Improving long-term outcomes after discharge from intensive care unit: report from a stakeholders' conference.

abstract：OBJECTIVES:To determine whether pulse oximetry is accurate and if it correlates with arterial blood gas saturation in pediatric patients with sickle cell anemia. DESIGN:Prospective, comparative study using a convenience sample of patients with sickle cell anemia who had simultaneous arterial blood gas sampling and pul...

journal_title：Critical care medicine

authors： Fitzgerald RK,Johnson A

更新日期：2001-09-01 00:00:00

abstract：OBJECTIVE:A hallmark of amniotic fluid embolism is the induction of coagulation defects. Little is known about the nature of these defects or the causative agent or agents. The purpose of this study was to assess the effects of meconium containing (native) meconium-amniotic-fluid infusion (MAFI) and meconium-free (cent...

journal_title：Critical care medicine

authors： Petroianu GA,Altmannsberger SH,Maleck WH,Assmus HP,Friedberg C,Bergler WF,Rüfer R

更新日期：1999-02-01 00:00:00

abstract：OBJECTIVE:Adrenal failure is common in critically ill patients, particularly those with sepsis. As liver failure and sepsis are both associated with increased circulating levels of endotoxin and proinflammatory mediators and reduced levels of apoprotein-1/high-density lipoprotein, we postulated that adrenal failure may...

journal_title：Critical care medicine

authors： Marik PE,Gayowski T,Starzl TE,Hepatic Cortisol Research and Adrenal Pathophysiology Study Group.

更新日期：2005-06-01 00:00:00

abstract：OBJECTIVE:In critically ill patients, hepatic dysfunction is regarded as a late organ failure associated with poor prognosis. We investigated the incidence and prognostic implications of early hepatic dysfunction (serum bilirubin >2 mg/dL within 48 hrs of admission). DESIGN:Prospective, multicenter cohort study. SETT...

journal_title：Critical care medicine

authors： Kramer L,Jordan B,Druml W,Bauer P,Metnitz PG,Austrian Epidemiologic Study on Intensive Care, ASDI Study Group.

更新日期：2007-04-01 00:00:00

abstract：OBJECTIVES:Studies have shown contradicting results on the association of nursing workload and mortality. Most of these studies expressed workload as patients per nurse ratios; however, this does not take into account that some patients require more nursing time than others. Nursing time can be quantified by tools like...

journal_title：Critical care medicine

authors： Margadant C,Wortel S,Hoogendoorn M,Bosman R,Spijkstra JJ,Brinkman S,de Keizer N

更新日期：2020-01-01 00:00:00

abstract：OBJECTIVES:Fever is common and associated with increased mortality among patients admitted to adult ICUs, yet recent literature suggests that the incidence of fever may be decreasing. The objective of this study was to determine whether the incidence of fever in adult ICUs changed over time and the factors responsible ...

journal_title：Critical care medicine

authors： Niven DJ,Stelfox HT,Shahpori R,Laupland KB

更新日期：2013-08-01 00:00:00

abstract：OBJECTIVE:To analyze the effects of an extracorporeal bioartificial liver containing alginate bead-entrapped hepatocytes on pigs with ischemia-induced acute hepatic failure. DESIGN:Prospective animal study. SETTING:University and INSERM laboratory. SUBJECTS:Fifteen Large White/Pietrin female pigs weighing 20-30 kg. ...

journal_title：Critical care medicine

authors： Desille M,Mahler S,Seguin P,Mallédant Y,Frémond B,Sébille V,Bouix A,Desjardins JF,Joly A,Desbois J,Lebreton Y,Campion JP,Clément B

更新日期：2002-03-01 00:00:00

abstract：OBJECTIVES:To compare sleep, work hours, and behavioral alertness in faculty and fellows during a randomized trial of nighttime in-hospital intensivist staffing compared with a standard daytime intensivist model. DESIGN:Prospective observational study. SETTING:Medical ICU of a tertiary care academic medical center du...

journal_title：Critical care medicine

authors： Bakhru RN,Basner M,Kerlin MP,Halpern SD,Hansen-Flaschen J,Rosen IM,Dinges DF,Schweickert WD

更新日期：2019-07-01 00:00:00

abstract：OBJECTIVE:Sepsis and acute lung injury continue to be major causes of morbidity and mortality worldwide despite advances in our understanding of pathophysiology and the discovery of new management strategies. Recent investigations show that stem cells may be beneficial as prognostic biomarkers and novel therapeutic str...

journal_title：Critical care medicine

authors： Cribbs SK,Matthay MA,Martin GS

更新日期：2010-12-01 00:00:00

abstract：OBJECTIVE:To evaluate the frequency and clinical correlates of ultrafilterable hypomagnesemia in neonates admitted to the neonatal intensive care unit (ICU). DESIGN:Prospective, observational study. SETTING:Massachusetts General Hospital and Mount Auburn Hospital. PATIENTS:A total of 117 patients (84 neonatal ICU pa...

journal_title：Critical care medicine

authors： Munoz R,Khilnani P,Ziegler J,Salem M,Catlin EA,Nussbaum S,Todres ID,Chernow B

