous malformation embolization for the second patient. MRI demonstrated bilateral lesions of the inferior colliculi but brainstem auditory-evoked potentials (BAEP) we...

journal_title：Neurology

authors： Vitte E,Tankéré F,Bernat I,Zouaoui A,Lamas G,Soudant J

更新日期：2002-03-26 00:00:00

abstract：:Mutations in NOTCH3 are the cause of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL), a hereditary angiopathy causing stroke and vascular dementia. All CADASIL mutations identified so far result in the loss or gain of one cysteine residue within epidermal growth fac...

journal_title：Neurology

authors： Dichgans M,Herzog J,Gasser T

更新日期：2001-11-13 00:00:00

abstract：:Impairment of object-bound movements of the hand performed under visual guidance ("optic ataxia") was a prominent sign in a patient with bilateral circumscribed infarctions in the posterior watershed territory. The sign was interpreted as resulting from defective integration of panoramic visual information with propri...

journal_title：Neurology

authors： Damasio AR,Benton AL

更新日期：1979-02-01 00:00:00

abstract：:Cabergoline, a new ergoline derivative, is a D2-specific dopaminergic agonist that is more potent and longer-acting than other agonist agents. We conducted a randomized, double-blind study of increasing doses of cabergoline taken once a day. Twenty-five patients with Parkinson's disease taking stable doses of levodopa...

journal_title：Neurology

authors： Hutton JT,Morris JL,Brewer MA

更新日期：1993-03-01 00:00:00

abstract：:Study of diagnostic practice is necessary to optimize neurologists' clinical performance and ensure patient safety. To our knowledge, this report is the first set of systematic observations of diagnostic practices of community neurologists in their clinics. The study consisted of six 2-week periods of in situ observat...

journal_title：Neurology

authors： Dhand A,Engstrom J,Dhaliwal G

更新日期：2013-10-15 00:00:00

abstract：:Ninety-seven chronic alcoholics, both impaired and unimpaired, without clinically evident liver disease, showed significantly more cerebral atrophy on computed tomography than age-matched neurologic controls. Age was the variable most highly correlated with cerebral atrophy measurements, and it accounted for most of t...

journal_title：Neurology

authors： Carlen PL,Wilkinson DA,Wortzman G,Holgate R,Cordingley J,Lee MA,Huszar L,Moddel G,Singh R,Kiraly L,Rankin JG

更新日期：1981-04-01 00:00:00

abstract：:We developed a rating scale for tic disorders that uses only objective criteria and accommodates the variety of tic manifestations. Using short videotaped recordings with the examiner out of the taping room, we measured five tic variables: number of body areas affected, frequency of motor tics and vocalizations, and s...

journal_title：Neurology

authors： Goetz CG,Tanner CM,Wilson RS,Shannon KM

更新日期：1987-09-01 00:00:00

abstract：:Intramedullary cysticercosis of the spinal cord is rare; there have been only 26 previous cases. We describe a patient with low back pain, paraparesis, lumbosacral sensory loss, and signs of meningeal irritation. The clinical diagnosis was spinal cord tumor, but at surgery there was a cysticercus cyst within the lumbo...

journal_title：Neurology

authors： Akiguchi I,Fujiwara T,Matsuyama H,Muranaka H,Kameyama M

更新日期：1979-11-01 00:00:00

abstract：OBJECTIVE:To report the incidence of prion disease in the United States. METHODS:Prion disease decedents were retrospectively identified from the US national multiple cause-of-death data for 2003-2015 and matched with decedents in the National Prion Disease Pathology Surveillance Center (NPDPSC) database through compa...

journal_title：Neurology

authors： Maddox RA,Person MK,Blevins JE,Abrams JY,Appleby BS,Schonberger LB,Belay ED

更新日期：2020-01-14 00:00:00

abstract：OBJECTIVE:We aimed to compare survival in the multiple sclerosis (MS) population with a matched cohort from the general population, and to evaluate the association of comorbidity with survival in both populations. METHODS:Using population-based administrative data, we identified 5,797 persons with MS and 28,807 contro...

journal_title：Neurology

authors： Marrie RA,Elliott L,Marriott J,Cossoy M,Blanchard J,Leung S,Yu N

更新日期：2015-07-21 00:00:00

abstract：:Although not approved by the US Food and Drug Administration for the treatment of status epilepticus (SE), valproic acid (VPA) is an emerging option for this purpose. The authors reviewed 63 patients (30 men) with SE treated with IV VPA (average dose, 31.5 mg/kg). Analysis of demographic, clinical, and treatment infor...

journal_title：Neurology

authors： Limdi NA,Shimpi AV,Faught E,Gomez CR,Burneo JG

更新日期：2005-01-25 00:00:00

abstract：OBJECTIVE:To determine the usefulness of the 14-3-3 test in patients with dementia of various causes. BACKGROUND:Recent reports have suggested that the detection of the 14-3-3 protein in the CSF of patients with Creutzfeldt--Jakob disease is a highly sensitive and specific marker of the disease that might be used as a...

journal_title：Neurology

authors： Burkhard PR,Sanchez JC,Landis T,Hochstrasser DF

更新日期：2001-06-12 00:00:00

abstract：OBJECTIVES:To correlate the two types of early ischemic change on noncontrast CT (NCCT) (parenchymal hypoattenuation [PH] and isolated focal swelling [IFS]) with concurrent assessment of cerebral perfusion and to compare their rates of progression to infarction. METHODS:We assessed cortical regions on NCCT for early i...

journal_title：Neurology

authors： Parsons MW,Pepper EM,Bateman GA,Wang Y,Levi CR

更新日期：2007-03-06 00:00:00

abstract：:A 47-year-old woman had myasthenia gravis with only moderate weakness and a consistently poor response to anticholinesterase medication. She was investigated with routine electrophysiologic studies and single-fiber electromyography. The studies showed a limited effect of anticholinesterase medication. There was a decr...

journal_title：Neurology

authors： Schwartz MS,Stålberg E

更新日期：1975-01-01 00:00:00