Abstract:
OBJECTIVES:To compare the biomechanical properties of allografts, autografts, and synthetic materials used in sling surgery using the Instron tensinometer. METHODS:The sling grafts we studied consisted of autologous tissues (dermis, rectus fascia, and vaginal mucosa), cadaver tissues (decellularized dermis and freeze-dried, gamma-irradiated fascia lata), and synthetics (Gore-Tex and polypropylene mesh). The sling grafts were constructed into two types of slings: full strip sling (FSS) versus patch suture sling (PSS). The slings were loaded onto the Instron tensinometer and uniaxially loaded in tension until failure. From the load deformation curve, the mechanical properties of the sling grafts were compared. RESULTS:A total of 140 sling grafts were analyzed. In rank order for the FSSs, cadaver allografts had the strongest tensile strength followed by the synthetics and autologous tissues (P <0.05). The tensile strength of the FSSs was greater than for the PSSs for all groups (P =0.001). In rank order for the PSSs, the synthetics and dermal tissues (autograft and allograft) had the highest tensile strength followed by cadaver fascia lata, rectus fascia, and vaginal mucosa (P <0.05). CONCLUSIONS:The tensile strength of the FSS was greater than that of the PSS for the autograft, allograft, and synthetic tissues. The autograft and allograft tissues were significantly weaker as a PSS. The synthetics were more durable as a PSS compared with the organic tissues. When a PSS is constructed from autograft and allograft tissues, the risk of suture pull-through and recurrent stress incontinence must be considered.
journal_name
Urologyjournal_title
Urologyauthors
Choe JM,Kothandapani R,James L,Bowling Ddoi
10.1016/s0090-4295(01)01205-5subject
Has Abstractpub_date
2001-09-01 00:00:00pages
482-6issue
3eissn
0090-4295issn
1527-9995pii
S0090-4295(01)01205-5journal_volume
58pub_type
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