Abstract:
:Nineteen asymptomatic patients affected by isolated chronic aortic regurgitation received 20 mg of nifedipine sublingually: the acute hemodynamic effects of nifedipine were evaluated by combined cross-sectional and Doppler echocardiography. To assess variations in the regurgitant flow volume, the flow volume across the mitral and aortic valves was calculated as the product of velocity-time integral multiplied by the orifice valve area. Flow volume across these valves represented the total stroke volume, and forward stroke volume, respectively: the regurgitant volume was obtained by calculating the difference between total and forward stroke volume. Nifedipine induced a redistribution of the two components of the total left ventricular stroke volume: regurgitant stroke volume decreased from 57 +/- 22 ml/beat to 46 +/- 21 ml/beat (P < 0.002), while forward stroke volume increased from 83 +/- 12 to 93 +/- 15 ml/beat (P < 0.0005), as a consequence of the reduction in systemic vascular resistance from 1513 +/- 378 to 1092 +/- 307 dynes.sec.cm-5 (P < 0.0001). The reduction of regurgitant volume was due to either a 24.8% decrease of the aortic-left ventricular mean pressure gradient during diastole (P < 0.008) or a 6% decrease of the diastolic time interval (P < 0.04). The effect of these acute changes on left ventricular loading was to induce a reduction in oxygen consumption which was expressed by a decrease in the double product (from 10176 +/- 1767 to 9444 +/- 1559 mmHg.beats/min; P < 0.002), in spite of a significant increase in heart rate. This study, therefore, shows the beneficial acute hemodynamic effect induced by nifedipine in asymptomatic patients affected by chronic aortic regurgitation and shows that Doppler-echocardiography is a useful instrument for the evaluation of hemodynamic changes immediately after the administration of drugs.
journal_name
Acta Cardioljournal_title
Acta cardiologicaauthors
Gentile F,Ornaghi M,Esposti D,Triulzi MOsubject
Has Abstractpub_date
1993-01-01 00:00:00pages
495-506issue
5eissn
0001-5385issn
1784-973Xjournal_volume
48pub_type
杂志文章abstract::Background: All previous meta-analyses including clinical outcomes after remote ischaemic conditioning (RIC) in patients with ST-elevation myocardial infarction (STEMI) treated with percutaneous coronary intervention (PCI) demonstrated that RIC significantly reduced all-cause mortality and major adverse cardiovascular...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.1080/00015385.2020.1766259
更新日期:2020-07-03 00:00:00
abstract::We present two cases of Ortner's syndrome, a syndrome with hoarseness caused by unilateral left recurrent laryngeal nerve palsy as a complication of cardiovascular diseases. In the first case, aneurysmatic dilatation of the aorta and in the second case a dilated pulmonary trunk was thought to be the cause. ...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.1080/ac.65.6.2059871
更新日期:2010-12-01 00:00:00
abstract::Objective In modern cardiology practice, implantation of cardiac electronic devices in patients taking anticoagulant or antiplatelet therapy is a common clinical scenario. Bleeding complications are of particular concern in this patient population and pocket haematoma is one of the most frequent complications. We soug...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.1080/00015385.2017.1281539
更新日期:2017-02-01 00:00:00
abstract::Between January 1970 and August 1974, eleven postinfarction patients underwent left ventricular aneurysmectomy for refractory tachyarrhythmias. Ten suffered from ventricular tachycardias and one from supraventricular tachycardia. All had localized aneurysms and normal contractions of the surrounding myocardium on angi...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:
更新日期:1976-01-01 00:00:00
abstract:BACKGROUND:Although non-adherence to medications is associated with increased cardiovascular risks, very little information is focused on the relationship between knowledge and medication adherence among patients with coronary heart disease (CHD). AIM:The purposes were to assess the relationship between medication adh...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.1080/ac.70.2.3073511
更新日期:2015-04-01 00:00:00
abstract:OBJECTIVE:The main function of hepatic lipase (HL) with respect to high-density lipoprotein (HDL) is hydrolysis of phospholipids and triglycerides. The -514C-->T polymorphism in the promoter region of the hepatic lipase gene affects HL activity. We aimed to investigate the association between the frequency of the -514C...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.2143/AC.63.2.2029528
更新日期:2008-04-01 00:00:00
abstract:AIM:We aimed to compare the incidence of contrast-induced nephropathy (CIN) between atorvastatin versus rosuvastatin in patients with ST-segment elevation myocardial infarction (STEMI) undergoing primary coronary angioplasty. METHODS:One hundred ninety-two consecutive patients, who underwent primary percutaneous inter...
