Abstract:
OBJECTIVES:To correlate endocrine parameters in elderly men with lower urinary tract symptoms (LUTS) to patient age and clinical parameters such as prostate volume, prostate-specific antigen (PSA) levels, and uroflowmetry and to compare the clinical and endocrinologic parameters in men with or without hypogonadism. METHODS:Men (40 years old or older) with untreated LUTS as defined by an International Prostate Symptom Score (IPSS) of 7 or greater due to benign prostatic hyperplasia were included in this study and underwent the following investigations: IPSS, free uroflow study, postvoid residual volume, transrectal ultrasound for assessment of prostate volume, serum PSA determination, and an endocrine study, including testosterone, human luteinizing hormone, human follicle-stimulating hormone, prolactin, dehydroepiandrostendione-sulphate (DHEA-S), and prolactin. RESULTS:Three hundred twelve men (mean age 62.8 +/- 10.6 years, range 40 to 91) were analyzed. The serum levels of estradiol (correlation coefficient [r] = 0.19), human luteinizing hormone (r = 0.32), human follicle-stimulating hormone (r = 0.19), and DHEA-S (r = -0.39) correlated (P <0.05) with age; no such correlation was seen for testosterone (r = 0.04; P0.05) or prolactin (r = 0.09; P0.05). Estradiol (but not testosterone) correlated (r = 0.17, P = 0.01) with prostate volume. The peak flow rate and PSA did not correlate with any endocrinologic parameter. Hypogonadism (serum testosterone less than 3.0 ng/mL) was detected in 22.1% of patients and had no impact on clinical (IPSS, peak flow rate, prostate volume, and PSA level) or endocrine (human luteinizing hormone, human follicle-stimulating hormone, estradiol, prolactin, and DHEA-S) parameters. CONCLUSIONS:A number of age-related endocrine changes are seen in elderly men with LUTS. Hypogonadism is seen in approximately one fifth of elderly men with LUTS, but in our study it had no impact on symptom status, PSA level, prostate volume, uroflowmetry, or endocrine parameters.
journal_name
Urologyjournal_title
Urologyauthors
Schatzl G,Brössner C,Schmid S,Kugler W,Roehrich M,Treu T,Szalay A,Djavan B,Schmidbauer CP,Söregi S,Madersbacher Sdoi
10.1016/s0090-4295(99)00473-2subject
Has Abstractpub_date
2000-03-01 00:00:00pages
397-402issue
3eissn
0090-4295issn
1527-9995pii
S0090429599004732journal_volume
55pub_type
杂志文章相关文献
UROLOGY文献大全abstract::We present an unusual case of a fragmented, long forgotten double-J stent with incontinence as a result of partial extrusion of the lower fragment across the urinary sphincters. After reviewing the published data, incontinence as a presenting complaint, to the best of our knowledge, has not been reported for this cond...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/j.urology.2009.05.011
更新日期:2009-12-01 00:00:00
abstract:OBJECTIVE:To demonstrate the substantial litigious risks associated with vasectomy, a common urologic procedure. We examined the risk factors and types of negligence involved in vasectomy cases that go to trial and their associated outcomes. METHODS:Using the Westlaw legal database, we searched all jury verdicts and s...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/j.urology.2019.05.035
更新日期:2019-09-01 00:00:00
abstract:OBJECTIVES:To determine whether Zuidex using a non-cystoscopy mid-urethral injection technique produces as good a result (i.e. was not inferior) as Contigen injected endoscopically at the bladder neck in the treatment of urinary stress incontinence secondary to intrinsic sphincter deficiency in adult women. METHODS:A ...
journal_title:Urology
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1016/j.urology.2009.05.034
更新日期:2009-10-01 00:00:00
abstract:OBJECTIVE:To examine artificial urinary sphincter (AUS) cuff erosion intraoperative management methods: Foley catheter placement, abbreviated urethroplasty (AU), or mobilization with primary urethral anastomosis (PA). We reviewed these options to compare postoperative complications and probability of AUS reimplantation...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/j.urology.2015.11.040
更新日期:2016-04-01 00:00:00
abstract:OBJECTIVES:To evaluate the expression of p27(KIP1) and p21(CIP1) and the prognostic values of both markers in urothelial carcinoma. The expression of the cyclin-dependent kinase inhibitor p27(KIP1) characterizes early-stage and well-differentiated carcinomas of the colon, breast, and prostate and is associated with an ...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/s0090-4295(00)00678-6
更新日期:2000-10-01 00:00:00
abstract:OBJECTIVE:To assess the feasibility of laparoscopic nephrectomy with vaginal extraction in an ambulatory setting. METHODS:Two patients underwent a laparoscopic (1 was robot assisted) nephrectomy with vaginal extraction for a nonfunctioning kidney in an ambulatory setting. Both interventions were performed by the same ...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/j.urology.2014.06.084
更新日期:2014-12-01 00:00:00
abstract:OBJECTIVE:To assess the feasibility and safety of a novel flexible mini-nephroscope in minimally invasive percutaneous nephrolithotomy (PCNL). Presumably, limiting the size and number of tracts during PCNL has the potential of decreasing the morbidity of the procedure. We present our experience with this new technique....
