Production of monoclonal antibodies anti-Taenia crassiceps cysticerci with cross-reactivity with Taenia solium antigens.

Abstract:

:We describe the production of the potential monoclonal antibodies (MoAbs) using BALB/c mice immunized with vesicular fluid (VF)-Tcra (T. crassiceps) antigen. Immune sera presented anti-VF-Tcra (<20kD) IgG and IgM antibodies with cross-reactivity with T. solium (Tso) antigen (8-12, 14, and 18 kD). After cell fusion, we selected 33 anti-Tcra and anti-Tso reactive IgM-clones and 53 anti-Tcra specific IgG-clones, 5 of them also recognizing Tso antigens. Two clones identified the 8-14 and 18kD peptides of VF-Tcra.

authors

Espíndola NM,De Gaspari EN,Nakamura PM,Vaz AJ

doi

10.1590/s0036-46652000000300013

subject

Has Abstract

pub_date

2000-05-01 00:00:00

pages

175-7

issue

3

eissn

0036-4665

issn

1678-9946

pii

S0036-46652000000300013

journal_volume

42

pub_type

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