Abstract：
:Background: Defibrillation threshold testing (DT) following implantable cardioverter defibrillator (ICD) implantation has not shown to improve mortality. However, the impact of DT on burden of heart failure (HF) hospitalisations has not been well defined.Methods: We studied retrospectively consecutive patients who underwent ICD implantation or generator change between 2008 and 2014. Primary outcome was burden of HF hospitalisations within 30 days following implantation. Secondary outcomes were mortality, stroke, and ICD shock within 30 days and one-year mortality.Results: Three hundred and eleven of 501 patients (62%) were in DT+ group versus 190 (38%) were in DT- group. The percentage of new implantations was higher in DT+ group than in DT- group (69% vs 39%, p < .001) but the distributions of NYHA function classes were similar between two groups. The burden of HF hospitalisations at 30-days was significantly higher in DT+ group than in DT- group (17.4% vs 4.7%, HR 0.842, 95% CI 0.774-0.915, p < .0001). No difference in mortality, stroke or ICD shocks was found between two groups at 30 days and mortality at 1 year.Conclusions: DT after new ICD or generator replacement was associated with increased HF hospitalisation rates at 30 days after ICD implant in a non-trial HF population. However, there was no association between DT and mortality, stroke and ICD shocks at 30 days or mortality at 1 year. The increased burden of HF hospitalisation in this observational study requires validation by randomised studies.
journal_name
Acta Cardioljournal_title
Acta cardiologicaauthors
Akdemir B,Li Y,Krishnan B,Adabag S,Tholakanahalli V,Benditt DG,Li JMdoi
10.1080/00015385.2019.1630586subject
Has Abstractpub_date
2020-06-01 00:00:00pages
226-232issue
3eissn
0001-5385issn
1784-973Xjournal_volume
75pub_type
杂志文章abstract：:Sixteen patients were examined hemodynamically with echocardiography, calibrated apexcardiography, and systolic time intervals before treatment, after 1 week treatment with amiodarone 600 mg daily and after 2-4 months treatment with 300 mg daily. During the treatment thyroid function was controlled. The echocardiogram...
journal_title：Acta cardiologica
pub_type： 杂志文章
doi：
更新日期：1984-01-01 00:00:00
abstract：OBJECTIVE:The present study aimed to compare the effectiveness and safety of the potential- and the anatomic-guided approach for slow pathway ablation in patients with recurrent episodes of symptomatic common type atrioventricular (AV) nodal reentrant tachycardia. METHODS:Two hundred and twenty-eight patients were ran...
journal_title：Acta cardiologica
pub_type： 杂志文章,随机对照试验
doi：10.2143/AC.64.4.2041612
更新日期：2009-08-01 00:00:00
abstract：OBJECTIVE:This study was performed to assess whether post-stress and rest functional parameters, as measured by gated-SPECT, provide additional predictive value for long-term prognosis, over clinical and perfusion data in patients (pts.) with low left ventricular ejection fraction (LVEF). METHODS:647 consecutive pts. ...
journal_title：Acta cardiologica
pub_type： 临床试验,杂志文章
doi：10.2143/AC.59.1.2005154
更新日期：2004-02-01 00:00:00
abstract：:Objective Heart fatty acid binding protein (HFABP) is a low-molecular-weight free protein that is abundant in the intracytoplasmic space of myocytes. Due to its unique features, serum HFABP levels may increase in myocardial ischaemia. The aim of this study was to evaluate the effect of myocardial ischaemia induced by ...
journal_title：Acta cardiologica
pub_type： 杂志文章
doi：10.1080/00015385.2017.1291181
更新日期：2017-04-01 00:00:00
abstract：:Noninvasive diagnosis of cardiac rejection before the advent of myocyte necrosis is important in clinical management of cardiac transplantation. Mice with abdominal heart transplants were studied to determine whether a dual scintigraphy using antimyosin and anti-major histocompatibility complex (MHC) class II antigen ...
journal_title：Acta cardiologica
pub_type： 杂志文章
doi：
更新日期：1996-01-01 00:00:00
abstract：BACKGROUND:The interest in transcatheter ventricular septal defect (VSD) closure is continuously growing. Therefore, we report our experience in perimembranous (Pm) and postinfarction (Pi) VSD closure. METHODS:All patients, older than 16 years, were selected from a data base, in which Pm and Pi VSDs were registered. T...
journal_title：Acta cardiologica
pub_type： 杂志文章
doi：10.2143/AC.62.4.2022283
更新日期：2007-08-01 00:00:00
abstract：:The pharmacokinetic parameters for a two compartment open model were defined for six patients receiving a wide range of Digoxin doses. It was demonstrated that the two compartment model is a valid one to use for Digoxin pharmacokinetics. This model is an useful concept because it can explain the necessity to vary Digo...
journal_title：Acta cardiologica
pub_type： 杂志文章
doi：
更新日期：1975-01-01 00:00:00
abstract：:The Cardiology Foundation supported by the perspicacious Princess Lilian was created in 1958. As an introduction to this symposium, the challenges that the cardiologist and surgeon encountered in 1958, are recalled as well as the essential problems requiring solutions in that era of evolving cardiac surgery. ...
