Remote ischaemic conditioning in patients with ST-elevation myocardial infarction treated with percutaneous coronary intervention: an updated meta-analysis of clinical outcomes.

Abstract:

:Background: All previous meta-analyses including clinical outcomes after remote ischaemic conditioning (RIC) in patients with ST-elevation myocardial infarction (STEMI) treated with percutaneous coronary intervention (PCI) demonstrated that RIC significantly reduced all-cause mortality and major adverse cardiovascular events (MACE). Following the publication of these meta-analyses, three new randomised controlled clinical trials (RCT) including 5712 patients were reported. The objective of this study was to perform an updated meta-analysis about the effectiveness of RIC in reducing MACE in patients with STEMI undergoing PCI.Methods: The search strategy included only RCT identified in MEDLINE, Embase, SCOPUS, and Cochrane (up to February 2020). Eligible studies included any type of RIC. The study adhered to the Preferred Reporting Items of Systematic Reviews and Meta-Analysis (PRISMA) statement. The studies quality was evaluated with Cochrane Risk of Bias tool and Jadad score.Results: Twelve RCT were included in the analysis (Q = 18.8, p = 0.065, I2 = 41.5%, 95%CI 0.0-70.3). Globally, 8239 STEMI patients with 816 MACE were reported with follow-ups between 1 and 45 months. Random effects model showed no significant effect of RIC on composite clinical endpoints (OR = 0.77, 95%CI 0.59-1.01, p = 0.105). Sensitivity analysis demonstrated that only the exclusion of CONDI-2/ERIC PPCI trial modified the significance of the global effect (OR 0.66, 95%CI 0.47-0.93), favouring RIC intervention.Conclusions: The current updated meta-analysis showed that use of RIC around the time of PCI for STEMI treatment added no significant benefit for clinical outcomes assessed between 6 and 45 months after the procedure. These conclusions are in direct contrast to previously published meta-analyses.

journal_name

Acta Cardiol

journal_title

Acta cardiologica

authors

Borracci RA,Amrein E,Alvarez Gallesio JM,Trucksäss S,Higa CC

doi

10.1080/00015385.2020.1766259

subject

Has Abstract

pub_date

2020-07-03 00:00:00

pages

1-9

eissn

0001-5385

issn

1784-973X

pub_type

杂志文章
  • Left ventricular hypertrabeculation/noncompaction as a cardiac manifestation of Duchenne muscular dystrophy under non-invasive positive-pressure ventilation.

    abstract::Though cardiac involvement is a frequent finding in patients with Duchenne muscular dystrophy (DMD) at the wheel-chair-bound stage, left ventricular hypertrabeculation (LVHT) has not been reported. The patient is a 28-year-old male with the typical clinical features of end stage DMD. Since the age of 16 years he requi...

    journal_title:Acta cardiologica

    pub_type: 杂志文章

    doi:10.2143/AC.60.4.2004996

    authors: Finsterer J,Gelpi E,Stöllberger C

    更新日期:2005-08-01 00:00:00

  • Prognostic nutritional index predicts one-year outcome in heart failure with preserved ejection fraction.

    abstract::Background: This study aimed to examine the value of prognostic nutritional index (PNI) as a predictor of outcomes in patients with heart failure and preserved ejection fraction (HFpEF).Methods: We prospectively followed consecutive adult patients admitted to the cardiology outpatient units with HFPEF. Echocardiograph...

    journal_title:Acta cardiologica

    pub_type: 杂志文章

    doi:10.1080/00015385.2019.1661139

    authors: Zencirkiran Agus H,Kahraman S

    更新日期:2020-09-01 00:00:00

  • Influence of percutaneous transcatheter closure of an atrial septal defect on the atrioventricular conduction.

    abstract:OBJECTIVE:This study aimed at determining the effect of percutaneous ASD closure on the AV conduction. Percutaneous closure of ostium secundum atrial septal defects (ASDs) has been widely accepted and has become the standard treatment of this malformation. However, some complications have been reported. Because of the ...

    journal_title:Acta cardiologica

    pub_type: 杂志文章

    doi:10.1080/ac.66.3.2114130

    authors: Cottens D,Van De Bruaene A,Troost E,Willems R,Moons P,Budts W

    更新日期:2011-06-01 00:00:00

  • Aldosterone synthase -344C/T and angiotensin-converting enzyme I/D polymorphisms in Turkish hypertensive patients with normal coronary arteries.