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/j.urology.2017.01.009
更新日期:2017-05-01 00:00:00
abstract::Nocturia is a bothersome, multifactorial condition with many underlying causes and contributing factors. Nocturnal polyuria (NP; overproduction of urine at night) is a frequent component. The prevalence of nocturia increases with age; specific estimates of prevalence are influenced by frequency thresholds used to defi...
journal_title:Urology
pub_type: 杂志文章,评审
doi:10.1016/j.urology.2019.07.005
更新日期:2019-11-01 00:00:00
abstract:OBJECTIVES:To determine why the incidence of pediatric urolithiasis is less than that of adult urolithiasis, we investigated the difference in inhibition of calcium oxalate (CaOX) crystallization between pediatric and adult urinary macromolecules (UMMs). METHODS:Urinary parameters in relation to urolithiasis, the inhi...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/s0090-4295(99)00004-7
更新日期:1999-06-01 00:00:00
abstract:OBJECTIVE:To determine the longitudinal changes of benign prostate-specific antigen (BPSA) and [-2]proPSA and how these changes relate to the outcomes. These markers have been shown to be predictive of prostate cancer (CaP) and benign prostatic hyperplasia treatment; however, little is known about longitudinal changes ...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/j.urology.2011.09.056
更新日期:2012-03-01 00:00:00
abstract::Cortical and whole kidney radionuclide transit parameters were studied in 16 patients who underwent a pyeloplasty for unilateral pelviureteral junction (PUJ) obstruction. As expected, the whole kidney mean transit time was found to be very sensitive but, due to the low specificity, not very helpful in the distinction ...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/0090-4295(88)90249-x
更新日期:1988-10-01 00:00:00
abstract:OBJECTIVES:To define the safety and efficacy of a pneumatically driven, mechanical lithotriptor using nitinol probes through semirigid and actively deflectable, flexible fiberoptic endoscopes. METHODS:The Browne Pneumatic Impactor (BPI) uses standard compressed air to drive a nitinol wire along its long axis onto a ca...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/s0090-4295(94)80190-8
更新日期:1994-12-01 00:00:00
abstract:OBJECTIVE:To report on results from a new tele-urology pathway for managing hematuria consults, including a survey of patient attitudes and satisfaction with such a program. Recent guideline changes have relaxed the definition of microscopic hematuria and may have significantly increased the number of hematuria evaluat...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/j.urology.2016.04.066
更新日期:2016-11-01 00:00:00
abstract::Schwannoma of the penis is a rare tumor. We report a case of penile schwannoma in a young man who was accurately diagnosed preoperatively with the help of gray-scale and color flow Doppler ultrasonography, and confirmed by magnetic resonance imaging. The tumor was successfully resected to completion, with preservation...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/j.urology.2007.05.003
更新日期:2007-08-01 00:00:00
abstract:OBJECTIVES:Invasive penile and urethral tumors are traditionally treated with aggressive excision that requires involved organ and adjacent organ sacrifice. An alternative approach seeks to completely excise the tumor with adequate margins while preserving form and function of the organ. We present 6 patients who under...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/s0090-4295(98)00483-x
更新日期:1999-02-01 00:00:00
abstract::The concomitant existence of a branched (partial staghorn) calculus and clear cell carcinoma (hypernephroma) in the same kidney is rare. Herein, we report the eighth such case in the world literature, and to our knowledge, the first patient with a parenchymal tumor identified preoperatively. In all of the previous 7 c...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/0090-4295(90)80273-p
更新日期:1990-09-01 00:00:00
abstract::Evidence relating to the perception and view of patients and physicians on natural orifice transluminal endoscopic surgery (NOTES) and laparoendoscopic single-site surgery (LESS) was scrutinized. A comprehensive literature search was performed through PubMed. A total of 18 studies were included in the analysis. Patien...