journal_title：Acta cardiologica
pub_type： 历史文章,杂志文章
doi：
更新日期：2004-01-01 00:00:00
abstract：OBJECTIVE:This study sought to compare characteristics and management of myocardial infarction in men and women, and whether a difference in management would translate into a difference in in-hospital mortality. METHODS AND RESULTS:Data were prospectively collected in 2,519 patients (801 women) admitted in all hospita...
journal_title：Acta cardiologica
pub_type： 杂志文章,多中心研究
doi：10.2143/AC.56.3.2005637
更新日期：2001-06-01 00:00:00
abstract：:Indices of the first derivative and of the normalized first derivative of the left apexcardiogram were used to evaluate the contractile state of the left ventricle of cyclists in the competitive season compared to their resting season and of cardiac patients before and after a physical training program. In both groups...
journal_title：Acta cardiologica
pub_type： 杂志文章
doi：
更新日期：1983-01-01 00:00:00
abstract：OBJECTIVES:The objective of this study was to investigate the patient characteristics and outcomes in 1406 patients undergoing intra-aortic balloon pump (IABP) counterpulsation. METHODS:Between 1998 and 2008, 1406 consecutive patients were recorded in a prospective database. Based on the main clinical indication for I...
journal_title：Acta cardiologica
pub_type： 杂志文章
doi：10.1080/ac.66.6.2136953
更新日期：2011-12-01 00:00:00
abstract：:Conventional repair of pararenal aortic aneurysms has been a technically challenging operation, with a significant morbidity rate of 28-35%. Endovascular stent grafting requires satisfactory landing zones for stent graft anchoring. Therefore, pararenal abdominal aortic aneurysms are usually contraindicated for this pr...
journal_title：Acta cardiologica
pub_type： 杂志文章
doi：10.1080/ac.69.4.3036661
更新日期：2014-08-01 00:00:00
abstract：OBJECTIVE:Pseudoxanthoma elasticum (PXE) is an autosomal recessive disorder, characterized by extensive mineralization of connective tissues and fragmentation of elastin fibres. PXE patients may sporadically suffer from severe cardiovascular complications caused by accelerated atherosclerosis. Consistent with this find...
journal_title：Acta cardiologica
pub_type： 杂志文章
doi：10.1080/ac.69.6.1000012
更新日期：2014-12-01 00:00:00
abstract：AIM:The purpose of this study was to investigate the role of oxidant stress in the clinical process and pathogenesis of acute rheumatic fever (ARF). MATERIAL AND METHODS:The study included 33 children with ARF and 20 healthy control subjects. The diagnosis of ARF was established according to the Jones Criteria. Malond...
journal_title：Acta cardiologica
pub_type： 杂志文章
doi：10.2143/AC.65.1.2045889
更新日期：2010-02-01 00:00:00
abstract：:A follow-up study was carried out in 98 patients with congestive cardiomyopathy using clinical data and M-mode echocardiography. 59 patients survived (mean follow-up period 18 months), 39 patients died (mean survival period 12.6 months). Median survival time was 3 years. Prognosis was unfavorably affected by ECG signs...
journal_title：Acta cardiologica
pub_type： 杂志文章
doi：
更新日期：1981-01-01 00:00:00
abstract：:Whereas effective strategies are available to treat acute cellular cardiac rejection, humoral rejection, also called vascular or antibody-mediated rejection, is more difficult to manage. Antibody-mediated (non-cellular) rejections (AMR) are rare and few successfully treated cases have been described in the literature....
journal_title：Acta cardiologica
pub_type： 杂志文章,评审
doi：10.1080/ac.66.2.2071263
更新日期：2011-04-01 00:00:00
abstract：OBJECTIVE:Cardiac rehabilitation programmes result in reduced morbidity and mortality and improvement of functional class. Behaviour of natriuretic peptides coupled to these programmes is not well established. Our study's objective is to evaluate the behaviour of natriuretic peptides in a sample of patients undergoing ...
journal_title：Acta cardiologica
pub_type： 杂志文章
doi：10.1080/ac.66.5.2131091
更新日期：2011-10-01 00:00:00
abstract：:The clinical, hemodynamic findings and surgical results of forty patients with rheumatic tricuspid stenosis are presented. It is concluded that tricuspid stenosis is a frequent lesion. Its signs should be sought carefully and documented by simultaneous measurements of the right ventricular diastolic and right atrial p...
journal_title：Acta cardiologica
pub_type： 杂志文章
doi：
更新日期：1978-01-01 00:00:00
abstract：OBJECTIVE:The present study was designed to examine the changes of MMP-2/TIMP-2 in the hearts of streptozotocin-induced diabetic rats and gain insight into their roles in extracellular matrix (ECM) remodelling on an experimental animal model of diabetic cardiomyopathy. METHODS AND RESULTS:Sixteen male Wistar rats were...
