Abstract:
BACKGROUND:Available clinical and angiographic scoring systems fail to predict clinical outcomes in real-world patients undergoing revascularization of the unprotected left main coronary artery (ULMCA). METHODS:We prospectively assessed major adverse cardiac and cerebrovascular events (MACCE) in a real-world population undergoing percutaneous coronary intervention (PCI) for ULMCA disease. Cumulative risk-adjusted mortality in our patients was compared with expected mortality at 30 days based on logistic EuroSCORE and SYNTAX SCORE. Similarly, we plotted cumulative risk-adjusted MACCE at 1 year based on SYNTAX SCORE. Finally, both scores were combined in 1 year Global Risk Charts, including the use of drug-eluting stents (DES), diabetic status, and several factors precluding coronary surgery. RESULTS:Over a 12-year period, 240 patients underwent elective (76%) or urgent (24%) PCI of the ULMCA. Median logistic EuroSCORE and SYNTAX SCORE were 8.7% (3.5; 21) and 23% (14; 31). During the first year of follow-up, 89 patients presented MACCE (37.1%) (46 deaths [19.2%], 18 acute myocardial infarctions [7.5%], 45 revascularizations [18.8%] and 4 strokes [1.7%]). Cumulative risk-adjusted mortality based on individual logistic EuroSCORE and SYNTAX SCORE pointed towards significant overestimation (+19 deaths) and underestimation (-35 deaths) of risk by these respective scoring systems. Similarly, the anatomic SYNTAX SCORE largely underestimated cumulative risk-adjusted MACCE (-60 MACCE). The Global Risk Charts provided a more balanced view on 1-year clinical outcome. CONCLUSION:An integrated risk evaluation combining EuroSCORE, SYNTAX SCORE, diabetic status, stent type and general condition, may predict outcomes more accurately awaiting validation in a larger and multicentre setting.
journal_name
Acta Cardioljournal_title
Acta cardiologicaauthors
Kayaert P,Desmet W,Sinnaeve P,Adriaenssens T,Coosemans M,Ferdinande B,Dubois Cdoi
10.1080/ac.67.5.2174124subject
Has Abstractpub_date
2012-10-01 00:00:00pages
503-13issue
5eissn
0001-5385issn
1784-973Xjournal_volume
67pub_type
杂志文章,多中心研究abstract::Nineteen asymptomatic patients affected by isolated chronic aortic regurgitation received 20 mg of nifedipine sublingually: the acute hemodynamic effects of nifedipine were evaluated by combined cross-sectional and Doppler echocardiography. To assess variations in the regurgitant flow volume, the flow volume across th...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:
更新日期:1993-01-01 00:00:00
abstract:OBJECTIVE:Few studies described the home blood pressure (HBP) in young children. Using intrafamilial correlations of blood pressure as research focus, we assessed the feasibility of HBP monitoring in this age group. METHODS:We enrolled 382 mothers (mean age 38.8 years) and singletons (7.0 years) in theTohoku Study of ...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.1080/ac.67.4.2170687
更新日期:2012-08-01 00:00:00
abstract::Veno-Venous Extracorporeal Membrane Oxygenation (VV-ECMO) provides a bridge to recovery in patients with acute respiratory failure due to the acute respiratory distress syndrome (ARDS). Survival in ARDS has improved over 15 years, and VV-ECMO may rescue even the most severe of these patients. Predictors of survival on...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.1080/00015385.2020.1841971
更新日期:2021-01-04 00:00:00
abstract:OBJECTIVE:Mild reductions in iodine concentration could reduce acute side effects after intraarterial contrast media administration without affecting the quality of coronary artery images. This study was designed to show the equivalence in terms of image quality of two nonionic low-osmolar monomers, iobitridol 350 and ...
