Rosuvastatin versus atorvastatin to prevent contrast induced nephropathy in patients undergoing primary percutaneous coronary intervention (ROSA-cIN trial).

Abstract:

AIM:We aimed to compare the incidence of contrast-induced nephropathy (CIN) between atorvastatin versus rosuvastatin in patients with ST-segment elevation myocardial infarction (STEMI) undergoing primary coronary angioplasty. METHODS:One hundred ninety-two consecutive patients, who underwent primary percutaneous intervention (p-PCI) with the diagnosis of STEMI, were included in the study. The patients were randomized to take atorvastatin 80 mg (n=98) or rosuvastatin 40 mg (n= 94) before the procedure. Biochemical and complete blood count measurements were done at baseline and at 48 hours following admission. RESULTS:The incidence of CIN was 8.9% (n= 17) in the entire groups. The analysis performed between the statin groups revealed no statistical difference in any of the renal dysfunction indicators [baseline creatinine, baseline estimated glomerular filtration rate (eGFR), creatinine at 48 h, eGFR at 48 h, difference between baseline and 48 h creatinine, the per cent increase in the creatinine at 48 hours relative to basal creatinine]. In STEMI patients undergoing primary PCI, only the amount of the contrast agent administered was determined to be an independent predictor for CIN (OR and 95% CI: 1.08 (1.03- 1.13), P< or = 0.001). Left ventricular ejection fraction exhibited borderline statistical significance (OR and 95% CI: 0.88 (0.77-1.01), P= 0.07). CONCLUSION:Atorvastatin and rosuvastatin had similar efficacy in preventing CIN in patients with STEMI undergoing P-PCI.

journal_name

Acta Cardiol

journal_title

Acta cardiologica

authors

Kaya A,Kurt M,Tanboğa IH,Işik T,Ekinci M,Aksakal E,Kaya Y,Topçu S,Sevimli S

doi

10.1080/ac.68.5.2994472

subject

Has Abstract

pub_date

2013-10-01 00:00:00

pages

489-94

issue

5

eissn

0001-5385

issn

1784-973X

journal_volume

68

pub_type

杂志文章,随机对照试验
  • Aberrant right coronary artery arising from the left sinus of Valsalva with an interarterial course.

    abstract::An anomalous origin of the right coronary artery from the left sinus of Valsalva with an interarterial course is a rather rare congenital anomaly. Treatment strategies are determined by the risk of sudden cardiac death and the presence of cardiac ischaemia. We present two cases of middle-aged patients who were diagnos...

    journal_title:Acta cardiologica

    pub_type: 杂志文章

    doi:10.1080/ac.69.2.3017300

    authors: De Pooter J,Van Driessche L,Bartunek J

    更新日期:2014-04-01 00:00:00

  • Acute pericarditis induced stress cardiomyopathy.

    abstract::A 67-year-old Caucasian woman presented with chest pain suggestive of acute pericarditis. On initial evaluation the apical ballooning variant of stress-related cardiomyopathy (CMP) was present. The stress CMP and acute pericarditis resolved within a week. The patient returned in four weeks with early cardiac tamponade...

    journal_title:Acta cardiologica

    pub_type: 杂志文章

    doi:10.2143/AC.65.3.2050358

    authors: Li JW,Nanda S,Longo S

    更新日期:2010-06-01 00:00:00

  • Compartments and suborgans of the ventricular myocardium.

    abstract::Color-coded liquid plastic was injected intraparenchymally (not into the blood vessels) into more than 300 hearts of homeotherms--including dog, cat, sheep, beef, horse, mammalian dolphins, chickens, turkeys, etc. The organization of the hearts of all these species appears to be similar. After injection of a heart seg...

    journal_title:Acta cardiologica

    pub_type: 杂志文章

    doi:

    authors: Rodbard S

    更新日期:1976-01-01 00:00:00

  • The predictive value of QRS duration in response to levosimendan therapy in patients with decompensated heart failure.

    abstract:PURPOSE:We aimed to investigate the role of QRS duration on the surface electrocardiogram (ECG) in predicting response to levosimendan therapy in patients with acute systolic heart failure. METHODS:Patients with an ejection fraction (EF) lower than 35% who required intravenous inotropic support despite optimal heart f...