journal_title：Acta cardiologica
pub_type： 杂志文章
doi：10.2143/AC.62.5.2023412
更新日期：2007-10-01 00:00:00
abstract：BACKGROUND:Recent evidence suggests that there are ethnic variations in atrial fibrillation (AF) susceptibility and incidence following acute myocardial infarction (AMI). OBJECTIVES:The aim of this study was to evaluate the incidence and predictors of AF in the setting of AMI in Middle Eastern Arab and South Asian pat...
journal_title：Acta cardiologica
pub_type： 杂志文章
doi：10.1080/ac.68.2.2967275
更新日期：2013-04-01 00:00:00
abstract：:We describe two cases of Duchenne's cardiomyopathy with severe cardiac dysfunction, sporadic episodes of myoglobinuria induced by effort and increased levels of serum creatine kinase. Very mild signs of skeletal myopathy were clinically evident. Left ventriculography showed diffuse severe hypokinesia. Skeletal muscle ...
journal_title：Acta cardiologica
pub_type： 杂志文章
doi：10.2143/AC.61.4.2017311
更新日期：2006-08-01 00:00:00
abstract：OBJECTIVES:Lectin-like oxidized low-density lipoprotein receptor-1 (LOX-1) appears to be involved in atherosclerotic plaque vulnerability and rupture. In this study, we aimed to evaluate the utility of serum LOX-1 levels in the diagnosis and assessment of left ventricular systolic HF and LOX-1’s relationship with serum...
journal_title：Acta cardiologica
pub_type： 杂志文章
doi：10.2143/AC.71.2.3141848
更新日期：2016-04-01 00:00:00
abstract：:Though cardiac involvement is a frequent finding in patients with Duchenne muscular dystrophy (DMD) at the wheel-chair-bound stage, left ventricular hypertrabeculation (LVHT) has not been reported. The patient is a 28-year-old male with the typical clinical features of end stage DMD. Since the age of 16 years he requi...
journal_title：Acta cardiologica
pub_type： 杂志文章
doi：10.2143/AC.60.4.2004996
更新日期：2005-08-01 00:00:00
abstract：BACKGROUND:The available literature has not been able to demonstrate the exact association between preoperative statin therapy and the reduction in the rates of major adverse cardiac and cerebrovascular events (MACCE). The aim of this study is to explore these unanswered questions. METHODS:A review of patients having ...
journal_title：Acta cardiologica
pub_type： 杂志文章
doi：10.2143/AC.64.2.2036146
更新日期：2009-04-01 00:00:00
abstract：OBJECTIVE:The aim of this paper was to investigate the association between levels of HO-1 expression and angiographic morphology as well as the quantity of coronary lesions in patients with coronary heart disease (CHD). METHODS:110 patients with CHD were diagnosed by coronary angiography which contained coronary lesio...
journal_title：Acta cardiologica
pub_type： 杂志文章
doi：10.2143/AC.61.3.2014831
更新日期：2006-06-01 00:00:00
abstract：:A clinical, electrocardiographic and coronarographic study of ten cases shows that surelevation of ST-segment during exercise (without any signs of infarction) correspond to very different clinical situations of anatomical state of coronary vessels, occurrence of coronary spasm and evolution of the ischemic disease. "...
journal_title：Acta cardiologica
pub_type： 杂志文章
doi：
更新日期：1977-01-01 00:00:00
abstract：:Meningitis due to Neisseria meningitidis occurred in a young man. On admission, he was in septic shock and the electrocardiogram revealed convex upwards ST-segment elevation in inferior and lateral leads. Rapid and complete normalisation of the ECG was observed and the patient had a favourable evolution with intensive...
journal_title：Acta cardiologica
pub_type： 杂志文章
doi：10.2143/AC.56.5.2005695
更新日期：2001-10-01 00:00:00
abstract：OBJECTIVE:dobutamine stress echocardiography (DSE) in patients with ischaemic cardiomyopathy. We explored the accuracy of resting echocardiographic and tissue Doppler parameters to predict a positive response by low-dose METHODS AND RESULTS:We enrolled 100 consecutive patients with prior myocardial infarction, and a l...
journal_title：Acta cardiologica
pub_type： 杂志文章
doi：10.1080/ac.67.6.2184672
更新日期：2012-12-01 00:00:00
abstract：:European Society of Cardiology (ESC) National Society Cardiovascular Journals (NSCJs) are high-quality biomedical journals focused on cardiovascular diseases. The Editors' Network of the ESC devises editorial initiatives aimed at improving the scientific quality and diffusion of NSCJ. In this article we will discuss o...
journal_title：Acta cardiologica
pub_type： 杂志文章,评审
doi：10.1080/ac.68.5.2994483
更新日期：2013-10-01 00:00:00
abstract：:In chronic aorto-iliac occlusive disease, pre-existing renal artery stenosis may give rise to sufficient development of collateral blood flow and prevent ischaemic symptoms for a long time and therefore may cause delay in diagnosis. An early diagnosis of aorto-iliac disease is necessary in order to avoid fatal outcome...
journal_title：Acta cardiologica
pub_type： 杂志文章
doi：10.2143/AC.64.3.2038035
更新日期：2009-06-01 00:00:00
