Abstract:
:Noninvasive diagnosis of cardiac rejection before the advent of myocyte necrosis is important in clinical management of cardiac transplantation. Mice with abdominal heart transplants were studied to determine whether a dual scintigraphy using antimyosin and anti-major histocompatibility complex (MHC) class II antigen monoclonal antibody (mAb) labeled with different isotopes allows to detect early rejection just before myocyte necrosis. Allografts from BALB/c donors were transplanted into C3H/He recipients. Mice were intravenously injected with 100 microCi each of 123I labeled antimyosin and 111In labeled anti-MHC class II mAbs and were sacrificed for gamma counting from 2 to 9 days after transplantation. Localization of two different isotopes was compared with histological degree of acute rejection. Uptake of 111In labeled anti-MHC class II mAb increased from the fourth day after transplantation, however, that of 123I labeled antimyosin mAb was shown only 9 days after transplantation. Induction of MHC class II antigen develops preceding the development of myocyte necrosis, and this difference in time course can be identified by the dual scintigraphy. Thus, dual scintigraphy using anti-myosin and anti-MHC class II mAbs is potentially useful in staging of cardiac rejection.
journal_name
Acta Cardioljournal_title
Acta cardiologicaauthors
Isobe M,Sekiguchi Msubject
Has Abstractpub_date
1996-01-01 00:00:00pages
515-20issue
6eissn
0001-5385issn
1784-973Xjournal_volume
51pub_type
杂志文章abstract:UNLABELLED:The aim of study was to determine the significance of the best echocardiographic parameters for assessing the severity of mitral regurgitation (MR). METHODS:The study population consisted of 107 patients, mean age 52 +/- 7 y with chronic isolated non-ischaemic MR. Quantification of the MR was performed usin...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.2143/AC.64.2.2036136
更新日期:2009-04-01 00:00:00
abstract:OBJECTIVE:This study sought to examine the use of treatments at discharge in patients hospitalized for myocardial infarction in a French region. METHODS AND RESULTS:Data from 2,102 patients discharged after myocardial infarction were prospectively collected at 48 university, community, and private hospitals in three d...
journal_title:Acta cardiologica
pub_type: 杂志文章,多中心研究
doi:10.2143/AC.56.1.2005589
更新日期:2001-02-01 00:00:00
abstract::The authors present a case of symptomatic non-sustained ventricular tachycardia induced by mechanical irritation of the outflow tract of the right ventricle by a loop in a permanent ventricular pacing lead. Reposition of the lead eliminated the rhythm disturbance. ...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.2143/AC.57.1.2005375
更新日期:2002-02-01 00:00:00
abstract:OBJECTIVE:Red cell distribution width (RDW) is a measure of variation in the volume of circulating erythrocytes and has recently emerged as a powerful prognostic marker in heart failure. We studied the effect of 5-month, home-based cardiac rehabilitation on RDW. METHODS AND RESULTS:Sixty-two patients (age: median 67 y...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.1080/ac.68.6.8000009
更新日期:2013-12-01 00:00:00
abstract:OBJECTIVE:To test the hypothesis that the circulating white blood cell (WBC) and neutrophil counts are related to left ventricular (LV) indices in patients with the same risk area for acute myocardial infarction (AMI), we examined 100 consecutive AMI patients who had the culprit lesion at segment 6 according to the Ame...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.2143/AC.59.5.2005229
更新日期:2004-10-01 00:00:00
abstract::The genesis of the fourth heart sound (S4) is commonly related to the rapid set in vibration of the left ventricular walls, resulting from the rapid inflow of the blood due to the atrial contraction (Nishimura et al., 1989). S4 can be recorded in normal young subjects as an expression of physiologic atrial dynamics bu...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:
更新日期:1995-01-01 00:00:00
abstract::Laser displacement technique is a new method to registrate the low frequency precordial movements. In 16 young healthy men the apexcardiograms were obtained subsequently by conventional way and by laser displacement technique. The basic differences in time intervals and amplitude relations were analyzed with paired t-...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:
更新日期:1990-01-01 00:00:00
abstract:BACKGROUND AND AIM:Decreased left ventricular mass index in anorexia nervosa is amply reported. The aim of this study is to identify non-burdensome predictors of reduced left yentricular mass/height (cLVM) in a cohort of adolescent restrictive anorexic girls. METHODS:This is a retrospective study of all anorexic girls...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.1080/ac.70.4.3094647
更新日期:2015-08-01 00:00:00
abstract::The optimal management of high-risk patients requiring urgent or emergency noncardiac surgery when the options for further testing and evaluation are limited, is unclear. The focus of most of the literature, including the American College of Cardiology/American Heart Association guidelines, has been on patients underg...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.2143/AC.60.5.2004980
更新日期:2005-10-01 00:00:00
abstract:OBJECTIVE:The aim of this paper was to investigate the association between levels of HO-1 expression and angiographic morphology as well as the quantity of coronary lesions in patients with coronary heart disease (CHD). METHODS:110 patients with CHD were diagnosed by coronary angiography which contained coronary lesio...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.2143/AC.61.3.2014831
更新日期:2006-06-01 00:00:00
abstract::Background and aim The purpose of this study was to assess incidence, predictors and outcome of radial artery occlusion (RAO) after transradial catheterization (TRC) based on clinical and Doppler ultrasound study. Methods A total of 1,945 consecutive patients undergoing transradial catheterization for diagnostic evalu...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.1080/00015385.2017.1305158
更新日期:2017-06-01 00:00:00
abstract::Nineteen asymptomatic patients affected by isolated chronic aortic regurgitation received 20 mg of nifedipine sublingually: the acute hemodynamic effects of nifedipine were evaluated by combined cross-sectional and Doppler echocardiography. To assess variations in the regurgitant flow volume, the flow volume across th...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:
更新日期:1993-01-01 00:00:00
abstract::In eighteen consecutive patients (14 male, 4 females, in the age 37-52 years, mean = 43 years) with dilated cardiomyopathy in NYHA functional classification groups III-IV, the efficacy of ambulatory long-term (mean = 6 years) vasodilator therapy by means mechanocardiography (systolic and diastolic time intervals) and ...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:
更新日期:1995-01-01 00:00:00
abstract::Aims: Response to cardiac resynchronisation therapy (CRT) in patients with heart failure depends on the degree of correction of electromechanical dyssynchrony between the left and right ventricles (LV, RV). It is not known whether chronic programming of interventricular (VV) intervals based on characterisation of myoc...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.1080/00015385.2019.1690261
更新日期:2019-11-14 00:00:00
abstract:OBJECTIVE:Coronary stenoses of intermediate severity create difficulties in decision making when revascularization is concerned. Myocardial fractional flow reserve (mFFR), an accurate tool to identify physiological significance of individual coronary stenoses, may help solve this problem. METHODS AND RESULTS:Fifty-eig...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.2143/AC.57.5.2005449
更新日期:2002-10-01 00:00:00
abstract:OBJECTIVE:Cardiac resynchronization therapy (CRT), combined with optimal medical therapy (OMT), is an established treatment for patients with advanced chronic heart failure (ACHF). In ACHF, carvedilol at the dose used in clinical trials, reduces morbidity and mortality. However, patients often do not tolerate the drug ...
journal_title:Acta cardiologica
pub_type: 临床试验,杂志文章
doi:10.1080/ac.66.5.2131081
更新日期:2011-10-01 00:00:00
abstract:OBJECTIVE:This study sought to compare characteristics and management of myocardial infarction in men and women, and whether a difference in management would translate into a difference in in-hospital mortality. METHODS AND RESULTS:Data were prospectively collected in 2,519 patients (801 women) admitted in all hospita...
