The efficacy, safety and durability of selective renal arterial embolization in treating symptomatic and asymptomatic renal angiomyolipoma.


OBJECTIVE:To review the long-term outcome of selective renal arterial embolization (SAE) in treating renal angiomyolipomas (AMLs) in both elective and emergency settings. MATERIALS AND METHODS:Between October 1988 and September 2008, 27 patients (28 renal units) were treated with SAE, either on an emergency basis for 15 (53.6%) bleeding AMLs or prophylactically for 13 (46.4%) asymptomatic high-risk (size >4.1 cm) AMLs. Six males and 21 females with a mean age of 46.3 years (range, 26-68) were followed for a mean period of 7.1 years (range, 1.3-20.2) for recurrence of symptoms, need for re-embolization, or need for renal surgery. SAE outcome was evaluated using the Kaplan-Meier method. Predictor(s) of outcome were identified with univariate analysis by log-rank test. RESULTS:Mean size of AMLs was 10.9 cm (range, 4-30). Eight (29.6%) patients had bilateral and 19 (70.4%) had unilateral AMLs. Seventeen (60.7%) kidneys had solitary AMLs; 11 (39.2%) kidneys had multicentric AMLs. Of the 15 bleeding AMLs, 12 (80%) patients required a blood transfusion. Twenty-six (93%) AMLs were successfully embolized in the first SAE. During follow-up, four (14.8%) patients required re-embolization. Renal surgery was required in four (14.8%) patients. From the Kaplan-Meier analysis, the overall renal surgery sparing rate at 5 years was 85% (95% CI: 71-99%), whereas the single session SAE success rate at 5 years was 63% (95% CI: 42-84%). Of all the variables, only AML >10 cm was significantly associated with the subsequent need for renal surgery (P = .03). No renal malignancy was noted at final follow-up. CONCLUSIONS:SAE is effective and durable in preventing large AMLs from bleeding, treating AMLs presenting with bleeding, and sparing the need for renal surgery.






Chan CK,Yu S,Yip S,Lee P




Has Abstract


2011-03-01 00:00:00
















  • Impact of Obesity on Perioperative Outcomes at Robotic-assisted and Open Radical Prostatectomy: Results From the National Inpatient Sample.

    abstract:OBJECTIVE:To test the effect of obesity (body mass index ≥30 kg/m2) on perioperative outcomes and total hospital charges at robot-assisted vs open radical prostatectomy (RARP vs ORP). METHODS:Within the National Inpatient Sample database (2008-2015), we identified obese vs nonobese RARP and ORP patients. Estimated ann...


    pub_type: 杂志文章


    authors: Knipper S,Mazzone E,Mistretta FA,Palumbo C,Tian Z,Briganti A,Saad F,Tilki D,Graefen M,Karakiewicz PI

    更新日期:2019-11-01 00:00:00

  • Innervation of trigonal area of canine urinary bladder.

    abstract::Adrenergic and cholinergic histochemical staining techniques and in vitro muscle strip responses to adrenergic and cholinergic stimulation and blockade have failed to demonstrate any neuromorphologic or neuropharmacologic differences between the musculature of the canine trigone and that of the underlying detrusor. Th...


    pub_type: 杂志文章


    authors: Raezer DM,Benson GS,Greenberg SH,Corriere JN Jr,Jacobowitz DM,Wein AJ

    更新日期:1976-04-01 00:00:00

  • Financial and educational costs of the residency interview process for urology applicants.

    abstract:OBJECTIVES:To investigate the financial and educational costs of the urology residency interview process, we performed a survey of the applicants to the 2006 urology match. METHODS:All applicants registered for the 2006 urology match were invited to participate. In January 2006 prior to the match, an anonymous online ...


    pub_type: 杂志文章


    authors: Kerfoot BP,Asher KP,McCullough DL

    更新日期:2008-06-01 00:00:00

  • Is the comparison of a left varicocele testis to its contralateral normal testis sufficient in determining its well-being?

