Prevention of colonization and infection in critically ill patients: a prospective randomized study.

abstract：OBJECTIVES:To determine the accuracy of intramucosal pH (pHi) calculated using arterial bicarbonate instead of mucosal capillary bicarbonate in the Henderson-Hasselbalch equation. DESIGN:Simulation of progressive ischemia in mucosal capillary blood. SETTING:University research laboratory. SUBJECTS:Normal human blood...

journal_title：Critical care medicine

authors： Morgan TJ,Venkatesh B,Endre ZH

更新日期：1999-11-01 00:00:00

abstract：OBJECTIVES:To investigate the effects of recombinant human erythropoietin on brain oxygenation in a model of diffuse traumatic brain injury. DESIGN:Adult male Wistar rats. SETTING:Neurosciences and physiology laboratories. INTERVENTIONS:Thirty minutes after diffuse traumatic brain injury (impact-acceleration model),...

journal_title：Critical care medicine

authors： Bouzat P,Millet A,Boue Y,Pernet-Gallay K,Trouve-Buisson T,Gaide-Chevronnay L,Barbier EL,Payen JF

更新日期：2013-05-01 00:00:00

abstract：OBJECTIVE:Mannitol is widely used in hospitals worldwide to treat patients with high intracranial pressure and/or cerebral edema. One of the mechanisms by which mannitol is thought to affect intracranial pressure is by increasing the patient's serum osmolarity, but not the osmolarity in the brain or cerebrospinal fluid...

journal_title：Critical care medicine

authors： Polderman KH,van de Kraats G,Dixon JM,Vandertop WP,Girbes AR

更新日期：2003-02-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to quantify the effect of hypertonic saline solution on contused and noncontused brain tissue in patients with traumatic brain injury. We hypothesize that hypertonic saline would increase the volume of brain contusion while decreasing the volume of noncontused hemispheric areas. DES...

journal_title：Critical care medicine

authors： Lescot T,Degos V,Zouaoui A,Préteux F,Coriat P,Puybasset L

更新日期：2006-12-01 00:00:00

abstract：:Significant resistance was encountered when an attempt was made to withdraw a persistently wedged pulmonary artery catheter. A small amount of air was injected into the balloon lumen with great difficulty. This injection freed the catheter which was removed, but produced significant sudden hemoptysis and a pneumothora...

journal_title：Critical care medicine

authors： Farber DL,Rose DM,Bassell GM,Eugene J

更新日期：1981-06-01 00:00:00

abstract：OBJECTIVE:To evaluate the role of continuous lateral rotational therapy on the development of ventilator-associated pneumonia in patients requiring long-term mechanical ventilation. DESIGN:Prospective control study. SETTING:Chronic ventilator unit in tertiary care hospital. METHODS:Thirty-seven patients requiring lo...

journal_title：Critical care medicine

authors： Kirschenbaum L,Azzi E,Sfeir T,Tietjen P,Astiz M

更新日期：2002-09-01 00:00:00

abstract：OBJECTIVES:Severe coronavirus disease 2019 is associated with an extensive pneumonitis and frequent coagulopathy. We sought the true prevalence of thrombotic complications in critically ill patients with severe coronavirus disease 2019 on the ICU, with or without extracorporeal membrane oxygenation. DESIGN:We undertoo...

journal_title：Critical care medicine

authors： Mirsadraee S,Gorog DA,Mahon CF,Rawal B,Semple TR,Nicol ED,Arachchillage DRJ,Devaraj A,Price S,Desai SR,Ridge CA,Singh S,Padley SPG

更新日期：2021-01-06 00:00:00

abstract：OBJECTIVE:One in five Americans dies following treatment in an intensive care unit (ICU), and evidence indicates the need to improve end-of-life care for ICU patients. We conducted this study to elicit the views and experiences of ICU directors regarding barriers to optimal end-of-life care and to identify the type, av...

journal_title：Critical care medicine

authors： Nelson JE,Angus DC,Weissfeld LA,Puntillo KA,Danis M,Deal D,Levy MM,Cook DJ,Critical Care Peer Workgroup of the Promoting Excellence in End-of-Life Care Project.

更新日期：2006-10-01 00:00:00

abstract：:As of October 1985, 37 candidates have passed the final examination in intensive care for the Diploma of Fellow of the Faculty of Anaesthetists, Royal Australasian College of Surgeons (FFARACS). In September 1984, 23 of these successful candidates responded to a questionnaire seeking information on their educational e...

journal_title：Critical care medicine

authors： Byth PL,Harrison GA

更新日期：1986-06-01 00:00:00

abstract：OBJECTIVES:To assess whether sepsis-associated coagulopathy predicts hospital mortality. DESIGN:Retrospective cohort study. SETTING:One-thousand three-hundred beds urban academic medical center. PATIENTS:Six-thousand one-hundred forty-eight consecutive patients hospitalized between January 1, 2010, and December 31, ...

