A strong secular trend in serum gamma-glutamyltransferase from 1996 to 2003 among South Korean men.

Abstract:

:Serum gamma-glutamyltransferase (GGT) concentration, within its normal range, has recently been proposed as a reliable marker of oxidative stress. Oxidative stress plays a central pathogenic role in many metabolic and/or cardiovascular diseases, incidences of which have recently increased in South Korea. Since serum GGT has strong associations with these diseases and their risk factors, the authors hypothesized a corresponding secular trend of increasing serum GGT levels in South Korea. Study subjects were 8,072 male workers at a large steel company who were aged 24-44 years at baseline and had received annual physical examinations from 1996 to 2003. The secular trend was a 0.1066-units/liter increase in ln(GGT) level per calendar year (a 180% increase during the 7-year follow-up period) (p < 0.01). Adjustment for body mass index, alcohol consumption, smoking, exercise, and cholesterol level as time-dependent covariates did not change the results. Although cholesterol is commonly used as a marker of epidemiologic transition, there was a less dramatic secular trend in ln(serum cholesterol) level, and it disappeared after adjustment for the secular trend in serum GGT. These findings suggest that serum GGT concentration can be used as a sensitive marker of epidemiologic transition, and they portend a continuing rise in incidences of metabolic and/or cardiovascular diseases in this population in the coming years.

journal_name

Am J Epidemiol

authors

Lee DH,Ha MH,Kam S,Chun B,Lee J,Song K,Boo Y,Steffen L,Jacobs DR Jr

doi

10.1093/aje/kwj006

subject

Has Abstract

pub_date

2006-01-01 00:00:00

pages

57-65

issue

1

eissn

0002-9262

issn

1476-6256

pii

kwj006

journal_volume

163

pub_type

杂志文章
  • Smoking as a risk factor in cancer of the cervix: additional evidence from a case-control study.

    abstract::The results of a case-control study in Toronto, Canada, demonstrated a two-fold risk of invasive squamous cell carcinoma of the cervix among current smokers relative to women who had never smoked. This significant effect of smoking was not diminished by simultaneously adjusting for age, education, and indices of sexua...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.aje.a113279

    authors: Clarke EA,Morgan RW,Newman AM

    更新日期:1982-01-01 00:00:00

  • The virology of variola minor. Correlation of laboratory tests with the geographic distribution and human virulence of variola isolates.

    abstract::Several groups of variola isolates were compared in DNA structure, and by four independent biologic markers. Isolates of variola minor from Europe and South America (alastrim virus) could be distinguished from African isolates of variola minor by DNA structure and by two of the four biologic markers. Taken as a group,...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.aje.a114255

    authors: Dumbell KR,Huq F

    更新日期:1986-03-01 00:00:00

  • Polyunsaturated fatty acids, antioxidants, and cognitive function in very old men.

    abstract::Atherosclerosis and thrombosis may lead to cognitive impairment through cerebral infarcts or white matter hyperintensities. Oxidative stress is now seen as a major contributor to the process of atherogenesis. High intake of polyunsaturated fatty acids, e.g., linoleic acid, or low intake of antioxidants can increase ox...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.aje.a009029

    authors: Kalmijn S,Feskens EJ,Launer LJ,Kromhout D

    更新日期:1997-01-01 00:00:00

  • Characteristics relating to ovarian cancer risk: collaborative analysis of 12 US case-control studies. I. Methods. Collaborative Ovarian Cancer Group.

    abstract::Data from 12 US case-control studies of ovarian cancer, conducted during the period 1956-1986 and representing some 3,000 cases and 10,000 controls, were pooled and reanalyzed. Separate analyses were conducted for four subgroups of the pooled data: invasive epithelial ovarian cancers in white women; epithelial ovarian...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章,meta分析

    doi:10.1093/oxfordjournals.aje.a116426

    authors: Whittemore AS,Harris R,Itnyre J,Halpern J

    更新日期:1992-11-15 00:00:00

  • Serum phosphorus levels and the spectrum of ankle-brachial index in older men: the Osteoporotic Fractures in Men (MrOS) study.

    abstract::A higher serum phosphorus level is associated with cardiovascular disease (CVD) events among community-living populations. Mechanisms are unknown. The ankle-brachial index (ABI) provides information on both atherosclerosis and arterial stiffness. In this cross-sectional study (2000-2002), the authors evaluated the ass...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/aje/kwq020

    authors: Meng J,Wassel CL,Kestenbaum BR,Collins TC,Criqui MH,Lewis CE,Cummings SR,Ix JH,Osteoporotic Fractures in Men (MrOS) Study Group.

