Abstract:
PURPOSE:With the aim of recommending proper anticoagulation for patients with atrial fibrillation (AF) and diabetes mellitus, we performed the network meta-analysis comparing the non-vitamin K antagonist oral anticoagulants (NOACs) and warfarin in terms of efficacy (stroke or systemic embolism) and safety (major bleeding) outcome. METHODS:A systematic search of PubMed, EMBASE, Web of Science and Cochrane Library was performed with the items "dabigatran, edoxaban, apixaban, rivaroxaban, warfarin, AF and diabetes mellitus". On the basis of R (version 3.5.1, R Foundation for Statistical Computing) and JAGS (version 4.3.0) to perform the network meta-analysis, our work was also conducted with the help of NetMetaXL (version1.6.1) and winBUGS (version1.4.3) to obtain the cumulative ranking curve (SUCRA) of treatments. RESULTS:With respect to the most effective drug for preventing systemic embolism or stroke, there was a high probability that dabigatran150 (SUCRA 0.88) would ranked first, followed by apixaban (SUCRA 0.63), dabigatran110 (SUCRA 0.59) and rivaroxaban (SUCRA 0.51). In comparison, probability of ranking the safest drug for preventing major bleeding was edoxaban (SUCRA 0.94), followed by dabigatran110 (SUCRA 0.59) and rivaroxaban (SUCRA 0.52). CONCLUSION:In patients suffering from AF and diabetes, dabigatran 110 mg (bid) was more likely to become the choice for its performance on preventing systemic embolism or stroke and major bleeding, followed by rivaroxaban 20 mg (QD).
journal_name
Acta Cardioljournal_title
Acta cardiologicaauthors
Jin H,Zhu K,Wang L,Zhi Hdoi
10.1080/00015385.2020.1869671subject
Has Abstractpub_date
2021-01-12 00:00:00pages
1-10eissn
0001-5385issn
1784-973Xpub_type
杂志文章abstract:OBJECTIVE:The main function of hepatic lipase (HL) with respect to high-density lipoprotein (HDL) is hydrolysis of phospholipids and triglycerides. The -514C-->T polymorphism in the promoter region of the hepatic lipase gene affects HL activity. We aimed to investigate the association between the frequency of the -514C...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.2143/AC.63.2.2029528
更新日期:2008-04-01 00:00:00
abstract:OBJECTIVE:Red cell distribution width (RDW) is a measure of variation in the volume of circulating erythrocytes and has recently emerged as a powerful prognostic marker in heart failure. We studied the effect of 5-month, home-based cardiac rehabilitation on RDW. METHODS AND RESULTS:Sixty-two patients (age: median 67 y...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.1080/ac.68.6.8000009
更新日期:2013-12-01 00:00:00
abstract::A follow-up study was carried out in 98 patients with congestive cardiomyopathy using clinical data and M-mode echocardiography. 59 patients survived (mean follow-up period 18 months), 39 patients died (mean survival period 12.6 months). Median survival time was 3 years. Prognosis was unfavorably affected by ECG signs...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:
更新日期:1981-01-01 00:00:00
abstract:OBJECTIVES:Heart failure (HF) is a lethal disorder most common in blacks. Available treatment options have little impact on prognosis, making primary prevention a priority. We aimed to describe the spectrum of established HF risk factors and clinical features in Nigerian adults. METHODS:We recruited consecutive adults...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.2143/AC.63.4.2033041
更新日期:2008-08-01 00:00:00
abstract::During inflammation, several cell types synthesize and secrete phospholipase A2 that catalyses lipid oxidation in LDL. Myeloperoxidase, a haeme protein secreted by activated phagocytes, oxidizes L-tyrosine to a tyrosyl radical that is a physiological catalyst for the initiation of lipid oxidation in LDL. Lipid oxidati...
