Abstract：
OBJECTIVES:An association between prostatitis and male infertility has been suspected, yet is poorly understood. Prostatitis is often associated with granulocytes in the prostatic fluid that generate reactive oxygen species (ROS), known to impair male fertility. We compared ROS, the total antioxidant capacity (TAC), and a novel index of oxidative stress (ROS-TAC score) in patients with chronic prostatitis and in healthy controls. METHODS:Semen specimens from 36 men with chronic prostatitis (National Institutes of Health category IIIa), 8 men with prostatodynia (National Institutes of Health category IIIb), and 19 controls attending our urologic clinic were examined according to the World Health Organization criteria. Leukocytospermia was measured by the Endtz test (myeloperoxidase assay). ROS and TAC production was measured by chemiluminescence assay. A composite ROS-TAC score was also calculated in patients and controls. RESULTS:The sperm concentration, percentage of motility, and morphology among the groups did not differ. The mean +/- standard error log-transformed ROS level was significantly higher in patients with leukocytospermia (3.2 +/- 0.6) than in patients without leukocytospermia (1.8 +/- 0.2; P = 0.04) and controls (1.3 +/- 0.3, P = 0.01). TAC was significantly lower in patients with or without leukocytospermia (859.69 +/- 193.0 and 914.9 +/- 65.2, respectively) than in controls (1653.98 +/- 93.6, P = 0.001). The mean ROS-TAC score of controls (50.0 +/- 4.1) was significantly higher than those of patients with chronic prostatitis and leukocytospermia (8.2 +/- 9.2) and those without leukocytospermia (34.2 +/- 2.9; P <0.001). CONCLUSIONS:Men with chronic prostatitis or prostatodynia have seminal oxidative stress, irrespective of their leukocytospermia status. These observations may help shed light on the long-standing controversy surrounding prostatitis and infertility.
journal_name
Urologyjournal_title
Urologyauthors
Pasqualotto FF,Sharma RK,Potts JM,Nelson DR,Thomas AJ,Agarwal Adoi
10.1016/s0090-4295(99)00613-5subject
Has Abstractpub_date
2000-06-01 00:00:00pages
881-5issue
6eissn
0090-4295issn
1527-9995pii
S0090429599006135journal_volume
55pub_type
杂志文章相关文献
UROLOGY文献大全abstract：:Percutaneous ureteral splinting using a modified catheter technique is described, and experience in treating 5 patients (4 with postoperative fistulas and 1 with stricture) is reported. The method offers an effective alternative to surgery in achieving ureteral splinting and renal drainage. ...
journal_title：Urology
pub_type： 杂志文章
doi：10.1016/0090-4295(77)90022-x
更新日期：1977-08-01 00:00:00
abstract：OBJECTIVES:To correlate endocrine parameters in elderly men with lower urinary tract symptoms (LUTS) to patient age and clinical parameters such as prostate volume, prostate-specific antigen (PSA) levels, and uroflowmetry and to compare the clinical and endocrinologic parameters in men with or without hypogonadism. ME...
journal_title：Urology
pub_type： 杂志文章
doi：10.1016/s0090-4295(99)00473-2
更新日期：2000-03-01 00:00:00
abstract：:The purpose of this review is to provide an analysis of recent changes in health care delivery and their implications for the future of urological practice. Google searches were conducted using keywords that served as section headings in the manuscript. The confluence of landmark changes in reimbursement, work hours, ...
journal_title：Urology
pub_type： 杂志文章,评审
doi：10.1016/j.urology.2010.11.011
更新日期：2011-03-01 00:00:00
abstract：:A patient with false elevation of serum creatinine level due to 5-fluorocytosine (5-FC) is reported. 5-FC interferes with the enzymatic method used for creatinine determination in the Kodak Ektachem analyzer. Clinicians should be aware of the potential for spurious azotemia in patients receiving 5-FC therapy for funga...