journal_title:Acta cardiologica
pub_type: 杂志文章,随机对照试验
doi:10.1080/ac.68.5.2994472
更新日期:2013-10-01 00:00:00
abstract::The optimal management of high-risk patients requiring urgent or emergency noncardiac surgery when the options for further testing and evaluation are limited, is unclear. The focus of most of the literature, including the American College of Cardiology/American Heart Association guidelines, has been on patients underg...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.2143/AC.60.5.2004980
更新日期:2005-10-01 00:00:00
abstract::Transradial approach to coronary angiography is a progressive and increasingly more often used technique. Apart from its advantages, radial artery occlusion (RAO) represents the most serious drawback. Re-canalization of an iatrogenic RAO, although asymptomatic in the majority of cases, remains a discussed and challeng...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.1080/ac.67.3.2160731
更新日期:2012-06-01 00:00:00
abstract::"No-reflow" is an important complication of percutaneous coronary intervention (PCI) in the setting of acute myocardial infarction and is associated with worse outcomes. Visible thrombus on the angiogram is a significant risk factor for "no-reflow". A variety of strategies have been employed to prevent this phenomenon...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.2143/AC.60.6.2004941
更新日期:2005-12-01 00:00:00
abstract::Background: Quality indicators (QIs) are used to measure and evaluate quality of care. However, QIs to evaluate care for HF patients in general practice in Belgium are lacking. Therefore, this study aimed to determine which QIs, rooted in the electronic health record (EHR), are useful to monitor quality of care for pa...
journal_title:Acta cardiologica
pub_type: 共识发展会议,杂志文章,评审
doi:10.1080/00015385.2018.1492659
更新日期:2019-08-01 00:00:00
abstract:OBJECTIVE:This study aimed at determining the effect of percutaneous ASD closure on the AV conduction. Percutaneous closure of ostium secundum atrial septal defects (ASDs) has been widely accepted and has become the standard treatment of this malformation. However, some complications have been reported. Because of the ...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.1080/ac.66.3.2114130
更新日期:2011-06-01 00:00:00
abstract:OBJECTIVE:The aortic distensibility index, as a measure of vascular function, can serve as a marker of coronary artery disease severity. This study explores the feasibility of using the non-invasively measured index as an indicator of severity of coronary stenosis. METHODS:One hundred patients with normal left ventric...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.1080/ac.70.4.3096895
更新日期:2015-08-01 00:00:00
abstract::We describe the case of a 44-year-old man, with a history of recurrent syncopal episodes and effort angina, the latter attributed to cardiac syndrome-X, who was admitted to our department because of a syncopal episode. During his hospitalization laboratory investigations including haematologic and blood chemical findi...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:
更新日期:1999-04-01 00:00:00
abstract::Introduction Strength exercises influence the cardiovascular system by promoting autonomic adjustments induced by the increased metabolic demand and consequent increase in local blood flow. However, it is unclear whether there are differences between upper and lower limbs. We aimedto evaluate recovery of cardiac auton...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.1080/00015385.2017.1335454
更新日期:2017-08-01 00:00:00
abstract::Epidemiological information on the prevalence, incidence and natural history of intermittent claudication and peripheral vascular disease is limited, partially by the limitation of techniques of their study. The available data from the literature are review and supplemented by results from an on-going survey the ankle...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:
更新日期:1979-01-01 00:00:00
abstract::A case of pulmonary valve endocarditis in a patient with patent ductus arteriosus is reported. The diagnosis was made by echocardiographic examination. The M mode echocardiogram showed "shaggy" echoes on the pulmonic valve and the two dimensional echocardiogram disclosed a big vegetation in the right outflow tract. Th...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:
更新日期:1986-01-01 00:00:00
abstract:OBJECTIVE:The beneficial effect of pentoxifylline (PTX) on ischaemic-reperfusion injury was assessed in a rat model of transient global cerebral ischaemia. DESIGN:Randomized, controlled, prospective study. SETTING:University research laboratory. SUBJECTS:Thirty-six male Wistar albino rats. INTERVENTIONS:Ischaemia w...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:
更新日期:1998-01-01 00:00:00
