Abstract:
OBJECTIVE:Our study is designed to evaluate the plasma BNP levels in patients with pure MS and its possible correlation with clinical and echocardiographic parameters of the disease. METHODS AND RESULTS:The study included 29 patients (27 women, 2 men, mean age 43.4 +/- 11.8 y) with pure mitral valve stenosis in sinus rhythm and 24 age- and gender-matched healthy voluteers (17 women, 7 men, mean age 42 +/- 13 y). Plasma BNP levels were significantly higher in the mitral stenosis group compared to controls (91.1 +/- 69.6 pg/ml vs. 14.4 +/- 9.2 pg/ml, P < 0.0001). In univariate analysis, plasma BNP levels correlated positively with left ventricular end-systolic diameter (r = 0.439, P = 0.041), left atrial diameter (r = 0.772, P < 0.001), peak diastolic transmitral gradient (r = 0.621, P = 0.003), mean diastolic transmitral gradient (r = 0.751, P < 0.001), peak systolic pulmonary artery pressure (r = 0.467, P = 0.044), functional capacity (r = 0.819, P < 0.001) and negatively with left ventricular ejection fraction (r = -0.482, P = 0.020) and planimetric mitral valve area (r = -0.494, P = 0.006). No significant correlation existed between age, end-diastolic diameter and right ventricular diameter (r = 0.185, P = 0.337; r = 0.227, P = 0.309; r = 0.319, P = 0.092; respectively). A receiver operating characteristic (ROC) curve identified a BNP value of 32 pg/ml as the best cut-off for the identification of patients with mitral stenosis with a positive predictive value of 100% and a negative predictive value of 75%. CONCLUSIONS:In this study we found elevated plasma BNP levels in patients with pure MS in sinus rhythm. Plasma BNP levels correlated with disease severity and this can have potential clinical implications, for example in patients undergoing percutaneous balloon mitral valvuloplasty or in patients with poor echocardiographic windows.
journal_name
Acta Cardioljournal_title
Acta cardiologicaauthors
Uçar O,Bayar N,Karagöz A,Aydoğdu Sdoi
10.1080/ac.67.1.2146566subject
Has Abstractpub_date
2012-02-01 00:00:00pages
59-64issue
1eissn
0001-5385issn
1784-973Xjournal_volume
67pub_type
杂志文章abstract:OBJECTIVE:The beneficial effect of pentoxifylline (PTX) on ischaemic-reperfusion injury was assessed in a rat model of transient global cerebral ischaemia. DESIGN:Randomized, controlled, prospective study. SETTING:University research laboratory. SUBJECTS:Thirty-six male Wistar albino rats. INTERVENTIONS:Ischaemia w...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:
更新日期:1998-01-01 00:00:00
abstract::The clinical, hemodynamic findings and surgical results of forty patients with rheumatic tricuspid stenosis are presented. It is concluded that tricuspid stenosis is a frequent lesion. Its signs should be sought carefully and documented by simultaneous measurements of the right ventricular diastolic and right atrial p...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:
更新日期:1978-01-01 00:00:00
abstract::In chronic aorto-iliac occlusive disease, pre-existing renal artery stenosis may give rise to sufficient development of collateral blood flow and prevent ischaemic symptoms for a long time and therefore may cause delay in diagnosis. An early diagnosis of aorto-iliac disease is necessary in order to avoid fatal outcome...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.2143/AC.64.3.2038035
更新日期:2009-06-01 00:00:00
abstract:OBJECTIVE:Red cell distribution width (RDW) is a measure of variation in the volume of circulating erythrocytes and has recently emerged as a powerful prognostic marker in heart failure. We studied the effect of 5-month, home-based cardiac rehabilitation on RDW. METHODS AND RESULTS:Sixty-two patients (age: median 67 y...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.1080/ac.68.6.8000009
更新日期:2013-12-01 00:00:00
abstract:OBJECTIVE:Decreased effects of smoking on serum high-density lipoprotein cholesterol (HDL-c) were demonstrated in subjects smoking more than 20 cigarettes a day. We aimed to evaluate the effects of non-heavy smoking (< or =20 cigarettes a day) on HDL-c in young, healthy men who are similar in terms of age, physical act...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.2143/AC.61.4.2017301
更新日期:2006-08-01 00:00:00
abstract:OBJECTIVE:The purpose of this study was to examine the practice of cardiac bradycardia pacing in an electrophysiology laboratory and to evaluate the safety and efficacy of pacemaker implantation by cardiologists in this setting. METHODS AND RESULTS:We evaluated a consecutive series of the first 500 permanent pacemaker...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:
更新日期:1999-12-01 00:00:00
abstract:OBJECTIVES:The objective of this study is to evaluate the prevalence of HR2 polymorphism among patients with pulmonary embolism (PE) and healthy subjects. BACKGROUND:Polymorphism in the factor V gene named HR2 has been described as a possible risk factor for venous thromboembolism (VTE) development. Contradictive resu...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.2143/AC.70.6.3120184
更新日期:2015-12-01 00:00:00