journal_title:Acta cardiologica
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.2143/AC.65.4.2053896
更新日期:2010-08-01 00:00:00
abstract::Atherosclerotic involvement of extracoronary arteries in patients undergoing myocardial revascularization can cause severe postoperative complications and increase postoperative mortality. Between January and November 1998, routine preoperative echo-Doppler study of carotid vessels, abdominal aorta and iliac-femoral a...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.2143/AC.56.2.2005623
更新日期:2001-04-01 00:00:00
abstract:OBJECTIVES:Angiotensin-converting enzyme (ACE) is a key enzyme in the production of angiotensin II and thus may participate in the modulation of cardiac growth. The cloning of the ACE gene has made it possible to identify a deletion (D)-insertion (I) polymorphism that appears to affect the level of serum ACE activity. ...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.2143/AC.60.2.2005025
更新日期:2005-04-01 00:00:00
abstract:OBJECTIVES:The objective of this study is to evaluate the prevalence of HR2 polymorphism among patients with pulmonary embolism (PE) and healthy subjects. BACKGROUND:Polymorphism in the factor V gene named HR2 has been described as a possible risk factor for venous thromboembolism (VTE) development. Contradictive resu...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.2143/AC.70.6.3120184
更新日期:2015-12-01 00:00:00
abstract::The present study aims at evaluating the acute hemodynamic effects of external and internal (3 and 15 mA) pacing on 30 patients with severe cardiac failure. The global and regional ejection fraction were calculated by repeated radionuclide ventriculography at rest (control) and during increasing pacing rates. Blood pr...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:
更新日期:1994-01-01 00:00:00
abstract::Between March 1982 and March 1991, 225 heart transplantations (HTx) have been performed in 220 patients suffering end stage cardiac disease. Thirteen percent were females and 87% were males. Age range was from 5 to 68 years. The underlying cardiac disease was ischemic cardiopathy in 51.5%, congestive dilated cardiomyo...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:
更新日期:1991-01-01 00:00:00
abstract::Most accessory pathways in pre-excitation syndrome are capable of antegrade conduction from atrium to ventricle, and identified by characteristic ECG abnormalities such as a delta wave (ventricular pre-excitation) and a shortened PR interval.Therefore, the traditional diagnosis method is to detect the initial changes ...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.1080/ac.68.2.2967285
更新日期:2013-04-01 00:00:00
abstract::We present a 64-year-old woman who was brought to the emergency department after suffering a motor vehicle accident, involving multiple soft tissue and bone trauma. Even though she was free from cardiovascular symptoms for the last three years, her past medical history of aorto-coronary bypass surgery prompted preoper...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.2143/AC.58.2.2005271
更新日期:2003-04-01 00:00:00
abstract::We report the M-mode and two-dimensional echocardiographic findings in a patient with familial amyloidosis. The diagnosis was made by the clinical picture and histologic evidence of amyloid in peripheral nerve biopsy. Though the patient had no clinical sign of heart failure, extensive involvement of the heart was demo...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:
更新日期:1981-01-01 00:00:00
abstract::Left ventricular-right atrial communication is a relatively rare surgically corrigible congenital heart defect. We report a case with review of the literature. ...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:
更新日期:1987-01-01 00:00:00
abstract::Hereditary diseases under the age of 35 are the most common underlying heart disease, leading to sudden cardiac death (SCD) in competitive sports, while in older people, atherosclerotic coronary artery disease (CAD) is the main cause. The following preventive measures are recommended: (a) The pre-participation cardiov...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.1080/00015385.2020.1867388
更新日期:2021-01-08 00:00:00
abstract::The increasing number of amateur sportsmen enhances the need for a correct evaluation of subjects suspected of overt and mild cardiac disease. Out of 4000 athletes, 72 subjects were clinically preselected by the sport doctor during an annual routine examination. They were studied with mono and 2D echo, pulsed color (P...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:
更新日期:1992-01-01 00:00:00
abstract::Background: Defibrillation threshold testing (DT) following implantable cardioverter defibrillator (ICD) implantation has not shown to improve mortality. However, the impact of DT on burden of heart failure (HF) hospitalisations has not been well defined.Methods: We studied retrospectively consecutive patients who und...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.1080/00015385.2019.1630586
更新日期:2020-06-01 00:00:00
abstract:OBJECTIVE:This study sought to evaluate the potential prognostic usefulness of QT dispersion (QTd) in patients with unstable angina. METHODS AND RESULTS:QTd was calculated and plasma troponin T (TnT) level was measured and rest perfusion imaging with Tc-99m sestamibi was performed in 62 patients admitted with chest pa...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.2143/AC.59.3.2005183
更新日期:2004-06-01 00:00:00
abstract::Sixteen patients were examined hemodynamically with echocardiography, calibrated apexcardiography, and systolic time intervals before treatment, after 1 week treatment with amiodarone 600 mg daily and after 2-4 months treatment with 300 mg daily. During the treatment thyroid function was controlled. The echocardiogram...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:
更新日期:1984-01-01 00:00:00
abstract::Endothelial cells release both relaxing and contracting factors that modulate vascular smooth muscle tone and also participate in the pathophysiology of essential hypertension. Endothelium-dependent vasodilation is regulated primarily by nitric oxide but also by an unidentified endothelium-derived hyperpolarizing fact...