更新日期：1994-05-01 00:00:00

abstract：OBJECTIVES:Racial/ethnic differences in palliative care resource use after stroke have been recognized, but it is unclear whether patient or hospital characteristics drive this disparity. We sought to determine whether palliative care use after intracerebral hemorrhage and ischemic stroke differs between hospitals serv...

journal_title：Critical care medicine

authors： Faigle R,Ziai WC,Urrutia VC,Cooper LA,Gottesman RF

更新日期：2017-12-01 00:00:00

abstract：OBJECTIVE:The role of systemic corticosteroids in pathophysiology and treatment of acute respiratory distress syndrome is controversial. Use of prehospital systemic corticosteroid therapy may prevent the development of acute respiratory distress syndrome and improve hospital outcomes. DESIGN:This is a preplanned retro...

journal_title：Critical care medicine

authors： Karnatovskaia LV,Lee AS,Gajic O,Festic E,U.S. Critical Illness and Injury Trials Group: Lung Injury Prevention Study Investigators (USCIITG–LIPS).

更新日期：2013-07-01 00:00:00

abstract：OBJECTIVES:Mild decrease in core temperature (therapeutic hypothermia) provides lasting neuroprotection following cardiac arrest or cerebral ischemia. However, current methods for producing therapeutic hypothermia trigger a cold-defense response that must be countered by sedatives, muscle paralytics, and mechanical ven...

journal_title：Critical care medicine

authors： Feketa VV,Zhang Y,Cao Z,Balasubramanian A,Flores CM,Player MR,Marrelli SP

更新日期：2014-05-01 00:00:00

abstract：OBJECTIVE:To determine prevalence, risk factors, and outcome of thrombocytopenia in medical intensive care patients. DESIGN:Prospective observational study. SETTING:The 12-bed medical intensive care unit of a university hospital. PATIENTS:All consecutively admitted patients with normal platelet count at admission an...

journal_title：Critical care medicine

authors： Strauss R,Wehler M,Mehler K,Kreutzer D,Koebnick C,Hahn EG

更新日期：2002-08-01 00:00:00

abstract：OBJECTIVE:The neuroprotective effects of the noble gas xenon are well known. Argon, in contrast to xenon, is abundant, inexpensive, and therefore widely applicable. In this study, we analyzed the possible neuroprotective role of argon in an in vivo rat model of acute focal cerebral ischemia. DESIGN:Controlled laborato...

journal_title：Critical care medicine

authors： Ryang YM,Fahlenkamp AV,Rossaint R,Wesp D,Loetscher PD,Beyer C,Coburn M

更新日期：2011-06-01 00:00:00

abstract：OBJECTIVES:The purpose of this study was to determine the accuracy of clinical diagnoses compared to autopsy findings in critically ill patients in the current medical era. DESIGN:We conducted a retrospective, blinded review of matched medical records and postmortem findings in patients who died between June 2006 and ...

journal_title：Critical care medicine

authors： Fröhlich S,Ryan O,Murphy N,McCauley N,Crotty T,Ryan D

更新日期：2014-02-01 00:00:00

abstract：OBJECTIVES:The main objective of the study was to determine the prevalence of venous thromboembolism events in patients infected with severe acute respiratory syndrome coronavirus 2 requiring venovenous extracorporeal membrane oxygenation. The secondary objective was to compare venous thromboembolism events and coagula...

journal_title：Critical care medicine

authors： Parzy G,Daviet F,Puech B,Sylvestre A,Guervilly C,Porto A,Hraiech S,Chaumoitre K,Papazian L,Forel JM

更新日期：2020-10-01 00:00:00

abstract：OBJECTIVES:To evaluate the frequency of unsuspected posterior vessel wall penetration of the internal jugular vein during ultrasound-guided needle cannulation. DESIGN:Prospective, single-blinded observational study. SETTING:Urban level I emergency department with an annual census of 80,000. PATIENTS:Residents who ha...

journal_title：Critical care medicine

authors： Blaivas M,Adhikari S

更新日期：2009-08-01 00:00:00

abstract：OBJECTIVE:The objective of this study was to test the hypothesis that cocaine-induced cerebral vasodilation in newborn sheep is mediated via beta-adrenergic receptor activation. DESIGN:The cerebral effects of a single intravenous injection of cocaine (4 mg/kg) given 30 mins after pretreatment with propranolol (1 mg/kg...

journal_title：Critical care medicine

authors： O'Brien TP,Pane MA,Traystman RJ,Gleason CA

更新日期：1999-04-01 00:00:00

abstract：BACKGROUND:Glycemic control is increasingly being recognized as a priority in the treatment of critically ill patients. Titration and monitoring of insulin infusions involve frequent blood glucose measurement to achieve target glucose ranges and prevent adverse events related to hypoglycemia. Therefore, it is imperativ...

journal_title：Critical care medicine

authors： Kanji S,Buffie J,Hutton B,Bunting PS,Singh A,McDonald K,Fergusson D,McIntyre LA,Hebert PC