abstract::A 67-year-old Caucasian woman presented with chest pain suggestive of acute pericarditis. On initial evaluation the apical ballooning variant of stress-related cardiomyopathy (CMP) was present. The stress CMP and acute pericarditis resolved within a week. The patient returned in four weeks with early cardiac tamponade...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.2143/AC.65.3.2050358
更新日期:2010-06-01 00:00:00
abstract::Between April 1988 and October 1989, 22 adult patients with isolated or predominant severe mitral stenosis underwent Percutaneous Transvenous Mitral Valvuloplasty (PTMV). In 20 patients, a transseptal double balloon technique was used; in the last 2 patients, dilatation was performed using the Inoué balloon. Immediate...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:
更新日期:1990-01-01 00:00:00
abstract:OBJECTIVES:Large pericardial effusions and cardiac tamponade are rare in childhood. The aim of this study was to evaluate the aetiological factors and clinical findings of large pericardial effusion and cardiac tamponade in children. METHODS:We reviewed retrospectively the records of 10 (6 male, 4 female) patients (me...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.2143/AC.62.2.2020232
更新日期:2007-04-01 00:00:00
abstract:OBJECTIVE:Mild reductions in iodine concentration could reduce acute side effects after intraarterial contrast media administration without affecting the quality of coronary artery images. This study was designed to show the equivalence in terms of image quality of two nonionic low-osmolar monomers, iobitridol 350 and ...
journal_title:Acta cardiologica
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.2143/AC.65.4.2053896
更新日期:2010-08-01 00:00:00
abstract:OBJECTIVE:This study sought to compare characteristics and management of myocardial infarction in men and women, and whether a difference in management would translate into a difference in in-hospital mortality. METHODS AND RESULTS:Data were prospectively collected in 2,519 patients (801 women) admitted in all hospita...
journal_title:Acta cardiologica
pub_type: 杂志文章,多中心研究
doi:10.2143/AC.56.3.2005637
更新日期:2001-06-01 00:00:00
abstract:BACKGROUND:Familial hypercholesterolaemia (FH) is underdiagnosed in most countries. We report our first experience from a national pilot project of cascade screening in relatives of FH patients. METHODOLOGY:Participating specialists recruited consecutive index patients (IP) with Dutch Lipid Clinic Network (DLCN) score...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.1080/00015385.2020.1820683
更新日期:2020-09-23 00:00:00
abstract:AIMS:We retrospectively followed 250 patients who started dialysis between 2005 and 2009 to clarify the prevalence, the prognosis and the prescribed heart failure treatment of systolic heart failure patients on dialysis. METHODS AND RESULTS:This cohort was divided according to left ventricular ejection fraction (LVEF)...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.1080/ac.68.1.2959632
更新日期:2013-02-01 00:00:00
abstract::The modifications that atrial flutter determines on the phonocardiogram, apexcardiogram, carotid pulse tracing, jugular venous pulse tracing, and indirect (esophageal) left atrial pulse tracing were studied. On the basis of the data here presented and that of the literature, a polygraphic profile of atrial flutter has...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:
更新日期:1976-01-01 00:00:00
abstract::The optimal management of high-risk patients requiring urgent or emergency noncardiac surgery when the options for further testing and evaluation are limited, is unclear. The focus of most of the literature, including the American College of Cardiology/American Heart Association guidelines, has been on patients underg...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.2143/AC.60.5.2004980
更新日期:2005-10-01 00:00:00
abstract::Background: Cardiovascular rehabilitation and retraining seek to increase cardiorespiratory fitness and to manage certain risk factors such as smoking, hypercholesterolaemia and sedentary lifestyle. Such lifestyle changes can be influenced by a combination of health determinants. Aim: The purpose of this study is to a...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.1080/00015385.2019.1639269
更新日期:2019-07-17 00:00:00
abstract::Background: Atrial fibrillation (AF) is related to an increased stroke risk. At present, differentiation between patients with paroxysmal AF (pAF) and without is only possible during AF episodes and not during sinus rhythm. If AF could be diagnosed more quickly and reliably, anticoagulation therapy may be administered...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.1080/00015385.2018.1493248
更新日期:2019-08-01 00:00:00
abstract::The Cardiology Foundation supported by the perspicacious Princess Lilian was created in 1958. As an introduction to this symposium, the challenges that the cardiologist and surgeon encountered in 1958, are recalled as well as the essential problems requiring solutions in that era of evolving cardiac surgery. ...