journal_title:Urology
pub_type: 杂志文章,评审
doi:10.1016/j.urology.2012.04.002
更新日期:2012-09-01 00:00:00
abstract::In this study, a model system was designed to investigate the metastatic potential of intramuscularly implanted bladder tumor cells in mice. Of the 4 FANFT-induced murine bladder tumors investigated, MBT-2 and -8 metastasized to the lung. ...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/0090-4295(83)90235-2
更新日期:1983-11-01 00:00:00
abstract::Renal gunshot wounds resulting in a grade IV injury (AAST) should be explored only if they involve the hilum or if there are signs of suspected renal pelvis or ureteral laceration, active hemorrhage, peritonitis, or hemodynamically unstable patients (Kitrey et al, 2017).1 However, because of the paucity of cases repor...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/j.urology.2017.11.044
更新日期:2018-03-01 00:00:00
abstract:OBJECTIVES:Autologous fat has been used as a bulking implant material for stress urinary incontinence. There is considerable controversy as to the ultimate fate of the grafted fat. This study was conducted to determine the fate of autogenous fat implanted into the bladder of rats. METHODS:Two groups of adult female ra...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/s0090-4295(98)00338-0
更新日期:1998-11-01 00:00:00
abstract:OBJECTIVES:To investigate whether the excitatory amino acid receptor agonists can activate the paraventricular nucleus of the hypothalamus (PVN) and induce penile erections in the rat. METHODS:Male adult Sprague-Dawley rats were used. A 26-gauge needle was inserted into the corpus cavernosum to monitor the intracavern...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/s0090-4295(03)00411-4
更新日期:2003-09-01 00:00:00
abstract::We report an unusual case of an accessory or duplicated urethra. This case is unique because of its association with multiple urologic anomalies which made management and diagnosis of this condition unusual. The unusual combination of right ectopic ureter and left renal and ureteral agenesis in association with the ac...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/0090-4295(75)90633-0
更新日期:1975-10-01 00:00:00
abstract::A ureteroscopy for stone removal resulted in a tear of the ureter and extensive necrosis requiring ureteroneocystostomy. Urologists are urged to report complications of upper tract endoscopy and to apprise patients of the inherent dangers. ...
journal_title:Urology
pub_type: 杂志文章
doi:
更新日期:1984-03-01 00:00:00
abstract:OBJECTIVES:To examine the cellular, plasma, and urinary oxalate and erythrocyte oxalate flux in patients with calcium oxalate monohydrate (COM) stone formation vs normal controls. Pathologic oxalate clearance in humans is mostly integrated in calcium oxalate stone formation. An underlying cause of deficient oxalate cle...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/j.urology.2008.11.028
更新日期:2009-03-01 00:00:00
abstract:OBJECTIVES:To evaluate prospectively the success of scrotal incision orchiopexy (Bianchi technique) with or without inguinal hernia in patients with an undescended testis within the inguinal canal or beyond the external inguinal ring. METHODS:A total of 72 orchiopexies were performed in 56 patients with a primary unde...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/j.urology.2004.06.069
更新日期:2004-12-01 00:00:00
abstract:OBJECTIVES:To explore the mechanism for the differing nuclear morphometric results between needle biopsy and surgical specimens of the prostate. METHODS:In experiment 1, a comparison of mean nuclear area (MNA), volume-weighted mean nuclear volume (MNV), and form factor (FF) for prostatic epithelial cells was performed...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/s0090-4295(00)00583-5
更新日期:2000-08-01 00:00:00
abstract::In approximately 25% of patients with testicular germ cell tumor (GCT), the cancer metastasizes to lymph nodes and distant organs. The initial lymphatic drainage site of GCTs is the retroperitoneum. GCTs rarely involve mesenteric lymph nodes. In this study, we report a case of a 32-year-old male patient with GCT and a...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/j.urology.2013.11.003
更新日期:2014-03-01 00:00:00
abstract:OBJECTIVES:To determine the clinical and dosimetric factors that predict prostate-specific antigen (PSA) bounce after iodine-125 prostate brachytherapy and to determine the predictive value of PSA bounce relative to biochemical relapse-free survival (bRFS). METHODS:A multivariate analysis of factors thought to predict...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/j.urology.2003.08.025
更新日期:2004-01-01 00:00:00
abstract:OBJECTIVE:To analyze the vasectomy reversal (VR) outcomes specifically among patients with vasal obstructive intervals (VOIs) of >10 years. The VOI has been shown to be a significant predictor of outcome after VR. Although no strict cutoff exists, couples have frequently been discouraged from considering a VR strictly ...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/j.urology.2013.09.016
更新日期:2014-02-01 00:00:00
abstract:OBJECTIVE:To further investigate associated anomalies in exstrophy-epispadias complex (EEC) patients congenital uro-rectal malformations network (CURE-Net) database was systematically screened. In literature the EEC comprises a spectrum of anomalies, mainly occurring "isolated" without additional congenital defects. Ne...
journal_title:Urology
pub_type: 杂志文章,多中心研究
doi:10.1016/j.urology.2018.05.039
更新日期:2019-01-01 00:00:00