journal_title：Critical care medicine

authors： Lyons PG,Micek ST,Hampton N,Kollef MH

更新日期：2018-05-01 00:00:00

abstract：:Disseminated intravascular coagulation (DIC) is an acquired syndrome characterized by intravascular fibrin formation occurring in the course of a variety of severe diseases. In gram-negative sepsis, endotoxin is the bacterial component eliciting a cascade of tissue factor dependent hypercoagulable reactions mediated b...

journal_title：Critical care medicine

authors： ten Cate H

更新日期：2000-09-01 00:00:00

abstract：OBJECTIVES:Preclinical studies reveal the neuroprotective properties of xenon, especially when combined with hypothermia. The purpose of this study was to investigate the feasibility and cardiac safety of inhaled xenon treatment combined with therapeutic hypothermia in out-of-hospital cardiac arrest patients. DESIGN:A...

journal_title：Critical care medicine

authors： Arola OJ,Laitio RM,Roine RO,Grönlund J,Saraste A,Pietilä M,Airaksinen J,Perttilä J,Scheinin H,Olkkola KT,Maze M,Laitio TT

更新日期：2013-09-01 00:00:00

abstract：OBJECTIVE:To determine the association of pulmonary artery catheter (PAC) use with in-hospital mortality. DESIGN:Prospective, observational study. SETTING:The medical intensive care units (MICU) of two teaching hospitals. METHODS:The study included 751 adults who were admitted to the MICU, excluding those who stayed...

journal_title：Critical care medicine

authors： Afessa B,Spencer S,Khan W,LaGatta M,Bridges L,Freire AX

更新日期：2001-06-01 00:00:00

abstract：BACKGROUND:Prevalence and causes of sex-based differences in morbidity and mortality secondary to cardiovascular disease remain controversial. Cardiac troponin I (cTnI) is a sensitive and specific marker for myocardial injury. Serial cTnI measurements have been used to identify perioperative myocardial cell injury. OB...

journal_title：Critical care medicine

authors： Schwarzenberger JC,Sun LS,Pesce MA,Heyer EJ,Delphin E,Almeida GM,Wood M

更新日期：2003-03-01 00:00:00

abstract：OBJECTIVES:: To characterize the epidemiology and burden of early-onset, nonnosocomial candidemia. DESIGN:: Retrospective review of Cardinal Health Outcomes Research Database, which comprises all acute care admissions at participating hospitals. SETTING:: A total of 176 acute care hospitals. PATIENTS:: All patients ...

journal_title：Critical care medicine

authors： Shorr AF,Gupta V,Sun X,Johannes RS,Spalding J,Tabak YP

更新日期：2009-09-01 00:00:00

abstract：OBJECTIVE:To provide a comprehensive review of the issue related to the administration of sedative, analgesic, and neuromuscular blocking agents (NMBA) to patients who are receiving ventilatory support for acute respiratory distress syndrome (ARDS) with high-frequency oscillatory ventilation. RESULTS:Sedative, analges...

journal_title：Critical care medicine

authors： Sessler CN

更新日期：2005-03-01 00:00:00

abstract：OBJECTIVE:To determine the effectiveness of increasing the preoxygenation period with 100% oxygen in the critically ill patient from 4 to 8 mins in preparation for emergency tracheal intubation. DESIGN:Nonrandomized, controlled trial. SETTING:Large, level one trauma center, tertiary care intensive care unit. PATIENT...

journal_title：Critical care medicine

authors： Mort TC,Waberski BH,Clive J

更新日期：2009-01-01 00:00:00

abstract：OBJECTIVES:Sepsis results in organ dysfunction caused by a dysregulated host response, in part related to the immune response of a severe infection. Mesenchymal stromal cells are known to modulate the immune response, and expression of stromal cell-derived factor-1 regulates mobilization of neutrophils from the bone ma...

journal_title：Critical care medicine

authors： Kwon MY,Ghanta S,Ng J,Tsoyi K,Lederer JA,Bronson RT,El-Chemaly S,Chung SW,Liu X,Perrella MA

更新日期：2020-05-01 00:00:00

abstract：OBJECTIVE:To determine the effect that acute physiologic derangements have on outcome after subarachnoid hemorrhage (SAH) and to design a composite score summarizing these abnormalities. DESIGN:Prospective observational study. SETTING:Neuroscience intensive care unit in a tertiary care academic center. PATIENTS:Cons...

journal_title：Critical care medicine

authors： Claassen J,Vu A,Kreiter KT,Kowalski RG,Du EY,Ostapkovich N,Fitzsimmons BF,Connolly ES,Mayer SA

更新日期：2004-03-01 00:00:00

abstract：OBJECTIVE:To describe critical illnesses that occur commonly in patients with human immunodeficiency virus (HIV) infection. METHODS:We reviewed and summarized the literature on critical illness in HIV infection using a computerized MEDLINE search. SUMMARY:In the last 10 yrs, our perception of HIV infection and acquir...