journal_title:Acta cardiologica
pub_type: 历史文章,杂志文章
doi:
更新日期:2004-01-01 00:00:00
abstract:UNLABELLED:The aim of study was to determine the significance of the best echocardiographic parameters for assessing the severity of mitral regurgitation (MR). METHODS:The study population consisted of 107 patients, mean age 52 +/- 7 y with chronic isolated non-ischaemic MR. Quantification of the MR was performed usin...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.2143/AC.64.2.2036136
更新日期:2009-04-01 00:00:00
abstract::Atherosclerotic involvement of extracoronary arteries in patients undergoing myocardial revascularization can cause severe postoperative complications and increase postoperative mortality. Between January and November 1998, routine preoperative echo-Doppler study of carotid vessels, abdominal aorta and iliac-femoral a...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.2143/AC.56.2.2005623
更新日期:2001-04-01 00:00:00
abstract:OBJECTIVE:The European Society of Cardiology designated 2008 as the year of imaging. However, despite the intense focus on the many types of imaging and the relative benefits of each one, the optimal modalityfor the diagnosis of coronary artery disease remains controversial. Among the currently available techniques, co...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.1080/ac.66.2.2071253
更新日期:2011-04-01 00:00:00
abstract:OBJECTIVES:Angiotensin-converting enzyme (ACE) is a key enzyme in the production of angiotensin II and thus may participate in the modulation of cardiac growth. The cloning of the ACE gene has made it possible to identify a deletion (D)-insertion (I) polymorphism that appears to affect the level of serum ACE activity. ...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.2143/AC.60.2.2005025
更新日期:2005-04-01 00:00:00
abstract:OBJECTIVE:The objective of this study was to analyse age-related changes in human myocardial nerve plexuses and collagen networks of the auricle of the right atrium in subjects in whom no cardiac diseases or pathology had been diagnosed. METHODS AND RESULTS:Morphometric analysis of acetylcholinesterase (AChE)-stained ...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.2143/AC.61.5.2017765
更新日期:2006-10-01 00:00:00
abstract:UNLABELLED:In order to detect myocardial viability in coronary artery disease patients (CAD) with a previous myocardial infarction and dysfunction of the left ventricle (LV), the reliability of the left atrioventricular plane displacement (LAVPD) during low dose dobutamine stress echocardiography (DSE), was validated. ...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:
更新日期:1995-01-01 00:00:00
abstract::Experimental demonstration that the external phonocardiogram is similar to the third derivative (rate of acceleration) of LV pressure, and that catecholamines cause a similar increase of the early systolic wave of the first derivative of LV pressure and of S1 prompted a study of the first sound during stress testing. ...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:
更新日期:1986-01-01 00:00:00
abstract::A follow-up study was carried out in 98 patients with congestive cardiomyopathy using clinical data and M-mode echocardiography. 59 patients survived (mean follow-up period 18 months), 39 patients died (mean survival period 12.6 months). Median survival time was 3 years. Prognosis was unfavorably affected by ECG signs...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:
更新日期:1981-01-01 00:00:00
abstract::Left ventricular-right atrial communication is a relatively rare surgically corrigible congenital heart defect. We report a case with review of the literature. ...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:
更新日期:1987-01-01 00:00:00
abstract::This is a review of the effects of E on the symptoms of CHF which affect patients' (pts) quality of life and the signs associated with pts' prognosis. The review is based on clinical studies which were included in the New Drug Application for Vasotec (enalapril maleate, MSD) in the United States. There were 3 open-lab...
journal_title:Acta cardiologica
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1991-01-01 00:00:00
abstract::We report the case of a 73-year-old man admitted to our hospital for acute hepatic failure. Antemortem diagnosis of systemic AA amyloidosis was made because of typical electrocardiographic and echocardiographic findings, in the absence of the classic clinical picture of kidney involvement. ...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.2143/AC.65.4.2053906
更新日期:2010-08-01 00:00:00