journal_title：Urology
pub_type： 杂志文章
doi：10.1016/0090-4295(90)80276-s
更新日期：1990-09-01 00:00:00
abstract：:We present an unusual case of recurrent reflux on the right side after bilateral vesicoureteroplasty with modified Hutch I technique. ...
journal_title：Urology
pub_type： 杂志文章
doi：10.1016/0090-4295(81)90266-1
更新日期：1981-04-01 00:00:00
abstract：OBJECTIVE:To address the overarching question whether chemoradiation therapy (CMT) offers overall survival (OS) similar to that of radical cystectomy (RC) in muscle-invasive bladder cancer (MIBC), we performed analyses using the National Cancer Database. MATERIALS AND METHODS:Patients diagnosed with MIBC in 2004-2014 ...
journal_title：Urology
pub_type： 杂志文章
doi：10.1016/j.urology.2019.05.062
更新日期：2019-11-01 00:00:00
abstract：OBJECTIVE:To investigate if prostate biopsy templates with fewer cores can be used during active surveillance (AS) for prostate cancer. METHODS:At present, we use an AS protocol template (ASPT) consisting of 13-17 cores. We hypothesize in the setting of known cancer, sextant (6 cores) or standard extended (10-12 cores...
journal_title：Urology
pub_type： 杂志文章
doi：10.1016/j.urology.2013.03.057
更新日期：2013-08-01 00:00:00
abstract：:Neonatal adrenal hemorrhage presenting as scrotal swelling has been reported in 17 cases, with unnecessary surgical exploration in 7. We report 2 new cases, emphasizing the knowledge of this clinical association and the role of ultrasonography in the differential diagnosis for this specific condition and in all cases ...
journal_title：Urology
pub_type： 杂志文章
doi：10.1016/s0090-4295(01)01610-7
更新日期：2002-04-01 00:00:00
abstract：:We report a case of human penile ossification with roentgenologic and histologic confirmation. The English literature is reviewed, and the pathogenesis of such a rare lesion is presented. Penile ossification appears to be an acquired metaplastic process occurring in an area of fibrosis. ...
journal_title：Urology
pub_type： 杂志文章,评审
doi：10.1016/0090-4295(90)80163-h
更新日期：1990-04-01 00:00:00
abstract：:The diagnosis of metastatic testicular carcinoma in a thirty-three-year-old man and his nineteen-year-old brother is reported. Histologically, the tumor of the older brother consisted predominantly of embryonal carcinoma with minor components of seminoma and adult teratoma; the tumor of the younger brother consisted e...
journal_title：Urology
pub_type： 杂志文章
doi：10.1016/0090-4295(88)90233-6
更新日期：1988-10-01 00:00:00
abstract：OBJECTIVES:To evaluate the effect of pyeloplasty for the treatment of ureteropelvic junction (UPJ) obstruction on adult renal function in the setting of a solitary kidney. METHODS:Since 1989, 312 patients have undergone operative intervention for UPJ obstruction. Of these, 13 patients (5 men and 8 women), aged 17 to 7...
journal_title：Urology
pub_type： 杂志文章
doi：10.1016/j.urology.2006.04.035
更新日期：2006-10-01 00:00:00
abstract：OBJECTIVE:To review the literature of 5 pediatric urology topics and conduct gender based and forecasting analyses of first and corresponding authors. METHODS:A PubMed search was performed for hypospadias, hydronephrosis, vesicoureteral reflux, bladder and bowel dysfunction, and cryptorchidism over 3 decades from 1990...
journal_title：Urology
pub_type： 杂志文章
doi：10.1016/j.urology.2020.01.037
更新日期：2020-05-01 00:00:00
abstract：OBJECTIVE:To compare modified autologous transobturator-tape (a-TOT) and transobtrator-tape (TOT) surgeries in terms of effectivity and complications. MATERIALS AND METHODS:Prospectively 117 patients (a-TOT:36,TOT:81) were enrolled in this study. A-TOT was performed with autologous fascia elongated with nonabsorbable ...
