Asymmetric division and polarity of neuroepithelial cells.

abstract：:Plasma membrane neurotransmitter transporters for monoamines, GABA, glycine and excitatory amino acids are homologous to two sizable families of bacterial amino acid transporters. Recently, a high resolution structure was determined for a thermophilic glutamate transporter. Also, a bacterial tryptophan transporter rel...

journal_title：Current opinion in neurobiology

authors： Sonders MS,Quick M,Javitch JA

更新日期：2005-06-01 00:00:00

abstract：:The aging peripheral nervous system (PNS) is prone to a number of disorders, including the development of neuropathies and increased regenerative failure. Although the basic mechanisms of the aging PNS are still rather murky, recent work has revealed that 'old' Schwann cells acquire a number of dysfunctions in mammals...

journal_title：Current opinion in neurobiology

authors： Painter MW

更新日期：2017-12-01 00:00:00

abstract：:The behavioral repertoire of an organism can be highly diverse, spanning from social to defensive. How an animal efficiently switches between distinct behaviors is a fundamental question whose inquiry will provide insights into the mechanisms that are necessary for an organism's survival. Previous work aimed at identi...

journal_title：Current opinion in neurobiology

authors： Rozeske RR,Herry C

更新日期：2018-10-01 00:00:00

abstract：:Müller Glia (MG), the radial glia cells of the retina, have spectacular morphologies subserving their enormous functional complexity. As early as 1892, the great neuroanatomist Santiago Ramon y Cajal studied the morphological development of MG, defining several steps in their morphogenesis [1,2]. However, the molecula...

journal_title：Current opinion in neurobiology

authors： MacDonald RB,Charlton-Perkins M,Harris WA

更新日期：2017-12-01 00:00:00

abstract：:The insular cortex is the primary cortical site devoted to taste processing. A large body of evidence is available for how insular neurons respond to gustatory stimulation in both anesthetized and behaving animals. Most of the reports describe broadly tuned neurons that are involved in processing the chemosensory, phy...

journal_title：Current opinion in neurobiology

authors： Maffei A,Haley M,Fontanini A

更新日期：2012-08-01 00:00:00

abstract：:Ample evidence suggests that upon their retrieval, items in long-term memory enter a transient special state, in which they might become prone to change. The process that generates this state is dubbed 'reconsolidation'. The dominant conceptual framework in this revitalized field of memory research focuses on whether ...

journal_title：Current opinion in neurobiology

authors： Dudai Y

更新日期：2006-04-01 00:00:00

abstract：:Most high-level sensory neurons have complex, nonlinear response properties; a comprehensive characterization of these properties remains a formidable challenge. Recent studies using complex sensory stimuli combined with linear and nonlinear analyses have provided new insights into the neuronal response properties in ...

journal_title：Current opinion in neurobiology

authors： Touryan J,Dan Y

更新日期：2001-08-01 00:00:00

abstract：:Mammals have ∼1000 different olfactory receptor subtypes, each responding to a number of different odorants, and each odorant activating a number of different receptor subtypes. These molecular and anatomical underpinnings of olfaction imply a perceptual structure of very high dimensionality that relies on combinatori...

journal_title：Current opinion in neurobiology

authors： Secundo L,Snitz K,Sobel N

更新日期：2014-04-01 00:00:00

abstract：:A recent flurry of genetic studies in mice have provided key insights into how the somatosensory system is organized at a cellular level to encode itch, pain, temperature, and touch. These studies are largely predicated on the idea that functional cell types can be identified by their unique developmental provenance a...

journal_title：Current opinion in neurobiology

authors： Gatto G,Smith KM,Ross SE,Goulding M

更新日期：2019-06-01 00:00:00

abstract：:The olfactory bulb and piriform cortex are the best studied structures of the mammalian olfactory system and are heavily innervated by extrinsic neuromodulatory inputs. The state-dependent release of acetylcholine, norepinephrine, serotonin, and other neuromodulators into these olfactory structures alters a constellat...

