Abstract:
:Objective In modern cardiology practice, implantation of cardiac electronic devices in patients taking anticoagulant or antiplatelet therapy is a common clinical scenario. Bleeding complications are of particular concern in this patient population and pocket haematoma is one of the most frequent complications. We sought to determine the relationship between periprocedural antiplatelet/anticoagulant therapy and pocket haematoma formation in patients undergoing cardiac implantable electronic device (CIED) implantation. Methods We conducted a retrospective study including 232 consecutive patients undergoing CIED implantation in the department of cardiology of the Medipol University Hospital. Patients were divided into six groups: clopidogrel group (n = 12), acetylsalicylic acid (ASA) group (n = 73), ASA + clopidogrel group (n = 29), warfarin group (n = 34), warfarin + ASA group (n = 21) and no antiplatelet-anticoagulant therapy group as the control group (n = 63). CIED implantations were stratified under four subtitles including implantable cardioverter/defibrillator (ICD), cardiac resynchronization therapy (CRT), permanent pacemaker and the last group as either device upgrade or generator replacement. Results The mean age of the patients was 63 ± 14 years and 140 patients were male (60.3%). A pocket haematoma was documented in 6 of 232 patients (2.6%). None of the patients with pocket haematoma needed pocket exploration or blood transfusion. The type of the device did not have a significant effect on pocket haematoma incidence (P = 0.250). Univariate logistic regression showed that platelet level and ASA plus clopidogrel use were significantly associated with haematoma frequency after CIED implantations, respectively (OR: 0.977, CI 95% [0.958-0.996]; OR: 16.080, CI 95% [2.801-92.306]). Multivariate analysis revealed that dual antiplatelet treatment (β = 3.016, P = 0.002, OR: 2.410, 95% CI [3.042-136.943]) and baseline platelet level (β = -0.027, p:0.025, OR: 0.974, 95% CI [0.951-0.997]) were independent risk factors for pocket haematoma formation. Conclusion Dual antiplatelet therapy and low platelet levels significantly increased the risk of pocket haematoma formation in patients undergoing CIED implantations.
journal_name
Acta Cardioljournal_title
Acta cardiologicaauthors
Demir GG,Guler GB,Guler E,Güneş H,Kizilirmak F,Karaca İO,Omaygenç MO,Çakal B,Olgun E,Savur U,Ibisoglu E,Barutçu I,Kiliçaslan Fdoi
10.1080/00015385.2017.1281539subject
Has Abstractpub_date
2017-02-01 00:00:00pages
47-52issue
1eissn
0001-5385issn
1784-973Xjournal_volume
72pub_type
杂志文章abstract::Left ventricular aneurysms are common in clinical practice. Although their underlying aetiology is generally clear by the clinical context, it can be hard to define the exact cause in some cases. We report a case of a patient in whom cardiac MRI provided important information about the differential diagnosis of a left...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.1080/ac.66.4.2126612
更新日期:2011-08-01 00:00:00
abstract:OBJECTIVE:The beneficial effect of pentoxifylline (PTX) on ischaemic-reperfusion injury was assessed in a rat model of transient global cerebral ischaemia. DESIGN:Randomized, controlled, prospective study. SETTING:University research laboratory. SUBJECTS:Thirty-six male Wistar albino rats. INTERVENTIONS:Ischaemia w...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:
更新日期:1998-01-01 00:00:00
abstract::The purpose of the present study was to determine whether the cardiorespiratory variables measured during an exercise test with a continuously increasing workload (ramp) protocol are reproducible and to compare them to the values obtained with a step-wise incremental (James) protocol. Twenty normal adolescents and you...
journal_title:Acta cardiologica
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1996-01-01 00:00:00
abstract:OBJECTIVE:The levels of adiponectin, an anti-atherogenic protein, are decreased in patients with coronary artery disease. Syndrome X is associated with endothelial dysfunction, which is a key feature in the evolution of atherosclerosis. We sought to determine whether serum adiponectin levels are decreased in patients w...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.2143/AC.65.2.2047056
更新日期:2010-04-01 00:00:00
abstract::Within an epidemiological study on coronary heart disease (CHD) (alive) two samples of middle aged men living in two rural areas of Northern and Central Italy, two subgroups of individuals aged 51-59 (alive), free from CHD (alive) belonging to different generations have been identified. Group A (n = 593) was followed-...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:
更新日期:1985-01-01 00:00:00
abstract::This is a review of the effects of E on the symptoms of CHF which affect patients' (pts) quality of life and the signs associated with pts' prognosis. The review is based on clinical studies which were included in the New Drug Application for Vasotec (enalapril maleate, MSD) in the United States. There were 3 open-lab...
