Risk of alanine aminotransferase flare-up among asymptomatic hepatitis C virus RNA carriers: a 10-year follow-up study.

abstract：BACKGROUND AND AIM:The authors' previous report revealed that endothelin-1 might be released from B lymphocytes in cirrhotic patients with hypersplenism. Other investigators have shown that persistent exposure to environmental contaminants including arsenic might induce idiopathic portal hypertension. The aim of this s...

journal_title：Journal of gastroenterology and hepatology

authors： Yamaguchi E,Yamanoi A,Ono T,Nagasue N

更新日期：2007-07-01 00:00:00

abstract：BACKGROUND AND AIM:Nonalcoholic steatohepatitis (NASH) is a metabolic disorder of the liver that may evolve into fibrosis or cirrhosis. Recent studies have shown reduction of experimental liver fibrosis with the use of angiotensin-converting-enzyme inhibitors or angiotensin-receptor antagonists. The aim of this study w...

journal_title：Journal of gastroenterology and hepatology

authors： Ibañez P,Solis N,Pizarro M,Aguayo G,Duarte I,Miquel JF,Accatino L,Arrese M

更新日期：2007-06-01 00:00:00

abstract：BACKGROUND AND AIM:Some patients with chronic hepatitis C experience virologic relapse even after achieving an end of treatment response. Prolonged therapy can be effective for helping such high-risk patients to avoid relapse. We aimed to identify factors predictive of virologic relapse in chronic hepatitis C patients ...

journal_title：Journal of gastroenterology and hepatology

authors： Shin SR,Sinn DH,Gwak GY,Choi MS,Lee JH,Koh KC,Yoo BC,Paik SW

更新日期：2010-05-01 00:00:00

abstract：BACKGROUND AND AIMS:Upper gastrointestinal endoscopy remains the gold standard for diagnosis of esophageal varices. Trans-abdominal ultrasound, as a noninvasive routine examination for the follow-up of cirrhosis patient, is safe, cheap, easy to perform, and plays an important role. In this study, we attempt to design a...

journal_title：Journal of gastroenterology and hepatology

authors： Zhang CX,Xu JM,Li JB,Kong DR,Wang L,Xu XY,Zhao DM

更新日期：2016-01-01 00:00:00

abstract：:The immunogenicity and adverse reaction of an inactivated hepatitis A (HA) vaccine were investigated. Sixty healthy adult volunteers who lacked antibody to HA virus (anti-HAV) received three doses of vaccine containing 720 enzyme-linked immunosorbent assay (ELISA) units (EL.U) according to a 0, 1 and 6 month schedule....

journal_title：Journal of gastroenterology and hepatology

authors： Horng YC,Chang MH,Lee CY,Safary A,Andre FE,Chen DS

更新日期：1993-07-01 00:00:00

abstract：:Bleeding from hepatocellular carcinoma (HCC) invading the gastrointestinal tract is very uncommon. We report the case of a 61 year old man who had a large bleed from HCC invading the fundus of the stomach. Diagnosis was eventually made at laparotomy and he is still alive 7 months after local resection. ...

journal_title：Journal of gastroenterology and hepatology

authors： Nicoll AJ,Ireton HJ,Crotty B

更新日期：1994-09-01 00:00:00

abstract：BACKGROUND AND AIM:Symptoms and complications of primary biliary cirrhosis (PBC) have been shown to impair patients' health-related quality of life (HRQOL) in the West. We aimed to measure the HRQOL and to determine the factors associated with worse HRQOL among the Chinese PBC patients in Hong Kong. METHODS:Chinese pa...

journal_title：Journal of gastroenterology and hepatology

authors： Wong GL,Law FM,Wong VW,Hui AY,Chan FK,Sung JJ,Chan HL

更新日期：2008-04-01 00:00:00

abstract：BACKGROUND AND AIM:Inflammatory bowel disease results from a dysregulated immune response to intestinal microbial flora in individuals with genetic predisposition(s). This study aimed to determine the effects of compound polysaccharides (CP) containing yam polysaccharide and inulin on the rat model of colitis induced b...

