Sedation, analgesia, and neuromuscular blockade for high-frequency oscillatory ventilation.

abstract：:Instantaneous heart rate, indices of long-term and short-term heart-rate variability (HRV), and transcutaneous O2 (PtcO2) and CO2 (PtcCO2) tensions were recorded simultaneously on 164 occasions in 16 neonates. There was significant inverse correlation between PtcCO2 and both HRV indices, while no linear correlation wa...

journal_title：Critical care medicine

authors： Aärimaa T,Kero P,Välimäki I

更新日期：1985-01-01 00:00:00

abstract：OBJECTIVES:The epidemiology of chronic critical illness is not well known. We aimed to estimate the prevalence, mortality, and costs associated with chronic critical illness in Japan. DESIGN:A nationwide inpatient administrative database study in Japan from April 2011 to March 2018. SETTING:Six hundred seventy-nine a...

journal_title：Critical care medicine

authors： Ohbe H,Matsui H,Fushimi K,Yasunaga H

更新日期：2021-01-01 00:00:00

abstract：:A new iridium/iridium-oxide electrode heated to 42 degrees C was used to monitor transcutaneous carbon dioxide levels during surgery in 27 adult patients. The purpose of this study was to compare arterial and transcutaneous CO2 values. This metal electrode performed similarly to glass CO2 electrodes. In addition, its ...

journal_title：Critical care medicine

authors： Williams R,Riker R,Narkewicz M,Lucey JF

更新日期：1985-10-01 00:00:00

abstract：:To determine the influence of arachidonic acid metabolites on acute lung injury induced by glass bead embolism, two groups of animals were studied before and after the pulmonary artery pressure was doubled by glass bead embolism. One group represented an untreated time control (n = 6) while the second group (n = 6) wa...

journal_title：Critical care medicine

authors： Calvin JE,Dervin G

更新日期：1988-09-01 00:00:00

abstract：:We describe the use of continuous negative extrathoracic pressure to treat successfully the adult respiratory distress syndrome in a 19-yr-old woman who resisted the application of positive airway pressure. Arterial hypoxemia was reversed with -26 cm H2O of extrathoracic pressure, produced by a modified Emerson iron l...

journal_title：Critical care medicine

authors： Morris AH,Elliott CG

更新日期：1985-11-01 00:00:00

abstract：OBJECTIVE:To evaluate the effects of monoclonal antibody to tumor necrosis factor (TNF)-alpha on the hemodynamic alterations and survival rate in rats subjected to intestinal ischemia/reperfusion. DESIGN:Prospective, randomized study. SETTING:Animal laboratory of an institute for research in traumatology. SUBJECTS:M...

journal_title：Critical care medicine

authors： Yao YM,Bahrami S,Redl H,Schlag G

更新日期：1996-09-01 00:00:00

abstract：OBJECTIVE:To compare the effects of continuous negative extrathoracic pressure (CNEP) and positive end-expiratory pressure (PEEP) at the same level of transpulmonary pressure. DESIGN:Prospective analysis. SETTING:Medical intensive care unit of a university hospital. PATIENTS:Nine consecutive acute lung injury patien...

journal_title：Critical care medicine

authors： Borelli M,Benini A,Denkewitz T,Acciaro C,Foti G,Pesenti A

更新日期：1998-06-01 00:00:00

abstract：:The ability of ACTH-(1-24) to prolong survival and to extend the deadline for effective blood reinfusion has been studied in a model of lethal hypovolemic shock in the rat. Anesthetized rats were bled to a mean arterial pressure of 18 to 25 mm Hg and then subjected to one of the following iv treatments: a) saline; b) ...

journal_title：Critical care medicine

authors： Guarini S,Tagliavini S,Bazzani C,Ferrari W,Bertolini A

更新日期：1990-08-01 00:00:00

abstract：OBJECTIVE:To determine alterations in intestinal epithelial permeability to solutes in burn injured rats with and without Enterococcus faecalis infection and the role of neutrophils in the intestinal permeability changes. DESIGN:Prospective sham-controlled animal study. SETTING:University research laboratory. SUBJEC...

journal_title：Critical care medicine

authors： Samonte VA,Goto M,Ravindranath TM,Fazal N,Holloway VM,Goyal A,Gamelli RL,Sayeed MM

更新日期：2004-11-01 00:00:00

abstract：OBJECTIVE:Initial success with chimeric antigen receptor-modified T cell therapy for relapsed/refractory acute lymphoblastic leukemia is leading to expanded use through multicenter trials. Cytokine release syndrome, the most severe toxicity, presents a novel critical illness syndrome with limited data regarding diagnos...

journal_title：Critical care medicine

authors： Fitzgerald JC,Weiss SL,Maude SL,Barrett DM,Lacey SF,Melenhorst JJ,Shaw P,Berg RA,June CH,Porter DL,Frey NV,Grupp SA,Teachey DT