    journal_title:Acta cardiologica

    pub_type: 杂志文章

    doi:10.1080/ac.67.3.2160721

    authors: Cetin M,Uçar O,Cicekçioğlu H,Güven Cetin Z,Sahin M,Vasfi Ulusoy F,Aydoğdu S

    更新日期:2012-06-01 00:00:00

  • Angiotensin-converting enzyme polymorphism in healthy young subjects: relationship to left ventricular mass and functions.

    abstract:OBJECTIVES:Angiotensin-converting enzyme (ACE) is a key enzyme in the production of angiotensin II and thus may participate in the modulation of cardiac growth. The cloning of the ACE gene has made it possible to identify a deletion (D)-insertion (I) polymorphism that appears to affect the level of serum ACE activity. ...

    journal_title:Acta cardiologica

    pub_type: 杂志文章

    doi:10.2143/AC.60.2.2005025

    authors: Dursunoglu D,Evrengül H,Tanriverdi H,Turgut G,Genç O,Kaftan HA,Kilic M

    更新日期:2005-04-01 00:00:00

  • Acute ST-segment elevation in Neisseria meningitis.

    abstract::Meningitis due to Neisseria meningitidis occurred in a young man. On admission, he was in septic shock and the electrocardiogram revealed convex upwards ST-segment elevation in inferior and lateral leads. Rapid and complete normalisation of the ECG was observed and the patient had a favourable evolution with intensive...

    journal_title:Acta cardiologica

    pub_type: 杂志文章

    doi:10.2143/AC.56.5.2005695

    authors: Gach O,Lancellotti P,Pierard LA

    更新日期:2001-10-01 00:00:00

  • Effect of dobutamine stress echocardiography on serum heart fatty acid binding protein levels.

    abstract::Objective Heart fatty acid binding protein (HFABP) is a low-molecular-weight free protein that is abundant in the intracytoplasmic space of myocytes. Due to its unique features, serum HFABP levels may increase in myocardial ischaemia. The aim of this study was to evaluate the effect of myocardial ischaemia induced by ...

    journal_title:Acta cardiologica

    pub_type: 杂志文章

    doi:10.1080/00015385.2017.1291181

    authors: Akinci S,Balcioğlu AS,Taçoy G,Tavil Y,Gülbahar Ö,Özdemir M

    更新日期:2017-04-01 00:00:00

  • Chest pain after partial upper versus complete sternotomy for aortic valve surgery.

    abstract:OBJECTIVE:The aim of this study was to evaluate pain and pulmonary function after partial upper versus complete sternotomy for aortic valve surgery. METHODS AND RESULTS:In a prospective study of 31 adult patients, 15 individuals underwent aortic valve replacement via partial upper sternotomy, and 16 patients were oper...

    journal_title:Acta cardiologica

    pub_type: 杂志文章

    doi:10.2143/AC.58.1.2005254

    authors: Candaele S,Herijgers P,Demeyere R,Flameng W,Evers G

    更新日期:2003-02-01 00:00:00

  • Clinical and coronary angiographic characteristics of patients with coronary slow flow.

    abstract:BACKGROUND:The coronary slow flow phenomenon is an angiographic finding characterized by delayed distal vessel opacification in the absence of significant epicardial coronary disease, and is an important clinical entity because it may be the cause of angina at rest or during exercise, acute myocardial infarction, and h...

    journal_title:Acta cardiologica

    pub_type: 杂志文章

    doi:10.2143/AC.63.5.2033224

    authors: Yilmaz H,Demir I,Uyar Z

    更新日期:2008-10-01 00:00:00

  • Predictive accuracy of CHA2DS2-VASc score in determining the high thrombus burden in patients with non-ST-elevation myocardial infarction.

    abstract::Background: The presence of intracoronary thrombus is associated with increased ischaemic complications in patients with NSTEMI. High thrombus burden is an independent predictor of major adverse cardiovascular events, stent thrombosis and no reflow in patients with STEMI. CHA2DS2-VASc score predicts thrombus burden in...

