Abstract:
AIM:We aimed to compare the incidence of contrast-induced nephropathy (CIN) between atorvastatin versus rosuvastatin in patients with ST-segment elevation myocardial infarction (STEMI) undergoing primary coronary angioplasty. METHODS:One hundred ninety-two consecutive patients, who underwent primary percutaneous intervention (p-PCI) with the diagnosis of STEMI, were included in the study. The patients were randomized to take atorvastatin 80 mg (n=98) or rosuvastatin 40 mg (n= 94) before the procedure. Biochemical and complete blood count measurements were done at baseline and at 48 hours following admission. RESULTS:The incidence of CIN was 8.9% (n= 17) in the entire groups. The analysis performed between the statin groups revealed no statistical difference in any of the renal dysfunction indicators [baseline creatinine, baseline estimated glomerular filtration rate (eGFR), creatinine at 48 h, eGFR at 48 h, difference between baseline and 48 h creatinine, the per cent increase in the creatinine at 48 hours relative to basal creatinine]. In STEMI patients undergoing primary PCI, only the amount of the contrast agent administered was determined to be an independent predictor for CIN (OR and 95% CI: 1.08 (1.03- 1.13), P< or = 0.001). Left ventricular ejection fraction exhibited borderline statistical significance (OR and 95% CI: 0.88 (0.77-1.01), P= 0.07). CONCLUSION:Atorvastatin and rosuvastatin had similar efficacy in preventing CIN in patients with STEMI undergoing P-PCI.
journal_name
Acta Cardioljournal_title
Acta cardiologicaauthors
Kaya A,Kurt M,Tanboğa IH,Işik T,Ekinci M,Aksakal E,Kaya Y,Topçu S,Sevimli Sdoi
10.1080/ac.68.5.2994472subject
Has Abstractpub_date
2013-10-01 00:00:00pages
489-94issue
5eissn
0001-5385issn
1784-973Xjournal_volume
68pub_type
杂志文章,随机对照试验abstract::An anomalous origin of the right coronary artery from the left sinus of Valsalva with an interarterial course is a rather rare congenital anomaly. Treatment strategies are determined by the risk of sudden cardiac death and the presence of cardiac ischaemia. We present two cases of middle-aged patients who were diagnos...
journal_title:Acta cardiologica
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abstract::Color-coded liquid plastic was injected intraparenchymally (not into the blood vessels) into more than 300 hearts of homeotherms--including dog, cat, sheep, beef, horse, mammalian dolphins, chickens, turkeys, etc. The organization of the hearts of all these species appears to be similar. After injection of a heart seg...
journal_title:Acta cardiologica
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abstract::Meningitis due to Neisseria meningitidis occurred in a young man. On admission, he was in septic shock and the electrocardiogram revealed convex upwards ST-segment elevation in inferior and lateral leads. Rapid and complete normalisation of the ECG was observed and the patient had a favourable evolution with intensive...
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abstract::Background: Defibrillation threshold testing (DT) following implantable cardioverter defibrillator (ICD) implantation has not shown to improve mortality. However, the impact of DT on burden of heart failure (HF) hospitalisations has not been well defined.Methods: We studied retrospectively consecutive patients who und...
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abstract::The left ventricular haemodynamic alterations during right atrial pacing were studied in 12 cases. Cardiac index varied little: during maximal rate however, its mean value was slightly lower than the resting one. Stroke index decreased inversely to the heart rate. The course of these indices did not separate the norma...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:
更新日期:1976-01-01 00:00:00
abstract::During inflammation, several cell types synthesize and secrete phospholipase A2 that catalyses lipid oxidation in LDL. Myeloperoxidase, a haeme protein secreted by activated phagocytes, oxidizes L-tyrosine to a tyrosyl radical that is a physiological catalyst for the initiation of lipid oxidation in LDL. Lipid oxidati...
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journal_title:Acta cardiologica
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journal_title:Acta cardiologica
pub_type: 杂志文章,评审
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journal_title:Acta cardiologica
pub_type: 杂志文章
doi:
更新日期:1978-01-01 00:00:00
abstract::In order to prepare Belgian participation in the International Study "Monitoring of trends and determinants in cardiovascular disease (MONICA)", a pilot project for registration of acute myocardial infarctions was organized in the Flemish city of Ghent and the Walloon city of Charleroi. Thanks to the collaboration of ...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:
更新日期:1985-01-01 00:00:00
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更新日期:1975-01-01 00:00:00
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doi:
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journal_title:Acta cardiologica
pub_type: 杂志文章
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更新日期:1984-01-01 00:00:00
abstract::Background: Patients with chest pain are risk-stratified using serial high-sensitivity troponin (T) assays (hsTnT). Those with change in (Δ)hsTnT <20% are often categorised as low-risk and are less likely to be managed as acute coronary syndromes (ACS). We sought to characterise such a population of 'low-risk' chest p...
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journal_title:Acta cardiologica
pub_type: 杂志文章
doi:
更新日期:1984-01-01 00:00:00
abstract::We report the M-mode and two-dimensional echocardiographic findings in a patient with familial amyloidosis. The diagnosis was made by the clinical picture and histologic evidence of amyloid in peripheral nerve biopsy. Though the patient had no clinical sign of heart failure, extensive involvement of the heart was demo...
journal_title:Acta cardiologica
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更新日期:1981-01-01 00:00:00
abstract:BACKGROUND:High platelet reactivity (HPR) to clopidogrel is associated with an increased risk of ischaemic complications during and after coronary interventions and concerns up to 50% of patients undergoing PCI. AIM OF THE STUDY:The aim of the study was to identify patients with HPR to clopidogrel using bedside clinic...
journal_title:Acta cardiologica
pub_type: 临床试验,杂志文章,多中心研究
doi:10.2143/AC.70.5.3110511
更新日期:2015-10-01 00:00:00
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journal_title:Acta cardiologica
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更新日期:2006-06-01 00:00:00
abstract::"No-reflow" is an important complication of percutaneous coronary intervention (PCI) in the setting of acute myocardial infarction and is associated with worse outcomes. Visible thrombus on the angiogram is a significant risk factor for "no-reflow". A variety of strategies have been employed to prevent this phenomenon...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.2143/AC.60.6.2004941
更新日期:2005-12-01 00:00:00
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更新日期:2008-08-01 00:00:00