journal_title：Critical care medicine

authors： Rosen MJ,Narasimhan M

更新日期：2006-09-01 00:00:00

abstract：:Cardiogenic shock is the most common cause of death in patients hospitalized with acute myocardial infarction and is associated with a poor prognosis. More than 75% of cases are due to extensive left ventricular infarction and ventricular failure. Other causes include right ventricular infarction and papillary muscle ...

journal_title：Critical care medicine

authors： Topalian S,Ginsberg F,Parrillo JE

更新日期：2008-01-01 00:00:00

abstract：OBJECTIVE:In children, like in adults, tracheal intubation is a painful procedure that may induce hypertension, tachycardia, and other undesirable hemodynamic disorders. Although premature neonates are very sensitive to pain and vulnerable to its long-term effects, the need for sedation before tracheal intubation is st...

journal_title：Critical care medicine

authors： Simon L,Trifa M,Mokhtari M,Hamza J,Treluyer JM

更新日期：2004-02-01 00:00:00

abstract：BACKGROUND:Millions of patients are discharged from intensive care units annually. These intensive care survivors and their families frequently report a wide range of impairments in their health status which may last for months and years after hospital discharge. OBJECTIVES:To report on a 2-day Society of Critical Car...

journal_title：Critical care medicine

authors： Needham DM,Davidson J,Cohen H,Hopkins RO,Weinert C,Wunsch H,Zawistowski C,Bemis-Dougherty A,Berney SC,Bienvenu OJ,Brady SL,Brodsky MB,Denehy L,Elliott D,Flatley C,Harabin AL,Jones C,Louis D,Meltzer W,Muldoon SR,Pa

更新日期：2012-02-01 00:00:00

abstract：OBJECTIVE:Intravesical pressure measurement is considered to be the gold standard for the assessment of intra-abdominal pressure. However, this method is indirect and depends on a physiologic bladder function. We evaluated a modified piezoresistive technique and a water-capsule technique for direct and continuous intra...

journal_title：Critical care medicine

authors： Schachtrupp A,Henzler D,Orfao S,Schaefer W,Schwab R,Becker P,Schumpelick V

更新日期：2006-03-01 00:00:00

abstract：OBJECTIVE:Using a modification of the Bohr equation, single-breath carbon dioxide capnography is a noninvasive technology for calculating physiologic dead space (V(D)/V(T)). The objective of this study was to identify a minimal V(D)/V(T) value for predicting successful extubation from mechanical ventilation in pediatri...

journal_title：Critical care medicine

authors： Hubble CL,Gentile MA,Tripp DS,Craig DM,Meliones JN,Cheifetz IM

更新日期：2000-06-01 00:00:00

abstract：:High-risk patients who survived general (noncardiac) surgery were observed to have cardiac index (CI) values averaging 4.5 L/min.m2, oxygen delivery (DO2) greater than 600 ml/min.m2, and oxygen consumption (VO2) 170 ml/min.m2 during the first 2 or three days postoperatively. Patients who subsequently died maintained r...

journal_title：Critical care medicine

authors： Shoemaker WC,Kram HB,Appel PL

更新日期：1990-01-01 00:00:00

abstract：OBJECTIVE:To evaluate the effect of spontaneous gasping on cardiorespiratory functions and the ability to resuscitate during experimental cardiac arrest. DATA SOURCES:Studies in rat and pig models during cardiac arrest and cardiopulmonary resuscitation (CPR). STUDY SELECTION:We retrospectively examined the role of sp...

journal_title：Critical care medicine

authors： Yang L,Weil MH,Noc M,Tang W,Turner T,Gazmuri RJ

更新日期：1994-05-01 00:00:00

abstract：OBJECTIVE:The role of systemic corticosteroids in pathophysiology and treatment of acute respiratory distress syndrome is controversial. Use of prehospital systemic corticosteroid therapy may prevent the development of acute respiratory distress syndrome and improve hospital outcomes. DESIGN:This is a preplanned retro...

journal_title：Critical care medicine

authors： Karnatovskaia LV,Lee AS,Gajic O,Festic E,U.S. Critical Illness and Injury Trials Group: Lung Injury Prevention Study Investigators (USCIITG–LIPS).

更新日期：2013-07-01 00:00:00

abstract：OBJECTIVE:To discuss the potential therapeutic value of intraluminal oxygenation of the gut in critical illness. DATA SOURCES:Relevant articles published in the English language literature. STUDY SELECTION:No special study has been carried out for the present presentation. DATA EXTRACTION:Information from the litera...

journal_title：Critical care medicine

authors： Haglund U

更新日期：1993-02-01 00:00:00

abstract：OBJECTIVE:To evaluate the physiology and pharmacokinetics of a novel hemoglobin-based oxygen carrier of bovine origin. DESIGN:Randomized, single-blind, placebo-controlled, dose-escalation study. SETTING:The Upjohn Research Clinics (Kalamazoo, MI). SUBJECTS:Normal healthy adult men between the ages of 18 and 45 yrs. ...

journal_title：Critical care medicine

authors： Hughes GS Jr,Antal EJ,Locker PK,Francom SF,Adams WJ,Jacobs EE Jr

更新日期：1996-05-01 00:00:00