Abstract:
:Background: All previous meta-analyses including clinical outcomes after remote ischaemic conditioning (RIC) in patients with ST-elevation myocardial infarction (STEMI) treated with percutaneous coronary intervention (PCI) demonstrated that RIC significantly reduced all-cause mortality and major adverse cardiovascular events (MACE). Following the publication of these meta-analyses, three new randomised controlled clinical trials (RCT) including 5712 patients were reported. The objective of this study was to perform an updated meta-analysis about the effectiveness of RIC in reducing MACE in patients with STEMI undergoing PCI.Methods: The search strategy included only RCT identified in MEDLINE, Embase, SCOPUS, and Cochrane (up to February 2020). Eligible studies included any type of RIC. The study adhered to the Preferred Reporting Items of Systematic Reviews and Meta-Analysis (PRISMA) statement. The studies quality was evaluated with Cochrane Risk of Bias tool and Jadad score.Results: Twelve RCT were included in the analysis (Q = 18.8, p = 0.065, I2 = 41.5%, 95%CI 0.0-70.3). Globally, 8239 STEMI patients with 816 MACE were reported with follow-ups between 1 and 45 months. Random effects model showed no significant effect of RIC on composite clinical endpoints (OR = 0.77, 95%CI 0.59-1.01, p = 0.105). Sensitivity analysis demonstrated that only the exclusion of CONDI-2/ERIC PPCI trial modified the significance of the global effect (OR 0.66, 95%CI 0.47-0.93), favouring RIC intervention.Conclusions: The current updated meta-analysis showed that use of RIC around the time of PCI for STEMI treatment added no significant benefit for clinical outcomes assessed between 6 and 45 months after the procedure. These conclusions are in direct contrast to previously published meta-analyses.
journal_name
Acta Cardioljournal_title
Acta cardiologicaauthors
Borracci RA,Amrein E,Alvarez Gallesio JM,Trucksäss S,Higa CCdoi
10.1080/00015385.2020.1766259subject
Has Abstractpub_date
2020-07-03 00:00:00pages
1-9eissn
0001-5385issn
1784-973Xpub_type
杂志文章abstract::Though cardiac involvement is a frequent finding in patients with Duchenne muscular dystrophy (DMD) at the wheel-chair-bound stage, left ventricular hypertrabeculation (LVHT) has not been reported. The patient is a 28-year-old male with the typical clinical features of end stage DMD. Since the age of 16 years he requi...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.2143/AC.60.4.2004996
更新日期:2005-08-01 00:00:00
abstract::Background: This study aimed to examine the value of prognostic nutritional index (PNI) as a predictor of outcomes in patients with heart failure and preserved ejection fraction (HFpEF).Methods: We prospectively followed consecutive adult patients admitted to the cardiology outpatient units with HFPEF. Echocardiograph...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.1080/00015385.2019.1661139
更新日期:2020-09-01 00:00:00
abstract:OBJECTIVE:This study aimed at determining the effect of percutaneous ASD closure on the AV conduction. Percutaneous closure of ostium secundum atrial septal defects (ASDs) has been widely accepted and has become the standard treatment of this malformation. However, some complications have been reported. Because of the ...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.1080/ac.66.3.2114130
更新日期:2011-06-01 00:00:00
abstract:BACKGROUND:The renin-angiotensin-aldosterone system (RAAS) plays an important role in blood pressure regulation, left ventricular and vascular structure. Some hypertensive patients develop left ventricular dilatation and heart failure symptoms while others are relatively less affected. The purpose of our study was to d...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.2143/AC.61.1.2005137
更新日期:2006-02-01 00:00:00
abstract::The present study was designated to assess long term functional capacity, blood pressure and renal function at 12 and 60 months after heart transplantation. The data of sixty heart transplant recipients were retrospectively reviewed. At rest, radionuclide ejection fraction and cardiac index measured by thermodilution ...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:
更新日期:1996-01-01 00:00:00
abstract::To attain a long and healthy life has always been one of the major goals of humanity. The Chinese emperors, the Egyptian pharaohs and the Aztec kings all aspired to become immortal. To try to avoid mortality and to decrease morbidity at the population level is the role of public health, taken in its broadest sense, in...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:
更新日期:1999-06-01 00:00:00
abstract:OBJECTIVE:Our study is designed to evaluate the plasma BNP levels in patients with pure MS and its possible correlation with clinical and echocardiographic parameters of the disease. METHODS AND RESULTS:The study included 29 patients (27 women, 2 men, mean age 43.4 +/- 11.8 y) with pure mitral valve stenosis in sinus ...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.1080/ac.67.1.2146566