    journal_title:Acta cardiologica

    pub_type: 杂志文章

    doi:10.1080/00015385.2019.1707934

    authors: Satılmış S,Durmuş G

    更新日期:2020-01-03 00:00:00

  • Influence of percutaneous transcatheter closure of an atrial septal defect on the atrioventricular conduction.

    abstract:OBJECTIVE:This study aimed at determining the effect of percutaneous ASD closure on the AV conduction. Percutaneous closure of ostium secundum atrial septal defects (ASDs) has been widely accepted and has become the standard treatment of this malformation. However, some complications have been reported. Because of the ...

    journal_title:Acta cardiologica

    pub_type: 杂志文章

    doi:10.1080/ac.66.3.2114130

    authors: Cottens D,Van De Bruaene A,Troost E,Willems R,Moons P,Budts W

    更新日期:2011-06-01 00:00:00

  • Impact of defibrillation threshold testing on burden of heart failure hospitalizations.

    abstract::Background: Defibrillation threshold testing (DT) following implantable cardioverter defibrillator (ICD) implantation has not shown to improve mortality. However, the impact of DT on burden of heart failure (HF) hospitalisations has not been well defined.Methods: We studied retrospectively consecutive patients who und...

    journal_title:Acta cardiologica

    pub_type: 杂志文章

    doi:10.1080/00015385.2019.1630586

    authors: Akdemir B,Li Y,Krishnan B,Adabag S,Tholakanahalli V,Benditt DG,Li JM

    更新日期:2020-06-01 00:00:00

  • Stroke and recurrent peripheral embolism in left atrial myxoma.

    abstract::Primary cardiac tumours are uncommon, with an estimated incidence between 0.0017% and 0.19%. Cardiac myxoma is a rare cause of cerebrovascular disease, especially in children. This case report emphasizes the importance of cardiac evaluation, especially echocardiographic examination in cases with stroke and peripheral ...

    journal_title:Acta cardiologica

    pub_type: 杂志文章

    doi:10.2143/AC.65.1.2045899

    authors: Uner A,Dogan M,Sal E,Peker E

    更新日期:2010-02-01 00:00:00

  • Haemodynamic alterations of the left ventricle during right atrial pacing.

    abstract::The left ventricular haemodynamic alterations during right atrial pacing were studied in 12 cases. Cardiac index varied little: during maximal rate however, its mean value was slightly lower than the resting one. Stroke index decreased inversely to the heart rate. The course of these indices did not separate the norma...

    journal_title:Acta cardiologica

    pub_type: 杂志文章

    doi:

    authors: Kolettis M,Gialafos J,Toutouzas P,Avgoustakis D

    更新日期:1976-01-01 00:00:00

  • Oxidized LDL and coronary heart disease.

    abstract::During inflammation, several cell types synthesize and secrete phospholipase A2 that catalyses lipid oxidation in LDL. Myeloperoxidase, a haeme protein secreted by activated phagocytes, oxidizes L-tyrosine to a tyrosyl radical that is a physiological catalyst for the initiation of lipid oxidation in LDL. Lipid oxidati...

    journal_title:Acta cardiologica

    pub_type: 杂志文章,评审

    doi:10.2143/AC.59.5.2005219

    authors: Holvoet P

    更新日期:2004-10-01 00:00:00

  • New index of cardiac contractility during stress testing with treadmill.

    abstract::Experimental demonstration that the external phonocardiogram is similar to the third derivative (rate of acceleration) of LV pressure, and that catecholamines cause a similar increase of the early systolic wave of the first derivative of LV pressure and of S1 prompted a study of the first sound during stress testing. ...

    journal_title:Acta cardiologica

    pub_type: 杂志文章

    doi:

    authors: Luisada A,Singhal A,Knighten V

    更新日期:1986-01-01 00:00:00

  • Endothelial dysfunction in hypertension.

    abstract::Endothelial cells release both relaxing and contracting factors that modulate vascular smooth muscle tone and also participate in the pathophysiology of essential hypertension. Endothelium-dependent vasodilation is regulated primarily by nitric oxide but also by an unidentified endothelium-derived hyperpolarizing fact...

