Treatment of acute hyponatremia: ensuring the excretion of a predictable amount of electrolyte-free water.

abstract：OBJECTIVES:To define a curriculum that outlines the core knowledge residents should possess upon completion of graduate training in order to be able to formulate and initiate a treatment plan for the critically ill patient. DATA SOURCES:Requirements for training program certification as outlined by the Accreditation C...

journal_title：Critical care medicine

authors：

更新日期：1995-11-01 00:00:00

abstract：OBJECTIVE:To cost adult intensive care by determining inputs to production, resource consumption per patient, and total cost per intensive care unit (ICU) stay. DESIGN:Prospective cost-accounting analysis of each patient stay in the ICU, over a 1-yr period. SETTING:An 11-bed, medical/surgical adult ICU, in a 932-bad ...

journal_title：Critical care medicine

authors： Noseworthy TW,Konopad E,Shustack A,Johnston R,Grace M

更新日期：1996-07-01 00:00:00

abstract：OBJECTIVE:Mitochondrial damage and dysfunction are thought to play an important role in the pathogenesis of sepsis-induced organ failures. Unfortunately, specific markers of mitochondrial damage in vital organs do not currently exist. Recently, carbomyl phosphate synthase (CPS)-1, a protein primarily localized to liver...

journal_title：Critical care medicine

authors： Crouser ED,Julian MW,Huff JE,Struck J,Cook CH

更新日期：2006-09-01 00:00:00

abstract：OBJECTIVE:This report will describe the preparations for and the provision of care of two patients with Ebola virus disease in the biocontainment unit at the University of Nebraska Medical Center. DATA SOURCES:Patient medical records. STUDY SELECTION:Not applicable. DATA EXTRACTION:Not applicable. DATA SYNTHESIS:No...

journal_title：Critical care medicine

authors： Johnson DW,Sullivan JN,Piquette CA,Hewlett AL,Bailey KL,Smith PW,Kalil AC,Lisco SJ

更新日期：2015-06-01 00:00:00

abstract：:We studied prospectively 40 critically ill neurosurgical patients who required prolonged mechanical ventilation to determine the current incidence of stress-related gastroduodenal erosions and ulcers, and to assess endoscopically the efficacy of acid-reducing prophylactic treatment. Nineteen patients were randomized t...

journal_title：Critical care medicine

authors： Reusser P,Gyr K,Scheidegger D,Buchmann B,Buser M,Zimmerli W

更新日期：1990-03-01 00:00:00

abstract：:Position of the CVP port on a flow-directed balloon-tip pulmonary arterial catheter affects the accuracy of both thermodilution cardiac output determinations and CVP measurements. Systemic allometry (the study of the growth of a part in relation to the total organism) has been used to determine an easily measured inde...

journal_title：Critical care medicine

authors： Borland LM

更新日期：1986-11-01 00:00:00

abstract：OBJECTIVES:To define the features of human amniotic mesenchymal stromal cell secretome and its protective properties in experimental models of acute brain injury. DESIGN:Prospective experimental study. SETTING:Laboratory research. SUBJECTS:C57Bl/6 mice. INTERVENTIONS:Mice subjected to sham or traumatic brain injury...

journal_title：Critical care medicine

authors： Pischiutta F,Brunelli L,Romele P,Silini A,Sammali E,Paracchini L,Marchini S,Talamini L,Bigini P,Boncoraglio GB,Pastorelli R,De Simoni MG,Parolini O,Zanier ER

更新日期：2016-11-01 00:00:00

abstract：OBJECTIVES:To investigate the effects of recombinant human erythropoietin on brain oxygenation in a model of diffuse traumatic brain injury. DESIGN:Adult male Wistar rats. SETTING:Neurosciences and physiology laboratories. INTERVENTIONS:Thirty minutes after diffuse traumatic brain injury (impact-acceleration model),...

journal_title：Critical care medicine

authors： Bouzat P,Millet A,Boue Y,Pernet-Gallay K,Trouve-Buisson T,Gaide-Chevronnay L,Barbier EL,Payen JF

更新日期：2013-05-01 00:00:00

abstract：OBJECTIVE:To evaluate the efficacy and tolerability of intravenous empiric treatment with meropenem compared with ceftazidime-tobramycin in patients with hospital-acquired lower respiratory tract infections. DESIGN:Prospective, nonblind, randomized trial. SETTING:Multicenter trial conducted at 22 centers. PATIENTS:T...

journal_title：Critical care medicine

authors： Sieger B,Berman SJ,Geckler RW,Farkas SA

更新日期：1997-10-01 00:00:00

abstract：:Recent advances in prenatal and neonatal care have increased the number of live births and extended the life expectancy of critically ill premature infants. These infants represent a formidable therapeutic challenge in that multisystem involvement and previously uncommon conditions, such as intravascular coagulation, ...