    abstract:BACKGROUND:The renin-angiotensin-aldosterone system (RAAS) plays an important role in blood pressure regulation, left ventricular and vascular structure. Some hypertensive patients develop left ventricular dilatation and heart failure symptoms while others are relatively less affected. The purpose of our study was to d...

    journal_title:Acta cardiologica

    pub_type: 杂志文章

    doi:10.2143/AC.61.1.2005137

    authors: Olcay A,Nisanci Y,Ekmekci CG,Umman B,Bugra Z,Sezer M,Acar RD,Ozbek U

    更新日期:2006-02-01 00:00:00

  • Long-term follow-up of heart transplant patients.

    abstract::The present study was designated to assess long term functional capacity, blood pressure and renal function at 12 and 60 months after heart transplantation. The data of sixty heart transplant recipients were retrospectively reviewed. At rest, radionuclide ejection fraction and cardiac index measured by thermodilution ...

    journal_title:Acta cardiologica

    pub_type: 杂志文章

    doi:

    authors: Baroud I,Niset G,Vachiery JL,Antoine M,Degré S

    更新日期:1996-01-01 00:00:00

  • On the determinants of mortality at the population level.

    abstract::To attain a long and healthy life has always been one of the major goals of humanity. The Chinese emperors, the Egyptian pharaohs and the Aztec kings all aspired to become immortal. To try to avoid mortality and to decrease morbidity at the population level is the role of public health, taken in its broadest sense, in...

    journal_title:Acta cardiologica

    pub_type: 杂志文章

    doi:

    authors: Kesteloot H

    更新日期:1999-06-01 00:00:00

  • Valvular heart disease: plasma B-type natriuretic peptide levels in patients with pure rheumatic mitral stenosis.

    abstract:OBJECTIVE:Our study is designed to evaluate the plasma BNP levels in patients with pure MS and its possible correlation with clinical and echocardiographic parameters of the disease. METHODS AND RESULTS:The study included 29 patients (27 women, 2 men, mean age 43.4 +/- 11.8 y) with pure mitral valve stenosis in sinus ...

    journal_title:Acta cardiologica

    pub_type: 杂志文章

    doi:10.1080/ac.67.1.2146566

    authors: Uçar O,Bayar N,Karagöz A,Aydoğdu S

    更新日期:2012-02-01 00:00:00

  • Mother-offspring aggregation in home versus conventional blood pressure in the Tohoku Study of Child Development (TSCD).

    abstract:OBJECTIVE:Few studies described the home blood pressure (HBP) in young children. Using intrafamilial correlations of blood pressure as research focus, we assessed the feasibility of HBP monitoring in this age group. METHODS:We enrolled 382 mothers (mean age 38.8 years) and singletons (7.0 years) in theTohoku Study of ...

    journal_title:Acta cardiologica

    pub_type: 杂志文章

    doi:10.1080/ac.67.4.2170687

    authors: Asayama K,Staessen JA,Hayashi K,Hosaka M,Tatsuta N,Kurokawa N,Satoh M,Hashimoto T,Hirose T,Obara T,Metoki H,Inoue R,Kikuya M,Ohkubo T,Nakai K,Imai Y,Satoh H

    更新日期:2012-08-01 00:00:00

  • Age-related changes in myocardial nerve and collagen networks of the auricle of the right atrium.

    abstract:OBJECTIVE:The objective of this study was to analyse age-related changes in human myocardial nerve plexuses and collagen networks of the auricle of the right atrium in subjects in whom no cardiac diseases or pathology had been diagnosed. METHODS AND RESULTS:Morphometric analysis of acetylcholinesterase (AChE)-stained ...

    journal_title:Acta cardiologica

    pub_type: 杂志文章

    doi:10.2143/AC.61.5.2017765

    authors: Burkauskiene A,Mackiewicz Z,Virtanen I,Konttinen YT

    更新日期:2006-10-01 00:00:00

  • Pilot project for registering acute myocardial infarctions in Belgium.

    abstract::In order to prepare Belgian participation in the International Study "Monitoring of trends and determinants in cardiovascular disease (MONICA)", a pilot project for registration of acute myocardial infarctions was organized in the Flemish city of Ghent and the Walloon city of Charleroi. Thanks to the collaboration of ...