    abstract:OBJECTIVE:To determine whether a size difference between a left testis involved with a varicocele and the contralateral normal testis is sufficient in its size assessment. METHODS:We reviewed all pediatric scrotal ultrasounds at Helen DeVos Children's Hospital between 2001 and 2008. Sonographic testicular measurements...


    pub_type: 杂志文章


    authors: Chen JJ,Ahn HJ,Junewick J,Posey ZQ,Rambhatla A,Steinhardt GF

    更新日期:2011-11-01 00:00:00

  • Oxytocinergic neurotransmission at the hippocampus in the central neural regulation of penile erection in the rat.

    abstract:OBJECTIVES:To investigate whether there is an oxytocinergic neurotransmission at the hippocampus involved in the central regulation of penile erection in the rat. METHODS:Male adult Sprague-Dawley (n = 27) rats anesthetized with pentobarbital were used. A 26-gauge needle was inserted into the corpus cavernosum to meas...


    pub_type: 杂志文章


    authors: Chen K,Chang LS

    更新日期:2001-07-01 00:00:00

  • Age and outcome of superficial bladder cancer treated with bacille Calmette-Guérin therapy.

    abstract:OBJECTIVES:To determine the influence of age on the outcomes of high-risk superficial bladder cancer treated with intravesical bacille Calmette-Guérin (BCG) therapy. METHODS:A total of 805 patients with multiple or recurrent high-grade Ta, T1, and/or carcinoma in situ bladder cancer received BCG therapy. The endpoints...


    pub_type: 杂志文章


    authors: Herr HW

    更新日期:2007-07-01 00:00:00

  • Heparin as antibacterial agent in rabbit bladder.

    abstract::Previous studies performed in our laboratory indicated that the primary antibacterial defense mechanism of the rabbit bladder is the antiadsorptive action of the surface mucopolysaccharide. The increased bacterial adsorption that occurs when the bladder is denuded of this layer was prevented by the instillation of hep...


    pub_type: 杂志文章


    authors: Hanno PM,Fritz R,Wein AJ,Mulholland SG

    更新日期:1978-10-01 00:00:00

  • Longitudinal Rupture of Distal Corpus Cavernosum With Concomitant Urethral Injury: An Uncommon Result of a Common Mechanism.

    abstract::Fracture of the penis is a well-recognized yet relatively uncommon urologic event. Forceful, blunt trauma with lateral bending of the penis in an erect state typically results in a transverse rupture of the tunica albuginea of the corpus cavernosum. Longitudinal tears of the corpus cavernosum are by themselves conside...


    pub_type: 杂志文章


    authors: Blair BM,Vilson F,Kocher NJ,Kloniecke E,Clark JY

    更新日期:2018-08-01 00:00:00

  • Telomere DNA content in prostate biopsies predicts early rise in prostate-specific antigen after radical prostatectomy for prostate cancer.

    abstract:OBJECTIVE:To determine whether measurement of telomere DNA content (TC) in prostate biopsy tissue predicts prostate-specific antigen (PSA) recurrence in men after undergoing radical prostatectomy for prostate cancer. METHODS:Slot blot titration assay was used to quantitate TC in archived diagnostic prostate needle bio...


    pub_type: 杂志文章


    authors: Treat EG,Heaphy CM,Massie LW,Bisoffi M,Smith AY,Davis MS,Griffith JK

    更新日期:2010-03-01 00:00:00

  • Trial endpoints for drug approval in oncology: Chemoprevention.

    abstract::As with other drugs, new drug applications for marketing approval of chemopreventive drugs must include data from adequate and well-controlled clinical trials that demonstrate effectiveness and safety for the intended use. This article summarizes the regulatory requirements for traditional marketing approval, as well ...


    pub_type: 杂志文章


    authors: Beitz J

    更新日期:2001-04-01 00:00:00

  • Pyocystis after urinary diversion for incontinence--is a concomitant cystectomy necessary?