journal_title:Acta cardiologica
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1991-01-01 00:00:00
abstract::Pulmonary dissemination of a cardiac cyst is a rare condition. In the present study, we report a case of a 20-year-old patient with cardiac hydatosis located in the interventricular septum, which was previously diagnosed and treated as pulmonary hydatid disease. Diagnosis was made by spiral computed tomography and tre...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.2143/AC.58.5.2005309
更新日期:2003-10-01 00:00:00
abstract:BACKGROUND:Cardiac rehabilitation for ischaemic heart disease effectively reduces cardiovascular readmission rate and mortality. Current uptake rates however, remain low. This study assesses the social and economic impact of increasing centre-based cardiac rehabilitation uptake and the additional value of cardiac teler...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.1080/00015385.2017.1361892
更新日期:2018-06-01 00:00:00
abstract:OBJECTIVE:To test the hypothesis that the circulating white blood cell (WBC) and neutrophil counts are related to left ventricular (LV) indices in patients with the same risk area for acute myocardial infarction (AMI), we examined 100 consecutive AMI patients who had the culprit lesion at segment 6 according to the Ame...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.2143/AC.59.5.2005229
更新日期:2004-10-01 00:00:00
abstract::Background: The objective was to explore the value of serum carbohydrate antigen 125 (CA125) combined with N-terminal pro B-type natriuretic peptide (NT-proBNP) in predicting the clinical prognosis of patients with acute heart failure (AHF).Methods: We prospectively observed 213 patients with AHF. CA125 (U/ml) and NT-...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.1080/00015385.2020.1769347
更新日期:2020-06-10 00:00:00
abstract:OBJECTIVE:Pseudoxanthoma elasticum (PXE) is an autosomal recessive disorder, characterized by extensive mineralization of connective tissues and fragmentation of elastin fibres. PXE patients may sporadically suffer from severe cardiovascular complications caused by accelerated atherosclerosis. Consistent with this find...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.1080/ac.69.6.1000012
更新日期:2014-12-01 00:00:00
abstract::Veno-Venous Extracorporeal Membrane Oxygenation (VV-ECMO) provides a bridge to recovery in patients with acute respiratory failure due to the acute respiratory distress syndrome (ARDS). Survival in ARDS has improved over 15 years, and VV-ECMO may rescue even the most severe of these patients. Predictors of survival on...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.1080/00015385.2020.1841971
更新日期:2021-01-04 00:00:00
abstract:UNLABELLED:The aim of study was to determine the significance of the best echocardiographic parameters for assessing the severity of mitral regurgitation (MR). METHODS:The study population consisted of 107 patients, mean age 52 +/- 7 y with chronic isolated non-ischaemic MR. Quantification of the MR was performed usin...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.2143/AC.64.2.2036136
更新日期:2009-04-01 00:00:00
abstract::Background: Defibrillation threshold testing (DT) following implantable cardioverter defibrillator (ICD) implantation has not shown to improve mortality. However, the impact of DT on burden of heart failure (HF) hospitalisations has not been well defined.Methods: We studied retrospectively consecutive patients who und...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.1080/00015385.2019.1630586
更新日期:2020-06-01 00:00:00
abstract:OBJECTIVE:The mechanism underlying recurrence after successful ablation of ventricular arrhythmias (VAs) was unclear. Spectrum analysis can help to identify near-field activation. The purpose of this study was to quantify the changes of near-field activation in response to ablation at the VAs origin in the aortic root ...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.1080/00015385.2017.1324658
更新日期:2018-02-01 00:00:00
abstract:OBJECTIVES:The role of adenosine as a cardioprotective agent is well known and recent experimental studies suggest that impairment of adenosine-related signal transduction contributes to the pathophysiology of chronic heart failure. The recent observation of an association between ADA, genetic polymorphism and coronary...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.1080/ac.69.1.3011343
更新日期:2014-02-01 00:00:00
abstract:OBJECTIVE:The aortic distensibility index, as a measure of vascular function, can serve as a marker of coronary artery disease severity. This study explores the feasibility of using the non-invasively measured index as an indicator of severity of coronary stenosis. METHODS:One hundred patients with normal left ventric...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.1080/ac.70.4.3096895
更新日期:2015-08-01 00:00:00
abstract:OBJECTIVE:Elevated mean platelet volume predicts restenosis after percutaneous transluminal coronary angioplasty but its effect on the development of in-stent restenosis is not known. We assessed the effect of mean platelet volume measured before coronary stent implantation for stable angina pectoris on subsequent deve...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.2143/AC.59.4.2005204
更新日期:2004-08-01 00:00:00
abstract::Background: Cardiovascular rehabilitation and retraining seek to increase cardiorespiratory fitness and to manage certain risk factors such as smoking, hypercholesterolaemia and sedentary lifestyle. Such lifestyle changes can be influenced by a combination of health determinants. Aim: The purpose of this study is to a...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.1080/00015385.2019.1639269
更新日期:2019-07-17 00:00:00
abstract::Endothelial cells release both relaxing and contracting factors that modulate vascular smooth muscle tone and also participate in the pathophysiology of essential hypertension. Endothelium-dependent vasodilation is regulated primarily by nitric oxide but also by an unidentified endothelium-derived hyperpolarizing fact...