    更新日期:2010-04-15 00:00:00

  • Invited Commentary: When Case-Control Studies Came of Age.

    abstract::In his 1976 paper "Estimability and Estimation in Case-Referent Studies" (Am J Epidemiol. 1976;103(2):226-235), Miettinen weaved together a patchwork of new ideas into a coherent view of case-control studies. His article spurred theoretical development in epidemiologic methods and became a platform for teaching about ...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/aje/kwx074

    authors: Rothman KJ

    更新日期:2017-06-01 00:00:00

  • Can the Risk of Severe Depression-Related Outcomes be Reduced by Tailoring the Antidepressant Therapy to Patient Characteristics?

    abstract::Selective serotonin reuptake inhibitors (SSRIs) are the first-line treatment for patients with unipolar depression, yet there is little guidance on which SSRI provides the most benefit to a patient, based on her/his personal characteristics. In this work, we explore whether an individualized treatment strategy can be ...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/aje/kwaa260

    authors: Coulombe J,Moodie EEM,Shortreed SM,Renoux C

    更新日期:2020-12-09 00:00:00

  • Factors associated with functional decline and improvement in a very elderly community-dwelling population.

    abstract::The objective of this study was to analyze the factors associated with functional decline and improvement in a community-dwelling population of people aged 75 years and older. A representative sample of elderly people living at home in the city of Sherbrooke (Quebec, Canada) was assessed yearly on three occasions (199...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.aje.a010039

    authors: Hébert R,Brayne C,Spiegelhalter D

    更新日期:1999-09-01 00:00:00

  • Prevalence, detection, and control of hypertension in a biethnic community. The San Antonio Heart Study.

    abstract::A survey was carried out on a random sample of 1,288 Mexican Americans and 929 Anglos living in three socially distinct neighborhoods in San Antonio, Texas. Hypertension was defined as diastolic blood pressure greater than or equal to 95 mmHg or currently taking antihypertensive medication. Overall age-adjusted preval...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/aje/121.5.684

    authors: Franco LJ,Stern MP,Rosenthal M,Haffner SM,Hazuda HP,Comeaux PJ

    更新日期:1985-05-01 00:00:00

  • A prospective study of the synergistic effects of arsenic exposure and smoking, sun exposure, fertilizer use, and pesticide use on risk of premalignant skin lesions in Bangladeshi men.

    abstract::Skin lesions are classic clinical signs of toxicity due to long-term exposure to arsenic, and they are considered precursors to arsenic-related skin cancer. The authors prospectively evaluated synergisms between effects of arsenic exposure and those of tobacco use, sun exposure, and pesticide and fertilizer use on inc...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/aje/kwq357

    authors: Melkonian S,Argos M,Pierce BL,Chen Y,Islam T,Ahmed A,Syed EH,Parvez F,Graziano J,Rathouz PJ,Ahsan H

    更新日期:2011-01-15 00:00:00

  • Cigarette smoking and breast cancer.

    abstract::The relation between cigarette smoking and the risk of breast cancer in women was investigated in a population-based case-control study conducted in Adelaide, Australia during 1982-1984. Cases were identified through the South Australian Central Cancer Registry, and, for each case, one age-matched control was selected...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.aje.a115122

    authors: Rohan TE,Baron JA

    更新日期:1989-01-01 00:00:00

  • Periconceptional dietary intake of choline and betaine and neural tube defects in offspring.

    abstract::Periconceptional intake of folic acid prevents some neural tube defects (NTDs). Other nutrients may also contribute to NTD etiologies; a likely candidate is choline. Similar to folic acid, choline is involved in one-carbon metabolism for methylation of homocysteine to methionine. The authors investigated whether mater...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/aje/kwh187

    authors: Shaw GM,Carmichael SL,Yang W,Selvin S,Schaffer DM

    更新日期:2004-07-15 00:00:00

  • Validity and reliability of self-reported diabetes in the Atherosclerosis Risk in Communities Study.

    abstract::The objective of this study was to assess the validity of prevalent and incident self-reported diabetes compared with multiple reference definitions and to assess the reliability (repeatability) of a self-reported diagnosis of diabetes. Data from 10,321 participants in the Atherosclerosis Risk in Communities (ARIC) St...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章,多中心研究

    doi:10.1093/aje/kws156

    authors: Schneider AL,Pankow JS,Heiss G,Selvin E

    更新日期:2012-10-15 00:00:00

  • History of diabetes mellitus and risk of prostate cancer in physicians.