journal_title：Critical care medicine

authors： Aschinberh LC,Zeis PM,Hageman JR,Vidyasagar D

更新日期：1977-01-01 00:00:00

abstract：OBJECTIVE:To review recent advances in the use of transforming growth factor (TGF)-beta in acute lung injury and to apply this knowledge to understanding the pathophysiology of this syndrome. DATA SOURCES AND STUDY SELECTION:Published research and review articles in the English language related to the role of TGF-beta...

journal_title：Critical care medicine

authors： Dhainaut JF,Charpentier J,Chiche JD

更新日期：2003-04-01 00:00:00

abstract：OBJECTIVE:Preoperative intra-aortic balloon pumping (IABP) improves the results of complex coronary surgery. However, its insertion may be harmful or contraindicated in cases of severe and diffuse atherosclerosis of the descending aorta and peripheral arteries. We sought to evaluate the efficacy and safety of transbrac...

journal_title：Critical care medicine

authors： Onorati F,Bilotta M,Pezzo F,Impiombato B,Caroleo S,Santangelo E,Renzulli A

更新日期：2006-08-01 00:00:00

abstract：OBJECTIVES:The aim of this study was to analyze the effect of the International Nosocomial Infection Control Consortium's multidimensional approach on the reduction of ventilator-associated pneumonia in patients hospitalized in intensive care units. DESIGN:A prospective active surveillance before-after study. The stud...

journal_title：Critical care medicine

authors： Rosenthal VD,Rodrigues C,Álvarez-Moreno C,Madani N,Mitrev Z,Ye G,Salomao R,Ulger F,Guanche-Garcell H,Kanj SS,Cuéllar LE,Higuera F,Mapp T,Fernández-Hidalgo R,INICC members.

更新日期：2012-12-01 00:00:00

abstract：OBJECTIVE:Heatstroke is characterized by hyperthermia, vasoplegic shock, and cerebral ischemia and hypoxia. Hyperbaric oxygen (HBO) has been shown to reduce brain ischemia and behavioral dysfunction during cerebral artery occlusion. The efficacy of HBO therapy for resuscitation from heatstroke remains to be determined ...

journal_title：Critical care medicine

authors： Tsai HM,Gao CJ,Li WX,Lin MT,Niu KC

更新日期：2005-04-01 00:00:00

abstract：OBJECTIVE:To appraise the literature on the effect of initial renal replacement therapy (RRT) modality on clinical outcomes. DESIGN:Systematic review and meta-analysis. SETTING:Academic medical center. PATIENTS AND PARTICIPANTS:Adult critically ill patients with acute kidney injury. INTERVENTIONS:Continuous vs. int...

journal_title：Critical care medicine

authors： Bagshaw SM,Berthiaume LR,Delaney A,Bellomo R

更新日期：2008-02-01 00:00:00

abstract：BACKGROUND AND METHODS:In the present study, we evaluated the effect of N-acetylcysteine treatment in a nonseptic shock model induced by zymosan in the rat. Animals were randomly divided into eight groups (ten animals in each group). The first group was treated with ip administration of saline solution (0.90% NaCl) and...

journal_title：Critical care medicine

authors： Cuzzocrea S,Costantino G,Mazzon E,Caputi AP

更新日期：1999-08-01 00:00:00

abstract：OBJECTIVE:To develop definitions of infection that can be used in clinical trials in patients with sepsis. CONTEXT:Infection is a key component of the definition of sepsis, yet there is currently no agreement on the definitions that should be used to identify specific infections in patients with sepsis. Agreeing on a ...

journal_title：Critical care medicine

authors： Calandra T,Cohen J,International Sepsis Forum Definition of Infection in the ICU Consensus Conference.

更新日期：2005-07-01 00:00:00

abstract：:Cardiogenic shock is the most common cause of death in patients hospitalized with acute myocardial infarction and is associated with a poor prognosis. More than 75% of cases are due to extensive left ventricular infarction and ventricular failure. Other causes include right ventricular infarction and papillary muscle ...

journal_title：Critical care medicine

authors： Topalian S,Ginsberg F,Parrillo JE

更新日期：2008-01-01 00:00:00

abstract：OBJECTIVES:Extracorporeal cardiopulmonary resuscitation has shown survival benefit in select patients with refractory cardiac arrest but there is insufficient data on the frequency of different types of brain injury. We aimed to systematically review the prevalence, predictors of and survival from neurologic complicati...

journal_title：Critical care medicine

authors： Migdady I,Rice C,Deshpande A,Hernandez AV,Price C,Whitman GJ,Geocadin RG,Cho SM

更新日期：2020-07-01 00:00:00

abstract：:A new quantitative method for measuring the prognosis and severity of illness in terms of probability of survival was developed from 224 studies in an index population of 220 critically ill surgical patients. Patients were selected preoperatively to eliminate pre-existing cardiac disease, cirrhosis, nutritional debili...