    journal_title:Acta cardiologica

    pub_type: 杂志文章,评审

    doi:10.2143/AC.55.4.2005744

    authors: Puddu P,Puddu GM,Zaca F,Muscari A

    更新日期:2000-08-01 00:00:00

  • Effect of beta-sympatholytic agents on vascular responses to noradrenaline and potassium chloride.

    abstract::Vasoconstrictory responses to noradrenaline (NA) or high potassium chloride (130 mM) usually show a biphasic behaviour: an initial peak is followed by a lower steady state level. The influence of three beta-sympatholytic agents (propranolol, pindolol, practolol) and a "Ca-antagonist" (verapamil) on this particular beh...

    journal_title:Acta cardiologica

    pub_type: 杂志文章

    doi:

    authors: Kababgi MD,Henrich H,Schneider KW

    更新日期:1978-01-01 00:00:00

  • Pilot project for registering acute myocardial infarctions in Belgium.

    abstract::In order to prepare Belgian participation in the International Study "Monitoring of trends and determinants in cardiovascular disease (MONICA)", a pilot project for registration of acute myocardial infarctions was organized in the Flemish city of Ghent and the Walloon city of Charleroi. Thanks to the collaboration of ...

    journal_title:Acta cardiologica

    pub_type: 杂志文章

    doi:

    authors: Berghmans L,Heyerick P,De Backer G,Kornitzer M,Fux M

    更新日期:1985-01-01 00:00:00

  • [Perforation of the interventricular septum, a complication of myocardial infarct].

    abstract::The authors report nine surgical attempts in ventricular septal rupture following myocardial infarction and compare their experience with data from the literature. Two of the three long-term successes have been obtained by the association of infarcectomy and myocardial revascularisation to the repair of the septal rup...

    journal_title:Acta cardiologica

    pub_type: 杂志文章

    doi:

    authors: De Roy L,Col J,Cosyns J,Rousseau M,Ponlot R,Kremer R

    更新日期:1975-01-01 00:00:00

  • Evaluation of the effect of L-thyroxin therapy on cardiac functions by using novel tissue Doppler-derived indices in patients with subclinical hypothyroidism.

    abstract:OBJECTIVES:Subclinical hypothyroidism (SH) is characterized by normal serum free T4 (fT4), free T3 (fT3) levels and increased serum thyroid stimulating hormone (TSH) levels.The aim of this study was to assess the validity of tissue Doppler imaging (TDI) in evaluating cardiac effects of SH and to demonstrate the improvi...

    journal_title:Acta cardiologica

    pub_type: 杂志文章

    doi:10.1080/ac.66.1.2064966

    authors: Oner FA,Yurdakul S,Oner E,Uzum AK,Erguney M

    更新日期:2011-02-01 00:00:00

  • Acute effects of external and internal pacing on ejection fraction in patients with severe cardiac failure.

    abstract::The present study aims at evaluating the acute hemodynamic effects of external and internal (3 and 15 mA) pacing on 30 patients with severe cardiac failure. The global and regional ejection fraction were calculated by repeated radionuclide ventriculography at rest (control) and during increasing pacing rates. Blood pr...

    journal_title:Acta cardiologica

    pub_type: 杂志文章

    doi:

    authors: Toumanidis ST,Danopoulos A,Vassilopoulos N,Nanas SN,Kostamis P,Sideris DA,Moulopoulos SD

    更新日期:1994-01-01 00:00:00

  • Non-invasive evaluation of the haemodynamic effects of amiodarone.

    abstract::Sixteen patients were examined hemodynamically with echocardiography, calibrated apexcardiography, and systolic time intervals before treatment, after 1 week treatment with amiodarone 600 mg daily and after 2-4 months treatment with 300 mg daily. During the treatment thyroid function was controlled. The echocardiogram...

    journal_title:Acta cardiologica

    pub_type: 杂志文章

    doi:

    authors: Buch J,Andersen ED

    更新日期:1984-01-01 00:00:00

  • Chest pain with less than 20% change in high sensitivity troponin T - a low risk cohort?