更新日期：2017-02-01 00:00:00

abstract：:The hemodynamic effects of digitalis were examined in ten patients with acute cardiac failure. Administration of 10 micrograms/kg of digoxin iv resulted in significant increases in cardiac index, stroke volume index, and left ventricular stroke work index within one hour in five patients with acute myocardial infarcti...

journal_title：Critical care medicine

authors： Rackow EC,Packman MI,Weil MH

更新日期：1987-11-01 00:00:00

abstract：OBJECTIVES:To determine if prior total body hyperthermia protected against subsequent acute ileitis induced by the cytotoxic lectin, ricin, in rats. The time course of heat shock mRNA and protein expression in the ileum was determined. The effects of heat stress on small intestinal mucosal integrity, arachidonic acid m...

journal_title：Critical care medicine

authors： Stojadinovic A,Kiang J,Goldhill J,Matin D,Smallridge R,Galloway R,Shea-Donohue T

更新日期：1997-02-01 00:00:00

abstract：BACKGROUND:Procalcitonin (PCT), a marker of bacterial sepsis, may also act as a mediator of the inflammatory response to infection, and thus influence outcome. OBJECTIVE:To investigate the relationship between PCT, interleukin (IL)-10, tumor necrosis factor (TNF), organ failure, and mortality in pediatric septic shock...

journal_title：Critical care medicine

authors： Hatherill M,Tibby SM,Turner C,Ratnavel N,Murdoch IA

更新日期：2000-07-01 00:00:00

abstract：:Arterial and transcutaneous O2 (PtcO2) and CO2 (PtcCO2) tensions, arterial O2 saturations (SaO2) and P50 values were measured in 47 patients before extubation. In order to unmask ventilation to perfusion (VA/Q) inequality, all variables were obtained without CPAP and with FIO2 of 0.40 as well as with CPAP of 5 cm H2O ...

journal_title：Critical care medicine

authors： Tahvanainen J,Nikki P

更新日期：1983-09-01 00:00:00

abstract：BACKGROUND:Hemoglobin (Hb) induces vasoconstriction by heme group binding nitric oxide in an irreversible fashion. Recent in vitro studies indicate that the thiol groups in Hb reversibly bind nitric oxide and participate in trans-nitrosylation reactions with other thiols. Sepsis is a pathophysiologic state characterize...

journal_title：Critical care medicine

authors： Tejedor C,Lorente JA,Delgado MA,Fernández-Segoviano P,De Paula M,Tobalina R,Alonso M,Moscoso A,Soto F,Blázquez J,Esteban A

更新日期：2002-11-01 00:00:00

abstract：:Sepsis and resulting multiple system organ failure are the leading causes of mortality in intensive care units. Although it is generally appreciated that rampant, deregulated inflammatory pathways play a major role in sepsis, a comprehensive understanding based on the integrated response of multiple signal transductio...

journal_title：Critical care medicine

authors： Nguyen A,Yaffe MB

更新日期：2003-01-01 00:00:00

abstract：OBJECTIVES:To determine whether glucose utilization and metabolic substrate (glucose and fat) oxidation could be manipulated in patients with secondary multiple organ dysfunction syndrome. DESIGN:Prospective study. SETTING:Intensive care units (ICU) of two university hospitals. PATIENTS:Eight adults free of hepatic ...

journal_title：Critical care medicine

authors： Arnold J,Campbell IT,Hipkin LJ,Keegan M,Jenkins S,O'Sullivan E,Chadwick S

更新日期：1995-01-01 00:00:00

abstract：BACKGROUND:Early excision with autograft-allograft closure is standard in severe burn management. Cadaver skin is associated with risks such as antigenicity, infection, and limited availability and shelf life. Previous studies have shown that Integra is safe to use in burns of <20% total body surface area. However, the...

journal_title：Critical care medicine

authors： Branski LK,Herndon DN,Pereira C,Mlcak RP,Celis MM,Lee JO,Sanford AP,Norbury WB,Zhang XJ,Jeschke MG

更新日期：2007-11-01 00:00:00

abstract：:To achieve normocarbia during conventional mechanical ventilation, ventilator settings are determined initially on the basis of body weight. The best ventilator settings for CO2 elimination during high-frequency jet ventilation (HFJV) have not been so clearly defined. A recent study has suggested that eucarbia will be...

journal_title：Critical care medicine

authors： Bayly R,Sladen A,Tyler IL,Echegaray RF,Klain M,Guntupalli K

更新日期：1988-01-01 00:00:00

abstract：OBJECTIVES:Mild decrease in core temperature (therapeutic hypothermia) provides lasting neuroprotection following cardiac arrest or cerebral ischemia. However, current methods for producing therapeutic hypothermia trigger a cold-defense response that must be countered by sedatives, muscle paralytics, and mechanical ven...

journal_title：Critical care medicine

authors： Feketa VV,Zhang Y,Cao Z,Balasubramanian A,Flores CM,Player MR,Marrelli SP