    abstract:OBJECTIVE:To review the incidence of defunctionalized bladder-related complications in patients who have had a supravesical urinary diversion for intractable urinary incontinence without concomitant cystectomy. MATERIALS AND METHODS:We retrospectively analyzed the records of patients requiring urinary diversion for in...


    pub_type: 杂志文章


    authors: Lawrence A,Hu B,Lee O,Stone A

    更新日期:2013-11-01 00:00:00

  • Robotic-assisted laparoscopic retroperitoneal lymph node dissection.

    abstract::Minimally invasive laparoscopic techniques have been applied to the staging and treatment of testicular cancer during the performance of retroperitoneal lymph node dissection. The da Vinci Surgical System potentially improves the safety and accuracy of this approach. We present what we believe to be the first publishe...


    pub_type: 杂志文章


    authors: Davol P,Sumfest J,Rukstalis D

    更新日期:2006-01-01 00:00:00

  • Role of α-blockers in the treatment of stent-related symptoms: a prospective randomized control study.

    abstract:OBJECTIVE:To properly use the Ureteric Symptom Score Questionnaire (USSQ) to evaluate, in a randomized control study, the effect of 2 different α-blockers in improving symptoms and quality of life in patients with indwelling ureteral stents. METHODS:After institutional review board approval, 150 consecutive patients w...


    pub_type: 杂志文章,随机对照试验


    authors: Dellis AE,Keeley FX Jr,Manolas V,Skolarikos AA

    更新日期:2014-01-01 00:00:00

  • Questioning the 10-year Life Expectancy Rule for High-grade Prostate Cancer: Comparative Effectiveness of Aggressive vs Nonaggressive Treatment of High-grade Disease in Older Men With Differing Comorbid Disease Burdens.

    abstract:OBJECTIVE:To determine if the 10-year rule should apply to men with high-grade, clincially localized prostate cancer, we characterized the survival benefits of aggressive (surgery, radiation, brachytherapy) over nonaggressive treatment (watchful waiting, active surveillance) among older men with differing comorbidity a...


    pub_type: 杂志文章


    authors: Daskivich TJ,Lai J,Dick AW,Setodji CM,Hanley JM,Litwin MS,Saigal C,Urologic Disease in America Project.

    更新日期:2016-07-01 00:00:00

  • Prolaction and prostate cancer.

    abstract::The efficacy of treating carcinoma of the prostate with levodopa (L-dopa), a known inhibitor of prolactin secretion, has been tested in 11 Stage D patients who were refractory to conventional modalities. Relief of bone pain and recovery of mobility was excellent in 6, fair in 2, questionable in 1, and nonexistent in 2...


    pub_type: 杂志文章


    authors: Farnsworth WE,Gonder MJ

    更新日期:1977-07-01 00:00:00

  • Predictors of Device-related Complications After Exchange of the Pressure-regulating Balloon in Men With an Artificial Urinary Sphincter.

    abstract:OBJECTIVE:To identify patient and component specific factors that predispose patients to device-related complications when undergoing pressure-regulating balloon (PRB) exchange in men with an artificial urinary sphincter (AUS). METHOD:From 2009 to 2018, 55 patients underwent AUS revision with placement of a higher pre...


    pub_type: 杂志文章


    authors: Loh-Doyle JC,Nazemi A,Ashrafi A,Doumanian LR,Ginsberg DA,Boyd SD

    更新日期:2020-01-01 00:00:00

  • Staged Fowler-Stephens and Single-stage Laparoscopic Orchiopexy for Intra-abdominal Testes: Is There a Difference? A Single Institution Experience.

    abstract:OBJECTIVE:To compare single-stage laparoscopic orchiopexy (SSLO) and staged Fowler-Stephens (SFS) procedures in the management of intra-abdominal undescended testes, and to analyze postoperative atrophy and malpositioning as end points. MATERIALS AND METHODS:A retrospective chart review identified laparoscopic orchiop...


