Abstract:
OBJECTIVES:To determine whether the prostate has lymphatic/lymph node drainage that is not sampled by conventional lymphadenectomy and whether the transition and peripheral zones of the prostate have a different lymphatic drainage, because up to one quarter of lymph-node-negative patients who undergo radical prostatectomy will develop distant metastases. METHODS:Ten patients (mean age 62.3 years, range 50 to 76) scheduled for transrectal ultrasound-guided sextant biopsy because of an elevated serum prostate-specific antigen level of 4 to 10 ng/mL and a normal digital rectal examination were included in this study. All patients underwent ultrasound-guided sextant biopsies. Subsequently, an oily contrast medium was injected into the transition zone (group A, n = 5) or peripheral zone (group B, n = 5) of the prostate under transrectal ultrasound guidance and fluoroscopy. Immediately, 1 hour, and 24 hours after the procedure, anteroposterior and lateral radiographs were obtained. In addition, spiral computed tomography of the abdomen was performed 10 minutes after the procedure and analyzed on a three-dimensional workstation. RESULTS:No difference in the lymphatic drainage system between the transition and peripheral zones of the prostate was found. In all patients (n = 10), the lymphatic drainage comprised three major routes: (1) the prostate to the lymph nodes along the lateral bony wall of the pelvis to the angle of internal/external iliac lymph nodes to the common iliac lymph nodes, (2) the prostate to the perineal floor to the pudenda internal lymph nodes to the angle of the internal/external iliac lymph nodes to the common iliac lymph nodes, and (3) the prostate to the sacral lymph nodes. In all 10 patients, main contrast medium enhancement was seen immediately after procedure indicating drainage from the prostate to the lymph nodes along the lateral bony wall of the pelvis. Presacral lymph node enhancement was seen in all patients only in the late (24 hours after contrast injection) radiograph. CONCLUSIONS:Our data suggest that the main lymphatic drainage, irrespective of the prostatic region (transition or peripheral zone), runs to the pelvic regions that are mostly removed by standard lymphadenectomy techniques. However, one has to bear in mind that the prostate has some lymphatic drainage that is not covered by standard lymphadenectomy and therefore carries the risk of metastatic tumor spread.
journal_name
Urologyjournal_title
Urologyauthors
Brössner C,Ringhofer H,Hernady T,Kuber W,Madersbacher S,Pycha Adoi
10.1016/s0090-4295(00)00921-3subject
Has Abstractpub_date
2001-02-01 00:00:00pages
389-93issue
2eissn
0090-4295issn
1527-9995pii
S0090-4295(00)00921-3journal_volume
57pub_type
杂志文章相关文献
UROLOGY文献大全abstract:OBJECTIVES:To describe the patient characteristics, physical examination and magnetic resonance imaging findings, and method of surgical repair of perineocele. A perineocele is a rare condition of an isolated central defect and herniation of the posterior perineum in patients without diffuse vaginal prolapse. METHODS:...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/j.urology.2005.08.060
更新日期:2006-02-01 00:00:00
abstract:OBJECTIVE:To review the long-term outcome of selective renal arterial embolization (SAE) in treating renal angiomyolipomas (AMLs) in both elective and emergency settings. MATERIALS AND METHODS:Between October 1988 and September 2008, 27 patients (28 renal units) were treated with SAE, either on an emergency basis for ...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/j.urology.2010.08.040
更新日期:2011-03-01 00:00:00
abstract:OBJECTIVES:To determine the clinical implication of the loss of transforming growth factor-beta (TGF-beta) receptor (TbetaR) expression for the pathologic features in renal cell carcinoma (RCC) and the prognosis of 62 patients (Stage I, 4; Stage II, 28; Stage III, 11; and Stage IV, 19) who underwent radical nephrectomy...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/s0090-4295(02)02553-0
更新日期:2003-05-01 00:00:00
abstract::Automated flow cytometry (FCM) has been used to monitor the effects of therapy and progression of human bladder carcinoma. We have previously reported a computer-based model which has shown a correlation to relative mean DNA content in cell populations analyzed by FCM. Two patients with superficial transitional cell c...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/0090-4295(87)90394-3
更新日期:1987-11-01 00:00:00
abstract:OBJECTIVE:To report a new technique to reconstruct the abdominal wall at the site of the hernia with 2 separate layers of human acellular dermal matrix (hADM). Parastomal hernia is the most commonly encountered complication of ileal conduit urinary diversion, occurring at a rate of 5%-25%. Multiple methods of parastoma...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/j.urology.2010.05.003
更新日期:2011-03-01 00:00:00
abstract:OBJECTIVES:To assess the influence of intravesical instillation of epirubicin or bacille Calmette-Guérin (BCG) in patients with bladder cancer on the clinical performance of the uCyt+ test, which traces the three monoclonal antibodies M344, LDQ 10, and 19A211 in urothelial cells. METHODS:A total of 267 patients with a...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/j.urology.2003.12.023
更新日期:2004-05-01 00:00:00
abstract:OBJECTIVE:To evaluate the feasibility of pure robotic natural orifice translumenal endoscopic surgery (R-NOTES) nephrectomy. METHODS:Two R-NOTES nephrectomy approaches were attempted in 3 female cadavers. A single-port device was inserted through an incision in the posterior vaginal fornix. In the first approach, the ...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/j.urology.2012.11.083
更新日期:2013-06-01 00:00:00
abstract:OBJECTIVE:To report 3-year outcomes of a prospective, multicenter, randomized, blinded control trial after treatment with convective radiofrequency (RF) water vapor thermal therapy for moderate to severe lower urinary tract symptoms due to benign prostatic hyperplasia (BPH). MATERIALS AND METHODS:Fifteen centers enrol...