journal_title：Journal of gastroenterology and hepatology

authors： Cai Y,Liu W,Lin Y,Zhang S,Zou B,Xiao D,Lin L,Zhong Y,Zheng H,Liao Q,Xie Z

更新日期：2019-09-01 00:00:00

abstract：BACKGROUND AND AIM:Approximately 42-95% of working channels have been reported to show the presence of residual fluid despite endoscope reprocessing. The aim of this study was to design two novel protocols for cleaning residual simethicone and demonstrate its efficiency by evaluating the residual fluid and cleanliness ...

journal_title：Journal of gastroenterology and hepatology

authors： Peng CL,Liu TC,Wang HP,Chang WK

更新日期：2020-12-03 00:00:00

abstract：BACKGROUND AND AIM:Glypican-3 (GPC3) expression is correlated with poor prognosis and progression in hepatocellular carcinoma (HCC). HCC progression can be associated with the differentiation status of tumor cell before malignant transformation. Our aim was to investigate the dynamic expression of GPC3 during tumor cel...

journal_title：Journal of gastroenterology and hepatology

authors： Xue R,Feng J,Meng Q,Lv F,Zhu Y,Yu H,Zhang S,Song C,Sun L,Yue Z,Feng S,Che R,Xiang Q,Jing X

更新日期：2017-08-01 00:00:00

abstract：BACKGROUND AND AIM:Interferon and ribavirin combination therapy for chronic hepatitis C produces hemolytic anemia. This study was conducted to identify the factors contributing to ribavirin-induced anemia. METHODS:Eighty-eight patients with chronic hepatitis C who received interferon-alpha-2b at a dose of 6 MU adminis...

journal_title：Journal of gastroenterology and hepatology

authors： Nomura H,Tanimoto H,Kajiwara E,Shimono J,Maruyama T,Yamashita N,Nagano M,Higashi M,Mukai T,Matsui Y,Hayashi J,Kashiwagi S,Ishibashi H

更新日期：2004-11-01 00:00:00

abstract：:The effects of ethanol and its metabolites on collagen synthesis in cultured rat Ito cells and hepatocytes were studied. In cultured Ito cells, collagen synthetic ability reached peak values after incubation for 24 h and after 8 h in cultured hepatocytes. The distribution patterns of 14C-activity in each collagen frac...

journal_title：Journal of gastroenterology and hepatology

authors： Tsutsumi M,Takada A,Takase S,Shimanaka K,Enyama K

更新日期：1989-05-01 00:00:00

abstract：BACKGROUND AND AIM:Mucosal injury caused by gastroesophageal reflux may result in changes in esophageal mucosal blood flow. Little is known about esophageal mucosal blood flow in patients with gastroesophageal reflux disease (GERD). Here we examined esophageal mucosal blood flow and the effects of treatment in patients...

journal_title：Journal of gastroenterology and hepatology

authors： Mine S,Iida T,Tabata T,Okada Y,Tanaka Y

更新日期：2008-02-01 00:00:00

abstract：:To ascertain whether acid inhibition or Helicobacter pylori (HP) colonization is the decisive factor in the healing of duodenal ulcer, we treated 54 patients with famotidine and carried out long-term follow-up. Helicobacter pylori colonization was found in 70.4% of patients before treatment. There were no differences ...

journal_title：Journal of gastroenterology and hepatology

authors： Lai KH,Chang FY,Tsay SH,Lu LC,Cheng JT,Jeng SS,Wu TC,Ng WW,Jeng JS,Lee SD

更新日期：1991-03-01 00:00:00

abstract：BACKGROUND AND AIM:The rate of fibrosis progression per year can predict the time for the development of cirrhosis in chronic hepatitis C (CHC). We assessed the rate of fibrosis progression and the predictors of disease severity in Indian CHC patients. METHODS:Of the 355 treatment-naïve, histologically-proven CHC pati...