更新日期:2012-02-01 00:00:00
abstract:OBJECTIVE:Few studies described the home blood pressure (HBP) in young children. Using intrafamilial correlations of blood pressure as research focus, we assessed the feasibility of HBP monitoring in this age group. METHODS:We enrolled 382 mothers (mean age 38.8 years) and singletons (7.0 years) in theTohoku Study of ...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.1080/ac.67.4.2170687
更新日期:2012-08-01 00:00:00
abstract:OBJECTIVE:The objective of this study was to analyse age-related changes in human myocardial nerve plexuses and collagen networks of the auricle of the right atrium in subjects in whom no cardiac diseases or pathology had been diagnosed. METHODS AND RESULTS:Morphometric analysis of acetylcholinesterase (AChE)-stained ...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.2143/AC.61.5.2017765
更新日期:2006-10-01 00:00:00
abstract::In order to prepare Belgian participation in the International Study "Monitoring of trends and determinants in cardiovascular disease (MONICA)", a pilot project for registration of acute myocardial infarctions was organized in the Flemish city of Ghent and the Walloon city of Charleroi. Thanks to the collaboration of ...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:
更新日期:1985-01-01 00:00:00
abstract:OBJECTIVE:dobutamine stress echocardiography (DSE) in patients with ischaemic cardiomyopathy. We explored the accuracy of resting echocardiographic and tissue Doppler parameters to predict a positive response by low-dose METHODS AND RESULTS:We enrolled 100 consecutive patients with prior myocardial infarction, and a l...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.1080/ac.67.6.2184672
更新日期:2012-12-01 00:00:00
abstract::A 67-year-old Caucasian woman presented with chest pain suggestive of acute pericarditis. On initial evaluation the apical ballooning variant of stress-related cardiomyopathy (CMP) was present. The stress CMP and acute pericarditis resolved within a week. The patient returned in four weeks with early cardiac tamponade...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.2143/AC.65.3.2050358
更新日期:2010-06-01 00:00:00
abstract::The left ventricular haemodynamic alterations during right atrial pacing were studied in 12 cases. Cardiac index varied little: during maximal rate however, its mean value was slightly lower than the resting one. Stroke index decreased inversely to the heart rate. The course of these indices did not separate the norma...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:
更新日期:1976-01-01 00:00:00
abstract::Background: Patients with chest pain are risk-stratified using serial high-sensitivity troponin (T) assays (hsTnT). Those with change in (Δ)hsTnT <20% are often categorised as low-risk and are less likely to be managed as acute coronary syndromes (ACS). We sought to characterise such a population of 'low-risk' chest p...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.1080/00015385.2018.1561598
更新日期:2020-04-01 00:00:00
abstract::Residual risk, which cannot be prevented by statins alone, must be controlled for inhibiting the onset of coronary events. Omega-3 polyunsaturated fatty acids (PUFAs) play an important role in controlling residual risk. The Japan eicosapentaenoic acid (EPA) Lipid Intervention Study demonstrated the inhibitory effect o...
journal_title:Acta cardiologica
pub_type: 杂志文章,评审
doi:10.1080/00015385.2017.1305174
更新日期:2017-06-01 00:00:00
abstract::Background: The objective was to explore the value of serum carbohydrate antigen 125 (CA125) combined with N-terminal pro B-type natriuretic peptide (NT-proBNP) in predicting the clinical prognosis of patients with acute heart failure (AHF).Methods: We prospectively observed 213 patients with AHF. CA125 (U/ml) and NT-...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.1080/00015385.2020.1769347
更新日期:2020-06-10 00:00:00
abstract::Color-coded liquid plastic was injected intraparenchymally (not into the blood vessels) into more than 300 hearts of homeotherms--including dog, cat, sheep, beef, horse, mammalian dolphins, chickens, turkeys, etc. The organization of the hearts of all these species appears to be similar. After injection of a heart seg...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:
更新日期:1976-01-01 00:00:00
abstract::Background: AF, anticoagulation, NOACs, changing patterns of prescription. Methods: We describe baseline data and treatment patterns of patients recruited in Belgium in the Global Anticoagulant Registry in the FIELD-Atrial Fibrillation (GARFIELD-AF). Recruitment began when novel oral anticoagulants (NOACs) were introd...