abstract:UNLABELLED:We describe the clinical and echocardiographic features in 12 patients with hydatid cyst of the heart who were screened between 1985 and 2001. Presenting symptoms have a wide variability but the main symptom was precordial pain. The electrocardiogram was always abnormal and showed T wave inversion in 8 cases...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.2143/AC.60.1.2005047
更新日期:2005-02-01 00:00:00
abstract::The present study aims at evaluating the acute hemodynamic effects of external and internal (3 and 15 mA) pacing on 30 patients with severe cardiac failure. The global and regional ejection fraction were calculated by repeated radionuclide ventriculography at rest (control) and during increasing pacing rates. Blood pr...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:
更新日期:1994-01-01 00:00:00
abstract:OBJECTIVE:Left ventricular thrombus (LVT) is one of the important complications of acute anterior wall myocardial infarction (MI). Mean platelet volume (MPV) is one of the platelet indices reflecting platelet reactivity. In this present study we investigated the effect of MPV on LVT formation after primary percutaneous...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.2143/AC.69.6.1000002
更新日期:2014-12-01 00:00:00
abstract::The authors present a case of permanent atrial standstill with syncopal attacks, in a patient with chronic Chagas' Heart Disease. The recognition of this dysrhythmia was based upon the conventional and intracavity electrocardiographic tracings in addition to phonomecanographic and hemodynamic data. The recording of th...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:
更新日期:1975-01-01 00:00:00
abstract::Electroconvulsive therapy (ECT) is used frequently in psychiatric practice and various electrocardiographic (ECG) changes have been described during ECT. QT dispersion (defined as maximal QT interval minus minimal QT interval) as assessed on the surface electrocardiogram has been demonstrated to reflect regional inhom...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:
更新日期:1998-01-01 00:00:00
abstract::Congenital left ventricular diverticulum is rare and usually isolated or associated with midline thoracoabdominal defects and other congenital cardiac malformations. We describe a case with a previously undescribed malformation syndrome including bilateral obstruction of the ureteropelvic junction, agenesis of corpus ...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.2143/AC.58.3.2005280
更新日期:2003-06-01 00:00:00
abstract::Primary ventricular fibrillation especially occurs during the first hours after acute myocardial infarction and is often not preceded by premonitory ventricular premature beats. In hospital primary ventricular fibrillation can be prevented by an intravenous lidocaine regimen in a rather high dosage. By contrast the ef...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:
更新日期:1977-01-01 00:00:00
abstract:UNLABELLED:The purpose of the study is the predictive value of determination of Tr-T in diagnosis of unstable angina. METHODS:35 pts (24 male, 11 female, mean age 53.4 +/- 5 years) were studied. Group A: 20 pts (15 male, 5 female, mean age 50 +/- 6 years) with unstable angina. Group B: 15 pts (9 male, 6 female, mean a...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:
更新日期:1994-01-01 00:00:00
abstract::Purulent pericarditis is rarely the primary site of bacterial infection. It is usually a complication of an infection originating elsewhere in the body, arising by contiguous spread or haematogenous dissemination.This paper, however, describes a previously healthy young man, who developed a purulent streptococcal peri...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.2143/AC.57.5.2005459
更新日期:2002-10-01 00:00:00
abstract:OBJECTIVE:To test the hypothesis that the circulating white blood cell (WBC) and neutrophil counts are related to left ventricular (LV) indices in patients with the same risk area for acute myocardial infarction (AMI), we examined 100 consecutive AMI patients who had the culprit lesion at segment 6 according to the Ame...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.2143/AC.59.5.2005229
更新日期:2004-10-01 00:00:00
abstract::Atrial bigeminy is a supraventricular arrhythmia rarely associated with severe symptoms. We report the case of a 22-year-old woman with no prior cardiac disease presenting with exercise intolerance since several months. No apparent heart disease other than a spontaneous conducted atrial bigeminy with a short coupling ...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.1080/ac.66.4.2126602
更新日期:2011-08-01 00:00:00
abstract::The effectiveness and safety of intravenous lorcainide was evaluated in 14 patients with normal (QRS less than 110 ms) and in 9 patients with prolonged QRS duration (QRS greater than or equal to 110 ms) showing chronic high frequency premature ventricular complexes (mean value of PVCs 17 min-1). Lorcainide was infused...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:
更新日期:1985-01-01 00:00:00