journal_title:Acta cardiologica
pub_type: 杂志文章,评审
doi:10.2143/AC.59.5.2005219
更新日期:2004-10-01 00:00:00
abstract::Aim of this study was to elucidate the diagnostic significance of left axis deviation (LAD) in patients (pts) with chronic (> 6 months) left bundle branch block (LBBB). We retrospectively studied 2094 consecutive pts who underwent cardiac catheterization. All pts had left heart catheterization and coronary angiography...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:
更新日期:1997-01-01 00:00:00
abstract::Arrhythmogenic right ventricular dysplasia (ARVD) is a heart muscle disease characterized pathologically by fibrofatty replacement of right ventricular myocardium. It is further characterized by an electrical instability that precipitates ventricular arrhythmias and sudden death. The prevalence is estimated at 0.4% de...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.2143/AC.59.4.2005214
更新日期:2004-08-01 00:00:00
abstract:OBJECTIVE:The mechanisms of the different haemodynamic and clinical responses to dobutamine infusion in mitral stenosis (MS) are not clearly established. The aim of this study was to evaluate the relation between left atrial (LA) function and haemodynamic response in patients with MS during dobutamine infusion. METHOD...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.2143/AC.58.6.2005319
更新日期:2003-12-01 00:00:00
abstract:OBJECTIVE:To test the hypothesis that the circulating white blood cell (WBC) and neutrophil counts are related to left ventricular (LV) indices in patients with the same risk area for acute myocardial infarction (AMI), we examined 100 consecutive AMI patients who had the culprit lesion at segment 6 according to the Ame...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.2143/AC.59.5.2005229
更新日期:2004-10-01 00:00:00
abstract:OBJECTIVE:Elevated mean platelet volume predicts restenosis after percutaneous transluminal coronary angioplasty but its effect on the development of in-stent restenosis is not known. We assessed the effect of mean platelet volume measured before coronary stent implantation for stable angina pectoris on subsequent deve...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.2143/AC.59.4.2005204
更新日期:2004-08-01 00:00:00
abstract::Experimental demonstration that the external phonocardiogram is similar to the third derivative (rate of acceleration) of LV pressure, and that catecholamines cause a similar increase of the early systolic wave of the first derivative of LV pressure and of S1 prompted a study of the first sound during stress testing. ...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:
更新日期:1986-01-01 00:00:00
abstract:OBJECTIVE:The objective of this study was to determine similarities in the effect of yellow wine as compared to statin and the possibility that yellow wine inhibits tumour necrosis factor-α (TNF-α)-induced nitric oxide (NO) synthesis, endothelial nitric oxide synthase (eNOS), inducible nitric oxide synthase (iNOS), and...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.2143/AC.71.1.3132094
更新日期:2016-02-01 00:00:00
abstract::We describe the case of a 44-year-old man, with a history of recurrent syncopal episodes and effort angina, the latter attributed to cardiac syndrome-X, who was admitted to our department because of a syncopal episode. During his hospitalization laboratory investigations including haematologic and blood chemical findi...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:
更新日期:1999-04-01 00:00:00
abstract::To attain a long and healthy life has always been one of the major goals of humanity. The Chinese emperors, the Egyptian pharaohs and the Aztec kings all aspired to become immortal. To try to avoid mortality and to decrease morbidity at the population level is the role of public health, taken in its broadest sense, in...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:
更新日期:1999-06-01 00:00:00
abstract:INTRODUCTION:The added value of routine echocardiography, in respect to clinical examination and ECG, has received little attention. We sought to evaluate the contribution of two-dimensional echocardiography, in respect to clinical examination and ECG, in detecting left ventricular (LV) dilatation and systolic dysfunct...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.2143/AC.63.4.2033051
更新日期:2008-08-01 00:00:00
abstract::The modifications that atrial flutter determines on the phonocardiogram, apexcardiogram, carotid pulse tracing, jugular venous pulse tracing, and indirect (esophageal) left atrial pulse tracing were studied. On the basis of the data here presented and that of the literature, a polygraphic profile of atrial flutter has...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:
更新日期:1976-01-01 00:00:00
abstract::Thromboembolic events are major causes of morbidity and mortality in patients with native heart valve disease and artificial heart valves. Oral anticoagulation can reduce these complications. The indication for and intensity of oral anticoagulation depends on both, the risk for thromboembolic events and the risk of he...