journal_title：Critical care medicine

authors： Bland RD,Shoemaker WC

更新日期：1985-02-01 00:00:00

abstract：OBJECTIVES:To evaluate the association between length of ICU stay and 1-year mortality for elderly patients who survived to hospital discharge in the United States. DESIGN:Retrospective cohort study of a random sample of Medicare beneficiaries who survived to hospital discharge, with 1- and 3-year follow-up, stratifie...

journal_title：Critical care medicine

authors： Moitra VK,Guerra C,Linde-Zwirble WT,Wunsch H

更新日期：2016-04-01 00:00:00

abstract：OBJECTIVE:Adrenal failure is common in critically ill patients, particularly those with sepsis. As liver failure and sepsis are both associated with increased circulating levels of endotoxin and proinflammatory mediators and reduced levels of apoprotein-1/high-density lipoprotein, we postulated that adrenal failure may...

journal_title：Critical care medicine

authors： Marik PE,Gayowski T,Starzl TE,Hepatic Cortisol Research and Adrenal Pathophysiology Study Group.

更新日期：2005-06-01 00:00:00

abstract：BACKGROUND:Endotoxin (lipopolysaccharide [LPS]) has been associated with sepsis and the high mortality rate seen in septic shock. The administration of a small amount of LPS to healthy subjects produces a mild syndrome qualitatively similar to that seen in clinical sepsis. We used this model to test the efficacy of an ...

journal_title：Critical care medicine

authors： Bunnell E,Lynn M,Habet K,Neumann A,Perdomo CA,Friedhoff LT,Rogers SL,Parrillo JE

更新日期：2000-08-01 00:00:00

abstract：:In a prospective randomized study to determine whether prevention of colonization of Gram-negative bacteria results in prevention of Gram-negative bacterial infections, 96 intensive care patients were randomly allocated into a control group and a study group. The study group received oral nonabsorbable antimicrobial a...

journal_title：Critical care medicine

authors： Kerver AJ,Rommes JH,Mevissen-Verhage EA,Hulstaert PF,Vos A,Verhoef J,Wittebol P

更新日期：1988-11-01 00:00:00

abstract：OBJECTIVE:The successful management of an influenza pandemic will be reliant on the expertise of healthcare workers at high risk for occupationally acquired influenza. Recommended infection control measures for healthcare workers include surgical masks to protect against droplet-spread respiratory transmissible infecti...

journal_title：Critical care medicine

authors： Gralton J,McLaws ML

更新日期：2010-02-01 00:00:00

abstract：:We evaluated 95 extubated neonates to determine if certain risk factors could predict the development of laryngeal injury. Risk factors were recorded prospectively during the intubation period and correlated with laryngeal injury determined by laryngoscopy after extubation. Duration of intubation greater than or equal...

journal_title：Critical care medicine

authors： Fan LL,Flynn JW,Pathak DR

更新日期：1983-06-01 00:00:00

abstract：OBJECTIVE:Isoflurane, a volatile anesthetic agent, has been recognized for its potential neuroprotective properties and has antiapoptotic effects. We examined whether isoflurane posttreatment is protective against early brain injury after subarachnoid hemorrhage and determined whether this effect needs sphingosine-rela...

journal_title：Critical care medicine

authors： Altay O,Hasegawa Y,Sherchan P,Suzuki H,Khatibi NH,Tang J,Zhang JH

更新日期：2012-06-01 00:00:00

abstract：OBJECTIVE:To describe mechanical ventilation settings in adult patients treated for an acute respiratory distress syndrome with extracorporeal membrane oxygenation and assess the potential impact of mechanical ventilation settings on ICU mortality. DESIGN:Retrospective observational study. SETTING:Three international...

journal_title：Critical care medicine

authors： Schmidt M,Stewart C,Bailey M,Nieszkowska A,Kelly J,Murphy L,Pilcher D,Cooper DJ,Scheinkestel C,Pellegrino V,Forrest P,Combes A,Hodgson C

更新日期：2015-03-01 00:00:00

abstract：:The current investigation describes the morphological and pathophysiological effects of stroma-free hemoglobin solution (SFH) on the liver and kidney. One h after a 75% blood volume exchange in animals receiving 7% SFH, hepatic morphology was normal. Animals whose blood was similarly exchanged with 7% albumin demonstr...

journal_title：Critical care medicine

authors： Friedman HI,DeVenuto F

更新日期：1982-04-01 00:00:00

abstract：OBJECTIVE:Sepsis is a frequent cause of admission, but incidence rates based on administrative data have previously produced large differences in estimates. The aim of the study was to estimate the incidence of community-acquired sepsis based on patients' symptoms and clinical findings at arrival to the hospital. DESI...

journal_title：Critical care medicine

authors： Henriksen DP,Laursen CB,Jensen TG,Hallas J,Pedersen C,Lassen AT

更新日期：2015-01-01 00:00:00