    journal_title:Acta cardiologica

    pub_type: 杂志文章

    doi:

    authors: Berghmans L,Heyerick P,De Backer G,Kornitzer M,Fux M

    更新日期:1985-01-01 00:00:00

  • Does resting echocardiography predict a positive response to subsequent low-dose dobutamine stress echocardiography in patients with ischaemic cardiomyopathy?

    abstract:OBJECTIVE:dobutamine stress echocardiography (DSE) in patients with ischaemic cardiomyopathy. We explored the accuracy of resting echocardiographic and tissue Doppler parameters to predict a positive response by low-dose METHODS AND RESULTS:We enrolled 100 consecutive patients with prior myocardial infarction, and a l...

    journal_title:Acta cardiologica

    pub_type: 杂志文章

    doi:10.1080/ac.67.6.2184672

    authors: Abdel-Salam Z,Nammas W

    更新日期:2012-12-01 00:00:00

  • Acute pericarditis induced stress cardiomyopathy.

    abstract::A 67-year-old Caucasian woman presented with chest pain suggestive of acute pericarditis. On initial evaluation the apical ballooning variant of stress-related cardiomyopathy (CMP) was present. The stress CMP and acute pericarditis resolved within a week. The patient returned in four weeks with early cardiac tamponade...

    journal_title:Acta cardiologica

    pub_type: 杂志文章

    doi:10.2143/AC.65.3.2050358

    authors: Li JW,Nanda S,Longo S

    更新日期:2010-06-01 00:00:00

  • Haemodynamic alterations of the left ventricle during right atrial pacing.

    abstract::The left ventricular haemodynamic alterations during right atrial pacing were studied in 12 cases. Cardiac index varied little: during maximal rate however, its mean value was slightly lower than the resting one. Stroke index decreased inversely to the heart rate. The course of these indices did not separate the norma...

    journal_title:Acta cardiologica

    pub_type: 杂志文章

    doi:

    authors: Kolettis M,Gialafos J,Toutouzas P,Avgoustakis D

    更新日期:1976-01-01 00:00:00

  • Chest pain with less than 20% change in high sensitivity troponin T - a low risk cohort?

    abstract::Background: Patients with chest pain are risk-stratified using serial high-sensitivity troponin (T) assays (hsTnT). Those with change in (Δ)hsTnT <20% are often categorised as low-risk and are less likely to be managed as acute coronary syndromes (ACS). We sought to characterise such a population of 'low-risk' chest p...

    journal_title:Acta cardiologica

    pub_type: 杂志文章

    doi:10.1080/00015385.2018.1561598

    authors: Weir RAP,Osmanska J,Docherty KF,Petrie CJ

    更新日期:2020-04-01 00:00:00

  • The balance of omega-3 polyunsaturated fatty acids for -reducing residual risks in patients with coronary artery disease.

    abstract::Residual risk, which cannot be prevented by statins alone, must be controlled for inhibiting the onset of coronary events. Omega-3 polyunsaturated fatty acids (PUFAs) play an important role in controlling residual risk. The Japan eicosapentaenoic acid (EPA) Lipid Intervention Study demonstrated the inhibitory effect o...

    journal_title:Acta cardiologica

    pub_type: 杂志文章,评审

    doi:10.1080/00015385.2017.1305174

    authors: Nishizaki Y,Shimada K,Daida H

    更新日期:2017-06-01 00:00:00

  • Prognostic value of carbohydrate antigen 125 combined with N-terminal pro B-type natriuretic peptide in patients with acute heart failure.

    abstract::Background: The objective was to explore the value of serum carbohydrate antigen 125 (CA125) combined with N-terminal pro B-type natriuretic peptide (NT-proBNP) in predicting the clinical prognosis of patients with acute heart failure (AHF).Methods: We prospectively observed 213 patients with AHF. CA125 (U/ml) and NT-...

    journal_title:Acta cardiologica

    pub_type: 杂志文章

    doi:10.1080/00015385.2020.1769347

    authors: Chen X,Wu M,Xu K,Huang M,Zhuo X

    更新日期:2020-06-10 00:00:00

  • Compartments and suborgans of the ventricular myocardium.

    abstract::Color-coded liquid plastic was injected intraparenchymally (not into the blood vessels) into more than 300 hearts of homeotherms--including dog, cat, sheep, beef, horse, mammalian dolphins, chickens, turkeys, etc. The organization of the hearts of all these species appears to be similar. After injection of a heart seg...