    abstract::Background: Patients with chest pain are risk-stratified using serial high-sensitivity troponin (T) assays (hsTnT). Those with change in (Δ)hsTnT <20% are often categorised as low-risk and are less likely to be managed as acute coronary syndromes (ACS). We sought to characterise such a population of 'low-risk' chest p...

    journal_title:Acta cardiologica

    pub_type: 杂志文章

    doi:10.1080/00015385.2018.1561598

    authors: Weir RAP,Osmanska J,Docherty KF,Petrie CJ

    更新日期:2020-04-01 00:00:00

  • Effects of exercise to exhaustion in rat myocardium. A stereological study.

    abstract::Stereological methods under light and electron microscopy have been used to study the ventricular myocardium of rats exhausted by swimming exercise. The proportion of myocardial cell/interstitium diminishes with the exercise. This result is interpreted as a consequence of an intercellular edema which becomes more pron...

    journal_title:Acta cardiologica

    pub_type: 杂志文章

    doi:

    authors: Lucena MC,Paniagua R

    更新日期:1984-01-01 00:00:00

  • Echocardiographic aspects of cardiac amyloidosis.

    abstract::We report the M-mode and two-dimensional echocardiographic findings in a patient with familial amyloidosis. The diagnosis was made by the clinical picture and histologic evidence of amyloid in peripheral nerve biopsy. Though the patient had no clinical sign of heart failure, extensive involvement of the heart was demo...

    journal_title:Acta cardiologica

    pub_type: 杂志文章

    doi:

    authors: Piérard L,Verheugt FW,Meltzer RS,Roelandt J

    更新日期:1981-01-01 00:00:00

  • The STIB score: a simple clinical test to predict clopidogrel resistance.

    abstract:BACKGROUND:High platelet reactivity (HPR) to clopidogrel is associated with an increased risk of ischaemic complications during and after coronary interventions and concerns up to 50% of patients undergoing PCI. AIM OF THE STUDY:The aim of the study was to identify patients with HPR to clopidogrel using bedside clinic...

    journal_title:Acta cardiologica

    pub_type: 临床试验,杂志文章,多中心研究

    doi:10.2143/AC.70.5.3110511

    authors: Legrand D,Barbato E,Chenu P,Magne J,Vrolix M,Wijns W,Legrand V,STIB investigators.

    更新日期:2015-10-01 00:00:00

  • Haem oxygenase-1 expression and coronary heart disease--association between levels of haem oxygenase-1 expression and angiographic morphology as well as the quantity of coronary lesions.

    abstract:OBJECTIVE:The aim of this paper was to investigate the association between levels of HO-1 expression and angiographic morphology as well as the quantity of coronary lesions in patients with coronary heart disease (CHD). METHODS:110 patients with CHD were diagnosed by coronary angiography which contained coronary lesio...

    journal_title:Acta cardiologica

    pub_type: 杂志文章

    doi:10.2143/AC.61.3.2014831

    authors: Li YG,Wang DM,Chen SM,Tan XR,Fang XY,Wu JW,Zhang GH,Mai RQ

    更新日期:2006-06-01 00:00:00

  • The thrombus laden coronary artery--forget the fancy stuff, just aspirate it!

    abstract::"No-reflow" is an important complication of percutaneous coronary intervention (PCI) in the setting of acute myocardial infarction and is associated with worse outcomes. Visible thrombus on the angiogram is a significant risk factor for "no-reflow". A variety of strategies have been employed to prevent this phenomenon...

    journal_title:Acta cardiologica

    pub_type: 杂志文章

    doi:10.2143/AC.60.6.2004941

    authors: Jafary FH,Najaf SM

    更新日期:2005-12-01 00:00:00

  • Risk factors for heart failure in adult Nigerians.

    abstract:OBJECTIVES:Heart failure (HF) is a lethal disorder most common in blacks. Available treatment options have little impact on prognosis, making primary prevention a priority. We aimed to describe the spectrum of established HF risk factors and clinical features in Nigerian adults. METHODS:We recruited consecutive adults...

    journal_title:Acta cardiologica

    pub_type: 杂志文章

    doi:10.2143/AC.63.4.2033041

    authors: Laabes EP,Thacher TD,Okeahialam BN

    更新日期:2008-08-01 00:00:00