    pub_type: 杂志文章


    authors: Alam A,Delto JC,Blachman-Braun R,Wayne G,Mittal AG,Castellan M,Kozakowski K,Labbie A,Gosalbez R

    更新日期:2017-03-01 00:00:00

  • Persistent Dysuria in a Young Male.

    abstract::A Cowper's Duct syringocele is a rare diagnosis and currently there exists no clinical guidelines for evaluation and management. This clinical challenge illustrates the case presentation, evaluation, diagnosis, and treatment options for of a newly diagnosed Cowper's Duct syringocele. ...


    pub_type: 杂志文章


    authors: Silverii H,Houle K,Rovner E

    更新日期:2020-11-04 00:00:00

  • Urine levels of transforming growth factor-beta 1 in children with ureteropelvic junction obstruction.

    abstract:OBJECTIVES:To determine if there are measurable quantities of transforming growth factor-beta 1 (TGF-beta 1) in the urine of children with either normal or pathologic conditions of the urinary tract, specifically vesicoureteral reflux (VUR) and ureteropelvic junction obstruction (UPJO). We also sought to determine if t...


    pub_type: 杂志文章


    authors: Palmer LS,Maizels M,Kaplan WE,Firlit CF,Cheng EY

    更新日期:1997-11-01 00:00:00

  • Segmental Testicular Infarction Associated to Torsion: First Case Report in Childhood.

    abstract::Testicular torsion in children is not uncommon emergency problem which occur due to twist in the spermatic cord leading to ischemia or infarction to testicle. Hemorrhagic infarction can occur following testicular torsion is globally; however, in extremely rare situation, such infarction can be segmental. Segmental tes...


    pub_type: 杂志文章


    authors: Elifranji M,Elawad A,Stafrace S,Salle JLP,Vallasciani S

    更新日期:2020-08-10 00:00:00

  • Orthotopic neobladder and subsequent renal transplantation.

    abstract::Continent urinary diversion has become an attractive alternative to traditional conduits after cystectomy in select patients, including those awaiting renal transplantation. We report a case of a surgically anephric dialysis patient who underwent radical cystoprostatectomy with orthotopic ileal neobladder for recurren...


    pub_type: 杂志文章


    authors: Nimeh T,Ng CS,Goldfarb DA,Klein EA

    更新日期:2002-11-01 00:00:00

  • Extrafascial versus interfascial nerve-sparing technique for robotic-assisted laparoscopic prostatectomy: comparison of functional outcomes and positive surgical margins characteristics.

    abstract:OBJECTIVES:To evaluate the pathologic and functional outcomes of patients with bilateral interfascial (IF) or extrafascial nerve-sparing (EF-NSP) techniques. It is believed that the IF-NSP technique used during robotic-assisted radical prostatectomy (RARP) spares more nerve fibers, while EF dissection may lower the ris...


    pub_type: 杂志文章


    authors: Shikanov S,Woo J,Al-Ahmadie H,Katz MH,Zagaja GP,Shalhav AL,Zorn KC

    更新日期:2009-09-01 00:00:00

  • Prospective multicenter ProLase II clinical trial of neodymium:yttrium-aluminum-garnet laser prostatectomy.

    abstract:OBJECTIVES:To assess the clinical efficacy of neodymium:yttrium-aluminum-garnet (YAG) laser coagulation prostatectomy using a broad-angle, divergent-beam, side-firing fiber. METHODS:Eighty adult men with voiding symptoms caused by benign prostatic hyperplasia were enrolled in a prospective multicenter study of free-be...


    pub_type: 临床试验,杂志文章,多中心研究


    authors: Kabalin JN,Gill HS,Leach GE,Bowers GW,Nill T,Konowalchuk TW

    更新日期:1997-07-01 00:00:00

  • Long-term results of antegrade endoureterotomy using the holmium laser in patients with ureterointestinal strictures.

    abstract:OBJECTIVES:To investigate the effectiveness and morbidity of percutaneous laser endoureterotomy in the management of ureterointestinal anastomotic strictures after radical cystectomy and urinary diversion. METHODS:Between May 1997 and August 2000, 19 percutaneous endoureterotomy incisions, including 3 repeated incisio...