    abstract::Some studies have suggested that diabetes mellitus may decrease the risk of prostate cancer because of lower insulin levels. To further investigate the relation between diabetes and prostate cancer, a nested case-control study was conducted within the US Physicians' Health Study. Cases (n = 1,110) had been diagnosed w...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/aje/kwh139

    authors: Zhu K,Lee IM,Sesso HD,Buring JE,Levine RS,Gaziano JM

    更新日期:2004-05-15 00:00:00

  • Relation of cigarette smoking to 25-year mortality in middle-aged men with low baseline serum cholesterol: the Chicago Heart Association Detection Project in Industry.

    abstract::It has been suggested that smoking does not influence risk of cardiovascular diseases in populations with low serum cholesterol levels. To determine whether cigarette smoking is an independent risk factor among men with low levels of serum cholesterol, data on 25-year coronary, cardiovascular, and all-cause mortality ...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/aje/155.4.354

    authors: Blanco-Cedres L,Daviglus ML,Garside DB,Liu K,Pirzada A,Stamler J,Greenland P

    更新日期:2002-02-15 00:00:00

  • Air pollution and respiratory morbidity among adults in southern California.

    abstract::This paper reports the results of an investigation of the acute effects of air pollution in 321 nonsmoking adults residing in Southern California. Previous epidemiologic investigations of effects of acute exposure to ozone have focused on groups who may not be representative of the general public, such as asthmatics o...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.aje.a116729

    authors: Ostro BD,Lipsett MJ,Mann JK,Krupnick A,Harrington W

    更新日期:1993-04-01 00:00:00

  • Cigarette-smoking and nonfatal myocardial infarction: rate ratio in relation to age, sex and predisposing conditions.

    abstract::The relationship of cigarette-smoking and nonfatal myocardial infarction (AMI) was evaluated using the case-control approach. Overall, the association was present for smokers of one and two packs per day, the standardized rate-ratio estimates being 1.5 and 1.7, respectively. The association was strongest in those who ...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.aje.a112202

    authors: Miettinen OS,Neff RK,Jick H

    更新日期:1976-01-01 00:00:00

  • Erythema chronicum migrans and Lyme arthritis: epidemiologic evidence for a tick vector.

    abstract::Forty-three residents of 12 contiguous Connecticut communities were identified who had the onset of erythema chronicum migrans, Lyme arthritis, or both during the summer and fall of 1977. Nine of them (21%) remembered having been bitten by a tick at the site of the initial skin lesion a median of 12 days (range 3-20) ...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.aje.a112625

    authors: Steere AC,Broderick TF,Malawista SE

    更新日期:1978-10-01 00:00:00

  • Tree-based, two-stage risk factor analysis for spontaneous abortion.

    abstract::The authors utilize an analytic strategy that combines tree-based analyses with the method of Mantel-Haenszel to evaluate the association of 11 putative risk factors to spontaneous abortion by controlling for 19 potential confounders. Logistic regression is also used for comparison. The data for this study were collec...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.aje.a008869

    authors: Zhang H,Bracken MB

    更新日期:1996-11-15 00:00:00

  • Relation between body mass index and lung cancer risk in men and women never and former smokers.

    abstract::The authors assessed body mass index (BMI), measured as Quetelet's index (weight in kilograms divided by the square of height in meters), in relation to lung cancer risk in never and former smokers by using data from a population-based, individually matched, case-control study conducted in New York State from 1982 to ...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/aje/152.6.506

    authors: Rauscher GH,Mayne ST,Janerich DT

    更新日期:2000-09-15 00:00:00

  • Adult-onset vulvodynia in relation to childhood violence victimization.

    abstract::Researchers have failed to find a consistent association between childhood victimization and vulvodynia, a debilitating, unexplained vulvar pain condition. However, selection bias associated with case ascertainment, and differential reporting bias between clinic-based cases and controls, may explain in part the incons...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/aje/kwi108

    authors: Harlow BL,Stewart EG

    更新日期:2005-05-01 00:00:00

  • Comparing mean levels of total cholesterol from visit 2 of the Lipid Research Clinics Prevalence Study with the second National Health and Nutrition Examination Survey.