journal_title:Acta cardiologica
pub_type: 杂志文章,评审
doi:10.2143/AC.55.4.2005744
更新日期:2000-08-01 00:00:00
abstract:OBJECTIVE:The mechanisms of the different haemodynamic and clinical responses to dobutamine infusion in mitral stenosis (MS) are not clearly established. The aim of this study was to evaluate the relation between left atrial (LA) function and haemodynamic response in patients with MS during dobutamine infusion. METHOD...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.2143/AC.58.6.2005319
更新日期:2003-12-01 00:00:00
abstract::The authors present a case of symptomatic non-sustained ventricular tachycardia induced by mechanical irritation of the outflow tract of the right ventricle by a loop in a permanent ventricular pacing lead. Reposition of the lead eliminated the rhythm disturbance. ...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.2143/AC.57.1.2005375
更新日期:2002-02-01 00:00:00
abstract::Pulmonary dissemination of a cardiac cyst is a rare condition. In the present study, we report a case of a 20-year-old patient with cardiac hydatosis located in the interventricular septum, which was previously diagnosed and treated as pulmonary hydatid disease. Diagnosis was made by spiral computed tomography and tre...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.2143/AC.58.5.2005309
更新日期:2003-10-01 00:00:00
abstract::Objective Heart fatty acid binding protein (HFABP) is a low-molecular-weight free protein that is abundant in the intracytoplasmic space of myocytes. Due to its unique features, serum HFABP levels may increase in myocardial ischaemia. The aim of this study was to evaluate the effect of myocardial ischaemia induced by ...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.1080/00015385.2017.1291181
更新日期:2017-04-01 00:00:00
abstract:OBJECTIVE:Cardiac resynchronization therapy (CRT), combined with optimal medical therapy (OMT), is an established treatment for patients with advanced chronic heart failure (ACHF). In ACHF, carvedilol at the dose used in clinical trials, reduces morbidity and mortality. However, patients often do not tolerate the drug ...
journal_title:Acta cardiologica
pub_type: 临床试验,杂志文章
doi:10.1080/ac.66.5.2131081
更新日期:2011-10-01 00:00:00
abstract::Background: Few data are available on long-term atherothrombotic events after percutaneous transluminal angioplasty (PTA) for peripheral arterial disease (PAD). Restenosis after PTA may be a marker of a more aggressive atherothrombosis. Aim: To ascertain whether restenosis detected by duplex sonography (DUS) after PTA...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.1080/00015385.2019.1653565
更新日期:2019-08-15 00:00:00
abstract::Purulent pericarditis is rarely the primary site of bacterial infection. It is usually a complication of an infection originating elsewhere in the body, arising by contiguous spread or haematogenous dissemination.This paper, however, describes a previously healthy young man, who developed a purulent streptococcal peri...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.2143/AC.57.5.2005459
更新日期:2002-10-01 00:00:00
abstract:AIM:The purpose of this study was to investigate the role of oxidant stress in the clinical process and pathogenesis of acute rheumatic fever (ARF). MATERIAL AND METHODS:The study included 33 children with ARF and 20 healthy control subjects. The diagnosis of ARF was established according to the Jones Criteria. Malond...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.2143/AC.65.1.2045889
更新日期:2010-02-01 00:00:00
abstract:BACKGROUND:The coronary slow flow phenomenon is an angiographic finding characterized by delayed distal vessel opacification in the absence of significant epicardial coronary disease, and is an important clinical entity because it may be the cause of angina at rest or during exercise, acute myocardial infarction, and h...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.2143/AC.63.5.2033224
更新日期:2008-10-01 00:00:00
abstract::The authors report nine surgical attempts in ventricular septal rupture following myocardial infarction and compare their experience with data from the literature. Two of the three long-term successes have been obtained by the association of infarcectomy and myocardial revascularisation to the repair of the septal rup...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:
更新日期:1975-01-01 00:00:00
abstract:OBJECTIVES:The purpose of this study is to determine plasma fibronectin level and its relationships with plasma lipids, lipoproteins and C-reactive protein (CRP) levels in patients with dyslipidaemia during lipid-lowering therapy. METHODS:Plasma levels of fibronectin, CRP, fibrinogen, lipids and lipoproteins in 38 pat...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.2143/AC.57.6.2005466
更新日期:2002-12-01 00:00:00