    pub_type: 杂志文章


    authors: Laven BA,O'Connor RC,Steinberg GD,Gerber GS

    更新日期:2001-12-01 00:00:00

  • Detection and isolation of prostate cancer cells from peripheral blood and bone marrow.

    abstract:OBJECTIVES:To detect and isolate disseminated prostate cancer cells because significant effort has been directed toward defining the characteristics of the primary tumor that predict progression, but little progress has been made on evaluating the disseminated prostate cancer cell. Prostate-specific antigen (PSA) rever...


    pub_type: 杂志文章


    authors: Ellis WJ,Pfitzenmaier J,Colli J,Arfman E,Lange PH,Vessella RL

    更新日期:2003-02-01 00:00:00

  • Laser tissue soldering in urinary tract reconstruction: first human experience.

    abstract:OBJECTIVES:Laser tissue soldering (LTS) in the urinary tract provides an immediate leak-free seal and may avoid complications seen with conventional repair (such as fistula and stricture). We have begun a Phase I clinical trial investigating the use of LTS in performing urologic reconstructive surgery. METHODS:Ten pat...


    pub_type: 临床试验,杂志文章


    authors: Kirsch AJ,Miller MI,Hensle TW,Chang DT,Shabsigh R,Olsson CA,Connor JP

    更新日期:1995-08-01 00:00:00

  • Correlation of ureteroscopic appearance with histologic grade of upper tract transitional cell carcinoma.

    abstract:OBJECTIVES:To correlate urologists' impressions of the tumor grade of upper tract tumors at ureteroscopy with the histologic findings after biopsy or resection. METHODS:A retrospective review of all patients who underwent diagnostic or therapeutic ureteroscopy for upper tract transitional cell carcinoma (TCC) between ...


    pub_type: 杂志文章


    authors: El-Hakim A,Weiss GH,Lee BR,Smith AD

    更新日期:2004-04-01 00:00:00

  • Effect of caffeine on urethral pressure.

    abstract::Urethral pressure profiles have been a useful adjunct in the study of continence. Caffeine, a known smooth muscle inhibitor and skeletal muscle stimulator, is shown to decrease the urethral pressure profile in anesthetized dogs. This would lead one to believe that the smooth muscle component of urethral tonus is the d...


    pub_type: 杂志文章


    authors: Palermo LM,Zimskind PD

    更新日期:1977-10-01 00:00:00

  • The Feasibility and Impact of a Presurgical Exercise Intervention Program (Prehabilitation) for Patients Undergoing Cystectomy for Bladder Cancer.

    abstract:OBJECTIVE:To assess the feasibility of a prehabilitation program for cystectomy patients and to determine the effectiveness of the program in improving strength and functional capacity in the peri-operative period. MATERIALS AND METHODS:This phase I/II study accrued patients ≥60 years old from January 2013 to October ...


    pub_type: 杂志文章


    authors: Kaye DR,Schafer C,Thelen-Perry S,Parker C,Iglay-Reger H,Daignault-Newton S,Qin Y,Morgan TM,Weizer AZ,Kaffenberger SD,Herrel LA,Hafez KS,Lee CT,Skolarus TA,Englesbe MJ,Montgomery JS

    更新日期:2020-11-01 00:00:00

  • Sensitivity to Change of Subdomain Question 6 of the Urogenital Distress Inventory Short Form After Sling Removal for Pain.

    abstract:OBJECTIVE:To determine the sensitivity to change of question 6 (Q6) of the modified short form version of the Urogenital Distress Inventory (UDI-6) before and after synthetic sling removal (SSR). METHODS:Following IRB approval, a prospectively maintained database of mid-urethral sling (MUS) complications identified wo...


    pub_type: 杂志文章


    authors: Wang CN,Christie AL,Zimmern PE

    更新日期:2021-01-01 00:00:00