    abstract::Mean levels of total cholesterol by sex and age were compared between groups of whites in visit 2 of the Lipid Research Clinics Program Prevalence Study and in the second National Health and Nutrition Examination Survey (NHANES II). NHANES II estimates were found to be higher than comparable visit 2 estimates by 3-14 ...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.aje.a115048

    authors: Kalsbeek WD,Kral KM,Wallace RB,Rifkind BM

    更新日期:1988-11-01 00:00:00

  • Sensitivity analysis using elicited expert information for inference with coarsened data: illustration of censored discrete event times in the AIDS Link to Intravenous Experience (ALIVE) Study.

    abstract::In this paper, the authors use the rubric of "coarsened data," of which missing and censored data are special cases, to motivate the elicitation and use of expert information for performing sensitivity analyses of censored event-time data. Elicited information is important because observed data are insufficient to est...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章,评审

    doi:10.1093/aje/kwn265

    authors: Shardell M,Scharfstein DO,Vlahov D,Galai N

    更新日期:2008-12-15 00:00:00

  • Oral contraceptives and ovulatory causes of delayed fertility.

    abstract::The return of fertility for women who discontinue oral contraceptives takes longer as compared with women who discontinue other methods of contraception. It remains unclear, however, whether subsequent fertility differs according to duration or age at first use. The authors performed a nested case-control study within...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.aje.a009261

    authors: Chasan-Taber L,Willett WC,Stampfer MJ,Spiegelman D,Rosner BA,Hunter DJ,Colditz GA,Manson JE

    更新日期:1997-08-01 00:00:00

  • Racial variations in vision.

    abstract::This study determined the distributions of uncorrected visual acuity and of refractive error in representative groups of Australian Aborigines and Australians of European origin aged 20-30 years. The methodology used in this study and its verification are described in detail. As a group, the Aborigines have significan...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.aje.a113067

    authors: Taylor HR

    更新日期:1981-01-01 00:00:00

  • Characteristics of hepatitis C virus among intravenous drug users in Iceland.

    abstract::According to antibody analysis, approximately two of every three intravenous drug users in Iceland have become infected with hepatitis C virus (HCV). In this study, serum samples from 55 HCV antibody-positive intravenous drug users (39 males and 16 females) were analyzed by polymerase chain reaction, and the viral str...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.aje.a008793

    authors: Löve A,Sigurdsson JR,Stanzeit B,Briem H,Rikardsdottir H,Widell A

    更新日期:1996-03-15 00:00:00

  • History-adjusted marginal structural models for estimating time-varying effect modification.

    abstract::Much of epidemiology and clinical medicine is focused on estimating the effects of treatments or interventions administered over time. In such settings of longitudinal treatment, time-dependent confounding is often an important source of bias. Marginal structural models (MSMs) are a powerful tool for estimating the ca...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/aje/kwm232

    authors: Petersen ML,Deeks SG,Martin JN,van der Laan MJ

    更新日期:2007-11-01 00:00:00

  • Antibody against hepatitis A in seven European countries. II. Statistical analysis of cross-sectional surveys.

    abstract::The age-specific prevalence of hepatitis A antibodies has been analyzed using a catalytic epidemic model for populations in seven European countries: West Germany, Norway, Greece, Switzerland, Holland, France and Sweden. The results indicate a significant decline in the force of infection in recent decades. However, t...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.aje.a112790

    authors: Schenzle D,Dietz K,Frösner GG

    更新日期:1979-07-01 00:00:00

  • Epidemic acute infectious nonbacterial gastroenteritis at the Children's Asthma Research Institute and Hospital.

    abstract::During the period from September 8 to October 2, 1970, 44 of the 120 children and 78 of 141 adults questioned at the Children's Asthma Research Institute and Hospital experienced gastroenteritis characterized by nausea, vomiting, and fever and/or chills. Diarrhea was rare in children (4.5%) and common in adults (74%)....

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.aje.a112154

    authors: Judson FN,Molk L

    更新日期:1975-09-01 00:00:00

  • Fungus spores, air pollutants, and other determinants of peak expiratory flow rate in children.

    abstract::The impact of summertime haze episodes on daily variations in symptoms and peak expiratory flow rates (PEFRs) was examined in a study of 108 children living in State College, Pennsylvania, during the summer of 1991. Twice daily, each child recorded symptoms, PEFRs and hours spent outdoors. Environmental measurements i...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.aje.a008818

    authors: Neas LM,Dockery DW,Burge H,Koutrakis P,Speizer FE

    更新日期:1996-04-15 00:00:00