journal_title：Urology
pub_type： 杂志文章
doi：10.1016/j.urology.2020.09.018
更新日期：2020-12-01 00:00:00
abstract：:A man interested in active surveillance of low-risk prostate cancer sought a second opinion after having undergone an inappropriate metastatic evaluation that demonstrated multiple enhancing liver masses. Because of his history of splenectomy for trauma, hepatic splenosis was suspected. Despite reassurance, the patien...
journal_title：Urology
pub_type： 杂志文章
doi：10.1016/j.urology.2011.09.041
更新日期：2012-05-01 00:00:00
abstract：:The surgical riks were analyzed in 305 patients with end stage renal failure who underwent bilateral nephrectomy through midabdominal approach in preparation for kidney transplantation. The over-all mortality rate was 3.6 per cent. Age was the most significant risk factor in the mortality. Patients less than fifty yea...
journal_title：Urology
pub_type： 杂志文章
doi：10.1016/0090-4295(78)90367-9
更新日期：1978-07-01 00:00:00
abstract：:To evaluate the effect of prostaglandin inhibition on the renal blood flow of the ischemic kidney, we administered indomethacin to 10 anesthetized dogs with renal artery stenosis and contralateral nephrectomy. Following the operation to produce renal ischemia, there was an increase of blood pressure associated with an...
journal_title：Urology
pub_type： 杂志文章
doi：10.1016/0090-4295(79)90495-3
更新日期：1979-09-01 00:00:00
abstract：:A case of bilateral metachronous renal cell carcinoma with gallbladder and pancreatic metastases, presenting with hematobilia and anemia is presented. The presentation of metastatic renal cell carcinoma with hematobilia and anemia is previously unreported. This case illustrates (1) the occasionally very long interval ...
journal_title：Urology
pub_type： 杂志文章
doi：10.1016/s0090-4295(05)80084-6
更新日期：1991-08-01 00:00:00
abstract：OBJECTIVE:To evaluate the feasibility of pure robotic natural orifice translumenal endoscopic surgery (R-NOTES) nephrectomy. METHODS:Two R-NOTES nephrectomy approaches were attempted in 3 female cadavers. A single-port device was inserted through an incision in the posterior vaginal fornix. In the first approach, the ...
journal_title：Urology
pub_type： 杂志文章
doi：10.1016/j.urology.2012.11.083
更新日期：2013-06-01 00:00:00
abstract：:Computed tomography (CT) and ultrasound are emerging as useful diagnostic adjuvants in the confirmation of pelvic lipomatosis. A case of pelvic lipomatosis studied by CT and sonography is presented. These two techniques offer greater precision in the demonstration of fatty tissue density within the true pelvis. The fi...
journal_title：Urology
pub_type： 杂志文章
doi：10.1016/0090-4295(79)90543-0
更新日期：1979-12-01 00:00:00
abstract：:A supratesticular intrascrotal mass clinically mimicking a spermatocele was found to be a scrotal neoplasm histologically identified as a schwannoma. We herein present the first case of intrascrotal schwannoma to our knowledge. ...
journal_title：Urology
pub_type： 杂志文章
doi：10.1016/0090-4295(85)90135-9
更新日期：1985-09-01 00:00:00
abstract：:A 20-year-old man with Stage II nonseminomatous germ cell tumor underwent chemotherapy and multiple surgical resections of recurrent abdominal and supradiaphragmatic mature teratomas. Evaluation of a new heart murmur led to the diagnosis of tricuspid valve teratoma, which required complete valve excision and replaceme...
journal_title：Urology
pub_type： 杂志文章,评审
doi：10.1016/s0090-4295(00)00578-1
更新日期：2000-08-01 00:00:00
abstract：OBJECTIVES:To identify an optimal tumor-size breakpoint to distinguish between two groups with different prognoses in a large cohort of patients with localized renal cell carcinoma (RCC). METHODS:We reviewed the clinical records of 813 patients who had undergone surgical treatment for localized RCC from 1976 to 2000. ...
