Abstract:
:Recently it has been suggested that the use of alcohol-containing mouthwashes may increase the risk of oropharyngeal cancer. Heavy alcohol intake and tobacco use are established causes of oropharyngeal cancer. Their use is associated with mouthwash use. In addition, alcohol and tobacco use both tend to be underreported. Here the authors show that, under the hypothesis that mouthwash does not increase the risk of oropharyngeal cancer, confounding due to underascertained exposure to alcohol and tobacco would result in a spuriously elevated odds ratio for mouthwash use. As a general principle, a null association becomes apparently positive if a confounding variable is incompletely ascertained: a spurious association may be produced even in the absence of a difference in the extent of the underascertainment of the confounder among the comparison groups.
journal_name
Am J Epidemioljournal_title
American journal of epidemiologyauthors
Shapiro S,Castellana JV,Sprafka JMdoi
10.1093/oxfordjournals.aje.a008886subject
Has Abstractpub_date
1996-12-15 00:00:00pages
1091-5issue
12eissn
0002-9262issn
1476-6256journal_volume
144pub_type
杂志文章,评审abstract::The presence of latent tuberculosis infection (LTBI) in young children indicates recent tuberculosis (TB) transmission. We reviewed surveillance reports of children with LTBI to assess whether more follow-up is needed to prevent TB in this high-risk population. Data on all children under 5 years of age who were report...
journal_title:American journal of epidemiology
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abstract::The authors examined the relation between recreational physical activity and plasma lipid concentrations in early pregnancy. Between 1996 and 2000, 925 normotensive, nondiabetic pregnant women in Washington State were interviewed at approximately 13 weeks' gestation regarding type, frequency, and duration of physical ...
journal_title:American journal of epidemiology
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pub_type: 临床试验,杂志文章,随机对照试验
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更新日期:2002-12-01 00:00:00
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更新日期:2000-02-15 00:00:00
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