Autologous, cadaveric, and synthetic materials used in sling surgery: comparative biomechanical analysis.

Abstract:

OBJECTIVES:To compare the biomechanical properties of allografts, autografts, and synthetic materials used in sling surgery using the Instron tensinometer. METHODS:The sling grafts we studied consisted of autologous tissues (dermis, rectus fascia, and vaginal mucosa), cadaver tissues (decellularized dermis and freeze-dried, gamma-irradiated fascia lata), and synthetics (Gore-Tex and polypropylene mesh). The sling grafts were constructed into two types of slings: full strip sling (FSS) versus patch suture sling (PSS). The slings were loaded onto the Instron tensinometer and uniaxially loaded in tension until failure. From the load deformation curve, the mechanical properties of the sling grafts were compared. RESULTS:A total of 140 sling grafts were analyzed. In rank order for the FSSs, cadaver allografts had the strongest tensile strength followed by the synthetics and autologous tissues (P <0.05). The tensile strength of the FSSs was greater than for the PSSs for all groups (P

journal_name

Urology

journal_title

Urology

authors

Choe JM,Kothandapani R,James L,Bowling D

doi

10.1016/s0090-4295(01)01205-5

subject

Has Abstract

pub_date

2001-09-01 00:00:00

pages

482-6

issue

3

eissn

0090-4295

issn

1527-9995

pii

S0090-4295(01)01205-5

journal_volume

58

pub_type

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