journal_title:Acta cardiologica
pub_type: 杂志文章,评审
doi:
更新日期:1996-01-01 00:00:00
abstract::We investigated the clinical significance of recovery systolic blood pressure (SBP) ratio, obtained dividing the recovery SBP at 1st (R1/A) or 3rd min (R3/A) by the peak exercise SBP (before stopping), during upright bicycle exercise in 530 subjects (ranging from 17 to 73 years). Our results may be summarized as follo...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:
更新日期:1991-01-01 00:00:00
abstract:OBJECTIVE:We investigated the survival of patients who had undergone elective reconstruction of the ascending aorta for degenerative aneurysms. The long-term survival was compared to an age- and sex-matched case-control population. An analysis of risk factors, influencing survival was made. METHODS AND RESULTS:From Ma...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.1080/ac.68.4.2988887
更新日期:2013-08-01 00:00:00
abstract:BACKGROUND AND AIM:Decreased left ventricular mass index in anorexia nervosa is amply reported. The aim of this study is to identify non-burdensome predictors of reduced left yentricular mass/height (cLVM) in a cohort of adolescent restrictive anorexic girls. METHODS:This is a retrospective study of all anorexic girls...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.1080/ac.70.4.3094647
更新日期:2015-08-01 00:00:00
abstract::After D.C. countershock to terminate cardiac arrhythmias, in 3 out of 8 patients studied, an increase in both plasma myoglobin (Mb) and CK-MB (assessed by radioimmunoassay) was found. In 2 patients there was an increase of only plasma Mb and in 1 an increase of only CK-MB. In 2 cases no increase of either parameters w...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:
更新日期:1984-01-01 00:00:00
abstract::Jugular vein thrombosis (JVT) is usually secondary to central venous catheterisation, distant malignancy, hypercoagulable state or ovarian hyperstimulation syndrome. Spontaneous internal JVT is an extremely rare entity. A 61-year-old man presented with swelling of the right side of his face. An ultrasonographic scan s...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.2143/AC.64.5.2042704
更新日期:2009-10-01 00:00:00
abstract:BACKGROUND:High platelet reactivity (HPR) to clopidogrel is associated with an increased risk of ischaemic complications during and after coronary interventions and concerns up to 50% of patients undergoing PCI. AIM OF THE STUDY:The aim of the study was to identify patients with HPR to clopidogrel using bedside clinic...
journal_title:Acta cardiologica
pub_type: 临床试验,杂志文章,多中心研究
doi:10.2143/AC.70.5.3110511
更新日期:2015-10-01 00:00:00
abstract::Congenital left ventricular diverticulum is rare and usually isolated or associated with midline thoracoabdominal defects and other congenital cardiac malformations. We describe a case with a previously undescribed malformation syndrome including bilateral obstruction of the ureteropelvic junction, agenesis of corpus ...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.2143/AC.58.3.2005280
更新日期:2003-06-01 00:00:00
abstract::Left ventricular aneurysms are common in clinical practice. Although their underlying aetiology is generally clear by the clinical context, it can be hard to define the exact cause in some cases. We report a case of a patient in whom cardiac MRI provided important information about the differential diagnosis of a left...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.1080/ac.66.4.2126612
更新日期:2011-08-01 00:00:00
abstract:OBJECTIVE:Coronary stenoses of intermediate severity create difficulties in decision making when revascularization is concerned. Myocardial fractional flow reserve (mFFR), an accurate tool to identify physiological significance of individual coronary stenoses, may help solve this problem. METHODS AND RESULTS:Fifty-eig...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.2143/AC.57.5.2005449
更新日期:2002-10-01 00:00:00
abstract::A patient with unstable angina and known heart failure, and marked U wave alternans on the electrocardiogram is reported. Alternans of the U wave with no change in the QRS complex is extremely rare. The relevant literature is reviewed. ...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:
更新日期:1999-10-01 00:00:00
abstract:OBJECTIVE:Cytomegalovirus (CMV), Helicobacter pylori (H. pylori) and Chlamydia pneumoniae (C. pneumoniae) have been associated with human atherosclerosis. The reported rates of detection within atherosclerotic lesions by PCR vary widely for all of these pathogens. We investigated their presence in carotid atherosclerot...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.2143/AC.59.6.2005249
更新日期:2004-12-01 00:00:00
abstract::The case reported in this paper, besides illustrating several aspects of the eosinophilic myocarditis, documents a yet undescribed feature of the cardiac involvement in idiopathic hypereosinophilic syndrome characterized by marked basement membrane thickening of small intramyocardial vessels. We are unaware of previou...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:
更新日期:1996-01-01 00:00:00
abstract::Conventional repair of pararenal aortic aneurysms has been a technically challenging operation, with a significant morbidity rate of 28-35%. Endovascular stent grafting requires satisfactory landing zones for stent graft anchoring. Therefore, pararenal abdominal aortic aneurysms are usually contraindicated for this pr...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.1080/ac.69.4.3036661
更新日期:2014-08-01 00:00:00