    journal_title:Acta cardiologica

    pub_type: 杂志文章

    doi:

    authors: Rodbard S

    更新日期:1976-01-01 00:00:00

  • Treatment patterns in anticoagulant therapy in patients with newly diagnosed atrial fibrillation in Belgium: results from the GARFIELD-AF registry.

    abstract::Background: AF, anticoagulation, NOACs, changing patterns of prescription. Methods: We describe baseline data and treatment patterns of patients recruited in Belgium in the Global Anticoagulant Registry in the FIELD-Atrial Fibrillation (GARFIELD-AF). Recruitment began when novel oral anticoagulants (NOACs) were introd...

    journal_title:Acta cardiologica

    pub_type: 杂志文章,多中心研究

    doi:10.1080/00015385.2018.1494089

    authors: Cools F,Wollaert B,Vervoort G,Verstraete S,Voet J,Hermans K,Heyse A,De Wolf A,Hollanders G,Boussy T,Anné W,Vercammen J,Faes D,Beutels M,Mairesse G,Purnode P,Blankoff I,Vandergoten P,Capiau L,Allu J,Bassand JP,Ka

    更新日期:2019-08-01 00:00:00

  • Suprarenal aortic aneurysm closure with an atrial septal defect Amplatzer device.

    abstract::Conventional repair of pararenal aortic aneurysms has been a technically challenging operation, with a significant morbidity rate of 28-35%. Endovascular stent grafting requires satisfactory landing zones for stent graft anchoring. Therefore, pararenal abdominal aortic aneurysms are usually contraindicated for this pr...

    journal_title:Acta cardiologica

    pub_type: 杂志文章

    doi:10.1080/ac.69.4.3036661

    authors: Sokhanvar S,Ahmadiyeh A,Golmohamadi Z

    更新日期:2014-08-01 00:00:00

  • Myocardial damage after D.C. countershock: myoglobin and CK-MB radioimmunoassay evaluation.

    abstract::After D.C. countershock to terminate cardiac arrhythmias, in 3 out of 8 patients studied, an increase in both plasma myoglobin (Mb) and CK-MB (assessed by radioimmunoassay) was found. In 2 patients there was an increase of only plasma Mb and in 1 an increase of only CK-MB. In 2 cases no increase of either parameters w...

    journal_title:Acta cardiologica

    pub_type: 杂志文章

    doi:

    authors: Pauletto P,Scannapieco G,Compostella L,Maddalena F,Dario C,Pessina AC,Dal Palù C

    更新日期:1984-01-01 00:00:00

  • QTc-measurements: a case-control study on serum electrolytes.

    abstract::This is a report on a prospective case-control study, in which a group of patients with an electrocardiographic diagnosis of QTc-prolongation (cases) was compared with a group of patients with a normal QTc (controls) for the presence of potential causative factors. Twelve cases and twelve carefully-matched controls we...

    journal_title:Acta cardiologica

    pub_type: 杂志文章

    doi:

    authors: Vervaet P,Amery W

    更新日期:1993-01-01 00:00:00

  • Chronic mitral regurgitation--significance of the echocardiographic determinants in predicting severity.

    abstract:UNLABELLED:The aim of study was to determine the significance of the best echocardiographic parameters for assessing the severity of mitral regurgitation (MR). METHODS:The study population consisted of 107 patients, mean age 52 +/- 7 y with chronic isolated non-ischaemic MR. Quantification of the MR was performed usin...

    journal_title:Acta cardiologica

    pub_type: 杂志文章

    doi:10.2143/AC.64.2.2036136

    authors: Leśniak-Sobelga A,Kostkiewicz M,Olszowska M,Pieniazek P,Tracz W

    更新日期:2009-04-01 00:00:00

  • Diffuse intra-alveolar haemorrhage as a complication of thrombolytic therapy in acute myocardial infarction.

    abstract::Diffuse intra-alveolar haemorrhage is a rare complication of thrombolytic therapy (TT). We report a patient who developed haemoptysis due to pulmonary haemorrhage. This diagnosis should be considered in any patients with respiratory distress, diffuse pulmonary infiltrates, and haemoptysis and otherwise unexplained dec...

    journal_title:Acta cardiologica

    pub_type: 杂志文章

    doi:10.2143/AC.59.3.2005194

    authors: Baran I,Ozdemir B,Coşkun S

    更新日期:2004-06-01 00:00:00

  • Left systolic atrioventricular plane displacement in the assessment of myocardial viability in patients with previous myocardial infarction.