journal_title：Journal of gastroenterology and hepatology

authors： Hissar SS,Kumar M,Tyagi P,Goyal A,Suneetha PV,Agarwal S,Rastogi A,Sakhuja P,Sarin SK

更新日期：2009-04-01 00:00:00

abstract：:The focus on colorectal neoplasia has led to an exponential increase in the use of colonoscopy in many countries. Although colonoscopy facilitates the diagnosis and treatment of colonic disease, there are public health issues that include access, training, diagnostic accuracy, complications and additions to health-car...

journal_title：Journal of gastroenterology and hepatology

authors： Roberts-Thomson IC,Teo E

更新日期：2009-02-01 00:00:00

abstract：:Helicobacter pylori is present in infected patients not only on the gastric epithelial cell surface but also in gastric mucus. We developed a competitive polymerase chain reaction (cPCR) method for quantitative measurement of H. pylori in gastric mucus. The aim of this study was to determine the number of H. pylori in...

journal_title：Journal of gastroenterology and hepatology

authors： Furuta T,Takashima M,Futami H,Arai H,Hanai H,Kaneko E

更新日期：1998-05-01 00:00:00

abstract：BACKGROUND AND AIM:The aim of the present study was to evaluate the frequency of complications during endoscopic ultrasound (EUS)-guided drainage of pancreatic fluid collections (PFC), identify contributing factors, and report on management outcomes. METHODS:All patients who underwent EUS-guided PFC drainage over 7 ye...

journal_title：Journal of gastroenterology and hepatology

authors： Varadarajulu S,Christein JD,Wilcox CM

更新日期：2011-10-01 00:00:00

abstract：BACKGROUND:Toll-like receptors (TLRs) are involved in innate immunity. Certain viruses interact with TLRs and mediate antiviral effects as well as immune responses. The aim of this study was to investigate the effect of TLRs on pathogenesis in hepatitis C virus (HCV)-infected patients. METHODS:Peripheral blood mononuc...

journal_title：Journal of gastroenterology and hepatology

authors： Sato K,Ishikawa T,Okumura A,Yamauchi T,Sato S,Ayada M,Matsumoto E,Hotta N,Oohashi T,Fukuzawa Y,Kakumu S

更新日期：2007-10-01 00:00:00

abstract：BACKGROUND AND AIM:The high-mobility group box 1 (HMGB1) protein plays an important role in a lot of biological behaviors, including DNA damage repair, gene transcription, cell replication, and cell death, and its expression is higher in many solid tumors tissues than in their adjacent normal tissues, and it is always ...

journal_title：Journal of gastroenterology and hepatology

authors： Di X,He G,Chen H,Zhu C,Qin Q,Yan J,Zhang X,Sun X

更新日期：2019-04-01 00:00:00

abstract：:Coffee is one of the most popular beverages in the world. Several studies consistently show that coffee drinkers with chronic liver disease have a reduced risk of cirrhosis and a lower incidence of hepatocellular carcinoma regardless of primary etiology. With the increasing prevalence of non-alcoholic fatty liver dise...

journal_title：Journal of gastroenterology and hepatology

authors： Chen S,Teoh NC,Chitturi S,Farrell GC

更新日期：2014-03-01 00:00:00

abstract：:Acid-sensing pathways, which trigger mucosal defense mechanisms in response to luminal acid, involve the rapid afferent-mediated "capsaicin pathway" and the sustained "prostaglandin (PG) pathway." Luminal acid quickly increases protective PG synthesis and release from epithelia, although the mechanism by which luminal...

journal_title：Journal of gastroenterology and hepatology

authors： Akiba Y,Kaunitz JD

更新日期：2014-12-01 00:00:00

abstract：BACKGROUND AND AIM:The present study was aimed to evaluate the hepatic zonation of multidrug resistance-associated protein 2 (mrp2), an important drug transporter, and its potential changes during the induction of its expression by known inducer, dexamethasone (DEX). METHODS:The hepatic expression of mrp2 was studied ...