更新日期：2005-12-01 00:00:00

abstract：OBJECTIVES:Our primary goal was to evaluate the impact on in-hospital mortality rate of adequate empirical antibiotic therapy, after controlling for confounding variables, in a cohort of patients admitted to the intensive care unit (ICU) with sepsis. The impact of adequate empirical antibiotic therapy on early (<3 days...

journal_title：Critical care medicine

authors： Garnacho-Montero J,Garcia-Garmendia JL,Barrero-Almodovar A,Jimenez-Jimenez FJ,Perez-Paredes C,Ortiz-Leyba C

更新日期：2003-12-01 00:00:00

abstract：OBJECTIVE:To test the hypothesis that the lectin-like domain of tumor necrosis factor, mimicked by the TIP peptide, can improve lung function after unilateral orthotopic lung isotransplantation. Because of a lack of a specific treatment for ischemia reperfusion-mediated lung injury, accompanied by a disrupted barrier i...

journal_title：Critical care medicine

authors： Hamacher J,Stammberger U,Roux J,Kumar S,Yang G,Xiong C,Schmid RA,Fakin RM,Chakraborty T,Hossain HM,Pittet JF,Wendel A,Black SM,Lucas R

更新日期：2010-03-01 00:00:00

abstract：:Nine ventilator-dependent patients were successfully weaned from mechanical ventilatory support by high-frequency jet ventilation. All patients had been on ventilatory support for at least 2 wk, and had not responded to attempts at weaning by intermittent mandatory ventilation. ...

journal_title：Critical care medicine

authors： Klain M,Kalla R,Sladen A,Guntupalli K

更新日期：1984-09-01 00:00:00

abstract：OBJECTIVE:The mortality of critically ill patients associated with intestinal ischemia/reperfusion remains very high, which results from multiorgan dysfunction or failure due to intestinal injury induced by intestinal ischemia/reperfusion. This study was carried out to investigate whether intestinal ischemia/reperfusio...

journal_title：Critical care medicine

authors： Zhou J,Huang WQ,Li C,Wu GY,Li YS,Wen SH,Lei WL,Liu KX

更新日期：2012-08-01 00:00:00

abstract：:The intensive care unit (ICU) represents a hospital setting in which death and discussion about end-of-life care are common, yet these conversations are often difficult. Such difficulties arise, in part, because a family may be facing an unexpected poor prognosis associated with an acute illness or exacerbation and, i...

journal_title：Critical care medicine

authors： Curtis JR,Patrick DL,Shannon SE,Treece PD,Engelberg RA,Rubenfeld GD

更新日期：2001-02-01 00:00:00

abstract：OBJECTIVE:Exposure of neutrophils to low doses of bacterial lipopolysaccharides enhances their readiness to respond with inflammatory mediator generation including oxygen radical formation to a subsequently applied inflammatory stimulus ("priming"). In the present study, we investigated the role of lipid mediator synth...

journal_title：Critical care medicine

authors： Sibelius U,Hattar K,Hoffmann S,Mayer K,Grandel U,Schenkel A,Seeger W,Grimminger F

更新日期：2002-10-01 00:00:00

abstract：OBJECTIVES:We previously reported gene expression-based endotypes of pediatric septic shock, endotypes A and B, and that corticosteroid exposure was independently associated with increased mortality among pediatric endotype A patients. The Vasopressin vs Norepinephrine as Initial Therapy in Septic Shock trial tested th...

journal_title：Critical care medicine

authors： Wong HR,Hart KW,Lindsell CJ,Sweeney TE

更新日期：2021-01-01 00:00:00

abstract：:Data at ICU admission and after 24 h in the ICU were collected on 755 patients, to derive multiple logistic regression models for predicting hospital mortality. The derived models contained relatively few and easily obtained variables. The weight associated with each variable was determined objectively. There were sev...

journal_title：Critical care medicine

authors： Lemeshow S,Teres D,Pastides H,Avrunin JS,Steingrub JS

更新日期：1985-07-01 00:00:00

abstract：OBJECTIVES:To determine bronchoalveolar lavage (BAL) fluid concentrations of keratinocyte growth factor (KGF) and hepatocyte growth factor (HGF), two potent growth factors for alveolar type II epithelial cells, in patients with acute respiratory distress syndrome (ARDS). DESIGN:Prospective study. SETTING:An adult tra...

journal_title：Critical care medicine

authors： Stern JB,Fierobe L,Paugam C,Rolland C,Dehoux M,Petiet A,Dombret MC,Mantz J,Aubier M,Crestani B

更新日期：2000-07-01 00:00:00

abstract：OBJECTIVE:To compare urea nitrogen removal by continuous hemodiafiltration vs. functional native kidneys in critically ill, septic patients receiving > 2 g of amino acids/kg body weight per day. DESIGN:Prospective, comparative, unblinded study. SETTING:Trauma critical care units of a Level I adult trauma hospital. P...

journal_title：Critical care medicine

authors： Frankenfield DC,Reynolds HN,Wiles CE 3rd,Badellino MM,Siegel JH

更新日期：1994-03-01 00:00:00