journal_title:Urology
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1016/j.urology.2017.10.023
更新日期:2018-01-01 00:00:00
abstract:OBJECTIVE:To investigate the long-term durability of retropubic suburethral sling procedure for female stress urinary incontinence (SUI) and to identify urodynamic factors that might predict long-term successful outcomes. MATERIALS AND METHODS:In total, 286 women who underwent a retropubic suburethral sling for SUI we...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/j.urology.2019.05.015
更新日期:2019-09-01 00:00:00
abstract::This is the first reported case of recurrent stress urinary incontinence secondary to dislodged bone-anchoring screws. A 71-year-old man who had undergone successful bone-anchored sling placement for post-prostatectomy incontinence, presented with recurrent stress urinary incontinence after a bout of coughing. Pelvic ...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/j.urology.2008.01.030
更新日期:2008-11-01 00:00:00
abstract::Trimethoprim recently has been released by the Food and Drug Administration (FDA) exclusively for the treatment of acute symptomatic uncomplicated bacterial urinary tract infections. The compound compares favorably with alternative standard agents, such as ampicillin and cephalexin, for the therapy of women with acute...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/0090-4295(81)90190-4
更新日期:1981-05-01 00:00:00
abstract:OBJECTIVES:To determine the hormonal (luteinizing hormone [LH] and testosterone) and biochemical (serum prostate-specific antigen [PSA]) response to withdrawal of luteinizing hormone-releasing hormone (LHRH) agonists in patients who received more than 2 years of LHRH therapy for advanced prostate cancer. METHODS:Fourt...
journal_title:Urology
pub_type: 临床试验,杂志文章
doi:10.1016/s0090-4295(99)00061-8
更新日期:1999-05-01 00:00:00
abstract::Testicular tumors are found in approximately 2 per 100,000 population. An extremely rare occurrence of synchronous testicular tumor in identical twins is presented. A complete review of the world literature with regard to testes tumors in brothers and twins is also given. ...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/0090-4295(75)90814-6
更新日期:1975-12-01 00:00:00
abstract:OBJECTIVES:To define the likelihood of nitrate users wishing to use sildenafil citrate being permitted by their nitrate-prescribing physicians to cease nitrate use, and to attempt to derive predictors of a "no" response to this request. METHODS:A total of 248 patients with erectile dysfunction were included in this st...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/j.urology.2007.01.029
更新日期:2007-05-01 00:00:00
abstract:OBJECTIVES:To develop a novel therapeutic strategy against human bladder cancer using Ad-MK-E1a-a midkine (MK) promoter-regulated, conditionally replicating, adenovirus. METHODS:We tested several human cancer cell lines in vitro, including those of bladder cancer (KK47, 5637, and T24), lung cancer (A549), and head and...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/j.urology.2007.07.003
更新日期:2007-11-01 00:00:00
abstract:OBJECTIVES:To determine whether molecular and histopathologic tumor features can predict disease progression in Stage T1 transitional cell carcinoma of the bladder. METHODS:Tumor specimens from 43 patients were analyzed with respect to grade, presence of carcinoma in situ, invasion deep or superficial to the lamina pr...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/s0090-4295(00)00756-1
更新日期:2000-11-01 00:00:00
abstract:OBJECTIVES:Elevated tumor markers after primary chemotherapy for metastatic testis cancer are usually an indication of persistent cancer. Subsequent treatment has usually been salvage chemotherapy. This article examines the possibility that selected patients can achieve long-term disease-free survival with surgery alon...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/S0090-4295(97)00458-5
更新日期:1997-12-01 00:00:00
abstract:OBJECTIVES:A critical pathway was developed to determine whether open pyeloplasty could be performed in preadolescent and adolescent children with ureteropelvic junction (UPJ) obstruction with patients safely discharged after a 1-day hospitalization. METHODS:Twenty-six consecutive children who underwent open dismember...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/j.urology.2005.07.044
更新日期:2006-01-01 00:00:00
abstract:OBJECTIVES:An association between prostatitis and male infertility has been suspected, yet is poorly understood. Prostatitis is often associated with granulocytes in the prostatic fluid that generate reactive oxygen species (ROS), known to impair male fertility. We compared ROS, the total antioxidant capacity (TAC), an...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/s0090-4295(99)00613-5
