Abstract:
OBJECTIVE:The aim of this paper was to investigate the association between levels of HO-1 expression and angiographic morphology as well as the quantity of coronary lesions in patients with coronary heart disease (CHD). METHODS:110 patients with CHD were diagnosed by coronary angiography which contained coronary lesions in some way. Firstly, the patients were divided into 3 groups according to the angiographic morphology of their coronary lesions: type I (smooth borders) group (n1= 36), type II (irregular borders) group (n2= 48) and type III (long and irregular lesions) group (n3= 26). Secondly, the patients were split into a further 3 groups, named: single-vessel group (SV, 38 cases), double-vessel group (DV, 44 cases) and multi-vessel group (MV, 28 cases) according to the number of coronary lesions. Another 30 patients with normal coronary arteries (diagnosed by coronary angiography) were selected as the control group. The levels of HO-1 protein expression in monocytes and lymphocytes from the subjects were tested by immunohistochemistry and Western blot. A computer picture analysing system was also used to measure the levels of HO-1 protein expression. RESULTS:HO-1 protein was located in cell plasma and the levels of HO-1 protein expression in patients with CHD were significantly higher than in those without CHD (p < 0.01). There were significant differences of HO-1 expression among patients with CHD. Patients with type III lesions had the highest levels, followed by those with type II lesions and the lowest levels were found in patients with type I lesions (p < 0.01). Also, levels of HO-1 protein expression in patients with multi-vessel disease and double-vessel disease were significantly higher than in those with single-vessel disease (p < 0.01). CONCLUSIONS:There is a higher expression of HO-1 in patients with CHD and the levels of HO-1 protein are associated with severity of CHD angiographically.
journal_name
Acta Cardioljournal_title
Acta cardiologicaauthors
Li YG,Wang DM,Chen SM,Tan XR,Fang XY,Wu JW,Zhang GH,Mai RQdoi
10.2143/AC.61.3.2014831subject
Has Abstractpub_date
2006-06-01 00:00:00pages
295-300issue
3eissn
0001-5385issn
1784-973Xjournal_volume
61pub_type
杂志文章abstract::The modifications that atrial flutter determines on the phonocardiogram, apexcardiogram, carotid pulse tracing, jugular venous pulse tracing, and indirect (esophageal) left atrial pulse tracing were studied. On the basis of the data here presented and that of the literature, a polygraphic profile of atrial flutter has...
journal_title:Acta cardiologica
pub_type: 杂志文章
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更新日期:1976-01-01 00:00:00
abstract::A 57-year-old woman suffering from severe Prinzmetal's angina was treated with a 7-week course of enhanced external counterpulsation (EECP). After completing EECP the angina intensity was reduced from CCS class IV to class I, quality of life was increased and medication was significantly reduced. The number of hospita...
journal_title:Acta cardiologica
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doi:10.2143/AC.65.2.2047066
更新日期:2010-04-01 00:00:00
abstract:OBJECTIVE:Biodegradable polymer drug-eluting stents may improve biocompatibility and reduce the risk of very late stent thrombosis (ST) but outcomes are nevertheless unknown in diabetic patients. The purpose of this study was to assess the long-term efficacy and safety of the biodegradable polymer biolimus A9-eluting s...
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doi:10.1080/ac.69.5.3044879
更新日期:2014-10-01 00:00:00
abstract::Background: This study aimed to examine the value of prognostic nutritional index (PNI) as a predictor of outcomes in patients with heart failure and preserved ejection fraction (HFpEF).Methods: We prospectively followed consecutive adult patients admitted to the cardiology outpatient units with HFPEF. Echocardiograph...
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doi:10.1080/00015385.2019.1661139
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abstract:OBJECTIVE:Cigarette smoking increases the synthesis of angiotensin-1 converting enzyme (ACE) and induces oxidative modifications of the apolipoprotein E (apo E).Thus we explored the gene-environment interactions between APOE gene epsilon and ACE gene insertion/deletion polymorphisms and cigarette smoking in coronary ar...
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更新日期:2008-12-01 00:00:00
abstract::Enalapril is a new angiotensin converting enzyme inhibitor which, when absorbed by the digestive tract, is converted to enalaprilat. This metabolite is, in fact, the active form of enalapril. Its duration of action is sufficiently long so that enalapril can be administered in a single daily dose. Enalapril has been pr...
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pub_type: 杂志文章,评审
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abstract::A 22-year-old male who had Mustard repair for complete transposition presented with progressive exercise intolerance, documented by a gradual decrease in exercise capacity on cycle ergometer. Cardiac catheterization and angiography demonstrated subvalvular pulmonary stenosis. After surgical relief of the obstruction, ...
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doi:
更新日期:1993-01-01 00:00:00
abstract::Open surgery for aortic dissection with crevasse in the vicinity of critical branching (CVCB-AD) is frequently associated with several complications and a high mortality rate. We report the management of 53 patients with CVCB-AD who underwent a novel hybrid procedure including both open surgery and endovascular stenti...
journal_title:Acta cardiologica
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doi:10.1080/ac.69.3.3027828
更新日期:2014-06-01 00:00:00
abstract::Residual risk, which cannot be prevented by statins alone, must be controlled for inhibiting the onset of coronary events. Omega-3 polyunsaturated fatty acids (PUFAs) play an important role in controlling residual risk. The Japan eicosapentaenoic acid (EPA) Lipid Intervention Study demonstrated the inhibitory effect o...