journal_title：Current opinion in neurobiology

authors： Linster C,Cleland TA

更新日期：2016-10-01 00:00:00

abstract：:Animals respond to sensory cues emitted by their conspecifics by initiating a repertoire of sex-specific social behaviors, such as mating, fighting, and parental care. These behavioral responses are thought to be largely driven by genetically pre-programmed circuits. However, they can also vary significantly according...

journal_title：Current opinion in neurobiology

authors： Li Y,Dulac C

更新日期：2018-12-01 00:00:00

abstract：:One of the seminal discoveries in developmental neuroscience is that altering visual experience through monocular deprivation can alter both the physiological and the anatomical representation of the two eyes, called ocular dominance columns, in primary visual cortex. This rearrangement is restricted to a critical per...

journal_title：Current opinion in neurobiology

authors： Feller MB,Scanziani M

更新日期：2005-02-01 00:00:00

abstract：:Biological systems use internal circadian clocks to efficiently organize physiological and behavioral activity within the 24-hour time domain. In the absence of time cues, circadian periods vary slightly from 24 hours, but in nature, ambient light serves as the most salient synchronizer for these rhythms, fine-tuning ...

journal_title：Current opinion in neurobiology

authors： Davidson AJ,Menaker M

更新日期：2003-12-01 00:00:00

abstract：:Sex steroid hormones exert a profound influence on the sexual differentiation and function of the neural circuits that mediate dimorphic behaviors. Both estrogen and testosterone are essential for male typical behaviors in many species. Recent studies with genetically modified mice provide important new insights into ...

journal_title：Current opinion in neurobiology

authors： Wu MV,Shah NM

更新日期：2011-02-01 00:00:00

abstract：:Sexual communication can evolve in response to sexual selection, and it can also cause behavioral reproductive isolation between populations and thus drive speciation. Anurans are an excellent system to investigate these links between behavior and evolution because we have detailed knowledge of how neural mechanisms g...

journal_title：Current opinion in neurobiology

authors： Ryan MJ,Guerra MA

更新日期：2014-10-01 00:00:00

abstract：:The basal ganglia, with their inhibitory efferents, control motor outputs either directly by their projections to the midbrain motor regions or indirectly through the thalamic nuclei. Neural mechanisms in the basal ganglia act selectively to remove or enhance the inhibition so that different combinations of motor sign...

journal_title：Current opinion in neurobiology

authors： Hikosaka O

更新日期：1991-12-01 00:00:00

abstract：:The use of gene transfer techniques to express novel proteins within different cellular populations has provided insights into the function and plasticity of the brain. Recently, this technique has been successfully used to explore physiological processes within the CNS and to intervene in neurodegenerative disease an...

journal_title：Current opinion in neurobiology

authors： Fisher LJ,Ray J

更新日期：1994-10-01 00:00:00

abstract：:In the last few years, work in the nascent field of neuroeconomics has advanced understanding of the brain systems involved in value-based decision making. An important modulator of valuation processes is the specific context a decision maker is facing during choice. Recently, neuroeconomics has made great progress in...

journal_title：Current opinion in neurobiology

authors： Tymula A,Plassmann H

更新日期：2016-10-01 00:00:00

abstract：:A long standing goal in motor control is to determine the fundamental output controlled by the CNS: does the CNS control the activation of individual motor units, individual muscles, groups of muscles, kinematic or dynamic features of movement, or does it simply care about accomplishing a task? Of course, the output c...

journal_title：Current opinion in neurobiology

authors： Tresch MC,Jarc A

更新日期：2009-12-01 00:00:00

abstract：:Extracting the structure of complex environments is at the core of our ability to interpret the present and predict the future. This skill is important for a range of behaviours from navigating a new city to learning music and language. Classical approaches that investigate our ability to extract the principles of org...

journal_title：Current opinion in neurobiology

authors： Kourtzi Z,Welchman AE

更新日期：2019-10-01 00:00:00

abstract：:Opiate drugs such as morphine and heroin are among the most effective analgesics known. Prolonged or repeated administration of opiates produces adaptive changes in the nervous system that lead to reduced drug potency or efficacy (tolerance), as well as physiological withdrawal symptoms and behavioral manifestations s...