    abstract:UNLABELLED:In order to detect myocardial viability in coronary artery disease patients (CAD) with a previous myocardial infarction and dysfunction of the left ventricle (LV), the reliability of the left atrioventricular plane displacement (LAVPD) during low dose dobutamine stress echocardiography (DSE), was validated. ...

    journal_title:Acta cardiologica

    pub_type: 杂志文章

    doi:

    authors: Bouki K,Kranidis A,Kostopoulos K,Rondogianni F,Giannopoulou H,Antonelis J,Fehske W,Tavernarakis A,Kesse M,Anthopoulos L

    更新日期:1995-01-01 00:00:00

  • [Arterial vascularization of the sino-auricular node of the heart in dogs].

    abstract::In order to study the arterial blood supply of the sinus atrial node in the Dog, the authors have performed the post-mortem injection of the arterial branches going to this node. They observed 65 cases and they came to the following conclusions: in 31 cases (47.7%) the sinus atrial node is supplied by the artery of th...

    journal_title:Acta cardiologica

    pub_type: 杂志文章

    doi:

    authors: Pina JA,Pereira AT,Ferreira Ados S

    更新日期:1975-01-01 00:00:00

  • Combined "pro-atherosclerotic" variants of the ACE and APOE genes increase the risk of the coronary artery disease associated with the presence of cigarette smoking.

    abstract:OBJECTIVE:Cigarette smoking increases the synthesis of angiotensin-1 converting enzyme (ACE) and induces oxidative modifications of the apolipoprotein E (apo E).Thus we explored the gene-environment interactions between APOE gene epsilon and ACE gene insertion/deletion polymorphisms and cigarette smoking in coronary ar...

    journal_title:Acta cardiologica

    pub_type: 杂志文章

    doi:10.2143/AC.63.6.2033392

    authors: Zak I,Niemiec P,Balcerzyk A,Krauze J

    更新日期:2008-12-01 00:00:00

  • A study of orifice shape effects in the determination of mitral valve area by two-dimensional echocardiography.

    abstract::Real-time two-dimensional echocardiographic studies of the mitral valve in short-axis view were obtained from 10 normal subjects. Stop-action frames of the video-taped echocardiograms were then photographed to obtain diastolic cross-sectional images of the valve at maximal opening. Tracings from the interior of the le...

    journal_title:Acta cardiologica

    pub_type: 杂志文章

    doi:

    authors: Hearn TC,Goldblatt E,Mazumdar J,Fazzalari NL,Nandagopal D

    更新日期:1983-01-01 00:00:00

  • Hemodynamic effects of nifedipine in patients with asymptomatic aortic regurgitation: evaluation by Doppler echocardiography.

    abstract::Nineteen asymptomatic patients affected by isolated chronic aortic regurgitation received 20 mg of nifedipine sublingually: the acute hemodynamic effects of nifedipine were evaluated by combined cross-sectional and Doppler echocardiography. To assess variations in the regurgitant flow volume, the flow volume across th...

    journal_title:Acta cardiologica

    pub_type: 杂志文章

    doi:

    authors: Gentile F,Ornaghi M,Esposti D,Triulzi MO

    更新日期:1993-01-01 00:00:00

  • Aberrant right coronary artery arising from the left sinus of Valsalva with an interarterial course.

    abstract::An anomalous origin of the right coronary artery from the left sinus of Valsalva with an interarterial course is a rather rare congenital anomaly. Treatment strategies are determined by the risk of sudden cardiac death and the presence of cardiac ischaemia. We present two cases of middle-aged patients who were diagnos...

    journal_title:Acta cardiologica

    pub_type: 杂志文章

    doi:10.1080/ac.69.2.3017300

    authors: De Pooter J,Van Driessche L,Bartunek J

    更新日期:2014-04-01 00:00:00

  • Subclinical arterial wall damage in patients at low to moderate cardiovascular risk.

    abstract:AIM:The aim of this paper is to study the degree of subclinical arterial wall damage in subjects at low and moderate risk of cardiovascular death by the SCORE scale using instrumental research methods. METHODS:We enrolled 600 patients (mean age 49.0 +/- 7.1 years, 74% women) with a calculated SCORE 5%, who passed a ca...

    journal_title:Acta cardiologica

    pub_type: 杂志文章

    doi:10.1080/ac.70.3.3080631

    authors: Boytcov SA,Urazalina SJ,Kukharchuk VV,Balakhonova TV,Sergienko IV

    更新日期:2015-06-01 00:00:00