journal_title:Acta cardiologica
pub_type: 杂志文章,评审
doi:10.2143/AC.55.4.2005744
更新日期:2000-08-01 00:00:00
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journal_title:Acta cardiologica
pub_type: 杂志文章
doi:
更新日期:1998-01-01 00:00:00
abstract:OBJECTIVE:A prospective randomized multicentre pilot trial, comparing stenting with balloon angioplasty as a treatment for coronary lesions, located in a bifurcation was performed. METHODS AND RESULTS:After balloon dilatation, with a < 30% residual stenosis in the main vessel and < 50% residual stenosis in the side br...
journal_title:Acta cardiologica
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.2143/AC.60.4.2004986
更新日期:2005-08-01 00:00:00
abstract::A total of 10 cases of non-bacterial thrombotic endocarditis (NBTE) were found among 1640 adult patients, autopsied in a 24-year period. Eight out of 10 patients had an underlying malignant tumor, NBTE was more common in cancer patients than in patients without malignancy (1.25% vs 0.2%, P less than 0.05). Patients wi...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:
更新日期:1991-01-01 00:00:00
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journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.2143/AC.70.6.3120184
更新日期:2015-12-01 00:00:00
abstract::Background: Quality indicators (QIs) are used to measure and evaluate quality of care. However, QIs to evaluate care for HF patients in general practice in Belgium are lacking. Therefore, this study aimed to determine which QIs, rooted in the electronic health record (EHR), are useful to monitor quality of care for pa...
journal_title:Acta cardiologica
pub_type: 共识发展会议,杂志文章,评审
doi:10.1080/00015385.2018.1492659
更新日期:2019-08-01 00:00:00
abstract:PURPOSE:We aimed to investigate the role of QRS duration on the surface electrocardiogram (ECG) in predicting response to levosimendan therapy in patients with acute systolic heart failure. METHODS:Patients with an ejection fraction (EF) lower than 35% who required intravenous inotropic support despite optimal heart f...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.1080/ac.67.3.2160721
更新日期:2012-06-01 00:00:00
abstract::Sixteen patients were examined hemodynamically with echocardiography, calibrated apexcardiography, and systolic time intervals before treatment, after 1 week treatment with amiodarone 600 mg daily and after 2-4 months treatment with 300 mg daily. During the treatment thyroid function was controlled. The echocardiogram...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:
更新日期:1984-01-01 00:00:00
abstract::Between January 1970 and August 1974, eleven postinfarction patients underwent left ventricular aneurysmectomy for refractory tachyarrhythmias. Ten suffered from ventricular tachycardias and one from supraventricular tachycardia. All had localized aneurysms and normal contractions of the surrounding myocardium on angi...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:
更新日期:1976-01-01 00:00:00
abstract:OBJECTIVE:Our study is designed to evaluate the plasma BNP levels in patients with pure MS and its possible correlation with clinical and echocardiographic parameters of the disease. METHODS AND RESULTS:The study included 29 patients (27 women, 2 men, mean age 43.4 +/- 11.8 y) with pure mitral valve stenosis in sinus ...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.1080/ac.67.1.2146566
更新日期:2012-02-01 00:00:00
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journal_title:Acta cardiologica
pub_type: 杂志文章
doi:
更新日期:1991-01-01 00:00:00