Effect of neodymium: YAG laser on sodium hyaluronate in vitro as a model for postcapsulotomy intraocular pressure change.

Abstract:

PURPOSE:To define one possible etiology for the rise in intraocular pressure (IOP) after neodymium: YAG (Nd:YAG) laser capsulotomy and provide information for the continued investigation of this process. SETTING:Laser Center, Eye and Ear Institute, Pittsburgh, Pennsylvania. METHODS:Samples of 1% sodium hyaluronate or balanced salt solution (BSS) (control) were placed in a closed system and exposed to varying amounts of Nd:YAG energy delivered by a Coherent YAG laser. This system was hydrostatically coupled to a pressure monitor, and changes in pressure were recorded as a function of time. RESULTS:Average pressure increase was 0.140 mm Hg/mJ of YAG energy in the sodium hyaluronate samples and 0.017 mm Hg/mJ in BSS (P < .01). The relationship between total energy delivered and maximum pressure recorded for both substances was nearly linear. Further analysis of treated sodium hyaluronate samples showed that Nd:YAG energy can produce structural alterations. CONCLUSIONS:Neodymium:YAG laser energy has a pronounced effect on sodium hyaluronate that exceeds the thermal effect seen with BSS when the pressure is monitored in a closed system. These structural changes might contribute to the IOP rise seen clinically.

authors

Adams EA,Verstraeten TC,Friberg TR,Rehkopf PG,Stefanovic-Racic M

doi

10.1016/s0886-3350(96)80315-4

subject

Has Abstract

pub_date

1996-07-01 00:00:00

pages

748-51

issue

6

eissn

0886-3350

issn

1873-4502

pii

S0886-3350(96)80315-4

journal_volume

22

pub_type

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