journal_title：Urology
pub_type： 杂志文章,评审
doi：10.1016/j.urology.2003.09.081
更新日期：2004-02-01 00:00:00
abstract：:A giant seminoma of undescended testis in a forty-one-year-old Japanese male with Down syndrome is reported as is a review of the literature. The relationship between Down syndrome and testicular cancer are discussed. To our knowledge this is the largest seminoma of undescended testis (weight 3,500 Gm) so far recorded...
journal_title：Urology
pub_type： 杂志文章
doi：10.1016/0090-4295(85)90301-2
更新日期：1985-06-01 00:00:00
abstract：OBJECTIVES:To review the experience of 40 consecutive patients who underwent radical retropubic prostatectomy and to determine if and how the procedure could be performed safely on an ambulatory basis. METHODS:Between June 20, 1994 and November 26, 1996, 40 consecutive men with clinically localized prostate carcinoma ...
journal_title：Urology
pub_type： 临床试验,杂志文章
doi：10.1016/s0090-4295(97)00716-4
更新日期：1998-03-01 00:00:00
abstract：OBJECTIVES:To evaluate whether the incidence of atrophy reported on sextant biopsies is associated with subsequent prostate cancer detection and to obtain a more thorough analysis of the different categories and extent of atrophy, we performed a review of benign biopsy cores. METHODS:In the Rotterdam section of the Eu...
journal_title：Urology
pub_type： 杂志文章
doi：10.1016/j.urology.2004.10.046
更新日期：2005-04-01 00:00:00
abstract：:A series of experiments has indicated that the bladder surface is lined with a sulfated polysaccharide that is capable of acting as a nonspecific antiadherence factor. It is capable of preventing the interaction of the transitional cells with many substances in urine, including bacteria, calcium, protein, and potentia...
journal_title：Urology
pub_type： 杂志文章
doi：
更新日期：1986-02-01 00:00:00
abstract：OBJECTIVES:To estimate the disease-specific survival of patients with complete removal of the seminal vesicles (SVs) at radical prostatectomy and to develop a nomogram for the prediction of SV invasion (SVI). METHODS:An analysis of 6740 patients from three institutions was performed. The primary outcome was biochemica...
journal_title：Urology
pub_type： 杂志文章,多中心研究
doi：10.1016/j.urology.2006.12.013
更新日期：2007-03-01 00:00:00
abstract：OBJECTIVE:To compare the outcomes between 2-port robot-assisted partial nephrectomy (2-portRALPN) and standard robot-assisted laparoscopic partial nephrectomy (sRALPN). METHODS:From May 2009 to February 2010, 35 2-portRALPN were done by a single surgeon in a university-based tertiary referral center. A cohort of 35 pa...
journal_title：Urology
pub_type： 杂志文章
doi：10.1016/j.urology.2010.10.046
更新日期：2011-09-01 00:00:00
abstract：:A case of basaloid carcinoma of the right epididymis in a 22-year-old Saudi man is described. The tumor presented as a painless swelling of 2 months' duration. Right inguinal orchiectomy has been performed. Microscopically, the stroma was widely infiltrated by tumor cells, with marked apoptosis and necrosis. The tumor...
journal_title：Urology
pub_type： 杂志文章
doi：10.1016/j.urology.2004.12.061
更新日期：2005-06-01 00:00:00
abstract：:The 5-year follow-up of the implantation of a UroLume double urethral stent in 2 patients with recurrent, post-traumatic urethral strictures is presented. The double implantation for each patient was done by the long extension of the urethral lesion. Only 1 patient presented a single phosphatic concretion in the impla...
journal_title：Urology
pub_type： 杂志文章
doi：10.1016/S0090-4295(97)00246-X
更新日期：1997-09-01 00:00:00