journal_title：Journal of gastroenterology and hepatology

authors： Micuda S,Fuksa L,Brcakova E,Osterreicher J,Cermanova J,Cibicek N,Mokry J,Staud F,Martinkova J

更新日期：2008-07-01 00:00:00

abstract：BACKGROUND:To elucidate the cause of possible occurrence of reflux esophagitis after Helicobacter pylori eradication, gastric and esophageal function among H. pylori infected Japanese patients were evaluated both before and after eradication therapy. METHODS:Nine H. pylori-positive patients were studied before and 6 m...

journal_title：Journal of gastroenterology and hepatology

authors： Tanaka I,Tatsumi Y,Kodama T,Kato K,Fujita S,Mitsufuji S,Kashima K

更新日期：2004-03-01 00:00:00

abstract：BACKGROUND AND AIM:Patients with advanced pancreatic cancer have severe pain, anxiety, and depression, and these symptoms deteriorate quality of life (QOL). Previous study reported that early psychiatric intervention for advanced cancer patients may improve QOL. We evaluated the trajectory of health-related QOL (HRQOL)...

journal_title：Journal of gastroenterology and hepatology

authors： Sugimoto H,Kawashima H,Ohno E,Hayashi D,Kuwahara T,Morishima T,Kawai M,Suhara H,Takeyama T,Yamamura T,Funasaka K,Nakamura M,Miyahara R,Watanabe O,Ishigami M,Suzuki M,Kimura H,Ozaki N,Hashimoto S,Goto H,Hirooka Y

更新日期：2016-03-01 00:00:00

abstract：:T regulatory cells (Tregs) play an important role in the regulation of autoimmunity, autoinflammation, allergic diseases, infection, and the tumor environment. Different subsets are characterized that use a number of regulatory mechanisms. Tregs can influence the progression of inflammatory bowel disease and the devel...

journal_title：Journal of gastroenterology and hepatology

authors： van Herk EH,Te Velde AA

更新日期：2016-08-01 00:00:00

abstract：BACKGROUND AND AIM:Colorectal cancer screening is recommended for average-risk persons beginning at age 50. However, information about the incidence and risk factors of precursor adenoma in preceding decades is limited. The aim of this study was to determine the prevalence and risk factors of colorectal adenoma in pers...

journal_title：Journal of gastroenterology and hepatology

authors： Chung SJ,Kim YS,Yang SY,Song JH,Park MJ,Kim JS,Jung HC,Song IS

更新日期：2010-03-01 00:00:00

abstract：BACKGROUND AND AIM:Little is known about the role of platelet-derived growth factor (PDGF) in biliary fibrosis in the setting of bacterial colonization of the biliary tree. We therefore sought to investigate whether exposure to bacterial lipopolysaccharide (LPS) alters PDGF isoform and receptor expression in cultured r...

journal_title：Journal of gastroenterology and hepatology

authors： Kim TH,Moon JH,Savard CE,Kuver R,Lee SP

更新日期：2009-07-01 00:00:00

abstract：BACKGROUND AND AIMS:The relationship between gastroesophageal reflux disease and sliding hernia is controversial, especially following distal partial gastrectomy in patients with gastric cancer. The aim of this study was to examine the relationship between gastroesophageal reflux disease and sliding hernia of the esoph...

journal_title：Journal of gastroenterology and hepatology

authors： Fujiwara Y,Nakao K,Inoue T,Koishi K,Nishio Y,Yagyu R,Nakagawa K,Yamamura T

更新日期：2006-07-01 00:00:00

abstract：:Sensitive and specific enzyme-linked immunosorbent assays (ELISA) were developed to detect separately the binding of polymerized human serum albumin (PHSA) to its antibody (A-PHSA) and to the hepatitis B surface antigen (HBsAg). A-PHSA was not detected in normal serum, whereas more than one-third to about half of sera...

journal_title：Journal of gastroenterology and hepatology

authors： Dash S,Panda SK,Nayak NC

更新日期：1990-01-01 00:00:00