更新日期:2000-06-01 00:00:00
abstract::To determine whether a significant percentage of patients with a benign digital rectal examination (DRE) and an elevated serum prostate-specific antigen (PSA) level harbor a prostatic malignancy, 100 consecutive patients underwent transrectal ultrasound (TRUS)-guided biopsy of the prostate. The biopsy results were cor...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/0090-4295(93)90638-q
更新日期:1993-08-01 00:00:00
abstract::Hematuria and proteinuria have been noted in athletes after heavy exercise. Evaluation of 383 marathoners after a 26-mile, 385-yard run revealed hematuria in 17 per cent and proteinuria in 30 per cent. These abnormalities were not related to sex. The condition is transient and appears to be benign. A diagnostic approa...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/0090-4295(80)90007-2
更新日期:1980-05-01 00:00:00
abstract:OBJECTIVES:To substantiate claims for treatment, patients may overestimate treatment effects. Consequently, in funding debates, the question becomes whether the general public agrees on the value of a treatment. Unfortunately, little is known about the social values for treatments of erectile dysfunction (ED). To solve...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/s0090-4295(02)02516-5
更新日期:2003-04-01 00:00:00
abstract::To evaluate the cost-effectiveness of liver and bone isotope scans, results of scans were reviewed in 60 patients with renal cell carcinoma. In no patient did the results of the scans influence or change the treatment plan. Routine utilization of radioisotope scans as part of the preoperative evaluation of patients wi...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/0090-4295(83)90491-0
更新日期:1983-08-01 00:00:00
abstract:OBJECTIVES:To evaluate the effect of the fibrin sealant, Evicel, on the neuroregulatory control of penile erections in an experimental rat model. METHODS:Two groups of rats were used: sham-operated rats with exposure of the bilateral cavernous nerves (CNs) and application of saline vehicle (500 microL), and rats treat...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/j.urology.2008.03.046
更新日期:2008-11-01 00:00:00
abstract:OBJECTIVES:Laser tissue soldering (LTS) in the urinary tract provides an immediate leak-free seal and may avoid complications seen with conventional repair (such as fistula and stricture). We have begun a Phase I clinical trial investigating the use of LTS in performing urologic reconstructive surgery. METHODS:Ten pat...
journal_title:Urology
pub_type: 临床试验,杂志文章
doi:10.1016/s0090-4295(99)80206-4
更新日期:1995-08-01 00:00:00
abstract:OBJECTIVE:To identify and validate novel prognostic marker genes in clear cell renal cell carcinoma (RCC) that are increasingly expressed during tumor progression. METHODS:Total RNA was isolated from normal renal tissue, primary G1 and G3 tumors, 14 samples each, and 32 metastases from RCC patients. Expression profile...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/j.urology.2016.12.050
更新日期:2017-04-01 00:00:00
abstract:OBJECTIVES:To compare the biomechanical properties of allografts, autografts, and synthetic materials used in sling surgery using the Instron tensinometer. METHODS:The sling grafts we studied consisted of autologous tissues (dermis, rectus fascia, and vaginal mucosa), cadaver tissues (decellularized dermis and freeze-...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/s0090-4295(01)01205-5
更新日期:2001-09-01 00:00:00
abstract:OBJECTIVES:To determine the possible predictive values of seminal interleukin-6 (IL-6) and serum prostate-specific antigen (PSA), as well as their combined values, in differentiating between subjects with or without asymptomatic inflammatory prostatitis. METHODS:The study group consisted of 490 men (mean age 18.9 ± 1....
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/j.urology.2011.02.013
更新日期:2011-08-01 00:00:00
abstract::There is a persistent male gender predominance in urology, especially with respect to female representation in leadership. We review the current status of women in urology leadership, discuss challenges women face in leadership positions, present the case for adopting inclusive practices that increase diversity and ge...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/j.urology.2020.07.079
更新日期:2020-09-20 00:00:00
abstract::Hypernephroma arising in a kidney infiltrated by sarcoidosis is unusual. To date, there has been no such case reported. The hypernephroma was suspected by the presence of localized parenchymal calcifications and confirmed by selective renal angiography. ...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/0090-4295(93)90171-6
更新日期:1993-02-01 00:00:00