journal_title:Acta cardiologica
pub_type: 杂志文章,多中心研究
doi:10.1080/00015385.2018.1494089
更新日期:2019-08-01 00:00:00
abstract::Conventional repair of pararenal aortic aneurysms has been a technically challenging operation, with a significant morbidity rate of 28-35%. Endovascular stent grafting requires satisfactory landing zones for stent graft anchoring. Therefore, pararenal abdominal aortic aneurysms are usually contraindicated for this pr...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.1080/ac.69.4.3036661
更新日期:2014-08-01 00:00:00
abstract::After D.C. countershock to terminate cardiac arrhythmias, in 3 out of 8 patients studied, an increase in both plasma myoglobin (Mb) and CK-MB (assessed by radioimmunoassay) was found. In 2 patients there was an increase of only plasma Mb and in 1 an increase of only CK-MB. In 2 cases no increase of either parameters w...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:
更新日期:1984-01-01 00:00:00
abstract::This is a report on a prospective case-control study, in which a group of patients with an electrocardiographic diagnosis of QTc-prolongation (cases) was compared with a group of patients with a normal QTc (controls) for the presence of potential causative factors. Twelve cases and twelve carefully-matched controls we...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:
更新日期:1993-01-01 00:00:00
abstract:UNLABELLED:The aim of study was to determine the significance of the best echocardiographic parameters for assessing the severity of mitral regurgitation (MR). METHODS:The study population consisted of 107 patients, mean age 52 +/- 7 y with chronic isolated non-ischaemic MR. Quantification of the MR was performed usin...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.2143/AC.64.2.2036136
更新日期:2009-04-01 00:00:00
abstract::Diffuse intra-alveolar haemorrhage is a rare complication of thrombolytic therapy (TT). We report a patient who developed haemoptysis due to pulmonary haemorrhage. This diagnosis should be considered in any patients with respiratory distress, diffuse pulmonary infiltrates, and haemoptysis and otherwise unexplained dec...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.2143/AC.59.3.2005194
更新日期:2004-06-01 00:00:00
abstract:UNLABELLED:In order to detect myocardial viability in coronary artery disease patients (CAD) with a previous myocardial infarction and dysfunction of the left ventricle (LV), the reliability of the left atrioventricular plane displacement (LAVPD) during low dose dobutamine stress echocardiography (DSE), was validated. ...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:
更新日期:1995-01-01 00:00:00
abstract::In order to study the arterial blood supply of the sinus atrial node in the Dog, the authors have performed the post-mortem injection of the arterial branches going to this node. They observed 65 cases and they came to the following conclusions: in 31 cases (47.7%) the sinus atrial node is supplied by the artery of th...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:
更新日期:1975-01-01 00:00:00
abstract:OBJECTIVE:Cigarette smoking increases the synthesis of angiotensin-1 converting enzyme (ACE) and induces oxidative modifications of the apolipoprotein E (apo E).Thus we explored the gene-environment interactions between APOE gene epsilon and ACE gene insertion/deletion polymorphisms and cigarette smoking in coronary ar...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.2143/AC.63.6.2033392
更新日期:2008-12-01 00:00:00
abstract::Real-time two-dimensional echocardiographic studies of the mitral valve in short-axis view were obtained from 10 normal subjects. Stop-action frames of the video-taped echocardiograms were then photographed to obtain diastolic cross-sectional images of the valve at maximal opening. Tracings from the interior of the le...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:
更新日期:1983-01-01 00:00:00
abstract::Nineteen asymptomatic patients affected by isolated chronic aortic regurgitation received 20 mg of nifedipine sublingually: the acute hemodynamic effects of nifedipine were evaluated by combined cross-sectional and Doppler echocardiography. To assess variations in the regurgitant flow volume, the flow volume across th...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:
更新日期:1993-01-01 00:00:00
abstract::An anomalous origin of the right coronary artery from the left sinus of Valsalva with an interarterial course is a rather rare congenital anomaly. Treatment strategies are determined by the risk of sudden cardiac death and the presence of cardiac ischaemia. We present two cases of middle-aged patients who were diagnos...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.1080/ac.69.2.3017300
更新日期:2014-04-01 00:00:00
abstract:AIM:The aim of this paper is to study the degree of subclinical arterial wall damage in subjects at low and moderate risk of cardiovascular death by the SCORE scale using instrumental research methods. METHODS:We enrolled 600 patients (mean age 49.0 +/- 7.1 years, 74% women) with a calculated SCORE 5%, who passed a ca...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.1080/ac.70.3.3080631
更新日期:2015-06-01 00:00:00