更新日期：2014-05-01 00:00:00

abstract：:Ischemia of the intestines damages the permeability of the intestinal wall, allowing lipopolysaccharide (LPS) (endotoxin) to leak from the gut lumen into the blood circulation, causing shock and death. We measured LPS levels associated with corticosteroid treatment vs. no treatment in cats whose superior mesenteric ar...

journal_title：Critical care medicine

authors： Gaffin SL,Gathiram P,Wells MT,Brock-Utne JG

更新日期：1986-10-01 00:00:00

abstract：OBJECTIVE:To determine the limits of agreement between the cardiac output and volumetric data estimated by impedance cardiography with the cardiac output determined by thermodilution and the left ventricular ejection fraction and end-diastolic volume estimated from left ventriculography. DESIGN:A prospective study. S...

journal_title：Critical care medicine

authors： Marik PE,Pendelton JE,Smith R

更新日期：1997-09-01 00:00:00

abstract：:Estimations of blood glucose in the range 0-80 mg/dl were performed using the Chemstrip bG and StatTek Glucose Low Level test strips. Estimations of glucose levels closely approximated values obtained by a quantitative, enzymatic reference method; both appear to be excellent screening tests for hypoglycemia. There wer...

journal_title：Critical care medicine

authors： Maisels MJ,Lee CA

更新日期：1983-04-01 00:00:00

abstract：OBJECTIVE:Oxygenation measured 24 hours after acute respiratory distress syndrome onset more accurately stratifies risk, relative to oxygenation at onset, in both children and adults. However, waiting 24 hours is problematic, especially for interventions that are more efficacious early in the disease course. We aimed t...

journal_title：Critical care medicine

authors： Yehya N,Thomas NJ,Khemani RG

更新日期：2018-04-01 00:00:00

abstract：OBJECTIVE:To directly compare the cerebrovascular effects of norepinephrine and dopamine in patients with acute traumatic brain injury. DESIGN:Prospective randomized crossover trial. SETTING:Neurosciences critical care unit of a university hospital. PATIENTS:Ten acutely head-injured patients requiring vasoactive dru...

journal_title：Critical care medicine

authors： Steiner LA,Johnston AJ,Czosnyka M,Chatfield DA,Salvador R,Coles JP,Gupta AK,Pickard JD,Menon DK

更新日期：2004-04-01 00:00:00

abstract：OBJECTIVES:Anaphylactic shock is associated with severe hypotension. Potassium channel blockers, such as 4-aminopyridine, induce vasoconstriction. The objective of this study was to test the ability of 4-aminopyridine to restore blood pressure and increase survival in anaphylactic shock. DESIGN:Experimental study. SE...

journal_title：Critical care medicine

authors： Bellou A,Al-Hammadi S,Aburawi EH,Dhanasekaran S,Nemmar A,Oulhaj A,Shafiuallah M,Zerrouki M,Yasin J,Bellou L,Alper SL,Bellou S,Kazzam E

更新日期：2016-11-01 00:00:00

abstract：OBJECTIVE:To investigate the interaction and involvement of hydrogen sulfide and transient receptor potential vanilloid type 1 in the pathogenesis of sepsis. Hydrogen sulfide has been demonstrated to be involved in many inflammatory states including sepsis. Its contribution in neurogenic inflammation has been suggested...

journal_title：Critical care medicine

authors： Ang SF,Moochhala SM,Bhatia M

更新日期：2010-02-01 00:00:00

abstract：OBJECTIVE:To determine the role of toll-like receptor 2 in cardiac dysfunction during polymicrobial sepsis. DESIGN:Controlled animal study. SETTING:University hospital research laboratory. SUBJECTS:Male C57BL/6, wild-type, toll-like receptor 2-/-. INTERVENTION:Polymicrobial peritonitis, a clinically relevant model ...

journal_title：Critical care medicine

authors： Zou L,Feng Y,Chen YJ,Si R,Shen S,Zhou Q,Ichinose F,Scherrer-Crosbie M,Chao W

更新日期：2010-05-01 00:00:00

abstract：OBJECTIVE:In 2003, critical care and infectious disease experts representing 11 international organizations developed management guidelines for the use of corticosteroid therapy in patients with sepsis and septic shock that would be of practical use for the bedside clinician, under the auspices of the Surviving Sepsis ...

journal_title：Critical care medicine

authors： Keh D,Sprung CL

更新日期：2004-11-01 00:00:00

abstract：OBJECTIVE:The objectives of this study were to evaluate safety (primary) and clinical efficacy (secondary) of the humanized monoclonal anti-L-selectin antibody aselizumab in severely injured patients. DESIGN:Prospective phase II, parallel group, double-blind, randomized, placebo-controlled clinical trial. SETTING:Fou...

journal_title：Critical care medicine

authors： Seekamp A,van Griensven M,Dhondt E,Diefenbeck M,Demeyer I,Vundelinckx G,Haas N,Schaechinger U,Wolowicka L,Rammelt S,Stroobants J,Marzi I,Brambrink AM,Dziurdzik P,Gasiorowski J,Redl H,Beckert M,Khan-Boluki J

更新日期：2004-10-01 00:00:00