journal_title：Current opinion in neurobiology

authors： von Zastrow M,Svingos A,Haberstock-Debic H,Evans C

更新日期：2003-06-01 00:00:00

abstract：:All animals have a fundamental and unavoidable requirement for rest, yet we still do not fully understand the processes that initiate, maintain, and regulate sleep. The larval zebrafish is an optically translucent, genetically tractable model organism that exhibits sleep states regulated by conserved sleep circuits, t...

journal_title：Current opinion in neurobiology

authors： Barlow IL,Rihel J

更新日期：2017-06-01 00:00:00

abstract：:Cyclic nucleotide gated (CNG) cation channels are critical for signal transduction in vertebrate visual and olfactory systems. Members of the CNG channel gene family have now been cloned from a number of species, from Caenorhabditis elegans to humans. An important advance has been the discovery that CNG channels are p...

journal_title：Current opinion in neurobiology

authors： Zufall F,Shepherd GM,Barnstable CJ

更新日期：1997-06-01 00:00:00

abstract：:The search for quantifiable biological mediators of genetic risk or 'intermediate phenotypes' is an essential strategy in psychiatric neuroscience and a useful tool for exploring the complex relationships between genes, neural circuits and behaviors. In recent years, the examination of connectivity-based intermediate ...

journal_title：Current opinion in neurobiology

authors： Cao H,Dixson L,Meyer-Lindenberg A,Tost H

更新日期：2016-02-01 00:00:00

abstract：:Despite considerable skepticism, researchers have found that the patterns of muscle activation that control feeding behaviors of lower vertebrates have been surprisingly conserved during evolution. This tendency for conservation among taxa appears in the face of marked flexibility of motor patterns within individuals....

journal_title：Current opinion in neurobiology

authors： Wainwright PC

更新日期：2002-12-01 00:00:00

abstract：:A long-standing hypothesis postulates that the striatum is essential for the concurrent selection of adaptive actions and repression of inappropriate alternatives. Here, classical and recent anatomical and physiological studies are reviewed to show that, in mammals, the striatum can detect discrete task-relevant senso...

journal_title：Current opinion in neurobiology

authors： Robbe D

更新日期：2018-10-01 00:00:00

abstract：:Tight control of developmental timing is pivotal to many major processes in developmental biology, such as patterning, fate specification, cell cycle dynamics, cell migration and connectivity. Temporal change in these ontogenetic sequences is known as heterochrony, a major force in the evolution of body plans and orga...

journal_title：Current opinion in neurobiology

authors： Bielen H,Pal S,Tole S,Houart C

更新日期：2017-02-01 00:00:00

abstract：:Parenting is essential for survival and wellbeing in many species. Since it can be performed with little prior experience and entails considerable sacrifices without immediate benefits for the caregiver, this behavior is likely orchestrated by evolutionarily shaped, hard-wired neural circuits. At the same time, experi...

journal_title：Current opinion in neurobiology

authors： Kohl J

更新日期：2020-02-01 00:00:00

abstract：:Recent advances in neural and behavioural pharmacology, and in intracellular recording suggest that arousal during the awake state may be regulated by multiple, interdependent neurotransmitter systems that originate in the brainstem or hypothalamus, and project to subcortical and cortical sites. We discuss efforts to ...

journal_title：Current opinion in neurobiology

authors： Marrocco RT,Witte EA,Davidson MC

更新日期：1994-04-01 00:00:00

abstract：:Recent autopsy and/or quantitative magnetic resonance imaging studies of autistic patients have identified agenesis of the superior olive, dysgenesis of the facial nucleus, reduced numbers of Purkinje neurons, hypoplasia of the brainstem and posterior cerebellum, and increased neuron-packing density of the medial, cor...

journal_title：Current opinion in neurobiology

authors： Courchesne E

更新日期：1997-04-01 00:00:00