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更新日期:2011-04-01 00:00:00
abstract:AIM:We aimed to compare the incidence of contrast-induced nephropathy (CIN) between atorvastatin versus rosuvastatin in patients with ST-segment elevation myocardial infarction (STEMI) undergoing primary coronary angioplasty. METHODS:One hundred ninety-two consecutive patients, who underwent primary percutaneous inter...
journal_title:Acta cardiologica
pub_type: 杂志文章,随机对照试验
doi:10.1080/ac.68.5.2994472
更新日期:2013-10-01 00:00:00
abstract::Purulent pericarditis is rarely the primary site of bacterial infection. It is usually a complication of an infection originating elsewhere in the body, arising by contiguous spread or haematogenous dissemination.This paper, however, describes a previously healthy young man, who developed a purulent streptococcal peri...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.2143/AC.57.5.2005459
更新日期:2002-10-01 00:00:00
abstract::Between April 1988 and October 1989, 22 adult patients with isolated or predominant severe mitral stenosis underwent Percutaneous Transvenous Mitral Valvuloplasty (PTMV). In 20 patients, a transseptal double balloon technique was used; in the last 2 patients, dilatation was performed using the Inoué balloon. Immediate...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:
更新日期:1990-01-01 00:00:00
abstract::Though cardiac involvement is a frequent finding in patients with Duchenne muscular dystrophy (DMD) at the wheel-chair-bound stage, left ventricular hypertrabeculation (LVHT) has not been reported. The patient is a 28-year-old male with the typical clinical features of end stage DMD. Since the age of 16 years he requi...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.2143/AC.60.4.2004996
更新日期:2005-08-01 00:00:00
abstract::Jugular vein thrombosis (JVT) is usually secondary to central venous catheterisation, distant malignancy, hypercoagulable state or ovarian hyperstimulation syndrome. Spontaneous internal JVT is an extremely rare entity. A 61-year-old man presented with swelling of the right side of his face. An ultrasonographic scan s...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.2143/AC.64.5.2042704
更新日期:2009-10-01 00:00:00
abstract::The pharmacokinetic parameters for a two compartment open model were defined for six patients receiving a wide range of Digoxin doses. It was demonstrated that the two compartment model is a valid one to use for Digoxin pharmacokinetics. This model is an useful concept because it can explain the necessity to vary Digo...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:
更新日期:1975-01-01 00:00:00
abstract::Mitral annular calcification is a degenerative process. It is mostly asymptomatic. As the calcification becomes more extensive it might be mistaken for an intracardiac tumour. Mitral annular calcification predicts cardiovascular events, cardiovascular death and overall death. It is predictive of a doubling of the stro...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.1080/ac.69.3.3027838
更新日期:2014-06-01 00:00:00
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journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.2143/AC.63.2.2029518
更新日期:2008-04-01 00:00:00
abstract::A young woman with systemic lupus erythematosus (SLE) developed progressive heart failure several years after mitral valve replacement with a Björk-Shiley prosthesis for treating mitral stenosis due to Libman-Sacks endocarditis. She was admitted to the hospital with pulmonary oedema. Transoesophageal echocardiography ...
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pub_type: 杂志文章,评审
doi:10.2143/AC.55.1.2005719
更新日期:2000-02-01 00:00:00
abstract::Most accessory pathways in pre-excitation syndrome are capable of antegrade conduction from atrium to ventricle, and identified by characteristic ECG abnormalities such as a delta wave (ventricular pre-excitation) and a shortened PR interval.Therefore, the traditional diagnosis method is to detect the initial changes ...
journal_title:Acta cardiologica
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更新日期:2013-04-01 00:00:00
abstract::This is a report on a prospective case-control study, in which a group of patients with an electrocardiographic diagnosis of QTc-prolongation (cases) was compared with a group of patients with a normal QTc (controls) for the presence of potential causative factors. Twelve cases and twelve carefully-matched controls we...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:
更新日期:1993-01-01 00:00:00
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journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.2143/AC.62.2.2020232
更新日期:2007-04-01 00:00:00
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journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.1080/ac.66.5.2131091
更新日期:2011-10-01 00:00:00
abstract::Aim of this study was to elucidate the diagnostic significance of left axis deviation (LAD) in patients (pts) with chronic (> 6 months) left bundle branch block (LBBB). We retrospectively studied 2094 consecutive pts who underwent cardiac catheterization. All pts had left heart catheterization and coronary angiography...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:
更新日期:1997-01-01 00:00:00
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journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.1080/ac.67.3.2160731
更新日期:2012-06-01 00:00:00
abstract::We report the case of a 61-year-old male patient who suffered a spontaneous (atraumatic) splenic rupture (SSR) following splenic infarction treated by heparin anticoagulation. Splenic rupture precipitated by thrombolytic or anticoagulant therapy has been reported and putatively attributed to unrecognized micro-traumat...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.1080/ac.68.4.2988897
更新日期:2013-08-01 00:00:00
abstract:BACKGROUND:Available clinical and angiographic scoring systems fail to predict clinical outcomes in real-world patients undergoing revascularization of the unprotected left main coronary artery (ULMCA). METHODS:We prospectively assessed major adverse cardiac and cerebrovascular events (MACCE) in a real-world populatio...
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pub_type: 杂志文章,多中心研究
doi:10.1080/ac.67.5.2174124
更新日期:2012-10-01 00:00:00
abstract::A 69-year-old woman was evaluated for chest pain complaints. The ECG demonstrated sinus rhythm with deep negative T waves from V2 to V6, in l, aVL and the inferior leads.Transthoracic echocardiography (TTE) showed suboptimal image quality and was nondiagnostic. A repeat TTE study after administration of an echo contra...
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pub_type: 杂志文章
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更新日期:2012-08-01 00:00:00
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pub_type: 杂志文章
doi:10.1080/ac.68.1.2959632
更新日期:2013-02-01 00:00:00
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journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.1080/00015385.2017.1281539
更新日期:2017-02-01 00:00:00