journal_title:Acta cardiologica
pub_type: 杂志文章,多中心研究
doi:10.2143/AC.56.3.2005637
更新日期:2001-06-01 00:00:00
abstract:INTRODUCTION:There has been a long-standing controversy regarding the mechanism(s) to explain the irregular ventricular response during atrial tachycardia (AT) or atrial fibrillation (AF) and where the site of block, if any, resides in the atrioventricular (AV) junction. METHODS:We studied 12 Langendorff preparations ...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.1080/ac.67.2.2154213
更新日期:2012-04-01 00:00:00
abstract::We report the M-mode and two-dimensional echocardiographic findings in a patient with familial amyloidosis. The diagnosis was made by the clinical picture and histologic evidence of amyloid in peripheral nerve biopsy. Though the patient had no clinical sign of heart failure, extensive involvement of the heart was demo...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:
更新日期:1981-01-01 00:00:00
abstract:OBJECTIVES:The objective of this study is to evaluate the prevalence of HR2 polymorphism among patients with pulmonary embolism (PE) and healthy subjects. BACKGROUND:Polymorphism in the factor V gene named HR2 has been described as a possible risk factor for venous thromboembolism (VTE) development. Contradictive resu...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.2143/AC.70.6.3120184
更新日期:2015-12-01 00:00:00
abstract::Background: Atrial fibrillation (AF) is related to an increased stroke risk. At present, differentiation between patients with paroxysmal AF (pAF) and without is only possible during AF episodes and not during sinus rhythm. If AF could be diagnosed more quickly and reliably, anticoagulation therapy may be administered...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.1080/00015385.2018.1493248
更新日期:2019-08-01 00:00:00
abstract::This is a review of the effects of E on the symptoms of CHF which affect patients' (pts) quality of life and the signs associated with pts' prognosis. The review is based on clinical studies which were included in the New Drug Application for Vasotec (enalapril maleate, MSD) in the United States. There were 3 open-lab...
journal_title:Acta cardiologica
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1991-01-01 00:00:00
abstract:BACKGROUND:The available literature has not been able to demonstrate the exact association between preoperative statin therapy and the reduction in the rates of major adverse cardiac and cerebrovascular events (MACCE). The aim of this study is to explore these unanswered questions. METHODS:A review of patients having ...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.2143/AC.64.2.2036146
更新日期:2009-04-01 00:00:00
abstract:BACKGROUND:Statins are the most widely prescribed class of drugs for coronary artery disease (CAD) patients and yet literature on the prevalence of statin related adverse effects (AEs) and gaps in patient education is quite limited especially in resource-limited settings of developing world. OBJECTIVES:The present stu...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.1080/00015385.2017.1406884
更新日期:2018-08-01 00:00:00
abstract::Left ventricular aneurysms are common in clinical practice. Although their underlying aetiology is generally clear by the clinical context, it can be hard to define the exact cause in some cases. We report a case of a patient in whom cardiac MRI provided important information about the differential diagnosis of a left...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.1080/ac.66.4.2126612
更新日期:2011-08-01 00:00:00
abstract:PURPOSE:With the aim of recommending proper anticoagulation for patients with atrial fibrillation (AF) and diabetes mellitus, we performed the network meta-analysis comparing the non-vitamin K antagonist oral anticoagulants (NOACs) and warfarin in terms of efficacy (stroke or systemic embolism) and safety (major bleedi...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.1080/00015385.2020.1869671
更新日期:2021-01-12 00:00:00
abstract:OBJECTIVE:This study evaluated autonomic nervous system function in 5 young (6-10 years old) and 5 older (10-15 years) children with recurrent episodes of neurally mediated syncope and a positive tilt-test result, 10 with syncope but a negative test result and 30 age-matched healthy volunteers. METHODS:Time- (SDNN, SD...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.2143/AC.55.3.2005734
更新日期:2000-06-01 00:00:00
abstract::Background: Few data are available on long-term atherothrombotic events after percutaneous transluminal angioplasty (PTA) for peripheral arterial disease (PAD). Restenosis after PTA may be a marker of a more aggressive atherothrombosis. Aim: To ascertain whether restenosis detected by duplex sonography (DUS) after PTA...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.1080/00015385.2019.1653565
更新日期:2019-08-15 00:00:00
abstract:OBJECTIVE:Biodegradable polymer drug-eluting stents may improve biocompatibility and reduce the risk of very late stent thrombosis (ST) but outcomes are nevertheless unknown in diabetic patients. The purpose of this study was to assess the long-term efficacy and safety of the biodegradable polymer biolimus A9-eluting s...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.1080/ac.69.5.3044879
更新日期:2014-10-01 00:00:00
abstract::A case of pulmonary valve endocarditis in a patient with patent ductus arteriosus is reported. The diagnosis was made by echocardiographic examination. The M mode echocardiogram showed "shaggy" echoes on the pulmonic valve and the two dimensional echocardiogram disclosed a big vegetation in the right outflow tract. Th...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:
更新日期:1986-01-01 00:00:00